徜徉在汉字的乐园里——小学起始年级分周专题识字的设计与运用

让学生在兴趣盎然中大量识字，一直是低年级语文教师的追求。文章探讨如何以周为单位设计识字专题，并通过激发兴趣，让孩子主动识字；巧妙实践，让孩子快乐识字；多元评价，让孩子收获喜悦等方面开展主题识字活动，从而显著提高识字教学效率。

分层次周目标教学法在心脏外科护理教学中的应用

分层次周目标教学法是一种针对不同能力水平学生的教学方法,在心脏外科护理教学中具有积极的应用效果。该教学法通过合理的学生分层、设定不同层次的周目标、提供相应的学习资源和方法、及时评估和指导以及制定科学的评估标准,能够更好地满足不同能力水平学生的学习需求,提高教学效果和学生满意度,培养自主学习能力和创新精神,可以更好地发掘学生的潜力和优势。因此,建议在心脏外科护理学课堂中广泛应用分层次周目标教学法,为每个学生提供明确可实现的目标,激发他们的学习积极性和主动性,为培养优秀的专业护士打下坚实的基础。

一种粗铣刀周齿分屑槽的数控磨削工艺算法

针对粗铣刀分屑槽形状的磨削工艺,对粗铣刀周齿分屑槽结构参数进行了定义,建立了加工坐标系及切深引导曲线方程;借助运动学理论,提出了砂轮磨削姿态和砂轮磨削轨迹的计算方法;在VC++环境开发了一套算法模块,并对其进行了仿真验证及与Numroto磨削软件的仿真结果对比。结果表明,该轨迹算法能够较好的实现预期效果,具有较好的刀具结构扩展性和加工精度。

分层次周目标教学法结合案例模拟在妇产科临床实践教学中的应用效果

探讨分层次周目标教学法结合案例模拟在妇产科临床实践教学中的应用效果。方法 选择2021年8月~2022年5月某三级甲等综合性医院妇产科参加实习的102名临床医学实习生为研究对象,将2021年8月至12月实习的临床医学生为对照组,2022年1月至5月实习的临床医学生为干预组,每组各51例,对照组采用常规临床实践教学模式,干预组采用分层次周目标教学法结合案例模拟临床实践教学模式,比较两组医学生的评判性思维得分比较两组医学生的出科成绩、评判性的思维能力以及教学满意度。结果 干预组理论考核成绩为96±1.43分,临床技能考核成绩为95±2.05分,平均成绩为95±1.86分,评判性思维总分为(288±19.85)分,总满意度得分为评分(97±1.46)分;对照组理论考核成绩为90±1.59分,临床技能考核成绩为86±1.65分,平均成绩为87±2.35分,评判性思维总分为(265±18.46)分,总满意度得分为评分(88±3.25)分,均具有统计学差异P<0.05,有统计学差异。结论 通过将妇产科临床实践教学目标和内容制成分层次周目标计划表,结合经典案例的模拟重现,完善妇产科临床教学方法,激发医学生学习兴趣和自主能力,提高学生妇产科临床实践学习效果。

立铣刀周齿分屑槽的砂轮磨削轨迹算法研究

周齿分屑槽是粗加工铣刀的一种新型结构,可减小切削刃宽度,便于排屑,降低切削力,改善刀具切削性能,提高刀具使用寿命。为了提高周齿分屑槽的磨削加工精度和结构参数适应性,研究了周齿分屑槽在数控磨削过程中的砂轮磨削轨迹求解方法,定义了周齿分屑槽相关坐标系及其转换关系,定义了周齿分屑槽的结构参数和砂轮磨削基准姿态,构建了周齿分屑槽的槽底控制曲线模型。在此基础上,运用坐标变换矩阵描述砂轮运动方式,推导了基于工件坐标系的砂轮磨削轨迹的计算方法,编写了基于VC++环境的程序算法,输出得到工件坐标系下的砂轮磨削位置和姿态,并进行一系列仿真测试,验证了该磨削轨迹算法的有效性。

分层次周目标教学法在心脏外科护理规范化培训中的应用

目的观察分层次周目标教学法在心脏外科临床护理规范化培训中的应用效果。方法选取2014—2017年我科新入职的护理人员32名为观察组,选取2010—2013年我科新入职的护理人员30名为对照组。对照组护理人员采用传统带教方法,观察组采用分层次周目标教学法。培训结束后,对护理人员进行心脏外科护理学理论知识、心脏外科护理实践操作能力考核。结果观察组护理人员的理论知识考试得分、实践操作考试评分均高于对照组,差异有统计学意义(P<0.05)。结论在心脏外科临床护理规范化培训中应用分层次周目标教学法可提高临床护理教学质量。

分层次周目标教学在胸外科临床护理教学中的应用

目的:探讨分层次周目标教学法在胸外科临床护理实习带教中的应用效果。方法:将2010年7月至2012年5月在胸外科实习的240名护生按时间分为对照组112名和实验组128名,对照组采用传统带教法,实验组采用分层次周目标教学法,比较两组护生出科时的理论和操作考核成绩、实习期间的综合能力测评结果以及护生对带教老师的满意度。结果:两组护生各项成绩及对带教老师的满意度比较,差异有统计学意义(P<0.05)。结论:分层次周目标教学法可提高临床护理教学质量,能取得教学相长的效果。

Comparison of Soleus Muscle Fibers in Rats and Rabbits at Different Stages of Postnatal Development

In the present study,the effects of postnatal development on the number and distribution of skeletal muscle fibers of different types in hind leg of rat and rabbit were studied.The soleus muscles of rats aged 2 days,2,4,6,8,and 10 weeks (body weight 10,32,95,190,280,and 320 g),and rabbits aged 2 days,2,4,8,12,16,20,and 24 weeks (body weight 100,220,400,750,1 200,1 600,2 100,and 2 500 g) were stained with succinic dehydrogenase.With an image analysis system,the X-Y coordinates of fibers were used to analyze the growth-related changes.The results of present study showed that three types of fibers were found in the soleus muscles of rat and rabbit,i.e.,type Ⅰ (slow oxidative),ⅡX (fast oxidative),and ⅡA (fast oxidative glycolytic).The type Ⅰ fibers were present throughout the muscle that had a uniform distribution and tended to increase in number with aging.Type ⅡX fibers were scattered throughout the muscle and decreased markedly in number with aging.Type ⅡA fibers were located at the central and deep regions,and showed a little or no change in number and distribution with aging.While be of age,type ⅡA and ⅡX fibers became restricted to the superficial region.No type ⅡB fibers were detected.Type ⅡA fibers had the largest diameter,type Ⅰ intermediate and type ⅡX the smallest.Mean cross-sectional area of each type fibers of rabbits was larger than that of rats.The present results indicate that the number and distribution of muscle fibers of different types in hind limb of rat and rabbit change with the process of postnatal growth.

On the Existence of Periodic Solutions of a Class Nonlinear Differential Systems

One method to show the existence of ω-periodic system is given. This method is based on the ultimately boundedness of the solution of the systems. By using comparing theorem and discussing some one dimensional equations the main results are obtained.

Temperature evolution and fatigue life evaluation of AZ31B magnesium alloy based on infrared thermography

The surface temperature of extruded AZ31B alloy plate was measured by infrared thermograph in air during tension and high-cycle fatigue tests. The mechanism of heat production was discussed and the value of critical fatigue damage temperature was calculated according to the P—ΔT curve. Results show that the variation trend of temperature is different between tension and fatigue tests. The temperature evolution in tension test consists of four stages： linear decrease, reverse linear increase, abrupt increase, and final drop. The initial decrease of temperature is caused by thermal elastic effect, which is corresponding to the elastic deformation in tension progress. When cyclic loading is above the fatigue limit, the temperature evolution mainly undergoes five stages： initial increase, steep reduction, steady state, abrupt increase, and final drop. The peak temperature in fatigue test is caused by strain hardening that can be used to evaluate the fatigue life of magnesium alloy. The critical temperature variation that causes the fatigue failure is 3.63 K. When ΔT≤3.63 K, the material is safe under cyclic loading. When ΔT3.63 K, the fatigue life is determined by cycle index and peak temperature.

Periodic Solution and Global Stability of a Kind of Nonlinear Differential Equation

In this paper, it is discussed the model of a kind of nonlinear differential, equation d s d t=1-s-x 1s 0δQ 2(m 1s 0sk 1+s 0s-k) d x 1 d t=x 1Q(m 1s 0sk 1+s 0s-k)-x 1-x 2m 2x 1/Qk 2+x 1/Q d x 2 d t=x 2Q m 2x 1/Qk 2+x 1/Q-x 2.It is proved that the system is exist at least one stable periodic solution on under the following condition:m 2x * 2(k 1δ+s 0δ-Qλ 2-x * 2) 2】m 1δk 1(k 2+Q 2λ 2) 2.Furthermore, ifm 2x * 2(k 1δ+s 0δ-Qλ 2-x * 2) 2【m 1δk 1(k 2-Q 2λ 2) 2mold true them equilibrium point (s *,x * 1,x * 2)∈ set Ω is global asymptotic stable.

Cell Cycle Kinetic Analysis in the Cortical Regions of the Lentil Primary Root During Germination

Cell cycle kinetic activity in the cortical cells of the lentil (Lens culinaris Me-die. cv. Verte du Puy) primary root during germination was examined both temporally and spatially. Immunohistochemical and cytological evidence indicated that DNA replication and cell division started in the cortical cells of tire lentil primary root after around 13 and 17 h of imbibition, respectively. The first cells in DNA synthesis and the First mitotic figures all appeared in the cortical cells about I mm front the root-cap junction, but these divided cells had synthesized their DNA during the maturity of seed instead of during germination. The kinetic pattern of activity of the first cell cycle showed that these cells were not activated synchronously, but re-entered the cell cycle in turn depending on their places in the root tip, However, the adjacent cells partially synchronously proceeded their cell cycle.

Cyclical fluctuations of real estate investment across regions in urban China

Taking the concrete conditions of each region into full consideration, the Chinese real estate market is divided into an eastern market, a central market and a western market. For each market, the autoregressive integrated moving average （ARMA） model is established and spectral analysis is carded out to better understand the changes in the real estate markets in each region. The results show the investment levels and several kinds of cycles within each market. The level of real estate investment （LREI）in the eastern region is the higiaest, and the short cycle of investment is about 4 to 5 years; the LREI in the central region is in the middle, and the short cycle of investment is about 2 to 3 years; the LREI in the western region has been rapidly increasing in recent years, and the short cycle of investment is about 4 to 5 years. Real estate investment in each area has reached a peak and completed a middle-cycle movement after a period of sustained recession and an upsurge process, which has taken about 9 to 10 years.

A Novel Three-parameter Flow Cytometric Analysis for Cell Cycle

To set up a three-parameter method for cell cycle analysis by two-laser flowcy-tometer, which can detect two types of cyclin plus DNA content in one measurement, and thatanalyze unscheduled expression of cyclins. Methods: Three-color fluorescence was used for analysisof two types of cyclins and DNA content simultaneously in individual cells by two-laser flowcytometry. MOLT-4 cells were used to study the expression of major cyclins in mammalian cells. ATriton-X100 permeabilization procedure was optimized for detection of two types of cyclins. Onecyclin was stained directly with a FITC-conjugated monoclonal antibody (mAb), and the other,indirectly with RPE-Cy5-conjugated secondary antibody, while DNA was stained with the fluorochromeDAPI. mAMSA and mimosine treated MOLT-4 cells were used to test this three-parameter method.Results: Permeabilization with 0.5% Triton-XlOO in PBS containing 1% BSA for 5 min on ice providedoptimal conditions for the simultaneous labelling of two cyclins plus DNA in single cells. It wasfound that the emission spectrum of the three dyes (DAPI, FITC and RPE-Cy5) could be measured withno compensation. Based on cyclinA/cyclinE/DNA flow cytometric analysis, asynchronously growingMOLT-4 cells could be divided into 6 compartments (G1o, G1e, G1l, S, G2, and M) simultaneously,allowing for analysis of cell cycle phase specific perturbations without the necessity of cellsynchronization. Unscheduled cyclin B1 expression was observed in G1 cells treated with mimosine andcyclin E in G2 cells treated with mAMSA. We found that unscheduled cyclin expression paralleledexpected cyclin expression. Conclusion: Thus, three-color FCM analysis of cells may not only beapplied to measure unscheduled vs. expected cyclin expression but may also be used to estimate thefraction of cycling cells in up to 6 cell populations.

Existence of Periodic Solutions for Generalized Liénard-Typed Functional Differential Equations

The existence of periodic solutions for a kind of generalized Liénard typed functional differential equation is studied. By means of the continuation theorem of coincidence degree theory, existence criteria are established for the existence of periodic solutions and some previous results are extended.

Existence of Periodic Solutions of Nonlinear Neutral Differential Equation with Deviating Argument

Existence criteria is established for the periodic solution of the nonlinear neutral delay differential equation x′(t)=f(t,x(t),x(t-τ 1(t)),x′(t-τ 2(t)))+p(t) by means of an abstract continuous theorem of k-set contractive operator and some analysis technique.

DOUBLE BIFURCATION OF NONLINEAR DUFFING'S OSCILLATOR

The transition boundaries of period doubling on the physical parameter plane of a Duffing system are obtained by the general Newton′s method, and the motion on different areas divided by transition boundaries is studied in this paper. When the physical parameters transpass the boundaries, the solutions of period T =2π/ω will lose their stability, and the solutions of period T =2π/ω take place. Continuous period doubling bifurcations lead to chaos.

Existence of Many and Infinitely Many Periodic Solutions for Some Types of Differential Delay Equations

J.Kaplan and J.Yorke's method is extended to establish the exis- tence of many and infinitely many periodic solutions for the DDEs (t) =±f(x(t-1))±f(x(t-2))and (t)=±f(x(t-1).

Thermal Induced Periodic Phase Separation in Polymer Blends

Simulations were carried out for studying the periodic phase separation of a symmetric binary polymer blend on the basis of Cahn-Hilliard-Cook theory. The time dependent interaction parameter x（τ） was assumed to undergo a step-wise oscillation. The hierarchic structures composed of both large and small domains were obtained. The mechanism of the periodic formation of hierarchic structures was also demonstrated.

p21^(WAF1/CIP1) Gene DNA Sequence Change and Their Relationship with the Phenotype of Human Osteosarcoma

Objective: To investigate the p21WAF1 /CIP1gene DNA sequence change and their relationship with the phenotype of human osteosarcoma. Methods: p21WAF1 /CIP1gene DNA of 36 osteosarcoma spec- imens was examined by using polymerase chain reaction-single strand conformation polymorphism (PCR- SSCP) method. The PCR products were sequenced directly. Results: In p21WAF1 /CIP1 gene exon3 of 36 cases of human osteosarcoma, the change of C→T in the p21WAF1 /CIP1gene CDNA sequence of position 609th occurred in 17 cases with the incidence being 44.4%. In 10 normal blood samples, DNA sequence analysis showed the change of C→T in the p21WAF1 /CIP1gene CDNA sequence of position 609th occurred in 8 cases with the incidence being 80%. Conclusion: The novel location of p21WAF1 /CIP1gene polymorphism of osteosarcoma, but not mutation was de?ned, and this location might provide the meaningful reference for the further research of p21WAF1/CIP1 gene.p2lWAF1/CIP1基因DNA序列分析及其与骨肉瘤表型的关系