目的分析解放军306医院心脏中心急性ST段抬高型心肌梗死(STEMI)救治体系中不同性别患者之间再灌注时间延迟的分布。方法纳入2011年1月-2015年12月解放军306医院连续急诊收治并符合入选标准的STEMI患者325例,依据性别不同分为男性组(268...目的分析解放军306医院心脏中心急性ST段抬高型心肌梗死(STEMI)救治体系中不同性别患者之间再灌注时间延迟的分布。方法纳入2011年1月-2015年12月解放军306医院连续急诊收治并符合入选标准的STEMI患者325例,依据性别不同分为男性组(268例)和女性组(57例),分析各急救时间,包括发病(SO)至首次医疗接触(FMC)时间(SO-to-FMC)、转运时间(FMC-to-D)、FMC-to-B、导管室启动延迟时间、介入操作延迟时间、急诊至球囊扩张血管再通时间(D-to-B)等,并观察预后。结果尽管女性患者的院前延迟时间中位数(160.0min)和So-to-FMC中位数(100.0min)较男性(分别为119.5min和69.5min)延长,但差异无统计学意义,其余各项再灌注延迟时间差异也无统计学意义(P>0.05)。女性患者合并高血压、糖尿病者比例较高,吸烟率明显低于男性(P<0.05);两组STEMI患者30d内和1年内的主要心脑血管不良事件(MACCE)发生率(男性5.22% vs 女性5.26%;男性10.82% vs 女性8.77%)差异无统计学意义(P>0.05)。结论性别因素对再灌注延迟的影响正逐渐弱化。展开更多
Objective There are still a high proportion of patients with ST-segment elevation myocardial infarction （STEMI） missing out early reperfusion even in the primary percutaneous coronary intervention （PCI） era. Most ...Objective There are still a high proportion of patients with ST-segment elevation myocardial infarction （STEMI） missing out early reperfusion even in the primary percutaneous coronary intervention （PCI） era. Most of them are stable latecomers, but the optimal time to undergo delayed PCI for stable ones remains controversial. Methods We investigated all STEMI patients who underwent delayed PCI （2-28 days after STEMI） during 2007-2010 in Beijing and excluded patients with hemodynamic instability. The primary outcome was maj or adverse cardiovascular events （MACEs）. Results This study finally enrolled 5,417 STEMI patients and assigned them into three groups according to individual delayed time （Early group, 55.9%; Medium group, 35.4%; Late group, 8.7%）. During 1-year follow-up, MACEs occurred in 319 patients. The incidence of MACEs were respectively 7.1%, 5.6% and 6.7% among three groups. The Medium group had less recurrent myocardial infarction plus cardiac death （hazard ratio, 0.525; 95% confidence interval, 0.294-0.938, P = 0.030） than Late group and less repeat revascularization （hazard ratio, 0.640; 95% confidence interval, 0.463-0.883, P = 0.007） than Early group in pairwise comparisons. We depicted the incidence of major adverse cardiovascular event （MACE） by delayed time as a quadratic curve and found the bottom appeared at day 14. Conclusions The delayed PCI time varied in the real-world practice, but undergoing operations on the second week after STEMI had greater survival benefit and less adverse events for whom without early reperfusion and hemodynamic instability.展开更多
Rooting ability of indole 3-butyric acid （IBA）-induced stem cuttings in vegetative regeneration experiments depends on various parameters, which can be entrenched using sprouting value index （SVI）, a mathematical ...Rooting ability of indole 3-butyric acid （IBA）-induced stem cuttings in vegetative regeneration experiments depends on various parameters, which can be entrenched using sprouting value index （SVI）, a mathematical approach. In this study, field studies were carried out in Tabebuia rosea to generate clonal planting stock regeneration using three rooting medium at a location in Central Kerala, Peninsular India, for three consecutive years from October 2014 till June 2016 at four months regular intervals. Three IBA concentrations, viz., 200, 500 and 1,000 ppm, have been used and the data obtained was evaluated using SVI method in order to establish the suitable medium, which gives the maximum rooting results. Control cuttings did not record rooting in any of the trials. The high SVI was obtained when stem root cuttings planted in root trainers with coir pith compost （RTCP） for all the three concentration of IBA applied. Sprouting percentage was marked up and the delay in completion of sprouting/rooting initiation decreased by the use of IBA treatment.展开更多
基金supported by the Natural Science Foundation of Hunan Province(2020JJ4865 and S2021JJMSXM2689)the Hunan Provincial Clinical Medical Technology Innovation Guidance Project(2020SK53612),China.
文摘目的分析解放军306医院心脏中心急性ST段抬高型心肌梗死(STEMI)救治体系中不同性别患者之间再灌注时间延迟的分布。方法纳入2011年1月-2015年12月解放军306医院连续急诊收治并符合入选标准的STEMI患者325例,依据性别不同分为男性组(268例)和女性组(57例),分析各急救时间,包括发病(SO)至首次医疗接触(FMC)时间(SO-to-FMC)、转运时间(FMC-to-D)、FMC-to-B、导管室启动延迟时间、介入操作延迟时间、急诊至球囊扩张血管再通时间(D-to-B)等,并观察预后。结果尽管女性患者的院前延迟时间中位数(160.0min)和So-to-FMC中位数(100.0min)较男性(分别为119.5min和69.5min)延长,但差异无统计学意义,其余各项再灌注延迟时间差异也无统计学意义(P>0.05)。女性患者合并高血压、糖尿病者比例较高,吸烟率明显低于男性(P<0.05);两组STEMI患者30d内和1年内的主要心脑血管不良事件(MACCE)发生率(男性5.22% vs 女性5.26%;男性10.82% vs 女性8.77%)差异无统计学意义(P>0.05)。结论性别因素对再灌注延迟的影响正逐渐弱化。
文摘Objective There are still a high proportion of patients with ST-segment elevation myocardial infarction （STEMI） missing out early reperfusion even in the primary percutaneous coronary intervention （PCI） era. Most of them are stable latecomers, but the optimal time to undergo delayed PCI for stable ones remains controversial. Methods We investigated all STEMI patients who underwent delayed PCI （2-28 days after STEMI） during 2007-2010 in Beijing and excluded patients with hemodynamic instability. The primary outcome was maj or adverse cardiovascular events （MACEs）. Results This study finally enrolled 5,417 STEMI patients and assigned them into three groups according to individual delayed time （Early group, 55.9%; Medium group, 35.4%; Late group, 8.7%）. During 1-year follow-up, MACEs occurred in 319 patients. The incidence of MACEs were respectively 7.1%, 5.6% and 6.7% among three groups. The Medium group had less recurrent myocardial infarction plus cardiac death （hazard ratio, 0.525; 95% confidence interval, 0.294-0.938, P = 0.030） than Late group and less repeat revascularization （hazard ratio, 0.640; 95% confidence interval, 0.463-0.883, P = 0.007） than Early group in pairwise comparisons. We depicted the incidence of major adverse cardiovascular event （MACE） by delayed time as a quadratic curve and found the bottom appeared at day 14. Conclusions The delayed PCI time varied in the real-world practice, but undergoing operations on the second week after STEMI had greater survival benefit and less adverse events for whom without early reperfusion and hemodynamic instability.
文摘Rooting ability of indole 3-butyric acid （IBA）-induced stem cuttings in vegetative regeneration experiments depends on various parameters, which can be entrenched using sprouting value index （SVI）, a mathematical approach. In this study, field studies were carried out in Tabebuia rosea to generate clonal planting stock regeneration using three rooting medium at a location in Central Kerala, Peninsular India, for three consecutive years from October 2014 till June 2016 at four months regular intervals. Three IBA concentrations, viz., 200, 500 and 1,000 ppm, have been used and the data obtained was evaluated using SVI method in order to establish the suitable medium, which gives the maximum rooting results. Control cuttings did not record rooting in any of the trials. The high SVI was obtained when stem root cuttings planted in root trainers with coir pith compost （RTCP） for all the three concentration of IBA applied. Sprouting percentage was marked up and the delay in completion of sprouting/rooting initiation decreased by the use of IBA treatment.
