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生物钟基因网络中分子噪声诱导的日夜节律振荡及相干共振 被引量:3
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作者 易鸣 贾亚 +1 位作者 刘泉 詹璇 《物理学报》 SCIE EI CAS CSCD 北大核心 2008年第1期621-627,共7页
研究了果蝇细胞内生物钟基因调节网络的分子噪声,特别讨论了生物钟系统处于略微远离振荡区域的稳态时分子噪声对于时钟蛋白的日夜节律振荡的影响.结果表明:(1)虽然时钟蛋白合成或者衰减的生化反应事件是在随机的时间间隔里随机发生的,... 研究了果蝇细胞内生物钟基因调节网络的分子噪声,特别讨论了生物钟系统处于略微远离振荡区域的稳态时分子噪声对于时钟蛋白的日夜节律振荡的影响.结果表明:(1)虽然时钟蛋白合成或者衰减的生化反应事件是在随机的时间间隔里随机发生的,但系统可以依赖自身固有的调节机理诱导出明显的日夜节律振荡;(2)分子噪声诱导的日夜节律振荡的相干性可以在合适的分子噪声水平下到达最佳,说明了相干共振现象的发生. 展开更多
关键词 生物钟 分子噪声 日夜节律振荡 相干共振
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马氏和半马氏反应系统中的噪声效果分析
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作者 曹文洁 滕嘉琪 +1 位作者 陈浩文 周天寿 《中山大学学报(自然科学版)(中英文)》 CAS CSCD 北大核心 2024年第6期291-300,共10页
基因调控网、信号转导网、代谢控制网和蛋白质相互网等生物分子网络是计算系统生物学的主要研究对象.从随机过程的观点,这些网络可以划分为马氏反应网和非马氏反应网,依赖于分子机制的实验测定.另一方面,由于生化反应事件是随机发生的,... 基因调控网、信号转导网、代谢控制网和蛋白质相互网等生物分子网络是计算系统生物学的主要研究对象.从随机过程的观点,这些网络可以划分为马氏反应网和非马氏反应网,依赖于分子机制的实验测定.另一方面,由于生化反应事件是随机发生的,这必然会导致反应物种水平的涨落(即生化反应系统是固有噪声的).这种分子噪声可能在自然选择、细胞命运决定、细胞内部过程等起着重要作用.一个未完全解决的问题是分子噪声的生物学功能是什么.本文分别分析地导出一般的马氏生化网络和一般的半马氏生化网络中分子噪声对各个反应物种水平影响的计算公式,并对一般的朗之万方程,建立了小噪声影响系统平衡态和特征值的两个实用定理.此外,以广义生灭过程作为一个例子,分析地显示出分子记忆的效果等同于反馈的引入.本文的分析结果既有宽广的应用前景,也为基于实验数据的统计推断奠定了基础. 展开更多
关键词 马氏反应网络 半马氏反应网络 分子噪声 化学主方程
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基于噪声免疫腔增强光外差分子光谱技术实现光纤激光器到1530.58 nmNH_3亚多普勒饱和光谱的频率锁定 被引量:3
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作者 贾梦源 赵刚 +9 位作者 周月婷 刘建鑫 郭松杰 吴永前 马维光 张雷 董磊 尹王保 肖连团 贾锁堂 《物理学报》 SCIE EI CAS CSCD 北大核心 2018年第10期80-90,共11页
噪声免疫腔增强光外差分子光谱技术(NICE-OHMS)由于结合了频率调制光谱与腔增强光谱两种技术,不仅可以将激光耦合到高精细度谐振腔大幅提高腔内功率,还可以实现低气压样品气体的高灵敏测量,因此基于该技术可以实现分子吸收线的饱和,获... 噪声免疫腔增强光外差分子光谱技术(NICE-OHMS)由于结合了频率调制光谱与腔增强光谱两种技术,不仅可以将激光耦合到高精细度谐振腔大幅提高腔内功率,还可以实现低气压样品气体的高灵敏测量,因此基于该技术可以实现分子吸收线的饱和,获得亚多普勒光谱,从而能作为激光频率锁定的参考.本文基于光纤激光器的NICE-OHMS技术,将光纤激光器频率锁定到NH3的亚多普勒吸收线上.首先分析了基于Pound-Drever-Hall和DeVoe-Brewer技术实现激光到腔模和调制频率到腔自由光谱区频率锁定的性能,之后在腔内气压为70 mTorr条件下,测量了半高全宽为2.05 MHz的NH3亚多普勒信号,最后将1.53μm的光纤激光器频率锁定到该亚多普勒吸收线上,相对频率偏差为16.3 kHz,阿伦方差结果显示,136 s积分时间下频率稳定度达到1.6×10^(-12). 展开更多
关键词 噪声免疫腔增强光外差分子光谱技术 光纤激光器 亚多普勒吸收线 频率稳定度
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Robust Multiparty Quantum Secret Key Sharing Over Two Collective-Noise Channels via Three-Photon Mixed States 被引量:7
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作者 WANG Zhang-Yin YUAN Hao GAO Gan Shou-Hua 《Communications in Theoretical Physics》 SCIE CAS CSCD 2006年第4X期607-609,共3页
We present a robust (n, n)-threshold scheme for multiparty quantum secret sharing of key over two collectivenoise channels (i.e., the collective dephasing channel and the collective rotating channel) via three-pho... We present a robust (n, n)-threshold scheme for multiparty quantum secret sharing of key over two collectivenoise channels (i.e., the collective dephasing channel and the collective rotating channel) via three-photon mixed states, In our scheme, only if all the sharers collaborate together can they establish a joint key with the message sender and extract the secret message from the sender's encrypted message. This scheme can be implemented using only a Bell singlet, a one-qubit state and polarization identification of single photon, so it is completely feasible according to the present-day technique. 展开更多
关键词 multiparty quantum secret key sharing collective-noise channel
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Compressed Multi-image Reconstruction Based on Quantization Noise Distribution 被引量:1
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作者 程燕 方向忠 《Journal of Donghua University(English Edition)》 EI CAS 2007年第6期756-761,共6页
Because of the quantization noise introduced during the compression,super-resolution reconstruction(SRR)techniques are complicated for the compressed images.This paper aims to incorporate the prior knowledge of discre... Because of the quantization noise introduced during the compression,super-resolution reconstruction(SRR)techniques are complicated for the compressed images.This paper aims to incorporate the prior knowledge of discrete cosine transform(DCT)coefficients into modeling the quantization noise.The spatial covariance matrix of the quantization noise is estimated by utilizing the Laplacian distribution of the alternating current(AC)coefficients.After estimating the spatial joint covariance of overall noises for the imaging system,we propose a general Bayesian framework to enhance the resolution for compressed images.Experiments demonstrate the effectiveness of the proposed algorithm and show the superiority to previous methods in objective and subjective aspects. 展开更多
关键词 SUPER-RESOLUTION quantization noise COVARIANCE BAYESIAN
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Protein Conformational Change Based on a Two-dimensional Generalized Langevin Equation
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作者 王莹希 林广双木 +1 位作者 赵南蓉 严以京 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2011年第5期597-603,I0004,共8页
A two-dimensional generalized Langevin equation is proposed to describe the protein conformational change, compatible to the electron transfer process governed by atomic packing density model. We assume a fractional G... A two-dimensional generalized Langevin equation is proposed to describe the protein conformational change, compatible to the electron transfer process governed by atomic packing density model. We assume a fractional Gaussian noise and a white noise through bond and through space coordinates respectively, and introduce the coupling effect coming from both fluctuations and equilibrium variances. The general expressions for autocorrelation functions of distance fluctuation and fluorescence lifetime variation are derived, based on which the exact conformational change dynamics can be evaluated with the aid of numerical Laplace inversion technique. We explicitly elaborate the short time and long time approximations. The relationship between the two-diraensional description and the one-dimensional theory is also discussed. 展开更多
关键词 Protein conformational fluctuation Two-dimensional generalized Langevinequation Atomic packing density model Fractional Gaussian noise
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A geometric Model for the Spatial Correlation of an Acoustic Vector Field in Surface-generated Noise 被引量:4
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作者 Yiwang Huang (1) huangyiwang@hrbeu.edu.cn Qunyan Ren (12) Ting Li (3) 《Journal of Marine Science and Application》 2012年第1期119-125,共7页
Spatial correlation of sound pressure and particle velocity of the surface noise in horizontally stratified media was demonstrated, with directional noise sources uniformly distributed on the ocean surface. In the eva... Spatial correlation of sound pressure and particle velocity of the surface noise in horizontally stratified media was demonstrated, with directional noise sources uniformly distributed on the ocean surface. In the evaluation of particle velocity, plane wave approximation was applied to each incident ray. Due to the equivalence of the sound source correlation property and its directivity, solutions for the spatial correlation of the field were transformed into the integration of the coherent function generated by a single directional source. As a typical horizontally stratified media, surface noise in a perfect waveguide was investigated. Correlation coefficients given by normal mode and geometric models show satisfactory agreement. Also, the normalized covariance between sound pressure and the vertical component of particle velocity is proportional to acoustic absorption coefficient, while that of the surface noise in semi-infinitely homogeneous space is zero. 展开更多
关键词 spatial correlation sound pressure and particle velocity surthce noise stratitied media ray theory
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Steady-State Analysis of a Two-Mode Laser System with Cross-Correlation Between Real and Imaginary Parts of Quantum Noise
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作者 戴祖诚 向友林 梅冬成 《Communications in Theoretical Physics》 SCIE CAS CSCD 2010年第5期889-892,共4页
An inhomogeneously broadened two-mode laser system with cross-correlations between the real and imag- inary parts of quantum noise is considered. The Fokker-Planek equation of the system is derived by the phase-lockin... An inhomogeneously broadened two-mode laser system with cross-correlations between the real and imag- inary parts of quantum noise is considered. The Fokker-Planek equation of the system is derived by the phase-locking method. The steady-state probability distribution, the mean light intensity, the normalization autocorrelation function, and cross correlation function are calculated. The results indicate that: (i) The cross-correlation between the real and imaginary parts of quantum noise can cause the stationary probability distribution from one peak structure to two extrema structure when the laser system is operated above threshold; (ii) The cross-correlation between the real and imaginary parts of quantum noise enhance the light intensity fluctuation and decrease the laser output when the laser system is operated below or near threshold; (iii) The effect of the cross-correlation between the real and imaginary parts of quantum noise is very weak on the stationary properties when the laser system is operated far above threshold. 展开更多
关键词 two-mode laser correlated noises steady-state properties
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Ultra-low noise measurements of nanopore-based single molecular detection 被引量:1
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作者 Zhen Gu Huifeng Wang +1 位作者 Yi-Lun Ying Yi-Tao Long 《Science Bulletin》 SCIE EI CAS CSCD 2017年第18期1245-1250,共6页
Nanopore is an ultra-sensitive electrochemical technique for single molecular detection in confined space. To suppress the noise in detection of the weak current of nanopore, we investigated the influence of membrane ... Nanopore is an ultra-sensitive electrochemical technique for single molecular detection in confined space. To suppress the noise in detection of the weak current of nanopore, we investigated the influence of membrane capacitance and applied voltage on the noise of the current signal by model analysis, simulation and experiment. The obtained results demonstrated that membrane capacitance affects the noise by amplifying the noise of the applied voltage. Therefore, suppression of applied voltage noise is an efficient approach for reducing the noise in nanopore detection. Here, we developed an ultra-low noise instrument system for detecting the single molecule signal in nanopores. As demonstrated by nanopore experiments, the p-p noise of the developed system during the recording is reduced to 3.2B pA using the filter of 5 kHz. Therefore, the developed system could be applied in highly sensitive nanopore detection. 展开更多
关键词 Nanopore Membrane capacitance Current amplifier Signal amplifier and recording High current resolution
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Performance analysis of the silicon waveguide-based wavelength converter 被引量:2
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作者 王莹 桑新柱 +4 位作者 尹霄丽 苑金辉 Ashiq Hussaun 余重秀 忻向军 《Optoelectronics Letters》 EI 2011年第2期96-100,共5页
The conversion efficiency and noise figure (NF) of the silicon-on-insulator (SOI) waveguide-based wavelength converter are investigated with the coupled equations. The effects of the pump power, the nonlinear absorpti... The conversion efficiency and noise figure (NF) of the silicon-on-insulator (SOI) waveguide-based wavelength converter are investigated with the coupled equations. The effects of the pump power, the nonlinear absorption and the waveguide length on the conversion efficiency and noise figure are discussed. The conversion efficiency decreases with the increasing pump power and the noise figure is degraded due to the two-photon absorption (TPA) and the TPA-induced free-carrier absorption (FCA) at the higher pump power. With the increasing of the free carrier lifetime, the conversion efficiency will decrease and the noise figure will increase accordingly. The optimal waveguide length depends on the pump power and the free carrier lifetime. In practical applications, the high conversion efficiency and low noise figure can be achieved by choosing suitable parameters of the silicon waveguide. 展开更多
关键词 ABSORPTION Carrier lifetime Conversion efficiency Noise figure PUMPS Two photon processes
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THE EFFECT OF COUPLED FEEDBACK ON NOISE FILTERING IN SIGNAL TRANSDUCTION NETWORKS
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作者 Dengyu LIU Xiao CHANG +2 位作者 Zengrong LIU Luonan CHEN Ruiqi WANG 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2010年第5期942-950,共9页
Many interacting biomolecular components in cells form different positive or negative feedback loops. When biological signals transduce through cascades consisting of various loops they will be affected or even distor... Many interacting biomolecular components in cells form different positive or negative feedback loops. When biological signals transduce through cascades consisting of various loops they will be affected or even distorted. Especially, how to process various signals buried in various intrinsic and extrinsic noises is an important issue. This paper analyzes how the response time influences noise filtering ability and how to enhance the ability by coupling different feedback loops. A parameter to measure the response time of the signal transduction, i.e., τ0.9, and its relationship between the response time and noise filtering will be discussed. The authors show clearly that the longer the response time is, the better the ability to filter noises will be. Therefore, to enhance the ability to filter noises, the authors can prolong the response time by coupling different positive or negative feedback loops. The results provide a possible approach to enhance the ability to filter noises in larger biomolecular networks. 展开更多
关键词 Coupled feedback filtering noises response time signal cycle.
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