AIM： TO evaluate quality of life （QOL） following Ivor Lewis, left transthoracic, and combined thoracoscopic/ laparoscopic esophagectomy in patients with esopha- geal cancer. METHODS： Ninety patients with esophagea...AIM： TO evaluate quality of life （QOL） following Ivor Lewis, left transthoracic, and combined thoracoscopic/ laparoscopic esophagectomy in patients with esopha- geal cancer. METHODS： Ninety patients with esophageal cancer were assigned to Ivor Lewis （/7 = 30）, combined thora- coscopic/laparoscopic （n = 30）, and left transthoracic （n = 30） esophagectomy groups. The QOL-core 30 questionnaire and the supplemental QOL-esophageal module 18 questionnaire for patients with esophageal cancer, both developed by the European Organization for Research and Treatment of Cancer, were used to evaluate patients＇ QOL from 1 wk before to 24 wk after surgery. RESULTS： A total of 324 questionnaires were collect- ed from 90 patients, 36 postoperative questionnaires were not completed because patients could not be contacted for follow-up visits. QOL declined markedly in all patients at 1 wk postoperatively： preoperative and 1-wk postoperative global QOL scores in the Ivor Lewis, combined thoracoscopic/laparoscopic, and left transthoracic groups were 80.8 ± 9.3 vs 32.0 ± 16.1 （P 〈 0.001）, 81.1±9.0 vs 53.3 ± 11.5 （P 〈 0.001）, and 83.6 ± 11.2 vs 46.4 ± 11.3 （P 〈 0.001）, respectively. Thereafter, QOL recovered gradually in all patients. Patients who underwent Ivor Lewis esophagectomy showed the most pronounced decline in QOL; global scores were lower in this group than in the combined thoracoscopic/laparoscopic （P 〈 0.001） and left trans- thoracic （P 〈 0.001） groups at 1 wk postoperatively and was not restored to the preoperative level at 24 wk postoperatively. QOL declined least in patients under- going combined thoracoscopic/laparoscopic esopha- gectomy, and most indices had recovered to preopera- tive levels at 24 wk postoperatively. In the Ivor Lewis and combined thoracoscopic/laparoscopic groups, pain and physical function scores were 78.9 ± 18.5 vs 57.8 ± 19.9 （P 〈 0.001） and 59.3 ± 16.1 vs 70.2 ± 19.2 （P = 0.02）, respectively, at 1 wk postoperatively and 26.1 ± 28.6 vs 9.5 ± 15.6 （P = 0.007） and 88.4 ± 10.5 vs 95.8 ± 7.3 （P = 0.003）, respectively, at 24 wk postop- eratively. Scores in the left transthoracic esophagecto- my group fell between those of the other two groups. CONCLUSION： Compared with Ivor Lewis and left transthoracic esophagectomies, combined thoraco- scopic/laparoscopic esophagectomy enables higher postoperative QOL, making it a preferable surgical ap- proach for esophageal cancer.展开更多
The readers of the prose The music of this sphere are usually carded away by the singing of various animals in nature, and for this reason, this article is always regarded as an ode to nature. The vivid description of...The readers of the prose The music of this sphere are usually carded away by the singing of various animals in nature, and for this reason, this article is always regarded as an ode to nature. The vivid description of the natural world evokes modem human beings＇ longing for the bosom of nature.展开更多
文摘AIM： TO evaluate quality of life （QOL） following Ivor Lewis, left transthoracic, and combined thoracoscopic/ laparoscopic esophagectomy in patients with esopha- geal cancer. METHODS： Ninety patients with esophageal cancer were assigned to Ivor Lewis （/7 = 30）, combined thora- coscopic/laparoscopic （n = 30）, and left transthoracic （n = 30） esophagectomy groups. The QOL-core 30 questionnaire and the supplemental QOL-esophageal module 18 questionnaire for patients with esophageal cancer, both developed by the European Organization for Research and Treatment of Cancer, were used to evaluate patients＇ QOL from 1 wk before to 24 wk after surgery. RESULTS： A total of 324 questionnaires were collect- ed from 90 patients, 36 postoperative questionnaires were not completed because patients could not be contacted for follow-up visits. QOL declined markedly in all patients at 1 wk postoperatively： preoperative and 1-wk postoperative global QOL scores in the Ivor Lewis, combined thoracoscopic/laparoscopic, and left transthoracic groups were 80.8 ± 9.3 vs 32.0 ± 16.1 （P 〈 0.001）, 81.1±9.0 vs 53.3 ± 11.5 （P 〈 0.001）, and 83.6 ± 11.2 vs 46.4 ± 11.3 （P 〈 0.001）, respectively. Thereafter, QOL recovered gradually in all patients. Patients who underwent Ivor Lewis esophagectomy showed the most pronounced decline in QOL; global scores were lower in this group than in the combined thoracoscopic/laparoscopic （P 〈 0.001） and left trans- thoracic （P 〈 0.001） groups at 1 wk postoperatively and was not restored to the preoperative level at 24 wk postoperatively. QOL declined least in patients under- going combined thoracoscopic/laparoscopic esopha- gectomy, and most indices had recovered to preopera- tive levels at 24 wk postoperatively. In the Ivor Lewis and combined thoracoscopic/laparoscopic groups, pain and physical function scores were 78.9 ± 18.5 vs 57.8 ± 19.9 （P 〈 0.001） and 59.3 ± 16.1 vs 70.2 ± 19.2 （P = 0.02）, respectively, at 1 wk postoperatively and 26.1 ± 28.6 vs 9.5 ± 15.6 （P = 0.007） and 88.4 ± 10.5 vs 95.8 ± 7.3 （P = 0.003）, respectively, at 24 wk postop- eratively. Scores in the left transthoracic esophagecto- my group fell between those of the other two groups. CONCLUSION： Compared with Ivor Lewis and left transthoracic esophagectomies, combined thoraco- scopic/laparoscopic esophagectomy enables higher postoperative QOL, making it a preferable surgical ap- proach for esophageal cancer.
文摘The readers of the prose The music of this sphere are usually carded away by the singing of various animals in nature, and for this reason, this article is always regarded as an ode to nature. The vivid description of the natural world evokes modem human beings＇ longing for the bosom of nature.
