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超声对两相液体中分散水滴作用的动力学
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作者 王公正 李晓蒙 +2 位作者 莫润阳 叶明 杨厚禄 《西北大学学报(自然科学版)》 CAS CSCD 北大核心 2015年第6期957-964,共8页
基于空化泡运动方程的推导方法,推导出超声激励下两相液体中分散水滴简化模型的动力学方程,并用MATLAB数值模拟,得出超声作用下不同参量对水滴半径变化的影响。发现对于声速、液体密度及粘滞系数不同的分散相液体,声速对水滴半径变化几... 基于空化泡运动方程的推导方法,推导出超声激励下两相液体中分散水滴简化模型的动力学方程,并用MATLAB数值模拟,得出超声作用下不同参量对水滴半径变化的影响。发现对于声速、液体密度及粘滞系数不同的分散相液体,声速对水滴半径变化几乎没影响,液体密度和粘滞系数越小水滴半径增长幅度越大;静压越大水滴体积越不容易变化;水滴初始半径越小水滴半径变化幅度越大。对于确定的分散相液体,超声激励声压幅值越大或激励频率越低,水滴半径变化越大。通过对水滴半径变化的探索,为进一步研究超声对反相乳液作用机理提供理论依据。 展开更多
关键词 水滴半径 分散相液体 超声激励 液体静压
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A RP-HPLC method for determination of paclitaxel in its solid dispersion
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作者 刘祥瑞 吴科春 +2 位作者 张春晖 张烜 张强 《Journal of Chinese Pharmaceutical Sciences》 CAS 2007年第2期101-104,共4页
Aim To develop and validate a RP-HPLC method for the analysis of paclitaxel in a solid dispersion. Methods Paclitaxel and the internal standard norethisterone were separated using a Phenomenex ODS 3 column and monitor... Aim To develop and validate a RP-HPLC method for the analysis of paclitaxel in a solid dispersion. Methods Paclitaxel and the internal standard norethisterone were separated using a Phenomenex ODS 3 column and monitored at a wavelength at 227 nm. The isocratic mobile phase consisting of methanol-acetonitrile-water (40:30:30, V/V) was pumped at a flow-rate of 1.0 mL·min^-1. The dissolution studies were performed according to published studies. Results Under these chromatographic conditions, the calibration curve was linear in the range of 4-40 μg·mL ^-1 with the correlation coefficient of 0.9999. The mean recovery was 98.42 % (RSD = 1.19 %). At the 60 min time point, the dissolution of paclitaxel from the solid dispersion was nearly 100 %, however, the original form of paclitaxel was about 30 %. Conclusion The method was proven to be specific, accurate and precise for determining the dissolution of paclitaxel from solid dispersion. 展开更多
关键词 PACLITAXEL Solid dispersion RP-HPLC
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Dispersion of SiC particles in mechanical stirring of A356-SiC_p liquid
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作者 张君 张鹏 +1 位作者 杜云慧 姚莎莎 《Journal of Central South University》 SCIE EI CAS 2012年第6期1503-1507,共5页
In order to clarify the dispersion of SiC particles in straight-blade mechanical stirring of A1-SiCp liquid, the dispersion of SiC particles in A356-3.5% SiCp (volume fraction) liquid in a cylindrical crucible was s... In order to clarify the dispersion of SiC particles in straight-blade mechanical stirring of A1-SiCp liquid, the dispersion of SiC particles in A356-3.5% SiCp (volume fraction) liquid in a cylindrical crucible was studied. The relationship between rotating speed of stirrer and radial relative deviation of SiCp content in A356 liquid between the center and the periphery of crucible was established in the conditions of 35° for the gradient angle a of blade and 10 mm/s for the speed of moving up and down of stirrer. The results show that the radial relative deviation of SiCp content increases gradually with increasing the rotating speed of stirrer. When the rotating speed of stirrer is 200 r/min, the vertical dispersion of SiC particles in A356 liquid is even, but the radial relative deviation of SiCp content is 0.24. Consequently, the northomogeneous dispersion of SiC particles in A356 liquid is mainly resulted from the nonhomogeneous radial dispersion of SiC particles. 展开更多
关键词 DISPERSION straight-blade mechanical stirring A356-SiCp liquid
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Second-order moment modeling of dispersed two-phase turbulence——Part 1:USM,k-ε-k_p,and non-linear k-ε-k_p two-phase turbulence models 被引量:4
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作者 ZHOU LiXing 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2011年第6期1098-1107,共10页
Turbulent dispersed multiphase flows,including gas-particle,gas-droplet and bubble-liquid flows,are widely encountered in various engineering facilities.Modeling of two-phase turbulence,in particular the dispersed pha... Turbulent dispersed multiphase flows,including gas-particle,gas-droplet and bubble-liquid flows,are widely encountered in various engineering facilities.Modeling of two-phase turbulence,in particular the dispersed phase turbulence,is the key problem in the Eulerian-Eulerian simulation of practical dispersed multiphase flows.Although different models were developed and used,the experimental validation shows that they cannot always give satisfactory prediction results.In this paper the present author give a detailed review of the unified second-order moment (USM),k-k p and nonlinear k-k p two-phase turbulence models,proposed by him.The derivation and closure of these models are described in detail and the experimental validation and application of these models are extensively discussed. 展开更多
关键词 dispersed multiphase flows second-order moment model two-phase turbulence
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