AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy(WCE)in patients with familial adenomatous polyposis(FAP).METHODS:We examined prospectively 14 patients with FAP to assess the location,s...AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy(WCE)in patients with familial adenomatous polyposis(FAP).METHODS:We examined prospectively 14 patients with FAP to assess the location,size and number of small-intestinal polyps.Patients'age,sex,years of observation after surgery,type of surgery,duodenal polyps and colorectal cancer at surgery were analyzed.RESULTS:During WCE,polyps were detected in 9/14(64.3%)patients.Duodenal adenomatous polyps were found in nine(64.3%)patients,and jejunal and ileal polyps in seven(50%)and eight(57.1%),respectively.The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps.Identification of the ampulla of Vater was not achieved with WCE.Importantly,the findings of WCE had no immediate impact on the further clinical management of FAP patients.No procedure-related complications were observed in the patients.CONCLUSION:WCE is a promising noninvasive new method for the detection of small-intestinal polyps.Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.展开更多
IAPs (inhibitors of apoptosis) are a family of proteins containing one or more characteristic BIR domains. These proteins have multiple biological activities that include binding and inhibiting caspases, regulating ce...IAPs (inhibitors of apoptosis) are a family of proteins containing one or more characteristic BIR domains. These proteins have multiple biological activities that include binding and inhibiting caspases, regulating cell cycle progression, and modulating receptor-mediated signal transduction. Our recent studies found the IAP family members XIAP and c-IAP1 are ubiquitinated and degraded in proteasomes in response to apoptotic stimuli in T cells, and their degradation appears to be important for T cells to commit to death. In addition to three BIR domains, each of these IAPs also contains a RING finger domain.We found this region confers ubiquitin protease ligase (E3) activity to IAPs, and is responsible for the auto-ubiquitination and degradation of IAPs after an apoptotic stimulus. Given the factthat IAPs can bind a variety of proteins, such as caspases and TRAFs, it will be of interest to characterize potential substrates of the E3 activity of IAPs and the effects of ubiquitination byIAPs on signal transduction, cell cycle, and apoptosis.展开更多
Everestiomyia Townsend,1933(Diptera:Tachinidae)belongs to the tribe Ernestiini in the Tachininae.One new species of this genus from the Altun Mountains of Xinjiang,western China was found and is described:Everestiomyi...Everestiomyia Townsend,1933(Diptera:Tachinidae)belongs to the tribe Ernestiini in the Tachininae.One new species of this genus from the Altun Mountains of Xinjiang,western China was found and is described:Everestiomyia nudioculata Zhang sp.nov.展开更多
The vocabulary is the most active factor in the language, and the meaning of color words in the vocabulary is abundant. The nature is multicolored, so various nationalities have formed each unique color view in precip...The vocabulary is the most active factor in the language, and the meaning of color words in the vocabulary is abundant. The nature is multicolored, so various nationalities have formed each unique color view in precipitated long-term history, refracting gorgeous national culture. Culture has restrained the meaning of the color words from developing, and the cultural meaning of the color words has refracted out abundant cultural intension again. Because of different cultural issues, cultural tradition, and culture psychology, the cultural connotations of the English and Chinese color words differ greatly, as a result, these particular cultural connotation meanings are cast under different environments by different nationalities. There are a lot of similarities and differences on the meaning between English and Chinese color words. This paper analyzing Chinese and English color terms in the angle of lexicology, is guided by the book An Introduction to English Lexicology. After reviewing the research done by some linguists, this paper starts from the definition and origin of color terms, studies the changing and word-formation of color terms, then ends with some researches on the idioms on color terms, which gives a systematically comparison of Chinese and English color terms on their developing progress.展开更多
Culture is the soul of a nation, and also the basis of landscape design, the basis of historical inheritance and innovation. Japanese garden was born out of Chinese garden, but because of the difference of geographica...Culture is the soul of a nation, and also the basis of landscape design, the basis of historical inheritance and innovation. Japanese garden was born out of Chinese garden, but because of the difference of geographical environment and national culture, Japanese gardens combine Chinese culture with local national characteristics, forming a unique garden culture in Japan. Based on the research on Japanese gardens like pond garden, rock garden and tea garden, this study analyzed the cultural connotation in Japanese garden landscape design, made in-depth understanding of Japanese landscape development, explored the value existing in the contemporary garden design of Japanese gardens, with the aim to make use of the excellent experience to the garden landscape design in the future.展开更多
Yunnan is one of the most important homes habitations for the Yi nationality of China. As one of the ethnic minorities in China, the costume of the Yi nationality is of important research value. In this paper, the aut...Yunnan is one of the most important homes habitations for the Yi nationality of China. As one of the ethnic minorities in China, the costume of the Yi nationality is of important research value. In this paper, the author emphatically analyzes the making process and cultural connotation of the Yi nationality＇s costume, and also proposes the problems and solutions in the inheritance and innovation of the Yi nationality＇s costume.展开更多
Thermal performance of envelopes and indoor thermal environment were technologically improved for traditional wooden vernacular dwellings of Tujia Minority in Western Hunan, China, on the premise of protecting their c...Thermal performance of envelopes and indoor thermal environment were technologically improved for traditional wooden vernacular dwellings of Tujia Minority in Western Hunan, China, on the premise of protecting their conventional styles. Thermal insulation boards and wooden boards were added to the interior side of external walls of vernacular dwellings to form two layers of air cavities, so as to gain excellent thermal performance. The indoor temperature of such dwellings after reconstruction was apparently improved compared with the data before reconstruction both in winter and summer, which verified the feasibility and the effectiveness of the reconstruction technologies proposed.展开更多
The paper focuses on the connotation of ethnic culture elements of college English education for Three Minority Nations in Inner Mongolia and comprehensive and scientific explanation for Three Minority Nations. Corres...The paper focuses on the connotation of ethnic culture elements of college English education for Three Minority Nations in Inner Mongolia and comprehensive and scientific explanation for Three Minority Nations. Corresponding solutions were proposed from the aspects of teachers, teaching materials, curriculum and so on and feasible suggestions were put forward for nationality culture building by the English education of Three Minority Nations in Inner Mongolia on this basis.展开更多
Chinese classical dance contains a profound connotation of Chinese traditional culture, with distinctive forms of performance and aesthetic characteristics. In the world of multi-cultttral communion, the development o...Chinese classical dance contains a profound connotation of Chinese traditional culture, with distinctive forms of performance and aesthetic characteristics. In the world of multi-cultttral communion, the development of Chinese classical dance needs to be inherited on the basis of traditional culture to inject more innovation, highlight its unique artistic aesthetic value and deep national culture contains. In this paper, the development course, aesthetic characteristics and classical dance form of Chinese classical dance are expounded. From the perspectives of historical cultural inheritance, classical dance culture cultivation and dance culture innovation, the feasibility measures and measures are put forward in order to explore the effective path and methods to developing Chinese classical dance, which gives excellent national dance art inheritance, development and innovation.展开更多
Objective To comparatively observe the effect of electroacupuncture at digestive system-related lower he-sea points on the expressions of serum interleukin-1β（IL-1 β）, tumor necrosis factor-α（TNF-α） of colon t...Objective To comparatively observe the effect of electroacupuncture at digestive system-related lower he-sea points on the expressions of serum interleukin-1β（IL-1 β）, tumor necrosis factor-α（TNF-α） of colon tissues and high mobility group box 1 protein（HMGB 1） of ulcerative colitis（UC） model rats, and to explore whether there is relative specificity of electroacupuncture at Shàngjùxū（上巨虚 ST 37）, one of lower he-sea points of large intestine, in treatment of bowel diseases. Method A total of 60 SD rats were randomly divided into control group, model group, ST 37 group, Zúsānl？（足三里 ST 36） group, Xiàjùxū（下巨虚 ST 39） group and Yánglíngquán（阳陵泉 GB 34） group. There were ten rats in each group; five were males, and five were females. UC models were established by clysis with 2, 4, 6-trinitrobenzene sulfonic acid/alcohol solution. After modeling, treatment was conducted for ten days, specimens were collected, colonic ulcers and inflammation were inspected visually and scored. The content of serum IL-1β and the expressions of TNF-α and HMGB 1 in colon were detected through ELISA. Results 1 Compared with control group, the scores of colonic ulcers and inflammation, the content of serum IL-1β and the expressions of TNF-α（except ST 37 group） and HMGB 1 were all higher（P〈0.05, P〈0.01）; 2 compared with model group, the scores of colonic ulcers in ST 36 group and ST 37 group were lower obviously（P〈0.05, P〈0.01）; the expressions of IL-1β, TNF-α and HMGB 1 in the four treatment groups were lower obviously（P〈0.01）; 3 compared with ST 37 group, the expressions of IL-1β, TNF-α and HMGB 1 in other three treatment groups were higher obviously（P〈0.05, P〈0.01）; and the scores of colonic ulcers in ST 39 group and GB 34 group were higher obviously（P〈0.05）. Conclusion 1 The score of colonic ulcers can be reduced through electroacupuncture at ST 37, ST 36, ST 39 and GB 34, which can also reduce the content of serum IL-1β and the expressions of TNF-α and HMGB 1, and effectively inhibit inflammatory response of colon caused by UC; 2 the effect trend of the four acupoints in treatment of UC is： ST 37ST 36ST 39GB 34, and electroacupuncture at ST 37 has the best effect with relative specificity.展开更多
Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulato...Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity.In this review we discuss the roles of the Eph receptors in lens biology and cataract development.展开更多
文摘AIM:To detect the prevalence of small bowel polyps by wireless capsule endoscopy(WCE)in patients with familial adenomatous polyposis(FAP).METHODS:We examined prospectively 14 patients with FAP to assess the location,size and number of small-intestinal polyps.Patients'age,sex,years of observation after surgery,type of surgery,duodenal polyps and colorectal cancer at surgery were analyzed.RESULTS:During WCE,polyps were detected in 9/14(64.3%)patients.Duodenal adenomatous polyps were found in nine(64.3%)patients,and jejunal and ileal polyps in seven(50%)and eight(57.1%),respectively.The Spigelman stage of duodenal polyposis was associated with the presence of jejunal and ileal polyps.Identification of the ampulla of Vater was not achieved with WCE.Importantly,the findings of WCE had no immediate impact on the further clinical management of FAP patients.No procedure-related complications were observed in the patients.CONCLUSION:WCE is a promising noninvasive new method for the detection of small-intestinal polyps.Further investigation is required to determine which phenotype of FAP is needed for surveillance with WCE.
文摘IAPs (inhibitors of apoptosis) are a family of proteins containing one or more characteristic BIR domains. These proteins have multiple biological activities that include binding and inhibiting caspases, regulating cell cycle progression, and modulating receptor-mediated signal transduction. Our recent studies found the IAP family members XIAP and c-IAP1 are ubiquitinated and degraded in proteasomes in response to apoptotic stimuli in T cells, and their degradation appears to be important for T cells to commit to death. In addition to three BIR domains, each of these IAPs also contains a RING finger domain.We found this region confers ubiquitin protease ligase (E3) activity to IAPs, and is responsible for the auto-ubiquitination and degradation of IAPs after an apoptotic stimulus. Given the factthat IAPs can bind a variety of proteins, such as caspases and TRAFs, it will be of interest to characterize potential substrates of the E3 activity of IAPs and the effects of ubiquitination byIAPs on signal transduction, cell cycle, and apoptosis.
基金supported by the National Natural Science Foundation of China to Chuntian ZHANG(31970443,31750002)。
文摘Everestiomyia Townsend,1933(Diptera:Tachinidae)belongs to the tribe Ernestiini in the Tachininae.One new species of this genus from the Altun Mountains of Xinjiang,western China was found and is described:Everestiomyia nudioculata Zhang sp.nov.
文摘The vocabulary is the most active factor in the language, and the meaning of color words in the vocabulary is abundant. The nature is multicolored, so various nationalities have formed each unique color view in precipitated long-term history, refracting gorgeous national culture. Culture has restrained the meaning of the color words from developing, and the cultural meaning of the color words has refracted out abundant cultural intension again. Because of different cultural issues, cultural tradition, and culture psychology, the cultural connotations of the English and Chinese color words differ greatly, as a result, these particular cultural connotation meanings are cast under different environments by different nationalities. There are a lot of similarities and differences on the meaning between English and Chinese color words. This paper analyzing Chinese and English color terms in the angle of lexicology, is guided by the book An Introduction to English Lexicology. After reviewing the research done by some linguists, this paper starts from the definition and origin of color terms, studies the changing and word-formation of color terms, then ends with some researches on the idioms on color terms, which gives a systematically comparison of Chinese and English color terms on their developing progress.
文摘Culture is the soul of a nation, and also the basis of landscape design, the basis of historical inheritance and innovation. Japanese garden was born out of Chinese garden, but because of the difference of geographical environment and national culture, Japanese gardens combine Chinese culture with local national characteristics, forming a unique garden culture in Japan. Based on the research on Japanese gardens like pond garden, rock garden and tea garden, this study analyzed the cultural connotation in Japanese garden landscape design, made in-depth understanding of Japanese landscape development, explored the value existing in the contemporary garden design of Japanese gardens, with the aim to make use of the excellent experience to the garden landscape design in the future.
文摘Yunnan is one of the most important homes habitations for the Yi nationality of China. As one of the ethnic minorities in China, the costume of the Yi nationality is of important research value. In this paper, the author emphatically analyzes the making process and cultural connotation of the Yi nationality＇s costume, and also proposes the problems and solutions in the inheritance and innovation of the Yi nationality＇s costume.
基金Project(51308548)supported by the National Natural Science Foundation of ChinaProject(2014M552155)supported by China Postdoctoral Science FoundationProject(2013RS4054)supported by the Science and Technology Fund of Hunan Province,China
文摘Thermal performance of envelopes and indoor thermal environment were technologically improved for traditional wooden vernacular dwellings of Tujia Minority in Western Hunan, China, on the premise of protecting their conventional styles. Thermal insulation boards and wooden boards were added to the interior side of external walls of vernacular dwellings to form two layers of air cavities, so as to gain excellent thermal performance. The indoor temperature of such dwellings after reconstruction was apparently improved compared with the data before reconstruction both in winter and summer, which verified the feasibility and the effectiveness of the reconstruction technologies proposed.
文摘The paper focuses on the connotation of ethnic culture elements of college English education for Three Minority Nations in Inner Mongolia and comprehensive and scientific explanation for Three Minority Nations. Corresponding solutions were proposed from the aspects of teachers, teaching materials, curriculum and so on and feasible suggestions were put forward for nationality culture building by the English education of Three Minority Nations in Inner Mongolia on this basis.
基金This paper is Supported by the Youth Science Foundation of Henan University of Science and Technology （Grant No. 2104SQN020）
文摘Chinese classical dance contains a profound connotation of Chinese traditional culture, with distinctive forms of performance and aesthetic characteristics. In the world of multi-cultttral communion, the development of Chinese classical dance needs to be inherited on the basis of traditional culture to inject more innovation, highlight its unique artistic aesthetic value and deep national culture contains. In this paper, the development course, aesthetic characteristics and classical dance form of Chinese classical dance are expounded. From the perspectives of historical cultural inheritance, classical dance culture cultivation and dance culture innovation, the feasibility measures and measures are put forward in order to explore the effective path and methods to developing Chinese classical dance, which gives excellent national dance art inheritance, development and innovation.
基金Supported by National Natural Science Foundation of China:81173327/H2718
文摘Objective To comparatively observe the effect of electroacupuncture at digestive system-related lower he-sea points on the expressions of serum interleukin-1β（IL-1 β）, tumor necrosis factor-α（TNF-α） of colon tissues and high mobility group box 1 protein（HMGB 1） of ulcerative colitis（UC） model rats, and to explore whether there is relative specificity of electroacupuncture at Shàngjùxū（上巨虚 ST 37）, one of lower he-sea points of large intestine, in treatment of bowel diseases. Method A total of 60 SD rats were randomly divided into control group, model group, ST 37 group, Zúsānl？（足三里 ST 36） group, Xiàjùxū（下巨虚 ST 39） group and Yánglíngquán（阳陵泉 GB 34） group. There were ten rats in each group; five were males, and five were females. UC models were established by clysis with 2, 4, 6-trinitrobenzene sulfonic acid/alcohol solution. After modeling, treatment was conducted for ten days, specimens were collected, colonic ulcers and inflammation were inspected visually and scored. The content of serum IL-1β and the expressions of TNF-α and HMGB 1 in colon were detected through ELISA. Results 1 Compared with control group, the scores of colonic ulcers and inflammation, the content of serum IL-1β and the expressions of TNF-α（except ST 37 group） and HMGB 1 were all higher（P〈0.05, P〈0.01）; 2 compared with model group, the scores of colonic ulcers in ST 36 group and ST 37 group were lower obviously（P〈0.05, P〈0.01）; the expressions of IL-1β, TNF-α and HMGB 1 in the four treatment groups were lower obviously（P〈0.01）; 3 compared with ST 37 group, the expressions of IL-1β, TNF-α and HMGB 1 in other three treatment groups were higher obviously（P〈0.05, P〈0.01）; and the scores of colonic ulcers in ST 39 group and GB 34 group were higher obviously（P〈0.05）. Conclusion 1 The score of colonic ulcers can be reduced through electroacupuncture at ST 37, ST 36, ST 39 and GB 34, which can also reduce the content of serum IL-1β and the expressions of TNF-α and HMGB 1, and effectively inhibit inflammatory response of colon caused by UC; 2 the effect trend of the four acupoints in treatment of UC is： ST 37ST 36ST 39GB 34, and electroacupuncture at ST 37 has the best effect with relative specificity.
文摘Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity.In this review we discuss the roles of the Eph receptors in lens biology and cataract development.
