基于内流动力学的海洋输油柔性立管鲁棒边界控制

海洋输油柔性立管的振动是引起立管疲劳破坏的主要原因,对其研究边界控制是消除振动疲劳、减少断裂的有效方法.本文引入内流动力学,完善了立管原始无穷维分布参数模型,更好地表达了柔性立管的动力学响应.为抑制柔性立管在内外流激励下的振动奠下基础,本文用Lyapunov直接法对柔性立管系统的稳定性和状态一致有界性进行了证明,设计了边界控制器调节柔性立管的振动,其中控制器使用了符号函数来消除不确定性环境扰动对振动控制效果的影响,提高了系统的鲁棒性.仿真实验表明本文所设计的控制算法有效地减少了柔性立管的振动偏移量.

基于时变内流的柔性立管自适应边界控制

针对具有系统结构参数不确定的海洋柔性立管不确定性系统,为了提高其振动控制效果和品质,通过对立管结构参数进行估计,采用自适应控制技术和Lyapunov综合法,设计了自适应边界控制算法对耦合内流动力学的立管振动进行控制.所设计的自适应控制器能补偿系统参数不确定性,以及避免了控制溢出,并能保证系统的稳定性和一致有界性.仿真结果进一步验证了该控制算法对抑制立管振动的有效性.

海洋柔性立管输出反馈边界控制

针对耦合内流动力学的海洋柔性立管系统,为了提高其振动控制品质,结合Lyapunov直接法和高增益观测器理论设计了输出反馈边界控制和干扰观测器,用以抑制结构振动偏移量和减弱外部环境干扰载荷的影响.其后,证明了闭环系统解的存在性、唯一性和收敛性及闭环状态的一致有界性.此外,本文的控制设计和稳定性分析是基于立管的原始无穷维动力学进行的,因此关于模型截断法产生的控制溢出问题将不会产生.最后仿真结果验证了本文所提出的输出反馈边界控制器能有效抑制柔性立管的振动.

Effects of Different Draft Baffles on the Hydrodynamics in Internal-Loop Airlift Reactors

In this paper, a 2-D airlift reactor was developed. The streamline and hydrodynamic parameters were measured in a 2-D airlift loop reactor(ALR)with different draft baffles. Three regimes were observed under different conditions. Particle image velocimetry(PIV)measurement showed that the liquid velocity distribution in horizontal direction presented different profiles in the three regimes. The length, the height and the spacing of draft baffles were applied in the experiments to optimize the ALR structure. It was found that the draft tube structure is of great importance in determining the hydrodynamics of ALRs. Additionally, the experimental results may serve as a step to the further optimization and design of ALR.

The Ejffect of Vertical Internal Baffles on Fluidization Hydrodynamics and Grain Drying Characteristics

The effect of vertical internal baffles on the particle mixing and graindrying characteristics in a batch fluidized bed column is investigated. Experimental work wascarried out in a 3m high rectangular fluidized bed dryer of cross sectional area of 0.15 m x 0.61 mat different operating conditions using paddy, a group D particle, as the fluidizing material. Theresults of the study showed that the fluidized bed dryer system with vertical internal baffles gavebetter particle mixing effect in the bed of particles than that without vertical internal baffles.This is due to the fact that the vertical internal baffle act as gas bubble breakers by breaking upthe large gas bubbles into smaller ones. The smaller bubbles cause a more vigorous mixing in the bedof particles before finally erupting at the bed surface. This improves the contacting efficiencyand enhanced the heat and mass transfer of the fluidized bed system. Thus a higher drying rate wasobtained in the falling rate period because the higher contacting efficiency increases theevaporation rate at the particle surface. However, the drying rate in the diffusion region showslittle improvement because the moisture diffusivity does not depend on the contacting efficiency.The fluidized bed dryer with vertical internal baffles could therefore be used in the initial rapiddrying stage in a two stage drying strategy for paddy. The insertion of vertical internal bafflesinto a fluidized bed system improves the processing of Group D particles in a fluidized bed systemespecially if the system is large in scale.

Self-organized Criticality Model for Ocean Internal Waves

In this paper, we present a simple spring-block model for ocean internal waves based on the self-organized criticality （SOC）. The oscillations of the water blocks in the model display power-law behavior with an exponent of -2 in the frequency domain, which is similar to the current and sea water temperature spectra in the actual ocean and the universal Garrett and Munk deep ocean internal wave model [Geophysical Fluid Dynamics 2 （1972） 225; J. Geophys. Res. 80 （1975） 291]. The influence of the ratio of the driving force to the spring coefficient to SOC behaviors in the model is also discussed.

Hydrodynamics and Solids Mixing Behavior in a Riser with Blunt Internals

The hydrodynamics and solids mixing behavior in a riser with blunt internals are studied. A uniform radial distribution for solids fraction and particle velocity achieves near the internals. The turbulent velocity of particles near the wall increases with the addition of the internals, with the lateral solids mixing enhanced significantly. Probability density distribution of particle velocity is bimodal in the riser with internals, which is similar to that in the conventional riser, indicating that no significant difference in the micro flow structure exists between the riser with internals and the conventional riser. At the same time, the axial solids mixing behavior changes insignificantly with the addition of internals. These results indicate that the micro flow structure in the riser is very stable, which changes insignificantly with the change of the bed structure.

Ankaferd hemostat in the management of gastrointestinal hemorrhages

Gastrointestinal (GI) bleeding refers to any hemorrhage ascribed to the pathologies of the gastrointestinal tract,extending from the mouth to the anal canal.Despite the recent improvements in the endoscopic,hemostatic and adjuvant pharmacologic techniques,the reported mortality is still around 5%-10% for peptic ulcer bleeding and about 15%-20% for variceal hemorrhages.Although endoscopic management reduces the rates of re-bleeding,surgery,and mortality in active bleeding;early recurrence ratios still occur in around 20% of the cases even with effective initial hemostatic measures.In this quest for an alternative pro-hemostatic agent for the management of GI bleedings,Ankaferd blood stopper (ABS) offers a successful candidate,specifically for "difficult-to-manage" situations as evidenced by data presented in several studies.ABS is a standardized mixture of the plants Thymus vulgaris,Glycyrrhiza glabra,Vitis vinifera,Alpinia officinarum,and Urtica dioica.It is effective in both bleeding individuals with normal hemostatic parameters and in patients with deficient primary and/or secondary hemostasis.ABS also modulates the cellular apoptotic responses to hemorrhagic stress,as well as hemostatic hemodynamic activity.Through its effects on the endothelium,blood cells,angiogenesis,cellular proliferation,vascular dynamics,and wound healing,ABS is now becoming an effective alternative hemostatic medicine for gastrointestinal bleedings that are resistant to conventional anti-hemorrhagic measurements.The aim of this review is to outline current literature experience suggesting the place of ABS in the management of GI bleeding,and potential future controlled trials in this complicated field.

Clinical analysis of propofol deep sedation for 1,104 patients undergoing gastrointestinal endoscopic procedures:A three year prospective study

AIM： To analyze the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. METHODS： In this prospective study, conducted over a period of three years, 1,104 patients referred for a same day GI endoscopy procedure were analyzed. All patients were given a propofol bolus （0.5-1.5 mg/kg）. Arterial blood pressure （BP） was monitored at 3 rain intervals and heart rate and oxygen saturation （SpO2） were recorded continuously by pulse oximetry. Analyzed data acquisition was carried out before, during, and after the procedure. RESULTS： A statistically significant reduction in mean arterial pressure was demonstrated （P〈0.001） when compared to pre-intervention values, but severe hypotension, defined as a systolic blood pressure below 60mmHg, was noted in only 5 patients （0.5%）. Oxygen saturation decreased from 96.5% to 94.4 % （P〈0.001）. A critical decrease in oxygen saturation （〈90%） was documented in 27 patients （2.4%）. CONCLUSION： Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant hemodynamic side effelts if carefully titrated. All the patients （and especially ASA Ⅲ group） require monitoring and care of an anesthesiologist.

DYNAMIC CHANGES OF SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVELS IN A RAT MYOCARDIAL INFARCTION MODEL

To investigate the dynamic changes of serum vascular endothelial growth factor(VEGF) levels in a rat model of acute myocardial infarction. Materials and methods.Eighty eight adult male Sprague Dawley rats weighing approximately 270 g were used in this study. Eighty rats were subjected to left coronary artery ligation, with 8 rats for each different duration of infarct. Eight sham operated animals in which the left coronary artery was surgically exposed without ligation were used as controls. Blood samples were drawn from the right atrium before (sham animals) and 1,3,6,12,24 h and 2,3,5,7,14 d after myocardial infarction. The concentrations of serum VEGF were measured by a sensitive enzyme linked immunosorbent assay with a rabbit polyclonal antibody specific for VEGF. Results. In the 8 control animals, the mean concentration of serum VEGF was 66.99±17.83 pg/ml. Six hours after myocardial infarction, the level of serum VEGF significantly increased to 125.68±28.07 pg/ml (P<0.01 vs. sham controls), and reached a peak (240.61±70.63 pg/ml. P<0.01 vs. sham animals) at 24 h after ligation and then decreased gradually over the remaining 2 weeks. However, the level remained significantly elevated for 14 d (107.64±30.13pg/ml, P<0.01 vs. sham controls). Conclusion. The present study shows that the levels of serum VEGF are markedly increased until 14 d in the rat model of acute myocardial infarction. The increased serum VEGF level may play an important role in the angiogenesis associated with myocardial infarction.

Coupled simulation of BES-CFD and performance assessment of energy recovery ventilation system for office model

Thermal comfort and indoor air quality as well as the energy efficiency have been recognized as essential parts of sustainable building assessment. This work aims to analyze the energy conservation of the heat recovery ventilator and to investigate the effect of the air supply arrangement. Three types of mixing ventilation are chosen for the analysis of coupling ANSYS/FLUENT （a computational fluid dynamics （CFD） program） with TRNSYS （a building energy simulation （BES） software）. The adoption of mutual complementary boundary conditions for CFD and BES provides more accurate and complete information of indoor air distribution and thermal performance in buildings. A typical office-space situated in a middle storey is chosen for the analysis. The office-space is equipped with air-conditioners on the ceiling. A heat recovery ventilation system directly supplies flesh air to the office space. Its thermal performance and indoor air distribution predicted by the coupled method are compared under three types of ventilation system. When the supply and return openings for ventilation are arranged on the ceiling, there is no critical difference between the predictions of the coupled method and BES on the energy consumption of HVAC because PID control is adopted for the supply air temperature of the occupied zone. On the other hand, approximately 21% discrepancy for the heat recovery estimation in the maximum between the simulated results of coupled method and BES-only can be obviously found in the floor air supply ventilation case. The discrepancy emphasizes the necessity of coupling CFD with BES when vertical air temperature gradient exists. Our future target is to estimate the optimum design of heat recovery ventilation system to control CO2 concentration by adjusting flow rate of flesh air.

The Research on Optimization of the Multiphase Flow Field of Biogas Plant by Using CFD Software

The inner flow field of a biogas plant can be optimized by agitating the feedstock to be evenly distributed for a rising biogas production rate. A hydraulic agitator can be installed in the digester with outlets far above the bottom. Hydraulic mixing is essential in a solid-liquid two-phase flow process, in which large solid particles can be found at the initial stage and turn to being high-concentration viscous liquid （non-Newtonian fluid）. A 0.75 m3 digester was taken as a case study with CFD （computational fluid dynamics） software. The basic pattern was simulated by using water as the medium and the pattern of pseudo plastic fluid state was simulated by the Euler-Euler Model, then the effect of optimized design with bottom inflow and high dispersed outlets could be verified. Viewed from the mixing effects, the velocity of 0.6 m/s is better than l m/s for water medium, while 1 m/s better than 0.6 m/s for pseudo plastic fluid medium.

Phosphorothioate oligonucleotide inhibits tissue factor expression in endothelial cells induced by blood flow shear stress in rats

Objective： To determine the effect of antiparallel phosphorothioate triplex-forming oligonucleotide （apsTFO）, which was designed according to shear stress response element （SSRE） in tissue factor （TF） gene promoter region, on the expression of endothelial TF in carotid artery stenosis rats. Methods： Rat model of severe carotid artery stenosis were inflicted by silica gel tube ligation. Half an hour before the model infliction, GT20-apsTFO, GT20-psTFO and GT21-apsTFO labeled with green fluorescence （FITC） were injected into the vena caudalis of rat at a dose of 0.5 mg/kg. Half an hour, 4 or 9 h after the ligation, the distribution of TFO in the common carotid artery, the liver and the kidney was detected with aid of fluorescence microscopy. And the mRNA and protein expressions of TF, Egr-1 and Spl in the above-mentioned organs were determined with in situ hybridization and immunohistochemical assay respectively in 6 h after the model establishment, and the results were analyzed with an image analysis system. Results： Only in 1 h after TFO injection, fluorescent granules appeared in the liver, the kidney and the vascular wall and lumen of carotid artery, and then in 4.5 h, they still deposited in above sites except the vascular lumen. GT20-apsTFO and GT21-apsTFO significant down-regulated the mRNA and protein expressions of TF compared to the rats without treatment （P〈0.05）, and the former apsTFO had a more stronger effect than the later （P〈0.05）. GT20-psTFO had no such effect （P〉0.05）. The 3 TFOs had no inhibition on the mRNA and protein expressions of Egr-1 and Spl. Conclusion： Pretreated apsTFO can partly come into the vascular endothelial cells, and inhibit TF expression induced by shear stress, but had no effect on Egr-1 and Spl gene expressions.

Effect of floor level slit exhaust ventilation system on distribution of house dust

Based on the fact that the house dust usually falls on the ground, the floor level slit exhaust ventilation system including inlet located at the ceiling and outlet of slit exhaust installed at comer between wall and floor was considered. Experiments and simulations were performed to investigate the flow and diffusion fields that are affected by this floor level slit exhaust ventilation system. The characteristics of airflow with experiments and computation fluid dynamics （CFD） are generally similar except airflow at the location of impinging flow and the location right below the inlet. Riboflavin particles were used as the house dust. For the spatial distribution of riboflavin particles in the ventilation system before operation, due to the influence of gravity, different sizes of particles show smooth decay curve. After floor level slit exhaust ventilation system is operated, the decay rate of the particles becomes faster than that after the ventilation system is powered on, and the particles with diameter of 0.5-3.0 μm in the experimental data and calculated values show good agreement.

DNS analysis of incipient drop impact dynamics using an accurate level set method

A series of 2D direct numerical simulations were performed with an accurate level set method for single drop impacts.The adopted ACLS method was validated to be efficient with perfect mass conservation in both normal and oblique impacts.A square-root correction for neck bases was modified in accuracy as well as scope of applications.In addition,process of jet formation and evolution was studied to reveal internal dynamics in drop impacts.It's found that pressure gradient and vortex are coexisting and completive reasons for jet topology while the inclined angle has a significant effect on them.Mechanisms of jet formation and evolution are different in the front and back necks.With the help of PDF distribution and correction calculation,a compromise in the competition is observed.This work lays a solid foundation for further studies of dynamics in gas-liquid flows.

CFD Simulation of Reactor Internal Flow in the Scaled APR＋

A series of 1/5 scale reactor flow model tests have been conducted in order to determine the hydraulic characteristics of the APR＋ （advanced power reactor plus）. The objective of test was to determine the core inlet flow field of the model reactor in order to provide input information required by the open core thermal margin analysis code such as TORC. In this study, in order to examine the validity of the results of reactor flow model tests and the applicability of CFD （computational fluid dynamics） in the simulation of reactor internal flow, CFD simulation was conducted with the commercial multi-purpose CFD software, ANSYSCFX V. 14. It was found that the velocity field in the downcomer had the inhomogeneous feature. Relative high velocity region was located in the core region. This result was different from measurement and this difference may result from the fact that some internal structures were not modeled with the real geometry but treated as the porous domain.

Parameter identification of internal wave and mesoscale eddy

A simplified parameter identification algorithm for the inverse refractive indexes of the mesoscale eddy and the internal wave in the ocean is proposed by researching into the incident field and the scattered field that comprise the total field of a wave in the ocean, considering that the total field and the incident field satisfy the Helmholtz equations and the scattered field conforms to the Sommerfield radiation condition. Two examples for the calculation of refractive index and inverse refractive index respectively of the mesoscale eddy and the internal wave demonstrate the applicability of the algorithm.

Introduction to the Turbulent Flows Theory--An Axially-Symmetric Non-peaceful Flows

In fluid mechanics, there is lack of turbulent flows theory. The theory of laminar flows is also not completed. Therefore, the aim of this paper is to fill in the gaps in the theory of laminar flow. First time in the history of fluid mechanics, it shows that the value of the boundary Reynolds number, dividing the flows of Newtonian fluids into laminar and turbulent, can be calculated theoretically. The very existence of this boundary has been known to researchers over a century ago, but all knowledge in this area so far comes only from experimental physics. This paper marks a turning point, as it not only explains the theory of the said phenomenon, but also presents the methodology of its analytical description. It should be noted that the said description refers to the type of flow which is best understood by scientists, i.e., steady axially-symmetric laminar flow through a straight-axis duct of a circular cross-section of the radius R under the action of constant natural gravitational forces. This paper comes second in a series of papers aimed at eliminating chaos from fluid mechanics and replacing it with harmony and mathematical order.

Performance and Internal Flow of a Counter-rotating Type Tidal Stream Turbine

In the past decade, the tidal energies have caused worldwide concern as it can provide regular and predictable re- newable energy resource for power generation. The majority of technologies for exploiting the tidal stream energy are based on the concept of the horizontal axis propellers, which can be derived from the design and operation of wind turbines. However, there are some peculiar features such as the propeller working in the seawater with free surface and the possible occurrence of cavitation as compared with wind turbines. Especially, for a coun- ter-rotating type tidal stream power turbine, it is difficult to accurately predict the interaction between the front and rear blades at the design stage by blade element momentum theory. As a result, CFD shows its advantage to predict the performance of counter-rotating type propellers of the tidal stream turbi^le. In order to improve the accuracy of CFD predictions, the predicted results must be verified with experimental values. In this paper, a CFD model using block-structured grid was set up and experimental test was performed in a water tunnel for a tidal stream turbine with counter-rotating type propellers. The comparison between CFD predictions and experimental data shows quite good agreement on the power coefficients, which provides an evidence of validation of the CFD model. Such results offer the necessary confidence in the accuracy of the set up CFD model for the coun- ter-rotating type tidal stream turbine.

On Problems with Downscaling in Internal Flows

Problems that may accompany downscaling in internal flows are discussed. Non-dimensional similarity parameters （like Re, M, etc.） depend on parameters that scale down fully （e.g., length）, or that are specified by design （velocities, cascade geometry）, or that are scale invariant （like thermophysical and transport properties of fluids）.This fact has to be taken into acount in the similarity considerations. With decreasing Reynolds number the surface forces become of growing importance, however, if not going down directly to microflows the main problems are connected with the three-dimensional flow structure affecting the skin friction, and with the fact that some of the flow phenomena （e.g. vortical structures） cannot fully develop.