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一种新型内粘膜编织袋
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作者 王仁龙(整理) 《塑料包装》 CAS 2020年第3期62-64,共3页
本文介绍了一种新型内粘膜编织袋,包括防潮袋,所述防潮袋表面中心位置固定连接有编号栏,所述编号栏表面覆盖一层透明橡胶垫,所述防潮袋背面固定连接有两根背带,所述防潮袋表面固定连接有两个对称设置的第一橡胶防滑垫,所述防潮袋背面固... 本文介绍了一种新型内粘膜编织袋,包括防潮袋,所述防潮袋表面中心位置固定连接有编号栏,所述编号栏表面覆盖一层透明橡胶垫,所述防潮袋背面固定连接有两根背带,所述防潮袋表面固定连接有两个对称设置的第一橡胶防滑垫,所述防潮袋背面固定连接有呈工字形设置的第二橡胶防滑垫。该装置方便清洁设备,机械精度高,提高了生产效率,也提高了产品质量,且操作简单,生产成本低。该编织袋可以有效的保护带内的物品不被高温、火灾,水灾侵害,也可以有效地对货物进行分类和定位,也可以避免该编织袋在堆积后滑落。 展开更多
关键词 编织袋 新型 内粘膜 防潮
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改良Buess技术内镜腔内粘膜切除治疗早期胃癌的远期效果
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作者 汪志明 《国外医学(外科学分册)》 2003年第6期371-371,共1页
关键词 改良Buess技术 内镜 内粘膜切除 治疗 胃癌 远期效果
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膀胱内粘膜沟固定法增强缩窄回肠控制的实验研究
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作者 徐月敏 乔勇 +4 位作者 撒应龙 张炯 张心如 李涛 陈忠 《中华实验外科杂志》 CAS CSCD 北大核心 2001年第5期393-393,共1页
关键词 膀胱内粘膜沟固定法 缩窄回肠 控制机制
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慢性鼻窦炎治疗的研究 被引量:6
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作者 牛良君 向涛 《中国实用医药》 2009年第26期95-95,共1页
关键词 慢性鼻窦炎 一般治疗 中西医结合治疗 渗出性炎症 常见疾病 耳鼻咽喉科 鼻窦内粘膜 反复发作
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经口内黏膜入路切除口周皮脂腺囊肿临床应用 被引量:1
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作者 王立鹏 扈容英 +3 位作者 田甜 王媛 焦亚宁 刘昱昕 《宁夏医科大学学报》 2021年第1期89-91,共3页
目的探讨经口腔内黏膜入路切除口周皮脂腺囊肿的临床疗效。方法选取2017年1月至2019年5月就诊于宁夏医科大学总医院皮肤科门诊经口腔内黏膜入路切除口周皮脂腺囊肿患者46例,术后随访1~2个月。结果 46例患者手术切口均一期愈合,无复发。... 目的探讨经口腔内黏膜入路切除口周皮脂腺囊肿的临床疗效。方法选取2017年1月至2019年5月就诊于宁夏医科大学总医院皮肤科门诊经口腔内黏膜入路切除口周皮脂腺囊肿患者46例,术后随访1~2个月。结果 46例患者手术切口均一期愈合,无复发。结论经口腔内黏膜入路切除口周皮脂腺囊肿,术后无复发、美容效果明显,值得推广应用。 展开更多
关键词 口周 皮脂腺囊肿 口腔内粘膜 美容效果
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三联疗法治疗慢性鼻窦炎
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作者 李惠兰 《海南医学》 CAS 2001年第6期94-95,共2页
关键词 三联疗法 慢性鼻窦炎 上颌窦穿刺 鼻窦内粘膜 林可霉素 灭滴灵
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Alterations of intestinal mucosa structure and barrier function following traumatic brain injury in rats 被引量:37
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作者 Chun-HuaHang Ji-XinShi +2 位作者 Jie-ShouLi WeiWu Hong-XiaYin 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第12期2776-2781,共6页
AIM: Gastrointestinal dysfunction is a common complication in patients with traumatic brain injury (TBI). However, the effect of traumatic brain injury on intestinal mucosa has not been studied previously. The aim of ... AIM: Gastrointestinal dysfunction is a common complication in patients with traumatic brain injury (TBI). However, the effect of traumatic brain injury on intestinal mucosa has not been studied previously. The aim of the current study was to explore the alterations of intestinal mucosa morphology and barrier function, and to determine how rapidly the impairment of gut barrier function occurs and how long it persists following traumatic brain injury.METHODS: Male Wistar rats were randomly divided into six groups (6 rats each group) including controls without brain injury and traumatic brain injury groups at hours 3,12, 24, and 72, and on day 7. The intestinal mucosa structure was detected by histopathological examination and electron microscopy. Gut barrier dysfunction was evaluated by detecting serum endotoxin and intestinal permeability. The level of serum endotoxin and intestinal permeability was measured by using chromogenic limulus amebocyte lysate and lactulose/mannitol (L/M) ratio, respectively.RESULTS: After traumatic brain injury, the histopathological alterations of gut mucosa occurred rapidly as early as 3 hours and progressed to a serious state, including shedding of epithelial cells, fracture of villi, focal ulcer, fusion of adjacent villi, dilation of central chyle duct, mucosal atrophy,and vascular dilation, congestion and edema in the villous interstitium and lamina propria. Apoptosis of epithelial cells,fracture and sparseness of microvilli, loss of tight junction between enterocytes, damage of mitochondria and endoplasm, were found by electron microscopy. The villous height, crypt depth and surface area in jejunum decreased progressively with the time of brain injury. As compared with that of control group (183.7±41.8 EU/L), serum endotoxin level was signnificantly increased at 3, 12, and 24 hours following TBI (434.8±54.9 EU/L, 324.2±61.7 EU/L and 303.3±60.2 EU/L, respectively), and peaked at 72 hours (560.5±76.2 EU/L), then declined on day 7 (306.7±62.4 EU/L,P<0.0L). Two peaks of serum endotoxin level were found at hours 3 and 72 following TBI. L/M ratio was also significantly higher in TBI groups than that in control group (control,0.0172±0.0009; 12 h, 0.0303±0.0013; 24 h, 0.0354±0.0025;72 h, 0.0736±0.0105; 7 d, 0.0588±0.0083; P<0.01).CONCLUSION: Traumatic brain injury can induce significant damages of gut structure and impairment of barrier function which occur rapidly as early as 3 hours following brain injury and lasts for more than 7 days with marked mucosal atrophy. 展开更多
关键词 创伤性脑损伤 内粘膜 肠内屏障 胃肠道功能失调 动物实验
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Review The Recent Studies on Treatment of the Damaged Intestinal Mucosa 被引量:1
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作者 陈艳芬 陈蔚文 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第4期299-304,共6页
Intestinal mucosa serves as an important defencebarrier of the organism because the damaged mucosamay cause a variety of pathogenic changes.
关键词 内粘膜损害 中医药疗法 研究进展 免疫调节 微循环 组织修复
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PPH加Block术与单纯Block术治疗直肠前突的临床比较研究
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作者 万林 《中外女性健康研究》 2016年第2期45-45,29,共2页
目的:对比观察单纯直肠闭式修补术(Block)与吻合器痔上黏膜环切术(PPH术)联合Block术治疗直肠前突的临床效果。方法:收集我院自2013年12月至2014年12月期间收治的110例直肠前突患者的临床资料,根据手术方案的不同将110例患者分为观察组(... 目的:对比观察单纯直肠闭式修补术(Block)与吻合器痔上黏膜环切术(PPH术)联合Block术治疗直肠前突的临床效果。方法:收集我院自2013年12月至2014年12月期间收治的110例直肠前突患者的临床资料,根据手术方案的不同将110例患者分为观察组(n=62)和对照组(n=48),对照组采用单纯Block术治疗,观察组采用PPH术加Block术,观察两组患者治疗有效率、术后并发症发生率等指标,并行统计学对比。结果:两组患者术后并发症均发生2例,发生率接近,无统计学意义(P<0.05),治疗有效率比较观察组占优,差异显著,存在统计学意义(P<0.05)。结论:PPH术联合Block术治疗直肠前突更符合解剖学复位的手术要求,治疗有效率高,值得临床推广应用。 展开更多
关键词 直肠前突 直肠内粘膜环切术 直肠闭式修补术
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71型肠病毒脑脊髓炎(Enterovirus 71 encephalomyelitis)
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作者 胡宜 《日本医学介绍》 2004年第2期95-96,共2页
关键词 肠病毒脑脊髓炎 发热性疾病 口腔内粘膜 四肢皮肤水泡
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Quantitative ultrastucture analysis of neuroendocrine cells of gastric mucosa on normal and pathological conditions
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作者 虞积耀 D'Adda T 《World Journal of Gastroenterology》 SCIE CAS CSCD 1996年第3期155-157,共3页
AIMS To study the quantitative ultrastucture of neu- roendocrine cells of gastric mucosa on normal anc pathological conditions including the duodenal ulcer (DU) and Zollinger-Ellison syndrome (ZES). METHODS The neuroe... AIMS To study the quantitative ultrastucture of neu- roendocrine cells of gastric mucosa on normal anc pathological conditions including the duodenal ulcer (DU) and Zollinger-Ellison syndrome (ZES). METHODS The neuroendocrine cells of the gastric mucosa of eight normal subjects,six patients with DU and five patients with ZES were quantitatively investi- gated with electro microscope and ultrastructure image analyzer. RESULTS The volume density of neuroendocrine cells in DU was 1.3% and 0.8% (vs 1.6% and 0.9%,P>0.05) in gastric antrum and corpus respectively. In antrum,G cells was of 65% (P< 0.05),D cells decreased in cell density (3% vs 9.5%) and in number of cell per unit area (P<0.01). In corpus,the cell density of ECL cells increased (49% vs 30%,P<0.05);D cells and EC cells decreasec (2% P<0.01 and 4% P<0.05,respectively),and the number of D cell per unit area markedly decreased. In ZES,D cells in corpus decreased in cell density (4% vs 22%,P<0.01) and P cells also decreased (11% vs 24%,P<0.05). The density of ECL cells increased (65% vs 30%,P<0.01). CONCLUSIONS In DU and ZES,both the number and type of NE cells present some changes. Incresed gastrin in DU and ZES patients may be caused by the decrease of D cells and somatostatin secretion. 展开更多
关键词 gastric mucosa/pathology neuroendocrine cells duodenal ulcer Zollinger-Ellison syndrome
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The antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo 被引量:4
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作者 史大永 李敬 +2 位作者 郭书举 苏华 范晓 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2009年第2期277-282,共6页
To investigate the antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo, six bromophenol derivatives 6-(2,3-dibromo-4,5-dihydroxybenzyl)-2,3-dibromo-4,5-dihydroxy benzyl methyl eth... To investigate the antitumor effect of bromophenol derivatives in vitro and Leathesia nana extract in vivo, six bromophenol derivatives 6-(2,3-dibromo-4,5-dihydroxybenzyl)-2,3-dibromo-4,5-dihydroxy benzyl methyl ether (1), (+)-3-(2,3-dibromo-4,5-dihydroxyphenyl)-4-bromo-5,6-dihydroxy-1,3- dihydroisobenzofuran (2), 3-bromo-4-(2,3-dibromo-4,5-dihydroxybenzyl)-5-methoxymethyl-pyrocatechol (3), 2,2',3,3'-tetrabromo-4,4',5,5'-tetrahydroxy-diphenylmethane (4), bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (5), 2,2',3-tribromo-3',4,4',5-tetrahydroxy-6'-ethyloxymethyldiphenylmethane (6) were isolated from brown alga Leathesia nana, and their cytotoxicity were tested by MTF assays in human cancer cell lines A549, BGC-823, MCF-7, B16-BL6, HT-1080, A2780, Be17402 and HCT-8. Their inhibitory activity against protein tyrosine kinase (PTK) with over-expression of c-kit was analyzed also by ELISA. The antitumor activity of ethanolic extraction of Leathesia nana (EELN) was evaluated on S180-bearing mice. All compounds showed very potent cytotoxicity against all of the eight cancer cell lines with IC50 below 10 pg/mL. In PTK inhibition study, all bromophenol derivatives showed moderate inhibitory activity and compounds 2, 5 and 6 showed significant bioactivity with the inhibition ratio of 77.5%, 80.1% and 71.4% respectively. Pharmacological studies reveal that EELN could inhibit the growth of Sarcoma 180 tumor and increase the indices of thymus and spleen to improve the immune system remarkably in vivo. Results indicated that the bromophenol derivatives and EELN can be used as potent antitumor agents for PTK over-expression of c-kit and considered in a new therapeutic strategy for treatment of cancer. 展开更多
关键词 Leathesia nana bromophenol derivatives ANTITUMOR in vitro in vivo
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Changes in intestinal mucosal immune barrier in rats with endotoxemia 被引量:35
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作者 Chong Liu Ang Li +3 位作者 Yi-Bing Weng Mei-Li Duan Bao-En Wang Shu-Wen Zhang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第46期5843-5850,共8页
AIM: To investigate the dysfunction of the immunological barrier of the intestinal mucosa during endotoxemia and to elucidate the potential mechanism of this dysfunction. METHODS: Male Wistar rats were randomly dist... AIM: To investigate the dysfunction of the immunological barrier of the intestinal mucosa during endotoxemia and to elucidate the potential mechanism of this dysfunction. METHODS: Male Wistar rats were randomly distributed into two groups: control group and lipopolysaccharide (LPS) group. Endotoxemia was induced by a single caudal venous injection of LPS. Animals were sacrificed in batches 2, 6, 12 and 24 h after LPS infusion. The number of microfold (M)-cells, dendritic cells (DCs), CD4+ T cells, CD8+ T cells, regulatory T (Tr) cells and IgA+ B cells in the intestinal mucosa were counted after immunohistochemical staining. Apoptotic lymphocytes were counted after TUNEL staining. The levels of interleukin (IL)-4, interferon (IFN)-γ, and forkhead box P3 (Foxp3) in mucosal homogenates were measured by ELISA. The secretory IgA (sIgA) content in the total protein of one milligram of small intestinal mucus was detected using a radioimmunological assay.RESULTS: This research demonstrated that LPS-induced endotoxemia results in small intestinal mucosa injury. The number of M-cells, DCs, CD8~ T cells, and IgA~ B cells were decreased while Tr cell and apoptotic lymphocyte numbers were increased significantly. The number of CD4+ T cells increased in the early stages and then slightly decreased by 24 h. The level of IL-4 significantly increased in the early stages and then reversed by the end of the study period. The level of IFN-T increased slightly in the early stages and then decreased markedly by the 24 h time point. Level of Foxp3 increased whereas sIgA level decreased.CONCLUSION: Mucosal immune dysfunction forms part of the intestinal barrier injury during endotoxemia. The increased number and function of Tr cells as well as lymphocyte apoptosis result in mucosal immunode- ficiency. 展开更多
关键词 ENDOTOXEMIA RATS Intestinal mucosa IMMUNITY
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Treatment of over 20 mm gastric cancer by endoscopic submucosal dissection using an insulation-tipped diathermic knife 被引量:14
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作者 Shoji Hirasaki Hiromitsu Kanzaki +5 位作者 Minoru Matsubara Kohei Fujita Fusao Ikeda Hideaki Taniguchi Eiichiro Yumoto Seiyuu Suzuki 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第29期3981-3984,共4页
AIM: To evaluate the effectiveness of endoscopic submucosal dissection using an insulation-tipped diathermic knife (IT-ESD) for the treatment of patients with over 20 mm early gastric cancer (EGC). METHODS: A to... AIM: To evaluate the effectiveness of endoscopic submucosal dissection using an insulation-tipped diathermic knife (IT-ESD) for the treatment of patients with over 20 mm early gastric cancer (EGC). METHODS: A total of 112 patients with over 10 mm EGC were treated with IT-ESD at Sumitomo Besshi Hospital and Shikoku Cancer Center in the 5 year period from January 2002 to December 2006, including 40 patients with over 20 mm EGC. We compared patient backgrounds, the one-piece resection rate, complete resection (CR) rate, operation time, bleeding rate, perforation rate between patients with over 20 mm EGC [over 20 mm group (21-40 ram)] and the remaining patients (under 20 mm group). RESULTS: We found no significant difference in the rate of underlying cardiopulmonary disease (over 20 mm group vs under 20 mm group, 5.0% vs 5.6%), one- piece resection rate (95% vs 96%), CR rate (85% vs 89%), operation time (72.3 rain vs 66.5 rain), bleeding rate (50 vs 4.2%), and perforation rate (0% vs 1.4%) between the 2 groups. Three patients in each group had submucosal invasion and two in each groups underwent additional surgery. CONCLUSION: There was no significant difference in the outcome resulting from IT-ESD between the 2 groups. Our study proves that IT-ESD is a feasible treatment for patients with over 20 mm mucosal gastric cancer although the long-term outcome should be evaluated in the future. 展开更多
关键词 Gastric cancer Endoscopic mucosal resection Insulation-tipped diathermic knife COMPLICATION
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Endoscopic mucosal resection in the upper gastrointestinal tract 被引量:9
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作者 Anis Ahmadi Peter Draganov 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第13期1984-1989,共6页
Endoscopic mucosal resection (EMR) is a technique used to locally excise lesions confined to the mucosa. Its main role is the treatment of advanced dysplasia and early gastrointestinal cancers. EMR was originally de... Endoscopic mucosal resection (EMR) is a technique used to locally excise lesions confined to the mucosa. Its main role is the treatment of advanced dysplasia and early gastrointestinal cancers. EMR was originally described as a therapy for early gastric cancer. Recently its use has expanded as a therapeutic option for ampullary masses, colorectal cancer, and large colorectal polyps. In the Western world, the predominant indication for EMR in the upper gastrointestinal tract is the staging and treatment of advance dysplasia and early neoplasia in Barrett's esophagus. This review will describe the basis, indications, techniques, and complications of EMR, and its role in the management of Barrett's esophagus. 展开更多
关键词 Endoscopic mucosal resection Mucosal resection Barrett's esophagus Barrett's dysplasia Therapeutic endoscopy
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Endoscopic diagnosis of Barrett's esophagus
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作者 Tomoyuki Akiyama Yusuke Sekino +5 位作者 Hiroshi Iida Shigeru Koyama Eiji Gotoh Shin Maeda Atsushi Nakajima Masahiko Inamori 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第26期3477-3478,共2页
The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus(BE).BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal mar... The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus(BE).BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal margin of the gastric folds.In this study,we reported that 43.0% of the subjects examined were diagnosed with BE based on the Prague C and M Criteria.Previous criticism by John Dent proposed that our data should be considered invalid because the prevalence of BE reported in our study was extraordinarily high and discordant with previous studies.Dent predicted that the position of the gastroesophageal junction in our study was judged to be lower than the actual position due to the effacement of the proximal ends of the gastric folds because of the routine use of a high degree of air distension during typical Japanese endoscopic examinations.The endoscopic evaluation of the superior gastric folds is certainly influenced by the degree of air distension of the esophagus.However,in our study,the proximal limit of the gastric mucosal folds was prospectively imaged while the oesophagus was minimally insufflated.Then,under a high level of air distension,the distal ends of the palisade-shaped longitudinal vessels were imaged because they are more easily observed when distended.In the majority of patients,the distal ends of the palisade-shaped longitudinal vessels correspond to the proximal limit of the gastric mucosal folds.Our endoscopic evaluation was appropriately performed according to the Prague C and M Criteria.We suspect that the high prevalence of BE in our study may be due to the inclusion of ultrashort-segment BE,which defines BE with an affected mucosal length under 5 mm,in our positive results. 展开更多
关键词 Barrett's esophagus Gastroesophagealjunction Squamocolumnar junction Digital endoscopicimages ENDOSCOPY
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Down stream involvement of the bile duct in hepatolithiasis 被引量:2
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作者 卢实春 严律南 +4 位作者 饶林强 夏天 苟剑林 张仕羽 雷松 《Chinese Medical Journal》 SCIE CAS CSCD 2002年第1期62-64,147,共3页
Objective To evaluate the down stream involvement of the bile duct in hepatolithiasis.Methods Mechanical damage to bile duct epithelia and long standing cholangitis as result of hepatolithiasis play an important rol... Objective To evaluate the down stream involvement of the bile duct in hepatolithiasis.Methods Mechanical damage to bile duct epithelia and long standing cholangitis as result of hepatolithiasis play an important role in the carcinogenesis of bile duct epithelia and stricture of the intra- and extra-hepatic bile duct. Macromorphological and microscopic changes in bile duct mucosa of 100 consecutive patients with hepatolithiasis were investigated using intra- or post-operative cholangioscopy. Biopsy specimens of lesions obtained during cholangioscopy were studied with immunohistochemical staining and flow cytometry to determine proliferative activity and DNA content. Five cases of well-proven cholangiocarcinoma were simultaneously studied as controls.Results Of the 100 patients, those with chronic cholangitis accounted for 86% (86/100), proliferative lesions 11% (11/100), adenomatous polyps 1% (1/100), and adenocarcinoma 2% (2/100). The obvious mucosal lesion associated with hepatolithiasis was located down-stream of the bile duct, predominantly in the hilar region, e.g. orifices of the right/left hepatic duct and common hepatic duct (73% mucosa lesions in the hilar region). The intensity of cancer embryonic antigen stain and the proliferative cell nuclear antigen index increased with the development of bile duct lesions. Aneuploid DNA presented mainly in the high degree malignant adenocarcinomas (】80% of cases).Conclusions The obvious mucosal lesions associated with hepatolithiasis were located down-stream of the bile duct, predominantly in the hilar region (73% of mucosal lesions). The proliferative activity of examined bile duct mucosa lesions increased with the development of pathological deterioration, which may contribute to the development of hilar bile duct stricture and hilar cholangiocarcinoma. 展开更多
关键词 hepatolithiasis · bile duct stricture · carcinogenesis · hilar region
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胃肠钡剂造影在当今胃肠检查中的价值
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作者 刘忠政 《医用放射技术杂志》 2006年第1期29-30,共2页
以硫酸钡作为造影剂来检查消化道疾病技术已有近一百年的历史。长期以来,它一直是临床对胃肠道疾病作出诊断的主要方法,并通过胃肠造影的间接征象来诊断胃肠道以外器官的占位性病变。随着胃结肠镜的应用,其钡剂造影检查总数,呈逐年... 以硫酸钡作为造影剂来检查消化道疾病技术已有近一百年的历史。长期以来,它一直是临床对胃肠道疾病作出诊断的主要方法,并通过胃肠造影的间接征象来诊断胃肠道以外器官的占位性病变。随着胃结肠镜的应用,其钡剂造影检查总数,呈逐年下降趋势。承认胃结肠镜可直接观察胃肠内粘膜变化,并摘取组织作病理检测。大大提高了粘膜表面细微病变的诊断,这就跟钡剂胃肠造影提出了挑战。怎样利用钡剂造影诊断粘膜的微小病变。60年代后期,日本学者在传统的钡剂造影的基础上,发展并创造了崭新的胃肠道双重对比。即气钡双重对比。80年代气钡双重对比在我国开展得很红火,经不少放射学专家的努力,此种造影结合低张对早期病变,浅表性粘膜糜烂,小的溃疡均能发现。故消化道钡剂造影又显示出强大的生命力。 展开更多
关键词 钡剂造影检查 胃肠道疾病 气钡双重对比 消化道钡剂造影 占位性病变 造影诊断 胃肠造影 内粘膜 消化道疾病
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