The purpose of this study was to investigate the effect of Laggera alata flavonen （LAF） on the inhibit- ing effect of human ovarian cancer HO-8910 cells proliferation and its possible mechanism in vitro. Methods： H...The purpose of this study was to investigate the effect of Laggera alata flavonen （LAF） on the inhibit- ing effect of human ovarian cancer HO-8910 cells proliferation and its possible mechanism in vitro. Methods： Human ovarian cancer HO-8910 cells were cultured in vitro. Inhibitory effect of LAF on the viability of HO-8910 cells was evaluated by the MTT assay. Apoptotic effect of different concentrations of LAF on HO-8910 cells was assessed by AO/EB staining and FCM with propidium iodide （PI） staining. Expression of proteins related to apoptosis was analyzed by Western blot. Results： LAF significantly inhibited the viability of HO-8910 cells proliferation in a dose-dependent and time-dependent manner, there were statistical significance compared with NS group （P 〈 0.05）, and the ICso was 4.28 pg/mL for 48 h. The cells treated with LAF showed typical morphological change and apoptotic rate increased by FCM in a dose-dependent, and there was notable dif- ference compared with NS group （P 〈 0.05）. Western blot showed that expression of Fas, caspase-8, tBid and Cyto-c proteins were up-regulated after treatment with LAF for 48 h in a concentration dependent. Conclusion： LAF could inhibit HO-8910 cells proliferation and induce apoptosis, which may be through the pathway of death receptor in vitro.展开更多
With the Pearson Correlation Coefficient measurement method, this paper studies the correlation between the various elements influencing the financial competitiveness of the fast fashion enterprieses and the long-term...With the Pearson Correlation Coefficient measurement method, this paper studies the correlation between the various elements influencing the financial competitiveness of the fast fashion enterprieses and the long-term financial stability, which shows that the financial resilience has the biggest correlation with the long-term financial stability, which is followed in sequence by financial management capacity, financial resources capacity, financial performance capacity, and financial activity capacity. This is due to the fact that such factors as financial solvency, financial operations, profitability, growth capacity and the ability to generate cash exert effect upon the long-term stability of the financial competitiveness.展开更多
The retirement age policy adjustment is again sharing the cost of the aging process, incentives to delay retirement life expectancy means that workers work longer. Developed by the elastic mechanism into retirement sy...The retirement age policy adjustment is again sharing the cost of the aging process, incentives to delay retirement life expectancy means that workers work longer. Developed by the elastic mechanism into retirement system framework, improve the flexibility of the retirement system, in curbing early retirement incentives to delay retirement, improve the elderly labor force participation rate, and achieved some success. The reform of the retirement system gradually into public view. To adapt to China＇s national conditions for the establishment of flexible retirement mechanism, western countries need to discuss flexible retirement system, in-depth analysis of the establishment of the special constraints flexible retirement mechanism, good theoretical advance preparation for retirement Mechanism.展开更多
文摘The purpose of this study was to investigate the effect of Laggera alata flavonen （LAF） on the inhibit- ing effect of human ovarian cancer HO-8910 cells proliferation and its possible mechanism in vitro. Methods： Human ovarian cancer HO-8910 cells were cultured in vitro. Inhibitory effect of LAF on the viability of HO-8910 cells was evaluated by the MTT assay. Apoptotic effect of different concentrations of LAF on HO-8910 cells was assessed by AO/EB staining and FCM with propidium iodide （PI） staining. Expression of proteins related to apoptosis was analyzed by Western blot. Results： LAF significantly inhibited the viability of HO-8910 cells proliferation in a dose-dependent and time-dependent manner, there were statistical significance compared with NS group （P 〈 0.05）, and the ICso was 4.28 pg/mL for 48 h. The cells treated with LAF showed typical morphological change and apoptotic rate increased by FCM in a dose-dependent, and there was notable dif- ference compared with NS group （P 〈 0.05）. Western blot showed that expression of Fas, caspase-8, tBid and Cyto-c proteins were up-regulated after treatment with LAF for 48 h in a concentration dependent. Conclusion： LAF could inhibit HO-8910 cells proliferation and induce apoptosis, which may be through the pathway of death receptor in vitro.
文摘With the Pearson Correlation Coefficient measurement method, this paper studies the correlation between the various elements influencing the financial competitiveness of the fast fashion enterprieses and the long-term financial stability, which shows that the financial resilience has the biggest correlation with the long-term financial stability, which is followed in sequence by financial management capacity, financial resources capacity, financial performance capacity, and financial activity capacity. This is due to the fact that such factors as financial solvency, financial operations, profitability, growth capacity and the ability to generate cash exert effect upon the long-term stability of the financial competitiveness.
文摘The retirement age policy adjustment is again sharing the cost of the aging process, incentives to delay retirement life expectancy means that workers work longer. Developed by the elastic mechanism into retirement system framework, improve the flexibility of the retirement system, in curbing early retirement incentives to delay retirement, improve the elderly labor force participation rate, and achieved some success. The reform of the retirement system gradually into public view. To adapt to China＇s national conditions for the establishment of flexible retirement mechanism, western countries need to discuss flexible retirement system, in-depth analysis of the establishment of the special constraints flexible retirement mechanism, good theoretical advance preparation for retirement Mechanism.
