Personalized cancer medicine has seen significant improvements over the past decade. Recent Elsevier conference: Miami winter symposium 2015 (MWS2015) "Towards Personalized Cancer Medicine" meeting was dedicated ...Personalized cancer medicine has seen significant improvements over the past decade. Recent Elsevier conference: Miami winter symposium 2015 (MWS2015) "Towards Personalized Cancer Medicine" meeting was dedicated to this exciting field, and focused on new progress in personalized drug development and antibody drug against checkpoint pathway. Tais meeting report summarizes the key developments presented and discussed at the meeting, with a focus on immunotherapy, especially on the CTLA-4 and PD-1/PD-L1 pathways. The monoclonal antibody drugs intervening these checkpoint pathways have the potential to play a larger role in personalize medicine within the near future. Here we intended to provide a comprehensive summary about ongoing trends and future perspectives on personalized medicine in cancer therapy.展开更多
Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by...Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by collecting and sorting out the relevant literature, and the analysis was made with the complex network. Results: It was found that Bai Jie Zi (白芥子 Semen Sinapis Albae), Xi Xin (细辛 Herba Asari), Gan Sui (甘遂 Radix Euphorbiae Kansui) and Yan Hu Suo (延胡索 Rhizoma Corydalis) were used as the basic prescriptions of drugs, Feishu (BL 13), Dazhui (GV 14) and Shanzhong (CV 17) were selected as the basic prescription of points. Conclusion: The knowledge obtained from the complex networks on the basic prescriptions of drugs and points for point-application in summer to treat diseases with attacks in winter can provide a data support for working out operation norms and carrying on verification research.展开更多
文摘Personalized cancer medicine has seen significant improvements over the past decade. Recent Elsevier conference: Miami winter symposium 2015 (MWS2015) "Towards Personalized Cancer Medicine" meeting was dedicated to this exciting field, and focused on new progress in personalized drug development and antibody drug against checkpoint pathway. Tais meeting report summarizes the key developments presented and discussed at the meeting, with a focus on immunotherapy, especially on the CTLA-4 and PD-1/PD-L1 pathways. The monoclonal antibody drugs intervening these checkpoint pathways have the potential to play a larger role in personalize medicine within the near future. Here we intended to provide a comprehensive summary about ongoing trends and future perspectives on personalized medicine in cancer therapy.
基金supported by the National Basic Research Program of China (No. 2006CB504601) the National Key Technology R&D Program (No. 2008BA53B00)
文摘Objective: To study the basic prescriptions of drugs and points for point application in summer to treat the diseases with attacks in winter and the law governing their compatibility. Methods: A database was set up by collecting and sorting out the relevant literature, and the analysis was made with the complex network. Results: It was found that Bai Jie Zi (白芥子 Semen Sinapis Albae), Xi Xin (细辛 Herba Asari), Gan Sui (甘遂 Radix Euphorbiae Kansui) and Yan Hu Suo (延胡索 Rhizoma Corydalis) were used as the basic prescriptions of drugs, Feishu (BL 13), Dazhui (GV 14) and Shanzhong (CV 17) were selected as the basic prescription of points. Conclusion: The knowledge obtained from the complex networks on the basic prescriptions of drugs and points for point-application in summer to treat diseases with attacks in winter can provide a data support for working out operation norms and carrying on verification research.