The metastable state and nucleation kinetics of clindamycin phosphate (CP) in cooling crystallization were studied by metastable zone width (MZW) method and induction time method. By correlating the MZW experimental r...The metastable state and nucleation kinetics of clindamycin phosphate (CP) in cooling crystallization were studied by metastable zone width (MZW) method and induction time method. By correlating the MZW experimental results with temperature, agitation rate and cooling rate, it is found that the correlation result shows good agreement with the change trend of MZW. The critical nucleation parameters were evaluated based on the classical theory of nucleation; both the interfacial tension and the radius of critical nucleus increased with the decrease of relative supersaturation. The effect of supersaturation on the nucleation rate was analyzed. It is indicated that the new phase formation of CP is governed by mononuclear mechanism.展开更多
The glass formation was intensively studied for Fe-based alloys. Parameters defining kinetics and thermodynamic behavior of crystallization were calculated using calorimetric measurements and physical properties of co...The glass formation was intensively studied for Fe-based alloys. Parameters defining kinetics and thermodynamic behavior of crystallization were calculated using calorimetric measurements and physical properties of constituent elements. It is found that the critical cooling rate Rc estimated by combining kinetic and thermodynamic parameters highly correlates with measured Rc found in literatures with correlation coefficient R2=0.944, and alloy compositions with high melting enthalpy AHm can easily form glass even without high undercooling and high value of the ,β-parameter of Tumbull＇s theory, revealing that the glass formation in this group of alloys is mostly controlled by growth limitation. This combination of kinetic and thermodynamic parameters can be used to determine alloy composition with good glass forming ability in Fe-based alloys just using physical properties of alloying elements and calorimetric measurements.展开更多
基金Supported by the Program of Introducing Talents of Discipline to Universities (No. B06006)
文摘The metastable state and nucleation kinetics of clindamycin phosphate (CP) in cooling crystallization were studied by metastable zone width (MZW) method and induction time method. By correlating the MZW experimental results with temperature, agitation rate and cooling rate, it is found that the correlation result shows good agreement with the change trend of MZW. The critical nucleation parameters were evaluated based on the classical theory of nucleation; both the interfacial tension and the radius of critical nucleus increased with the decrease of relative supersaturation. The effect of supersaturation on the nucleation rate was analyzed. It is indicated that the new phase formation of CP is governed by mononuclear mechanism.
基金Projects(51174094, 51101059) supported by the National Natural Science Foundation of China
文摘The glass formation was intensively studied for Fe-based alloys. Parameters defining kinetics and thermodynamic behavior of crystallization were calculated using calorimetric measurements and physical properties of constituent elements. It is found that the critical cooling rate Rc estimated by combining kinetic and thermodynamic parameters highly correlates with measured Rc found in literatures with correlation coefficient R2=0.944, and alloy compositions with high melting enthalpy AHm can easily form glass even without high undercooling and high value of the ,β-parameter of Tumbull＇s theory, revealing that the glass formation in this group of alloys is mostly controlled by growth limitation. This combination of kinetic and thermodynamic parameters can be used to determine alloy composition with good glass forming ability in Fe-based alloys just using physical properties of alloying elements and calorimetric measurements.
