High intensity focused ultrasound(HIFU)therapy is an effective method in clinical treatment of tumors,in order to explore the bio-heat conduction mechanism of in multi-layer media by concave spherical transducer,tempe...High intensity focused ultrasound(HIFU)therapy is an effective method in clinical treatment of tumors,in order to explore the bio-heat conduction mechanism of in multi-layer media by concave spherical transducer,temperature field induced by this kind of transducer in multi-layer media will be simulated through solving Pennes equation with finite difference method,and the influence of initial sound pressure,absorption coefficient,and thickness of different layers of biological tissue as well as thermal conductivity parameter on sound focus and temperature distribution will be analyzed,respectively.The results show that the temperature in focus area increases faster while the initial sound pressure and thermal conductivity increase.The absorption coefficient is smaller,the ultrasound intensity in the focus area is bigger,and the size of the focus area is increasing.When the thicknesses of different layers of tissue change,the focus position changes slightly,but the sound intensity of the focus area will change obviously.The temperature in focus area will rise quickly before reaching a threshold,and then the temperature will keep in the threshold range.展开更多
In this study,a theoretical model was established for predicting the equilibrium shape of the droplet on flat and spherical surfaces.The theoretical equilibrium shape of heavy droplets could be obtained once contact a...In this study,a theoretical model was established for predicting the equilibrium shape of the droplet on flat and spherical surfaces.The theoretical equilibrium shape of heavy droplets could be obtained once contact angle and volume of droplets were given.It showed that the predictions of the theoretical flat model were in good agreement with the shape obtained by Surface Evolver when the contact angle is below 120 and the droplet size is on the order of capillary length.This available range will decrease and increase when the heavy droplet is on convex and concave spherical surface,respectively,in contrast to that on flat surface.The available range will decrease more for higher curvature of convex spherical surfaces.展开更多
基金Project(11174077)supported by the National Natural Science Foundation of ChinaProject(11JJ3079)supported by the Hunan Provincial Natural Science Foundation of ChinaProjects(12C0237,11C0844)supported by the Science Research Program of Education Department of Hunan Province,China
文摘High intensity focused ultrasound(HIFU)therapy is an effective method in clinical treatment of tumors,in order to explore the bio-heat conduction mechanism of in multi-layer media by concave spherical transducer,temperature field induced by this kind of transducer in multi-layer media will be simulated through solving Pennes equation with finite difference method,and the influence of initial sound pressure,absorption coefficient,and thickness of different layers of biological tissue as well as thermal conductivity parameter on sound focus and temperature distribution will be analyzed,respectively.The results show that the temperature in focus area increases faster while the initial sound pressure and thermal conductivity increase.The absorption coefficient is smaller,the ultrasound intensity in the focus area is bigger,and the size of the focus area is increasing.When the thicknesses of different layers of tissue change,the focus position changes slightly,but the sound intensity of the focus area will change obviously.The temperature in focus area will rise quickly before reaching a threshold,and then the temperature will keep in the threshold range.
基金supported by the National Natural Science Foundation of China (Grant No. 10902015)the Research Funds for the Doctoral Program of Higher Education of China (Grant No. 20091101120001)
文摘In this study,a theoretical model was established for predicting the equilibrium shape of the droplet on flat and spherical surfaces.The theoretical equilibrium shape of heavy droplets could be obtained once contact angle and volume of droplets were given.It showed that the predictions of the theoretical flat model were in good agreement with the shape obtained by Surface Evolver when the contact angle is below 120 and the droplet size is on the order of capillary length.This available range will decrease and increase when the heavy droplet is on convex and concave spherical surface,respectively,in contrast to that on flat surface.The available range will decrease more for higher curvature of convex spherical surfaces.
