Carcinoma of the gastroesophageal junction(GEJ) is defined as carcinoma that crosses the GEJ line,irrespective of where the tumor epicenter is located.This group of cancer is rare but controversial.Based on study resu...Carcinoma of the gastroesophageal junction(GEJ) is defined as carcinoma that crosses the GEJ line,irrespective of where the tumor epicenter is located.This group of cancer is rare but controversial.Based on study results from the majority of epidemiologic and clinicopathologic investigations carried out in Western countries,this cancer is believed to arise from Barrett's esophagus(BE) and includes both distal esophageal and proximal gastric carcinomas because of similar characteristics in epidemiology,clinicopathology,and molecular pathobiology in relation to BE.As such,the most recent American Joint Committee on Cancer staging manual requires staging all GEJ carcinomas with the rule for esophageal adenocarcinoma(EA).This mandate has been challenged recently by the data from several studies carried out mainly in Chinese patients.The emerging evidence derivedfrom those studies suggests:(1) both BE and EA are uncommon in the Chinese population;(2) almost all GEJ cancers in Chinese arise in the proximal stomach and show the features of proximal gastric cancer,not those of EA;(3) application of the new cancer staging rule to GEJ cancer of Chinese patients cannot stratify patients' prognosis effectively;and(4) prognostic factors of GEJ cancer in Chinese are similar,but not identical,to those of EA.In conclusion,the recent evidence suggests that GEJ cancer in Chinese shows distinct clinicopathologic characteristics that are different from EA.Further investigations in molecular pathology may help illustrate the underlying pathogenesis mechanisms of this cancer in Chinese patients and better manage patients with this fatal disease.展开更多
As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of nois...As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of noise. Second, watershed algorithm is employed to provide initial regions. Third, regions are merged according to the information between the region and boundary. In the merger processing based on the region information, an adaptive threshold of the difference between the neighboring regions is used as the region merge criteria, which is based on the human visual character. In the merger processing on the boundary information, the gradient is used to judge the true boundary of the image to avoid merging the foreground with the background regions. Finally, post-process to the regions using mathematical morphology open and close filter is done to smooth object boundaries. The experimental results show that this method is very efficient.展开更多
Based on the network monitoring data and field investigations,the basic characteristics of the M S4.9 earthquake at the juncture of Gaoyou and Baoying in Jiangsu Province on July20,2012 have been introduced,and the fo...Based on the network monitoring data and field investigations,the basic characteristics of the M S4.9 earthquake at the juncture of Gaoyou and Baoying in Jiangsu Province on July20,2012 have been introduced,and the focal mechanism solutions have also been obtained.According to the regional tectonic features and site macroscopic survey,the occurrence of the earthquake was probably related to the Yangchacang-Sangshutou fault.Based on site survey data,both the evaluation criterion of seismic intensity of this region and the seismic intensity maps have been proposed.According to the damage characteristics of brick-concrete structure and brick-wood structure,the main reasons of serious damage for buildings are poor foundation conditions,low seismic bearing capacity,poor quality of construction and disrepair.Considering the differences of earthquake damage in the different regions,advice on accelerating the new rural construction,improving the resistance against earthquake disasters of rural residential areas and strengthening the seismogenic research on strong and moderate size earthquake is proposed,which will be possibly helpful for earthquake damage survey,prediction and prevention.展开更多
基金Supported by Science and Technology Development Project of the Nanjing City in China,No. ZKX05013,No. ZKX07011a special grant from the Nanjing Drum Tower Hospital in Nan-jing,China
文摘Carcinoma of the gastroesophageal junction(GEJ) is defined as carcinoma that crosses the GEJ line,irrespective of where the tumor epicenter is located.This group of cancer is rare but controversial.Based on study results from the majority of epidemiologic and clinicopathologic investigations carried out in Western countries,this cancer is believed to arise from Barrett's esophagus(BE) and includes both distal esophageal and proximal gastric carcinomas because of similar characteristics in epidemiology,clinicopathology,and molecular pathobiology in relation to BE.As such,the most recent American Joint Committee on Cancer staging manual requires staging all GEJ carcinomas with the rule for esophageal adenocarcinoma(EA).This mandate has been challenged recently by the data from several studies carried out mainly in Chinese patients.The emerging evidence derivedfrom those studies suggests:(1) both BE and EA are uncommon in the Chinese population;(2) almost all GEJ cancers in Chinese arise in the proximal stomach and show the features of proximal gastric cancer,not those of EA;(3) application of the new cancer staging rule to GEJ cancer of Chinese patients cannot stratify patients' prognosis effectively;and(4) prognostic factors of GEJ cancer in Chinese are similar,but not identical,to those of EA.In conclusion,the recent evidence suggests that GEJ cancer in Chinese shows distinct clinicopathologic characteristics that are different from EA.Further investigations in molecular pathology may help illustrate the underlying pathogenesis mechanisms of this cancer in Chinese patients and better manage patients with this fatal disease.
文摘As watershed algorithm suffers from over-segmentation problem, this paper presented an efficient method to resolve this problem. First, pre-process of the image using median filter is made to reduce the effect of noise. Second, watershed algorithm is employed to provide initial regions. Third, regions are merged according to the information between the region and boundary. In the merger processing based on the region information, an adaptive threshold of the difference between the neighboring regions is used as the region merge criteria, which is based on the human visual character. In the merger processing on the boundary information, the gradient is used to judge the true boundary of the image to avoid merging the foreground with the background regions. Finally, post-process to the regions using mathematical morphology open and close filter is done to smooth object boundaries. The experimental results show that this method is very efficient.
基金Supported by Key Project of Suzhou Municipal Government,China(No.2009-191)Key Project of Xuzhou Municipal Government,China(T(2009)009)
文摘Based on the network monitoring data and field investigations,the basic characteristics of the M S4.9 earthquake at the juncture of Gaoyou and Baoying in Jiangsu Province on July20,2012 have been introduced,and the focal mechanism solutions have also been obtained.According to the regional tectonic features and site macroscopic survey,the occurrence of the earthquake was probably related to the Yangchacang-Sangshutou fault.Based on site survey data,both the evaluation criterion of seismic intensity of this region and the seismic intensity maps have been proposed.According to the damage characteristics of brick-concrete structure and brick-wood structure,the main reasons of serious damage for buildings are poor foundation conditions,low seismic bearing capacity,poor quality of construction and disrepair.Considering the differences of earthquake damage in the different regions,advice on accelerating the new rural construction,improving the resistance against earthquake disasters of rural residential areas and strengthening the seismogenic research on strong and moderate size earthquake is proposed,which will be possibly helpful for earthquake damage survey,prediction and prevention.
