A new HPLC MS method to determine loratadine in human plasma was established. The method involved extracting drug with organic solvent under basic conditions. The samples were seperated by ODS column and determined ...A new HPLC MS method to determine loratadine in human plasma was established. The method involved extracting drug with organic solvent under basic conditions. The samples were seperated by ODS column and determined by mass detector. The calibration curve of loratadine was linear within the range of 0.4~100 ng·mL -1 with r=0.9995 . The recovery of this method was within 95%~104%, within day and between day RSD were less than 12%. To study the pharmacokinetics and relative bioavailability of loratadine tablets, two formulations of loratadine tablets were given to 18 healthy male volunteers according to a randomized 2 way cross over design. The C max , AUC 0 t and T max values of the two formulations were 51.89±20.18 ng·mL -1 and 52.48±22.35 ng·mL -1 ; 140.75±88.42 ng·h·mL -1 and 147.24±92.33 ng·h·mL -1 ; 0.81±0.35 h and 0.81±0.27 h respectively. Results from statistic analysis showed that there were no significant difference between the C max , AUC 0-t and T max values of the two formulations. The relative bioavailability of tablets I with respect to tablets II was 97%±13% from the AUC 0 t measurement. Bioequivalance was observed between the two tablets.展开更多
Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and f...Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and flavonoids. This article reviews the utilization of cassava leaf in the production of food, animal feed and antioxidants in recent years, analyzes the effects of anti-nutritional factors and extraction of an- tioxidative flavonoids on the utilization of cassava leaf, finally puts forward the main problems in the utilization of cassava leaf, to provide a theoretical basis for the ba- sic research of cassava leaf.展开更多
The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as t...The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.展开更多
Through research on the application of hydroviscous speed-adjusting clutch in belt conveyor, this paper concluded that hydroviscous speed-adjusting clutch has many advantages such as controllable start and stop, overl...Through research on the application of hydroviscous speed-adjusting clutch in belt conveyor, this paper concluded that hydroviscous speed-adjusting clutch has many advantages such as controllable start and stop, overload protection and multi-motor power equilibrium. But its theory when used in large power fan and pump could not meet the needs of belt conveyor soft-start operation. Focusing on the theo- retical analysis of the lubrication oil flow needed by the transmission procedure to form the oil-film. Put forward concrete calculation methods of lubrication flow and how to de- cide number of oil-films used in belt conveyor.展开更多
Accompanying the development of social economy,the land use model of mountainous area,typically eco-weak area,is changing gradually. Here the establishment of eco-friendly land use model in mountainous area,will pione...Accompanying the development of social economy,the land use model of mountainous area,typically eco-weak area,is changing gradually. Here the establishment of eco-friendly land use model in mountainous area,will pioneer the model of sustainable development in that area. Concerning Qianjiang District of Chongqing Municipality,huge change of land use model,mainly embodied in the unceasing increase of construction land and gradual decrease of agricultural use land,has taken place in recent years. To explore the eco-friendly land use model in mountainous area,Qianjiang District was chosen as the study object in the present study. Via analyzing the changes in land use model,we found that related eco-environment restrictive factors mainly regional climatic change,soil texture,hydrological environment as well as soil erosion and land degradation,etc. And based on these results,we further analyzed the effect of land use change on eco-environment and the factors restricting the maintenance of eco-environment and regional development,finally put forward the counter measures for balancing land use and co-environment in mountainous area. The results will be important for the development of social economy and eco-system construction in Qianjiang District.展开更多
How land-cover has been changed by human use over the last 300 years is oneof the five overarching questions guiding the Land-use/Cover Change (LUCC) Science/Research Plan.China has variety of historical documents pro...How land-cover has been changed by human use over the last 300 years is oneof the five overarching questions guiding the Land-use/Cover Change (LUCC) Science/Research Plan.China has variety of historical documents providing unique data superiority. So the characteristicsof farmland area in Shandong Province during the Qing Dynasty (1644-1911) are summarized firstly: 1)the rising trend of farmland area was striking; 2) farmland area had remarkable fluctuation; 3)farmland area per capita decreased dramatically; 4) wasteland reclamation index increased rapidly.Then, the driving forces of farmland area change are analyzed. It is concluded that natural andhuman factors are jointly influential. Among the driving forces, human dimensions are the mainfactors of farmland area change, which direct the general tendency of the changes mentioned above.And the natural factors influence the stability of farmland area as well. Variation of the naturalfactors would act as the major contributory factor to farmland area change during years or periodsof abrupt climatic changes, or during the intensive occurring periods of natural hazards. Besides,the passive aspects of human factors, such as war chaos also influenced the fluctuation of thefarmland area. This research indicates that it is feasible to study the land-use/cover change byChinese historical literatures, which has huge potential to provide a comprehensive picture of thegrowing dominance of human land-use and land-cover patterns that can be used in many global changeresearch projects.展开更多
Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administr...Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administration, econo- my, society and technology. Finally, existing problems and suggestions were pro- posed.展开更多
Cloud computing has emerged as a leading computing paradigm,with an increasing number of geographic information(geo-information) processing tasks now running on clouds.For this reason,geographic information system/rem...Cloud computing has emerged as a leading computing paradigm,with an increasing number of geographic information(geo-information) processing tasks now running on clouds.For this reason,geographic information system/remote sensing(GIS/RS) researchers rent more public clouds or establish more private clouds.However,a large proportion of these clouds are found to be underutilized,since users do not deal with big data every day.The low usage of cloud resources violates the original intention of cloud computing,which is to save resources by improving usage.In this work,a low-cost cloud computing solution was proposed for geo-information processing,especially for temporary processing tasks.The proposed solution adopted a hosted architecture and can be realized based on ordinary computers in a common GIS/RS laboratory.The usefulness and effectiveness of the proposed solution was demonstrated by using big data simplification as a case study.Compared to commercial public clouds and dedicated private clouds,the proposed solution is more low-cost and resource-saving,and is more suitable for GIS/RS applications.展开更多
On the basis of panel data from 29 provinces and cities throughout the country in 2006-2010, a research is made on factors influencing regional industrial solid waste comprehensive utilization ability through a regres...On the basis of panel data from 29 provinces and cities throughout the country in 2006-2010, a research is made on factors influencing regional industrial solid waste comprehensive utilization ability through a regression analysis method. Research result shows that a positive influence will generate on the comprehensive utilization ability of the industrial solid waste by three factors: regional industrial soldi waste treatment earning level, regional industrial soldi waste treatment investment level and regional industrial pollution treatment subsidy strength. And this thesis will propose suggestions from improving earning ability, enhartcing treatment investment and increasing government subsidy depending on result of empirical analysis.展开更多
It is of great significance for cleaner production to substitute bio-energy for fossil fuels in iron ore sintering. However, with the replacement ratio increasing, the consistency of heat front and flame front is brok...It is of great significance for cleaner production to substitute bio-energy for fossil fuels in iron ore sintering. However, with the replacement ratio increasing, the consistency of heat front and flame front is broken, and the thermal utilizing efficiency of fuel is reduced, which results in the decrease of yield and tumble index of sinter. Circulating flue gas to sintering bed as biochar replacing 40% coke, CO in flue gas can be reused so as to increase the thermal utilizing efficiency of fuels, and the consistency of two fronts is recovered for the circulating flue gas containing certain CO2, H2 O and lower O2, which contributes to increasing the maximum temperature, extending the high temperature duration time of sintering bed, and results in improving the output and quality of sinter. In the condition of circulating 40% flue gas, the sintering with biomass fuels is strengthened, and the sintering indexes with biomass fuel replacing 40% coke breeze are comparative to those of using coke breeze completely.展开更多
In Hungary a general agricultural census (AC) was carried out in 2000, followed in 2001 by the population and housing census. The two censuses had been designed separately. Originally the Hungarian Central Statistic...In Hungary a general agricultural census (AC) was carried out in 2000, followed in 2001 by the population and housing census. The two censuses had been designed separately. Originally the Hungarian Central Statistical Office (HCSO) did not plan the joint analysis of the data of the two censuses. Following the censuses users and researchers expressed the view that linking the data of the two databases would represent a value-added in the use of the data and the joint utilization of the databases of the two censuses was examined. The databases were matched and the aggregated handling of the information increased the potential for analysing both censuses and allowed further, more sophisticated investigations. By means of the databases of the two censuses, the first opportunity arose for matching the discrete data of the surveys. The precondition of the matching of the data was the conformity of the respective metadata of the two operations. ,,Private holding" and ,,dwelling-household" were the categories applicable as the smallest unit for the matching. The links between the private holdings and the households could be based on the identity of the persons living in the dwelling. The matching of the data required the use of individual identity codes. With the matching process used a joint database of the agricultural and population censuses was set up providing new approaches for gender disaggregated analysis. By using the linked database, the HCSO issued a series of publications on the households living in agricultural private holdings in the countryside. This presentation describes the method of matching the databases of the two censuses.展开更多
In the paper, the animal and plant diversity and its main characteristics in Pu'er City were summarized, and reviewedthe development and utilization of main special biological industry. The policies and research i...In the paper, the animal and plant diversity and its main characteristics in Pu'er City were summarized, and reviewedthe development and utilization of main special biological industry. The policies and research institutions on protection and utilization of biodiversity in Pu'er City were introduced. At the last, we analyzed the deficiencies in the conservation and utilization of biodiversity in Pu'er City and proposed the relevant measures to strengthen protection and utilization of biological diversity in the future.展开更多
The overexploitation of water resources has a substantial influence on their sustainable utilization and the ecological environment in a river basin. Quantification of the development and utilization of water resource...The overexploitation of water resources has a substantial influence on their sustainable utilization and the ecological environment in a river basin. Quantification of the development and utilization of water resources plays an important role in guiding the rational utilization of water resources. Based on this, this paper develops the concept of water resource utilization polarization(WRUP) in order to qualitatively analyze whether water resources are being overexploited in the process of utilization. An index model of WRUP was built to quantify the degree of water resources overexploitation. In addition, taking seven secondary basins of the Yellow River as examples, the available quantity, overdraft and polarization indexes of surface water and groundwater resources were calculated. The results show that there are 34.49×108 m3 of surface water available, which accounts for 56.21% of the total surface water volume. A total of 5.84×108 m3 of groundwater is available, which is 58.74% of the total groundwater resources. We also found that the water resources are heavily overexploited and that there is extensive polarization in the middle and lower reaches of the Yellow River. The highest polarization of water resources occurs from Lanzhou to Toudaoguai where the polarization index is 19.88 and from Longmen to Sanmenxia where it is 11.81. There is no polarization above Longyangxia or from Toudaoguai to Longmen. Overall, the polarization of water resources is 7.95 over the entire Yellow River area. These results provide a reference for the availability of water resources that can be used to determine the degree of overexploitation of the water resources in the Yellow River.展开更多
文摘A new HPLC MS method to determine loratadine in human plasma was established. The method involved extracting drug with organic solvent under basic conditions. The samples were seperated by ODS column and determined by mass detector. The calibration curve of loratadine was linear within the range of 0.4~100 ng·mL -1 with r=0.9995 . The recovery of this method was within 95%~104%, within day and between day RSD were less than 12%. To study the pharmacokinetics and relative bioavailability of loratadine tablets, two formulations of loratadine tablets were given to 18 healthy male volunteers according to a randomized 2 way cross over design. The C max , AUC 0 t and T max values of the two formulations were 51.89±20.18 ng·mL -1 and 52.48±22.35 ng·mL -1 ; 140.75±88.42 ng·h·mL -1 and 147.24±92.33 ng·h·mL -1 ; 0.81±0.35 h and 0.81±0.27 h respectively. Results from statistic analysis showed that there were no significant difference between the C max , AUC 0-t and T max values of the two formulations. The relative bioavailability of tablets I with respect to tablets II was 97%±13% from the AUC 0 t measurement. Bioequivalance was observed between the two tablets.
文摘Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and flavonoids. This article reviews the utilization of cassava leaf in the production of food, animal feed and antioxidants in recent years, analyzes the effects of anti-nutritional factors and extraction of an- tioxidative flavonoids on the utilization of cassava leaf, finally puts forward the main problems in the utilization of cassava leaf, to provide a theoretical basis for the ba- sic research of cassava leaf.
基金Supported by the Special Fund for Agro-scientific Research in the Public Interest(200904025)the Natural Science Foundation of Beijing(6122024)+1 种基金the Surface Project of the Science and Technology Development Program of Beijing Municipal Education Commission(KM200900005002)the Project for the Agricultural Science and Technology of Beijing(20110115)~~
文摘The recent progress on the proteins in edible insects was summarized, in- cluding the nutritional value, healthy value, food safety, extraction and content mea- surement of the proteins in edible insects, as well as the main development direc- tion of edible insect proteins. And we also pointed out the bottlenecks that restricted the development and utilization of proteins in edible insects, and proposed the prospect of the research, development and utilization of edible insects proteins.
文摘Through research on the application of hydroviscous speed-adjusting clutch in belt conveyor, this paper concluded that hydroviscous speed-adjusting clutch has many advantages such as controllable start and stop, overload protection and multi-motor power equilibrium. But its theory when used in large power fan and pump could not meet the needs of belt conveyor soft-start operation. Focusing on the theo- retical analysis of the lubrication oil flow needed by the transmission procedure to form the oil-film. Put forward concrete calculation methods of lubrication flow and how to de- cide number of oil-films used in belt conveyor.
文摘Accompanying the development of social economy,the land use model of mountainous area,typically eco-weak area,is changing gradually. Here the establishment of eco-friendly land use model in mountainous area,will pioneer the model of sustainable development in that area. Concerning Qianjiang District of Chongqing Municipality,huge change of land use model,mainly embodied in the unceasing increase of construction land and gradual decrease of agricultural use land,has taken place in recent years. To explore the eco-friendly land use model in mountainous area,Qianjiang District was chosen as the study object in the present study. Via analyzing the changes in land use model,we found that related eco-environment restrictive factors mainly regional climatic change,soil texture,hydrological environment as well as soil erosion and land degradation,etc. And based on these results,we further analyzed the effect of land use change on eco-environment and the factors restricting the maintenance of eco-environment and regional development,finally put forward the counter measures for balancing land use and co-environment in mountainous area. The results will be important for the development of social economy and eco-system construction in Qianjiang District.
文摘How land-cover has been changed by human use over the last 300 years is oneof the five overarching questions guiding the Land-use/Cover Change (LUCC) Science/Research Plan.China has variety of historical documents providing unique data superiority. So the characteristicsof farmland area in Shandong Province during the Qing Dynasty (1644-1911) are summarized firstly: 1)the rising trend of farmland area was striking; 2) farmland area had remarkable fluctuation; 3)farmland area per capita decreased dramatically; 4) wasteland reclamation index increased rapidly.Then, the driving forces of farmland area change are analyzed. It is concluded that natural andhuman factors are jointly influential. Among the driving forces, human dimensions are the mainfactors of farmland area change, which direct the general tendency of the changes mentioned above.And the natural factors influence the stability of farmland area as well. Variation of the naturalfactors would act as the major contributory factor to farmland area change during years or periodsof abrupt climatic changes, or during the intensive occurring periods of natural hazards. Besides,the passive aspects of human factors, such as war chaos also influenced the fluctuation of thefarmland area. This research indicates that it is feasible to study the land-use/cover change byChinese historical literatures, which has huge potential to provide a comprehensive picture of thegrowing dominance of human land-use and land-cover patterns that can be used in many global changeresearch projects.
文摘Land use plan serves as a leading role in land resource management, necessitating a powerful implementation guarantee system. The research concluded researches on guarantee system for land use plan from law, administration, econo- my, society and technology. Finally, existing problems and suggestions were pro- posed.
基金Project(41401434)supported by the National Natural Science Foundation of China
文摘Cloud computing has emerged as a leading computing paradigm,with an increasing number of geographic information(geo-information) processing tasks now running on clouds.For this reason,geographic information system/remote sensing(GIS/RS) researchers rent more public clouds or establish more private clouds.However,a large proportion of these clouds are found to be underutilized,since users do not deal with big data every day.The low usage of cloud resources violates the original intention of cloud computing,which is to save resources by improving usage.In this work,a low-cost cloud computing solution was proposed for geo-information processing,especially for temporary processing tasks.The proposed solution adopted a hosted architecture and can be realized based on ordinary computers in a common GIS/RS laboratory.The usefulness and effectiveness of the proposed solution was demonstrated by using big data simplification as a case study.Compared to commercial public clouds and dedicated private clouds,the proposed solution is more low-cost and resource-saving,and is more suitable for GIS/RS applications.
文摘On the basis of panel data from 29 provinces and cities throughout the country in 2006-2010, a research is made on factors influencing regional industrial solid waste comprehensive utilization ability through a regression analysis method. Research result shows that a positive influence will generate on the comprehensive utilization ability of the industrial solid waste by three factors: regional industrial soldi waste treatment earning level, regional industrial soldi waste treatment investment level and regional industrial pollution treatment subsidy strength. And this thesis will propose suggestions from improving earning ability, enhartcing treatment investment and increasing government subsidy depending on result of empirical analysis.
基金Projects(51174253,51304245) supported by National Natural Science Foundation of China
文摘It is of great significance for cleaner production to substitute bio-energy for fossil fuels in iron ore sintering. However, with the replacement ratio increasing, the consistency of heat front and flame front is broken, and the thermal utilizing efficiency of fuel is reduced, which results in the decrease of yield and tumble index of sinter. Circulating flue gas to sintering bed as biochar replacing 40% coke, CO in flue gas can be reused so as to increase the thermal utilizing efficiency of fuels, and the consistency of two fronts is recovered for the circulating flue gas containing certain CO2, H2 O and lower O2, which contributes to increasing the maximum temperature, extending the high temperature duration time of sintering bed, and results in improving the output and quality of sinter. In the condition of circulating 40% flue gas, the sintering with biomass fuels is strengthened, and the sintering indexes with biomass fuel replacing 40% coke breeze are comparative to those of using coke breeze completely.
文摘In Hungary a general agricultural census (AC) was carried out in 2000, followed in 2001 by the population and housing census. The two censuses had been designed separately. Originally the Hungarian Central Statistical Office (HCSO) did not plan the joint analysis of the data of the two censuses. Following the censuses users and researchers expressed the view that linking the data of the two databases would represent a value-added in the use of the data and the joint utilization of the databases of the two censuses was examined. The databases were matched and the aggregated handling of the information increased the potential for analysing both censuses and allowed further, more sophisticated investigations. By means of the databases of the two censuses, the first opportunity arose for matching the discrete data of the surveys. The precondition of the matching of the data was the conformity of the respective metadata of the two operations. ,,Private holding" and ,,dwelling-household" were the categories applicable as the smallest unit for the matching. The links between the private holdings and the households could be based on the identity of the persons living in the dwelling. The matching of the data required the use of individual identity codes. With the matching process used a joint database of the agricultural and population censuses was set up providing new approaches for gender disaggregated analysis. By using the linked database, the HCSO issued a series of publications on the households living in agricultural private holdings in the countryside. This presentation describes the method of matching the databases of the two censuses.
基金Supported by the National Natural Science Foundation of China(Grant 31360456,31060252)the Fund for Applied Basic Research of Yunnan Province(Grant2011FB050)+1 种基金the Fund for Reserve Talents of Young and Middle-aged Academic and Technical Leaders of Yunnan Province(Grant 2014HB027)the Fund for science and technology plan of Pu'er city(Science and technology bureau Pu'er city,No.2014-38)
文摘In the paper, the animal and plant diversity and its main characteristics in Pu'er City were summarized, and reviewedthe development and utilization of main special biological industry. The policies and research institutions on protection and utilization of biodiversity in Pu'er City were introduced. At the last, we analyzed the deficiencies in the conservation and utilization of biodiversity in Pu'er City and proposed the relevant measures to strengthen protection and utilization of biological diversity in the future.
基金National Natural Science Foundation of China(41371486)
文摘The overexploitation of water resources has a substantial influence on their sustainable utilization and the ecological environment in a river basin. Quantification of the development and utilization of water resources plays an important role in guiding the rational utilization of water resources. Based on this, this paper develops the concept of water resource utilization polarization(WRUP) in order to qualitatively analyze whether water resources are being overexploited in the process of utilization. An index model of WRUP was built to quantify the degree of water resources overexploitation. In addition, taking seven secondary basins of the Yellow River as examples, the available quantity, overdraft and polarization indexes of surface water and groundwater resources were calculated. The results show that there are 34.49×108 m3 of surface water available, which accounts for 56.21% of the total surface water volume. A total of 5.84×108 m3 of groundwater is available, which is 58.74% of the total groundwater resources. We also found that the water resources are heavily overexploited and that there is extensive polarization in the middle and lower reaches of the Yellow River. The highest polarization of water resources occurs from Lanzhou to Toudaoguai where the polarization index is 19.88 and from Longmen to Sanmenxia where it is 11.81. There is no polarization above Longyangxia or from Toudaoguai to Longmen. Overall, the polarization of water resources is 7.95 over the entire Yellow River area. These results provide a reference for the availability of water resources that can be used to determine the degree of overexploitation of the water resources in the Yellow River.