黛力新对老年冠心病心绞痛伴焦虑患者的临床疗效观察

目的:探讨黛力新辅助治疗老年冠心病心绞痛伴焦虑患者的临床疗效。方法:将70例老年冠心病心绞痛伴焦虑患者平分为两组,对照组常规心血管药物治疗,治疗组在常规采用心血管药物治疗的基础上加黛力新,2片/d。观察期均为6个月。结果:治疗组29例心绞痛发作每周≤1次,6例为每周2次以上,对照组则分别为11例、24例,两组比较,差异均有统计学意义,均为P<0.01。治疗组3个月、6个月时心肌缺血(ST段压低次数)分别为(77±17)次和(56±17)次,对照组则分别为(110±26)次和(119±27)次,两组比较,差异均有统计学意义(P<0.05)。治疗组再次住院2例,对照组7例,两组比较,差异有统计学意义(P<0.05)。结论:对老年冠心病绞痛伴焦虑患者,加黛力新治疗效果良好。

Is there any link between homocysteine and atherosclerosis？

I have read with interest the paper by Hart, et al. re- porting that homocysteine （Hey） is an independent risk fac- tor for non-culprit coronary lesions progression after 12 months of follow-up in elderly patients who has undergone percutaneous coronary stenting. Hcy-mediated increased lipid peroxidation and generation of free radicals results in in- flammation and endothelial dysfunction, which triggers atherosclerotic process. Coronary artery disease is also as- sociated with higher levels of Hcy.