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分层涂布冷冻干燥工艺改善面膜中的咖啡因经皮透过
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作者 李和伟 魏国志 许飞飞 《香料香精化妆品》 CAS 2024年第2期77-82,共6页
为了改善面膜中咖啡因的经皮透过率,采用Hunter和星点设计-响应面法优化分层涂布冷冻干燥的关键工艺参数,并应用预测刻画器和设计空间确定工艺参数的可接受范围和最优值。确定涂布方式和涂布层数对咖啡因经皮透过有显著影响,涂布方式选... 为了改善面膜中咖啡因的经皮透过率,采用Hunter和星点设计-响应面法优化分层涂布冷冻干燥的关键工艺参数,并应用预测刻画器和设计空间确定工艺参数的可接受范围和最优值。确定涂布方式和涂布层数对咖啡因经皮透过有显著影响,涂布方式选择先涂布辅料基质,再涂布活性成分咖啡因。涂布层数、层厚和涂布速度的可接受范围:2~4层,0.5~1.2 mm和1~5 m/min,而3个参数的最优值分别为3层、0.5 mm和3 m/min。优化工艺后制备的3批面膜中咖啡因20 min透过率均超过10%。因此,优化后的分层涂布冷冻干燥工艺可大幅度提高面膜中咖啡因的经皮透过率。 展开更多
关键词 分层涂布冷冻干燥 咖啡因 面膜 经皮渗透 星点设计-响应面法
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壳聚糖/聚乙烯醇改善纸基材料的水蒸气和氧气阻隔性能研究 被引量:6
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作者 刘晓菲 张雪 +3 位作者 赵雨萌 程芸 胡小莉 张红杰 《中国造纸》 CAS 北大核心 2022年第5期17-24,共8页
研究了壳聚糖和聚乙烯醇在改善纸基材料水蒸气(极性气体)和氧气(非极性气体)阻隔性能上的应用效果,探讨了壳聚糖/聚乙烯醇不同质量比和不同复合方式(共混和分层)对纸基材料水蒸气和氧气阻隔性能、机械性能和涂层稳定性的影响。结果表明... 研究了壳聚糖和聚乙烯醇在改善纸基材料水蒸气(极性气体)和氧气(非极性气体)阻隔性能上的应用效果,探讨了壳聚糖/聚乙烯醇不同质量比和不同复合方式(共混和分层)对纸基材料水蒸气和氧气阻隔性能、机械性能和涂层稳定性的影响。结果表明,随着壳聚糖和聚乙烯醇质量比的降低,纸基材料的水蒸气阻隔性能逐渐增强,同时氧气阻隔性能逐渐降低;壳聚糖/聚乙烯醇分层涂布纸的水蒸气和氧气透过量均低于壳聚糖/聚乙烯醇共混涂布纸。当壳聚糖和聚乙烯醇的质量比为1∶1时,壳聚糖/聚乙烯醇分层涂布纸的水蒸气透过量和氧气透过量分别为9.36 g/(m^(2)·d)和31.93cm^(3)/(m^(2)·d);与纯壳聚糖涂布纸相比,水蒸气透过量降低了约92%,与壳聚糖/聚乙烯醇共混涂布纸相比,水蒸气透过量降低了约68%,氧气透过量降低了约67%。 展开更多
关键词 壳聚糖 聚乙烯醇 分层涂布 共混涂布 水蒸气阻隔 氧气阻隔
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Effect of reagent films on coupling relationship between glass surface and particles 被引量:1
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作者 李明 吴超 +1 位作者 刘一静 闫晖 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2012年第11期2799-2805,共7页
The experiments were conducted to investigate the behavior of airborne particles adhering to the glass slides which were coated by several reagent films. The results showed that the adhesion level could be significant... The experiments were conducted to investigate the behavior of airborne particles adhering to the glass slides which were coated by several reagent films. The results showed that the adhesion level could be significantly changed by the reagent films. There were no evident rules between the average size of particles and sampling time interval, the placing angle and reagent concentration. The average particle size on the surface coated by composite reagent (2-3 μm) was smaller than that on the single reagent coated surface, while the largest particle size (4-5 μm) was observed on the surface coated with the Tween 60. The experiment also demonstrated that the best adhesive performance was obtained on the surface which was coated with 0.5% SDBS and 0.5% fluorocarbon composite reagents. The experiment results indicated that each reagent had a certain optimum adhesive range to the particle. The composite reagents with different proportion of single reagents exhibited some particular physical and chemical properties, which could effectively change the adhesive performance between the solid surface and the particles. 展开更多
关键词 micro-particles ADHESION glass surface reagent film size distribution
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Effects of thickness and elastic modulus on stress condition of fatigue-resistant coating under rolling contact 被引量:4
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作者 朴钟宇 徐滨士 +1 位作者 王海斗 濮春欢 《Journal of Central South University》 SCIE EI CAS 2010年第5期899-905,共7页
The distribution and magnitude of surface substrates were investigated by finite element method and subsurface stresses of the (FEM). The models of coating single-layer sprayed-coatings on monolithic configurations ... The distribution and magnitude of surface substrates were investigated by finite element method and subsurface stresses of the (FEM). The models of coating single-layer sprayed-coatings on monolithic configurations with different thicknesses and elastic modulus ratios of coating to substrate were introduced, and the effects of thickness and elastic modulus ratio on the stresses were addressed. The calculation results show that the coating/substrate interface shear stress obviously decreases with increasing coating thickness, due to the location of the maximum shear stress moving away from the coating/substrate interface. At the same time, the magnitude of von Mises stress also declines in the case of thicker coatings. However, the high elastic modulus ratio results in extremely high maximum shear stress and the severe discontinuity of the von Mises stress curves, which leads to the intensive stress concentration on the coating/substrate interface. So the coating configurations with the larger coating thickness and lower difference of elastic modulus between coating and substrate exhibit excellent resistant performance of rolling contact fatigue (RCF). 展开更多
关键词 sprayed-coating thickness elastic modulus maximum stress von Mises stress finite element method
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Simulation of residual stresses and their effects on thermal barrier coating systems using finite element method 被引量:13
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作者 ZHU JianGuo CHEN Wei XIE HuiMin 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2015年第3期49-58,共10页
Thermal barrier coating(TBC)systems are widely used in industrial gas-turbine engines.However,premature failures have impaired the use of TBCs and cut down their lifetime,which requires a better understanding of their... Thermal barrier coating(TBC)systems are widely used in industrial gas-turbine engines.However,premature failures have impaired the use of TBCs and cut down their lifetime,which requires a better understanding of their failure mechanisms.In the present study,experimental studies of isothermal cycling are firstly carried out with the observation and estimation of microstructures.According to the experimental results,a finite element model is established for the analysis of stress perpendicular to the TBC/BC interface.Detailed residual stress distributions in TBC are obtained to reflect the influence of mechanical properties,oxidation,and interfacial roughness.The calculated results show that the maximum tensile stress concentration appears at the peak of TBC and continues to increase with thermal cycles.Because of the microstructural characteristics of plasma-sprayed TBCs,cracks initialize in tensile stress concentration(TSC)regions at the peaks of TBC and propagate along the TBC/BC interface resulting in the spallation of TBC.Also,the inclusion of creep is crucial to failure prediction and is more important than the inclusion of sintering in the simulation. 展开更多
关键词 residual stress failure mechanism finite element method thermal barrier coating
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