This work aimed to prepare the nanospike surface-modified bionic porous titanium implants that feature favorableosteointegration performance and anti-bacterial functions.The implant was prepared using freeze casting,a...This work aimed to prepare the nanospike surface-modified bionic porous titanium implants that feature favorableosteointegration performance and anti-bacterial functions.The implant was prepared using freeze casting,and nanospikesurface-modification of the implant was performed using thermal oxidation.The pore morphology and size,mechanical properties,and osteogenic performance of the implants were analyzed and discussed.The results showed that when the volume ratio of titaniumpowder in slurry was set to be10%,the porosity,pore diameter,compressive strength,and elastic modulus of the porous sampleswere(58.32±1.08)%,(126.17±18.64)μm,(58.51±20.38)MPa and(1.70±0.52)GPa,respectively.When the porous sample wassintered at a temperature of1200°C for1h,these values were(58.24±1.50)%,(124.16±13.64)μm,(54.77±27.55)MPa and(1.63±0.30)GPa,respectively.The nanospike surface-modified bionic porous titanium implants had favorable pore morphology andsize,mechanical properties and osteointegration performance through technology optimization,and showed significant clinicalapplication prospect.展开更多
基金Projects(51290295,51305464) supported by the National Natural Science Foundation of ChinaProject(2016JJ6156) supported by the Natural Science Foundation of Hunan Province,China+1 种基金Project(2016JC2064) supported by the Key Research and Development Program of Hunan Province,ChinaProject(20130162120094) supported by the Specialized Research Fund for the Doctoral Program of Higher Education,China
文摘This work aimed to prepare the nanospike surface-modified bionic porous titanium implants that feature favorableosteointegration performance and anti-bacterial functions.The implant was prepared using freeze casting,and nanospikesurface-modification of the implant was performed using thermal oxidation.The pore morphology and size,mechanical properties,and osteogenic performance of the implants were analyzed and discussed.The results showed that when the volume ratio of titaniumpowder in slurry was set to be10%,the porosity,pore diameter,compressive strength,and elastic modulus of the porous sampleswere(58.32±1.08)%,(126.17±18.64)μm,(58.51±20.38)MPa and(1.70±0.52)GPa,respectively.When the porous sample wassintered at a temperature of1200°C for1h,these values were(58.24±1.50)%,(124.16±13.64)μm,(54.77±27.55)MPa and(1.63±0.30)GPa,respectively.The nanospike surface-modified bionic porous titanium implants had favorable pore morphology andsize,mechanical properties and osteointegration performance through technology optimization,and showed significant clinicalapplication prospect.
