This paper presents a case study on an ultra-deep diaphragm wall with a depth of 110 m constructed in Ningbo City. The in-situ application shows that using Bauer BC40 cutter machine in conjunction with cutter wheels s...This paper presents a case study on an ultra-deep diaphragm wall with a depth of 110 m constructed in Ningbo City. The in-situ application shows that using Bauer BC40 cutter machine in conjunction with cutter wheels specified for different strata would be qualified for constructing the 110 m diaphragm wall with high efficiency and precision given that the quality of slurry and poured concrete can be guaranteed. The ground settlement can be effectively controlled by using the overlapping construction method. Sliding failure as a whole characterized by pronounced lateral deformation is likely to occur in the upper muddy clay layer due to its high compressibility and sensitivity. In contrast, local collapse of trench walls tends to happen in the sandy silt strata. Furthermore, careful attention should be paid to sandy silt during the entire construction period as the vertical displacement of the sandy silt continues to develop even atter concrete pouring.展开更多
Objective:The present study was designed to evaluate the functional outcome of stapled transanal rectal resection(STARR)and to examine the relationship between the population density of the interstitial cells of Cajal...Objective:The present study was designed to evaluate the functional outcome of stapled transanal rectal resection(STARR)and to examine the relationship between the population density of the interstitial cells of Cajal(ICC)and the efficacy of the STARR operation in the management of obstructed defecation syndrome(ODS)patients.Methods:Full-thickness rectal samples were obtained from 50 ODS patients who underwent STARR.Samples were analysed using ICC immunohistochemistry.Clinical and functional parameters obtained with defecography and anorectal manometry were compared with 20 controls.Results:ICCs were significantly decreased in patients in the submucosal(SM),intramuscular(IM)andmyenteric(MY)regions when compared with the control group(P<0.05).The mean pre-operative Cleveland Constipation Score(CCS)was 24.264.1,whilst the CCS at 1,2,3,4 and 5 years post-operatively decreased significantly(P<0.05).At 3 post-operative years,58.3%(28/48)of the patients reported a favorable outcome(CCS10).On univariate analysis,the functional results were worse in those with pre-operative digitation(P=0.017),a decreased ICC-MY cell population(P=0.067),a higher resting anal canal pressure(P=0.039)and a higher rectal sensory threshold(P=0.073).Multivariate analysis showed the decreased ICC-MY cell population was an independent predictor for low unfavorable functional outcome(odds ratio=0.097,95%confidence interval:0.012–0.766).Conclusions:STARR achieved acceptable results at the cost of a slight deterioration over amore prolonged follow-up.Patients with a decreased ICC number in the rectal specimen showed an unfavorable functional outcome where pre-operative histological assessment of a full-thickness rectal samplemight predict for the functional outcome following STARR.展开更多
基金Funded by the National Basic Research Program of China(973 Program,No.2014CB046905)the National Natural Science Foundation of China(Grant Nos.41172249 and 51509186)+1 种基金the State Key Laboratory for Geomechanics and Deep Underground Engineering(No.SKLGDUEK1303)the funding provided by Zhuhai Da Heng Qin Company Limited(Grant No.SG25-2014-173B1)
文摘This paper presents a case study on an ultra-deep diaphragm wall with a depth of 110 m constructed in Ningbo City. The in-situ application shows that using Bauer BC40 cutter machine in conjunction with cutter wheels specified for different strata would be qualified for constructing the 110 m diaphragm wall with high efficiency and precision given that the quality of slurry and poured concrete can be guaranteed. The ground settlement can be effectively controlled by using the overlapping construction method. Sliding failure as a whole characterized by pronounced lateral deformation is likely to occur in the upper muddy clay layer due to its high compressibility and sensitivity. In contrast, local collapse of trench walls tends to happen in the sandy silt strata. Furthermore, careful attention should be paid to sandy silt during the entire construction period as the vertical displacement of the sandy silt continues to develop even atter concrete pouring.
基金supported by the National Natural Science Foundation of China(No.81603628),Medical Scientific Research Foundation of Guangdong Province,China(No.A2015180)and Sun Yat-Sen University Clinical Research 5010 Program(No.2017017).
文摘Objective:The present study was designed to evaluate the functional outcome of stapled transanal rectal resection(STARR)and to examine the relationship between the population density of the interstitial cells of Cajal(ICC)and the efficacy of the STARR operation in the management of obstructed defecation syndrome(ODS)patients.Methods:Full-thickness rectal samples were obtained from 50 ODS patients who underwent STARR.Samples were analysed using ICC immunohistochemistry.Clinical and functional parameters obtained with defecography and anorectal manometry were compared with 20 controls.Results:ICCs were significantly decreased in patients in the submucosal(SM),intramuscular(IM)andmyenteric(MY)regions when compared with the control group(P<0.05).The mean pre-operative Cleveland Constipation Score(CCS)was 24.264.1,whilst the CCS at 1,2,3,4 and 5 years post-operatively decreased significantly(P<0.05).At 3 post-operative years,58.3%(28/48)of the patients reported a favorable outcome(CCS10).On univariate analysis,the functional results were worse in those with pre-operative digitation(P=0.017),a decreased ICC-MY cell population(P=0.067),a higher resting anal canal pressure(P=0.039)and a higher rectal sensory threshold(P=0.073).Multivariate analysis showed the decreased ICC-MY cell population was an independent predictor for low unfavorable functional outcome(odds ratio=0.097,95%confidence interval:0.012–0.766).Conclusions:STARR achieved acceptable results at the cost of a slight deterioration over amore prolonged follow-up.Patients with a decreased ICC number in the rectal specimen showed an unfavorable functional outcome where pre-operative histological assessment of a full-thickness rectal samplemight predict for the functional outcome following STARR.
