The design and implementation of a novel ADC architecture called ring-ADC for digital voltage regulator module controllers are presented. Based on the principle of voltage-controlled oscillators＇ transform from volta...The design and implementation of a novel ADC architecture called ring-ADC for digital voltage regulator module controllers are presented. Based on the principle of voltage-controlled oscillators＇ transform from voltage to frequency,the A/D conversion of ring-ADC achieves good linearity and precise calibration against process variations compared with the delay-line ADC. A differential pulse counting discriminator also helps decrease the power consumption of the ring-ADC. It is fabricated with a Chartered 0.35μm CMOS process, and the measurement results of the integral and differential nonlinearity performance are 0.92LSB and 1.2LSB respectively. The maximum gain error measured in ten sample chips is ± 3.85%. With sampling rate of 500kHz and when the voltage regulator module （VRM） works in steady state, the ring-ADC＇s average power consumption is 2.56mW. The ring-ADC is verified to meet the requirements for digital VRM controller application.展开更多
Nutrition data for older adults is an area that has few studies mainly in Brazil. Due to the importance to know the behavior of this age group, the aim of this study was to develop and validate a frequency food questi...Nutrition data for older adults is an area that has few studies mainly in Brazil. Due to the importance to know the behavior of this age group, the aim of this study was to develop and validate a frequency food questionnaire （FFQ） for older people in Brazil. It was considered a sample of 73 subjects from the city of Avar6, Sao Paulo, Brazil, and it was applied three 24-hour recalls and a FFQ developed for adults. Data from the three 24-hour recalls were transformed in nutrient intake as well as the data from FFQ. Statistical analysis was performed in order to get correlations between data from the mean of three 24-hour recalls and FFQ for some nutrients. It was found high correlations among them, concluding that the FFQ is valid to get nutrient intakes for older people.展开更多
Objective To facilitate the quality evaluation suitable for the unique characteristics of Chinese materia medica(CMM)by developing and implementing a novel approach known as the matching frequency statistical moment(M...Objective To facilitate the quality evaluation suitable for the unique characteristics of Chinese materia medica(CMM)by developing and implementing a novel approach known as the matching frequency statistical moment(MFSM)method.Methods This study established the MFSM method.To demonstrate its effectiveness,we applied this novel approach to analyze Danxi Granules(丹膝颗粒,DXG)and its constituent herbal materials.To begin with,the ultra-performance liquid chromatography(UPLC)was applied to obtain the chromatographic fingerprints of DXG and its constituent herbal materi-als.Next,the MFSM was leveraged to compress and integrate them into a new fingerprint with fewer analytical units.Then,we characterized the properties and variability of both the original and integrated fingerprints by calculating total quantum statistical moment(TQSM)parameters,information entropy and information amount,along with their relative standard deviation(RSD).Finally,we compared the TQSM parameters,information entropy and infor-mation amount,and their RSD between the traditional and novel fingerprints to validate the new analytical method.Results The chromatographic peaks of DXG and its 12 raw herbal materials were divided and integrated into peak families by the MFSM method.Before integration,the ranges of the peak number,three TQSM parameters,information entropy and information amount for each peak or peak family of UPLC fingerprints of DXG and its 12 raw herbal materials were 95.07−209.73,9390−183064μv·s,5.928−21.33 min,22.62−106.69 min^(2),4.230−6.539,and 50530−974186μv·s,respectively.After integration,the ranges of these parameters were 10.00−88.00,9390−183064μv·s,5.951−22.02 min,22.27−104.73 min^(2),2.223−5.277,and 38159−807200μv·s,respectively.Correspondingly,the RSD of all the aforementioned pa-rameters before integration were 2.12%−9.15%,6.04%−49.78%,1.15%−23.10%,3.97%−25.79%,1.49%−19.86%,and 6.64%−51.20%,respectively.However,after integration,they changed to 0.00%,6.04%−49.87%,1.73%−23.02%,3.84%−26.85%,1.17%−16.54%,and 6.40%−48.59%,respectively.The results demonstrated that in the newly integrated fingerprint,the analytical units of constituent herbal materials,information entropy and information amount were significantly reduced(P<0.05),while the TQSM parameters remained unchanged(P>0.05).Additionally,the RSD of the TQSM parameters,information entropy,and information amount didn’t show significant difference before and after integration(P>0.05),but the RSD of the number and area of the integrated analytical units significantly decreased(P<0.05).Conclusion The MFSM method could reduce the analytical units of constituent herbal mate-rials while maintain the properties and variability from their original fingerprint.Thus,it could serve as a feasible and reliable tool to reduce difficulties in analyzing multi-compo-nents within CMMs and facilitating the evaluation of their quality.展开更多
An existing Bayesian flood frequency analysis method is applied to quantile estimation for Pearson type three (P-III) probability distribution. The method couples prior and sample information under the framework of Ba...An existing Bayesian flood frequency analysis method is applied to quantile estimation for Pearson type three (P-III) probability distribution. The method couples prior and sample information under the framework of Bayesian formula, and the Markov Chain Monte Carlo (MCMC) sampling approach is used to estimate posterior distributions of parameters. Different from the original sampling algorithm (i.e. the important sampling) used in the existing approach, we use the adaptive metropolis (AM) sampling technique to generate a large number of parameter sets from Bayesian parameter posterior distributions in this paper. Consequently, the sampling distributions for quantiles or the hydrological design values are constructed. The sampling distributions of quantiles are estimated as the Bayesian method can provide not only various kinds of point estimators for quantiles, e.g. the expectation estimator, but also quantitative evaluation on uncertainties of these point estimators. Therefore, the Bayesian method brings more useful information to hydrological frequency analysis. As an example, the flood extreme sample series at a gauge are used to demonstrate the procedure of application.展开更多
文摘The design and implementation of a novel ADC architecture called ring-ADC for digital voltage regulator module controllers are presented. Based on the principle of voltage-controlled oscillators＇ transform from voltage to frequency,the A/D conversion of ring-ADC achieves good linearity and precise calibration against process variations compared with the delay-line ADC. A differential pulse counting discriminator also helps decrease the power consumption of the ring-ADC. It is fabricated with a Chartered 0.35μm CMOS process, and the measurement results of the integral and differential nonlinearity performance are 0.92LSB and 1.2LSB respectively. The maximum gain error measured in ten sample chips is ± 3.85%. With sampling rate of 500kHz and when the voltage regulator module （VRM） works in steady state, the ring-ADC＇s average power consumption is 2.56mW. The ring-ADC is verified to meet the requirements for digital VRM controller application.
文摘Nutrition data for older adults is an area that has few studies mainly in Brazil. Due to the importance to know the behavior of this age group, the aim of this study was to develop and validate a frequency food questionnaire （FFQ） for older people in Brazil. It was considered a sample of 73 subjects from the city of Avar6, Sao Paulo, Brazil, and it was applied three 24-hour recalls and a FFQ developed for adults. Data from the three 24-hour recalls were transformed in nutrient intake as well as the data from FFQ. Statistical analysis was performed in order to get correlations between data from the mean of three 24-hour recalls and FFQ for some nutrients. It was found high correlations among them, concluding that the FFQ is valid to get nutrient intakes for older people.
基金Natural Science Foundation of Hunan province(2022JJ30453 and 2024JJ6362)the Key Research and Development Program of Hunan Province(2022SK2014).
文摘Objective To facilitate the quality evaluation suitable for the unique characteristics of Chinese materia medica(CMM)by developing and implementing a novel approach known as the matching frequency statistical moment(MFSM)method.Methods This study established the MFSM method.To demonstrate its effectiveness,we applied this novel approach to analyze Danxi Granules(丹膝颗粒,DXG)and its constituent herbal materials.To begin with,the ultra-performance liquid chromatography(UPLC)was applied to obtain the chromatographic fingerprints of DXG and its constituent herbal materi-als.Next,the MFSM was leveraged to compress and integrate them into a new fingerprint with fewer analytical units.Then,we characterized the properties and variability of both the original and integrated fingerprints by calculating total quantum statistical moment(TQSM)parameters,information entropy and information amount,along with their relative standard deviation(RSD).Finally,we compared the TQSM parameters,information entropy and infor-mation amount,and their RSD between the traditional and novel fingerprints to validate the new analytical method.Results The chromatographic peaks of DXG and its 12 raw herbal materials were divided and integrated into peak families by the MFSM method.Before integration,the ranges of the peak number,three TQSM parameters,information entropy and information amount for each peak or peak family of UPLC fingerprints of DXG and its 12 raw herbal materials were 95.07−209.73,9390−183064μv·s,5.928−21.33 min,22.62−106.69 min^(2),4.230−6.539,and 50530−974186μv·s,respectively.After integration,the ranges of these parameters were 10.00−88.00,9390−183064μv·s,5.951−22.02 min,22.27−104.73 min^(2),2.223−5.277,and 38159−807200μv·s,respectively.Correspondingly,the RSD of all the aforementioned pa-rameters before integration were 2.12%−9.15%,6.04%−49.78%,1.15%−23.10%,3.97%−25.79%,1.49%−19.86%,and 6.64%−51.20%,respectively.However,after integration,they changed to 0.00%,6.04%−49.87%,1.73%−23.02%,3.84%−26.85%,1.17%−16.54%,and 6.40%−48.59%,respectively.The results demonstrated that in the newly integrated fingerprint,the analytical units of constituent herbal materials,information entropy and information amount were significantly reduced(P<0.05),while the TQSM parameters remained unchanged(P>0.05).Additionally,the RSD of the TQSM parameters,information entropy,and information amount didn’t show significant difference before and after integration(P>0.05),but the RSD of the number and area of the integrated analytical units significantly decreased(P<0.05).Conclusion The MFSM method could reduce the analytical units of constituent herbal mate-rials while maintain the properties and variability from their original fingerprint.Thus,it could serve as a feasible and reliable tool to reduce difficulties in analyzing multi-compo-nents within CMMs and facilitating the evaluation of their quality.
基金supported by the National Basic Research Pro-gram of China ("973" Program) (Grant No. 2007CB714104)the National Natural Science Foundation of China (Grant No. 50779013)
文摘An existing Bayesian flood frequency analysis method is applied to quantile estimation for Pearson type three (P-III) probability distribution. The method couples prior and sample information under the framework of Bayesian formula, and the Markov Chain Monte Carlo (MCMC) sampling approach is used to estimate posterior distributions of parameters. Different from the original sampling algorithm (i.e. the important sampling) used in the existing approach, we use the adaptive metropolis (AM) sampling technique to generate a large number of parameter sets from Bayesian parameter posterior distributions in this paper. Consequently, the sampling distributions for quantiles or the hydrological design values are constructed. The sampling distributions of quantiles are estimated as the Bayesian method can provide not only various kinds of point estimators for quantiles, e.g. the expectation estimator, but also quantitative evaluation on uncertainties of these point estimators. Therefore, the Bayesian method brings more useful information to hydrological frequency analysis. As an example, the flood extreme sample series at a gauge are used to demonstrate the procedure of application.
