In order to classify the minimal hepatic encephalopathy （MHE） patients from healthy controls, the independent component analysis （ICA） is used to generate the default mode network （DMN） from resting-state functi...In order to classify the minimal hepatic encephalopathy （MHE） patients from healthy controls, the independent component analysis （ICA） is used to generate the default mode network （DMN） from resting-state functional magnetic resonance imaging （fMRI）. Then a Bayesian voxel- wised method, graphical-model-based multivariate analysis （GAMMA）, is used to explore the associations between abnormal functional integration within DMN and clinical variable. Without any prior knowledge, five machine learning methods, namely, support vector machines （SVMs）, classification and regression trees （ CART ）, logistic regression, the Bayesian network, and C4.5, are applied to the classification. The functional integration patterns were alternative within DMN, which have the power to predict MHE with an accuracy of 98%. The GAMMA method generating functional integration patterns within DMN can become a simple, objective, and common imaging biomarker for detecting MIIE and can serve as a supplement to the existing diagnostic methods.展开更多
According to the basic emotional theory, the artificial emotional model based on the finite state machine（FSM） was presented. In finite state machine model of emotion, the emotional space included the basic emotiona...According to the basic emotional theory, the artificial emotional model based on the finite state machine（FSM） was presented. In finite state machine model of emotion, the emotional space included the basic emotional space and the multiple emotional spaces. The emotion-switching diagram was defined and transition fimction was developed using Markov chain and linear interpolation algorithm. The simulation model was built using Stateflow toolbox and Simulink toolbox based on the Matlab platform. And the model included three subsystems： the input one, the emotion one and the behavior one. In the emotional subsystem, the responses of different personalities to the external stimuli were described by defining personal space. This model takes states from an emotional space and updates its state depending on its current state and a state of its input （also a state-emotion）. The simulation model realizes the process of switching the emotion from the neutral state to other basic emotions. The simulation result is proved to correspond to emotion-switching law of human beings.展开更多
基金The National Natural Science Foundation of China(No.8123003481271739+2 种基金81501453)the Special Program of Medical Science of Jiangsu Province(No.BL2013029)the Natural Science Foundation of Jiangsu Province(No.BK20141342)
文摘In order to classify the minimal hepatic encephalopathy （MHE） patients from healthy controls, the independent component analysis （ICA） is used to generate the default mode network （DMN） from resting-state functional magnetic resonance imaging （fMRI）. Then a Bayesian voxel- wised method, graphical-model-based multivariate analysis （GAMMA）, is used to explore the associations between abnormal functional integration within DMN and clinical variable. Without any prior knowledge, five machine learning methods, namely, support vector machines （SVMs）, classification and regression trees （ CART ）, logistic regression, the Bayesian network, and C4.5, are applied to the classification. The functional integration patterns were alternative within DMN, which have the power to predict MHE with an accuracy of 98%. The GAMMA method generating functional integration patterns within DMN can become a simple, objective, and common imaging biomarker for detecting MIIE and can serve as a supplement to the existing diagnostic methods.
基金Project(2006AA04Z201) supported by the National High-Tech Research and Development Program of China
文摘According to the basic emotional theory, the artificial emotional model based on the finite state machine（FSM） was presented. In finite state machine model of emotion, the emotional space included the basic emotional space and the multiple emotional spaces. The emotion-switching diagram was defined and transition fimction was developed using Markov chain and linear interpolation algorithm. The simulation model was built using Stateflow toolbox and Simulink toolbox based on the Matlab platform. And the model included three subsystems： the input one, the emotion one and the behavior one. In the emotional subsystem, the responses of different personalities to the external stimuli were described by defining personal space. This model takes states from an emotional space and updates its state depending on its current state and a state of its input （also a state-emotion）. The simulation model realizes the process of switching the emotion from the neutral state to other basic emotions. The simulation result is proved to correspond to emotion-switching law of human beings.
