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内镜下黏膜消融术治疗食管黏膜高级别上皮内瘤变临床分析
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作者 吴大成 丁岩冰 +3 位作者 邓彬 孙建宏 陈海燕 赵烨 《胃肠病学和肝病学杂志》 CAS 2014年第9期1095-1097,共3页
目的探讨内镜下黏膜消融术(endoscopic mucosal ablation,EMA)治疗食管黏膜高级别上皮内瘤变(high grade intraepithelial neoplasia,HIN)的疗效和安全性。方法收集扬州市第一人民医院2010年7月-2012年6月经内镜检查发现的食管黏膜患者3... 目的探讨内镜下黏膜消融术(endoscopic mucosal ablation,EMA)治疗食管黏膜高级别上皮内瘤变(high grade intraepithelial neoplasia,HIN)的疗效和安全性。方法收集扬州市第一人民医院2010年7月-2012年6月经内镜检查发现的食管黏膜患者32例作为入选对象,术前行染色内镜和超声内镜检查,确定病变范围和深度,常规行术前评估,观察手术时间、手术成功率及并发症发生率,并进行术后随访。结果平均手术操作时间(21.6±2.8)min;手术成功率100%,术中及术后均无出血、穿孔发生。术后2例患者病理证实癌变,转为外科手术及放疗。术后随访率93.75%,随访患者中6个月内切面愈合率100%。结论 EMA治疗食管黏膜HIN安全性及有效性高,并发症少。 展开更多
关键词 内镜下黏膜消融术 高级别上皮内瘤变 随访
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Endoscopic resection of gastric and esophageal cancer 被引量:1
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作者 Bryan Balmadrid Joo Ha Hwang 《Gastroenterology Report》 SCIE EI 2015年第4期330-338,I0002,共10页
Endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)techniques have reduced the need for surgery in early esophageal and gastric cancers and thus has lessened morbidity and mortality in these dis... Endoscopic submucosal dissection(ESD)and endoscopic mucosal resection(EMR)techniques have reduced the need for surgery in early esophageal and gastric cancers and thus has lessened morbidity and mortality in these diseases.ESD is a relatively new technique in western countries and requires rigorous training to reproduce the proficiency of Asian countries,such as Korea and Japan,which have very high complete(en bloc)resection rates and low complication rates.EMR plays a valuable role in early esophageal cancers.ESD has shown better en bloc resection rates but it is easier to master and maintain proficiency in EMR;it also requires less procedural time.For early esophageal adenocarcinoma arising from Barrett’s,ESD and EMR techniques are usually combined with other ablative modalities,the most common being radiofrequency ablation because it has the largest dataset to prove its success.The EMR techniques have been used with some success in early gastric cancers but ESD is currently preferred for most of these lesions.ESD has the added advantage of resecting into the submucosa and thus allowing for endoscopic resection of more aggressive(deeper)early gastric cancer. 展开更多
关键词 endoscopic submucosal dissection endoscopic mucosal resection endoscopic ablation early gastric cancer early esophageal cancer
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