冬病夏治敷贴疗法联合清肺定喘汤治疗哮喘-慢性阻塞性肺疾病重叠综合征

目的探讨冬病夏治敷贴疗法联合清肺定喘汤治疗哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)的治疗效果。方法选取ACOS患者128例,按照随机数表法分为对照组与观察组,各64例,对照组给予常规西医治疗,观察组在对照组的基础上联合冬病夏治敷贴疗法联合清肺定喘汤治疗。对比2组临床疗效、免疫功能、肺功能、炎症因子,主要临床症状、体征评分。结果观察组治疗后的临床总有效率(90.63%,58/64)高于对照组(73.44%,47/64)(P<0.05)。治疗后,2组第1秒用力呼气容积(FEV_1)、用力肺活量(FVC)、最大呼气流量(PEF)升高,且观察组高于对照组(P<0.05);2组CD8^(+)降低,且观察组低于对照组(P<0.05);2组CD3^(+)、CD4^(+)/CD8^(+)、CD4^(+)升高,且观察组高于对照组(P<0.05);2组白介素-10(IL-10)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)降低,且观察组低于对照组(P<0.05);2组喘息、咳嗽、咳痰、湿啰音或哮鸣音评分均降低,且观察组低于对照组(P<0.05)。结论冬病夏治敷贴疗法联合清肺定喘汤治疗可有效改善哮喘-慢性阻塞性肺疾病重叠综合征患者的临床症状,可降低机体炎症因子水平、提高免疫水平,改善肺功能。

冬病夏治敷贴疗法联合孟鲁司特、噻托溴铵治疗ACOS的疗效

目的探究冬病夏治敷贴疗法联合孟鲁司特、噻托溴铵治疗哮喘-慢阻肺重叠综合征(ACOS)的疗效。方法选取2017年1—12月本院收治的86例ACOS患者为研究对象,按随机数表法分为对照组和观察组两组,每组各43例。对照组患者应用孟鲁司特、噻托溴铵治疗,观察组患者在对照组基础上实施冬病夏治敷贴疗法。比较2年后两组患者疗效,比较治疗前、治疗2年后两组患者中医症候积分、病情控制程度[哮喘控制测试评分(ACT)、慢性阻塞性肺疾病患者自我评估测试(CAT)]、肺功能[第1 s用力呼气容积(FEV1)、肺活量(FVC)、FEV1/FVC]。结果治疗2年后,观察组患者总体疗效高于对照组,差异有统计学意义(P<0.05),但两组总有效率比较,差异有统计学意义(P>0.05);两组中医症候积分均较治疗前下降,且观察组中医症候积分低于对照组,差异有统计学意义(P<0.05);两组ACT评分较治疗前上升,且观察组ACT评分高于对照组,差异均有统计学意义(P<0.05);两组CAT评分均较治疗前降低,且观察组CAT评分低于对照组,差异均有统计学意义(P<0.05);两组FEV1、FVC、FEV1/FVC均较治疗前上升,且观察组各指标均高于对照组,差异均有统计学意义(P<0.05)。结论冬病夏治敷贴疗法联合孟鲁司特、噻托溴铵治疗ACOS有助于改善总体疗效,能有效减轻患者症状,控制患者病情,并有利于改善肺功能。

Efficacy comparison of different forms of dog-days acupoint application for prevention and treatment of chronic bronchitis

Objective: To analyze the clinical effect of traditionaldog-days acupoint application and Magic Acupuncture Patch (Manji) in the prevention and treatment of chronic bronchitis (CB) in remission stage in the past five years, and explore the principle of action and effective stimulation, to provide the evidence for treating CB by acupoint application. Methods: A retrospective study was conducted on 405 patients with CB who met the inclusion criteria. All patients were treated with dog-days acupoint application or Magic Acupuncture Patch between 2013 and 2017. The clinical data of 405 patients were statistically analyzed to compare the prevention and treatment effects of dog-days acupoint application and Magic Acupuncture Patch, and different degrees of stimulation of dog-days acupoint application. Results: Among the dog-days acupoint application groups, the total effective rate was 63.6% in the light stimulation group, 93.1% in the moderate stimulation group, and 94.8% in the strong stimulation group. The differences in the total effective rate between the light stimulation group and the moderate stimulation group, as well as the strong stimulation group, were statistically significant (both P<0.05). There was no significant difference in the total effective rate between the moderate stimulation group and the strong stimulation group (P>0.05). The total effective rate was 83.9% in the dog-days acupoint application group, versus 45.4% in the Magic Acupuncture Patch group, and there was a statistically significant difference between the two groups (P<0.05). Conclusion: The efficacy of dog-days acupoint application in the prevention and treatment of CB is better than that of Magic Acupuncture Patch;the degree of stimulation is the basis for the effect of dog-days acupoint application on prevention and treatment of CB, and the moderate and strong stimulations are more appropriate.