Acoustical tweezer is a primary application of the radiation force of a sound field. When an ultrasound focused beam passes through a micro-particle, like a cell or living biological specimens, the particle will be ma...Acoustical tweezer is a primary application of the radiation force of a sound field. When an ultrasound focused beam passes through a micro-particle, like a cell or living biological specimens, the particle will be manipulated accurately without physical contact and invasion, due to the three-dimensional acoustical trapping force. Based on the Ray acoustics approach in the Mie regime, this work discusses the effects on the particle caused by Gaussian focused ultrasound, studies the acoustical trapping force of spherical Mie particles by ultrasound in any position, and analyzes the numerical calculation on the two-dimensional acoustical radiation force. This article also analyzes the conditions for the acoustical trapping phenomenon, and discusses the impact of the initial position and size of the particle on the magnitude of the acoustical radiation force. Furthermore, this paper considers the ultrasonic attenuation in a particle in the case of two-dimension, studies the attenuation's effects on the acoustical trapping force, and amends the calculation to the ordinary case with attenuation.展开更多
基金supported by the National Basic Research Program of China(Grant Nos. 2012CB921504, 2011CB707902)the National Natural Science Foundation of China(Grant No. 11274166)+3 种基金Fundamental Research Funds for the Central Universities(Grant Nos. 1113020403,1101020402)the State Key Laboratory of Acoustics, Chinese Academy of Sciences(Grant No. SKLA201207)the priority academic program development of Jiangsu Higher Education Institutions and SRF for ROCS, SEMproject of Interdisciplinary Center of Nanjing University
文摘Acoustical tweezer is a primary application of the radiation force of a sound field. When an ultrasound focused beam passes through a micro-particle, like a cell or living biological specimens, the particle will be manipulated accurately without physical contact and invasion, due to the three-dimensional acoustical trapping force. Based on the Ray acoustics approach in the Mie regime, this work discusses the effects on the particle caused by Gaussian focused ultrasound, studies the acoustical trapping force of spherical Mie particles by ultrasound in any position, and analyzes the numerical calculation on the two-dimensional acoustical radiation force. This article also analyzes the conditions for the acoustical trapping phenomenon, and discusses the impact of the initial position and size of the particle on the magnitude of the acoustical radiation force. Furthermore, this paper considers the ultrasonic attenuation in a particle in the case of two-dimension, studies the attenuation's effects on the acoustical trapping force, and amends the calculation to the ordinary case with attenuation.
