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结肠癌辅助化疗后存活的分子预测因子
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作者 李维碧 《中华医学信息导报》 2001年第13期20-21,共2页
关键词 结肠癌 辅助化疗 存活率 分子预测因子
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分子预测直肠癌新辅助放化疗后pCR的研究进展
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作者 李春波 刘彦龙 崔滨滨 《肿瘤学杂志》 CAS 2019年第12期1025-1030,共6页
局部晚期直肠癌(LARC)目前的基本治疗策略是新辅助放化疗(nCRT)和随后的全直肠系膜切除术(TME)。nCRT后的肿瘤消退在个体间差异显著,病理完全缓解(pCR)是LARC的预后因素。明确放化疗反应的预测因素有助于临床医生鉴别可能从多模式治疗... 局部晚期直肠癌(LARC)目前的基本治疗策略是新辅助放化疗(nCRT)和随后的全直肠系膜切除术(TME)。nCRT后的肿瘤消退在个体间差异显著,病理完全缓解(pCR)是LARC的预后因素。明确放化疗反应的预测因素有助于临床医生鉴别可能从多模式治疗中获益的患者,并在早期对其预后进行评估。本文结合近年的相关研究,探讨LARC在新辅助治疗后可能达到pCR的分子预测因子。 展开更多
关键词 直肠肿瘤 新辅助放化疗 病理完全缓解 分子预测因子
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Prediction of mass transfer coefficients in an asymmetric rotating disk contactor using effective diffusivity 被引量:2
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作者 Meisam Torab-Mostaedi Mehdi Asadollahzadeh Jaber Safdari 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第3期288-293,共6页
Mass transfer characteristics have been investigated in a 113 mm diameter asymmetric rotating disk contactor of the pilot plant scale for two different liquid–liquid systems. The effects of operating parameters inclu... Mass transfer characteristics have been investigated in a 113 mm diameter asymmetric rotating disk contactor of the pilot plant scale for two different liquid–liquid systems. The effects of operating parameters including rotor speed and continuous and dispersed phase velocities on the volumetric overall mass transfer coefficients are investigated. The results show that the mass transfer performance is strongly dependent on agitation rate and interfacial tension, but only slightly dependent on phase flow rates. In this study, effective diffusivity is used instead of molecular diffusivity in the Grober equation for estimation of dispersed phase overall mass transfer coefficient.The enhancement factor is determined experimentally and there from an empirical expression is derived for prediction of the enhancement factor as a function of Reynolds number. The predicted results compared to the experimental data show that the proposed correlation can efficiently predict the overall mass transfer coefficients in asymmetric rotating disk contactors. 展开更多
关键词 Asymmetric rotating disk contactor Mass transfer coefficient Enhancement factor Interfacial area Dispersed phase holdup
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