The possible collapse of different circumstances is derived with the help of the limit analysis theory.Analytical equations related to collapsing mechanisms in deep tunnel with smooth three-centered arc cross sections...The possible collapse of different circumstances is derived with the help of the limit analysis theory.Analytical equations related to collapsing mechanisms in deep tunnel with smooth three-centered arc cross sections are derived on the basis of Hoek-Brown failure criterion and upper bound limit analysis.The pore water pressure is considered in the analysis,as a work rate of external force.Numerical results about the shape of detaching curve and the weight of collapsing block per unit length corresponding to different parameters are obtained with the help of mathematical software.The shapes of collapsing block are drawn with respected to different parameters.Furthermore,the effects of different parameters on the shape of detaching curve and the weight of the collapsing block are discussed.展开更多
An minimum description length(MDL) criterion is proposed to choose a good partition for a bipartite network. A heuristic algorithm based on combination theory is presented to approach the optimal partition. As the heu...An minimum description length(MDL) criterion is proposed to choose a good partition for a bipartite network. A heuristic algorithm based on combination theory is presented to approach the optimal partition. As the heuristic algorithm automatically searches for the number of partitions, no user intervention is required. Finally, experiments are conducted on various datasets, and the results show that our method generates higher quality results than the state-of-art methods, cross-association and bipartite, recursively induced modules. Experiment results also show the good scalability of the proposed algorithm. The method is applied to traditional Chinese medicine(TCM) formula and Chinese herbal network whose community structure is not well known, and found that it detects significant and it is informative community division.展开更多
This paper considers a discrete-time Geo/G/1 queue under the Min(N, D)-policy in which the idle server resumes its service if either N customers accumulate in the system or the total backlog of the service times of ...This paper considers a discrete-time Geo/G/1 queue under the Min(N, D)-policy in which the idle server resumes its service if either N customers accumulate in the system or the total backlog of the service times of the waiting customers exceeds D, whichever occurs first (Min(N, D)-policy). By using renewal process theory and total probability decomposition technique, the authors study the transient and equilibrium properties of the queue length from the beginning of the arbitrary initial state, and obtain both the recursive expression of the z-transformation of tile transient queue length distribution and the recursive formula for calculating the steady state queue length at arbitrary time epoch n+. Meanwhile, the authors obtain the explicit expressions of the additional queue length distribution, l^trthermore, the important relations between the steady state queue length distributions at different time epochs n , n and n+ are also reported. Finally, the authors give numerical examples to illustrate the effect of system parameters on the steady state queue length distribution, and also show from numerical results that the expressions of the steady state queue length distribution is important in the system capacity design.展开更多
Royal jelly (R J)from honeybee has been widely used as a health promotion supplement.The major royal jelly proteins (MRJPs)have been identified as the functional component of RJ.However,the question of whether MRJPs h...Royal jelly (R J)from honeybee has been widely used as a health promotion supplement.The major royal jelly proteins (MRJPs)have been identified as the functional component of RJ.However,the question of whether MRJPs have anti-senescence activity for human cells remains.Human embryonic lung fibroblast (HFL-I)cells were cultured in media containing no MRJPs (A),MRJPs at 0.1mg/ml (B),0.2mg/ml (C),or 0.3mg/ml (D),or bovine serum albumin (BSA)at 0.2mg/ml (E).The mean population doubling levels of cells in media B,C,D,and E were increased by 12.4%,31.2%,24.0%,and 10.4%,respectively,compared with that in medium A.The cells in medium C also exhibited the highest relative proliferation activity,the lowest senescence,and the longest telomeres.Moreover, MRJPs up-regulated the expression of superoxide dismutase-1(SOD1)and down-regulated the expression of mammalian target of rapamycin (MTOR),catenin beta like-1(CTNNB1),and tumor protein p53(TP53).Raman spectra analysis showed that there were two unique bands related to DNA synthesis materials,amide carbonyl group vibrations and aromatic hydrogens.These results suggest that MRJPs possess anti-senescence activity for the HFL-I cell line,and provide new knowledge illustrating the molecular mechanism of MRJPs as anti-senescence factors.展开更多
基金Project(2013CB036004)supported by Basic Research Program of ChinaProjects(51378510,41302226)supported by National Natural Science Foundation of ChinaProject(2016zzts062)supported by Doctorial Innovation Foundation of Central South University,China
文摘The possible collapse of different circumstances is derived with the help of the limit analysis theory.Analytical equations related to collapsing mechanisms in deep tunnel with smooth three-centered arc cross sections are derived on the basis of Hoek-Brown failure criterion and upper bound limit analysis.The pore water pressure is considered in the analysis,as a work rate of external force.Numerical results about the shape of detaching curve and the weight of collapsing block per unit length corresponding to different parameters are obtained with the help of mathematical software.The shapes of collapsing block are drawn with respected to different parameters.Furthermore,the effects of different parameters on the shape of detaching curve and the weight of the collapsing block are discussed.
基金Projects(61363037,31071700)supported by the National Natural Science Foundation of ChinaProject(2011GXNSFD018025)supported by the Natural Science Key Foundation of Guangxi Province,ChinaProject(KYTZ201108)supported by the Development Foundation of Chengdu University of Information Technology,China
文摘An minimum description length(MDL) criterion is proposed to choose a good partition for a bipartite network. A heuristic algorithm based on combination theory is presented to approach the optimal partition. As the heuristic algorithm automatically searches for the number of partitions, no user intervention is required. Finally, experiments are conducted on various datasets, and the results show that our method generates higher quality results than the state-of-art methods, cross-association and bipartite, recursively induced modules. Experiment results also show the good scalability of the proposed algorithm. The method is applied to traditional Chinese medicine(TCM) formula and Chinese herbal network whose community structure is not well known, and found that it detects significant and it is informative community division.
基金supported by the National Natural Science Foundation of China under Grant Nos.71171138,71301111,71571127the Scientific Research Innovation&Application Foundation of Headmaster of Hexi University under Grant Nos.XZ2013-06,XZ2013-09
文摘This paper considers a discrete-time Geo/G/1 queue under the Min(N, D)-policy in which the idle server resumes its service if either N customers accumulate in the system or the total backlog of the service times of the waiting customers exceeds D, whichever occurs first (Min(N, D)-policy). By using renewal process theory and total probability decomposition technique, the authors study the transient and equilibrium properties of the queue length from the beginning of the arbitrary initial state, and obtain both the recursive expression of the z-transformation of tile transient queue length distribution and the recursive formula for calculating the steady state queue length at arbitrary time epoch n+. Meanwhile, the authors obtain the explicit expressions of the additional queue length distribution, l^trthermore, the important relations between the steady state queue length distributions at different time epochs n , n and n+ are also reported. Finally, the authors give numerical examples to illustrate the effect of system parameters on the steady state queue length distribution, and also show from numerical results that the expressions of the steady state queue length distribution is important in the system capacity design.
基金Project supported by the Science and Technology Project of Zhejiang Province(No.2017C32033)the National Natural Science Foundation of China(No.3127848)
文摘Royal jelly (R J)from honeybee has been widely used as a health promotion supplement.The major royal jelly proteins (MRJPs)have been identified as the functional component of RJ.However,the question of whether MRJPs have anti-senescence activity for human cells remains.Human embryonic lung fibroblast (HFL-I)cells were cultured in media containing no MRJPs (A),MRJPs at 0.1mg/ml (B),0.2mg/ml (C),or 0.3mg/ml (D),or bovine serum albumin (BSA)at 0.2mg/ml (E).The mean population doubling levels of cells in media B,C,D,and E were increased by 12.4%,31.2%,24.0%,and 10.4%,respectively,compared with that in medium A.The cells in medium C also exhibited the highest relative proliferation activity,the lowest senescence,and the longest telomeres.Moreover, MRJPs up-regulated the expression of superoxide dismutase-1(SOD1)and down-regulated the expression of mammalian target of rapamycin (MTOR),catenin beta like-1(CTNNB1),and tumor protein p53(TP53).Raman spectra analysis showed that there were two unique bands related to DNA synthesis materials,amide carbonyl group vibrations and aromatic hydrogens.These results suggest that MRJPs possess anti-senescence activity for the HFL-I cell line,and provide new knowledge illustrating the molecular mechanism of MRJPs as anti-senescence factors.