We present a simple system of RoF communication based on electronic-optical frequency modulation（EO-FM） in the article. Optical system soflware-Optisystem5.0 was adopted. The results of software simulation showe tha...We present a simple system of RoF communication based on electronic-optical frequency modulation（EO-FM） in the article. Optical system soflware-Optisystem5.0 was adopted. The results of software simulation showe that the simplex - directional 5 Gbit/s data and UHF microwave of 24 GHz were successfully transmitted over 15 km single mode fiber with 0dBm transmitted power, dispersion is 17 ps/nm/km, attenuation is 0.25 dB/km.展开更多
An iterative learning model predictive control （ILMPC） technique is applied to a class of continuous/batch processes. Such processes are characterized by the operations of batch processes generating periodic strong ...An iterative learning model predictive control （ILMPC） technique is applied to a class of continuous/batch processes. Such processes are characterized by the operations of batch processes generating periodic strong disturbances to the continuous processes and traditional regulatory controllers are unable to eliminate these periodic disturbances. ILMPC integrates the feature of iterative learning control （ILC） handling repetitive signal and the flexibility of model predictive control （MPC）. By on-line monitoring the operation status of batch processes, an event-driven iterative learning algorithm for batch repetitive disturbances is initiated and the soft constraints are adjusted timely as the feasible region is away from the desired operating zone. The results of an industrial application show that the proposed ILMPC method is effective for a class of continuous/batch processes.展开更多
RNA interference (RNAi) is triggered by the presence of a double-stranded RNA (dsRNA), and results in the silencing of homologous gene expression through the specific degradation of an mRNA containing the same sequenc...RNA interference (RNAi) is triggered by the presence of a double-stranded RNA (dsRNA), and results in the silencing of homologous gene expression through the specific degradation of an mRNA containing the same sequence. dsRNAmediated RNAi can be used in a wide variety of eucaryotes to induce the sequence-specific inhibition of gene expression.Synthetic 21-23 nucleotide (nt) small interfering RNA (siRNA) with 2 nt 3' overhangs was recently found to mediate efficient sequence-specific mRNA degradation in mammalian cells. Here, we studied the effects of synthetic siRNA duplexes targeted to SARS coronavirus structural proteins E, M, and N in a cell culture system. Among total 26 siRNA duplexes, we obtained 3 siRNA duplexes which could sequence-specifically reduce target genes expression over 80％ at the concentration of 60 nM in Vero E6 cells. The downregulation effect was in correlation with the concentrations of the siRNA duplexes in a range of 0～60 nM. Our results also showed that many inactive siRNA duplexes may be brought to life simply by unpairing the 5' end of the antisense strands. Results suggest that siRNA is capable of inhibiting SARS coronavirus genes expression and thus may be a new therapeutic strategy for treatment of SARS.展开更多
Based on the concept of hydraulic dissipation of kinetic energy, a novel shock wave regulator, which is composed of a damper and an extemally triggered valve, is presented with thorough analyses on its working mechani...Based on the concept of hydraulic dissipation of kinetic energy, a novel shock wave regulator, which is composed of a damper and an extemally triggered valve, is presented with thorough analyses on its working mechanism. By establishing motion equations of each component of the regulator and simulating the dynamic behavior of the whole system, the shock wave regulator is demonstrated numerically to be able to change the width and amplitude of shock pulses. Prompt and easy adjustment can be achieved by changing the equivalent flow area of damping orifices and consequently the closing velocity of the flow area of a valve, which makes it applicable to different impact testing.展开更多
In the present paper, the effect of a small bottom tmdulation of the sea bed in the form of periodic bed form on the surface waves generated due to a rolling oscillation of a vertical barrier either partially immersed...In the present paper, the effect of a small bottom tmdulation of the sea bed in the form of periodic bed form on the surface waves generated due to a rolling oscillation of a vertical barrier either partially immersed or completely submerged in water of non uniform finite depth is investigated. A simplified perturbation technique involving a non dimensional parameter characterizing the smallness of the bottom deformation is applied to reduce the given boundary value problem to two independent boundary value problems upto first order. The first boundary value problem corresponds to the problem of water wave generation due to rolling oscillation of a vertical barrier either partially immersed or completely submerged in water of uniform finite depth. This is a well known problem whose solution is available in the literature. From the second boundary value problem, the first order correction to the wave amplitude at infinity is evaluated in terms of the shape function characterizing the bottom undulation, by employing Green＇s integral theorem. For a patch of sinusoidal ripples at the sea bottom, the first order correction to the wave amplitude at infinity for both the configuration of the barrier is then evaluated numerically and illustrated graphically for various values of the wave number. It is observed that resonant interaction of the wave generated, with the sinusoidal bottom undulation occurs when the ratio of twice the wavelength of the sinusoidal ripple to the wave length of waves generated, approaches unity. Also it is found that the resonance increases as the length of the barrier increases.展开更多
文摘We present a simple system of RoF communication based on electronic-optical frequency modulation（EO-FM） in the article. Optical system soflware-Optisystem5.0 was adopted. The results of software simulation showe that the simplex - directional 5 Gbit/s data and UHF microwave of 24 GHz were successfully transmitted over 15 km single mode fiber with 0dBm transmitted power, dispersion is 17 ps/nm/km, attenuation is 0.25 dB/km.
基金Supported by the National Creative Research Groups Science Foundation of China （60721062） and the National High Technology Research and Development Program of China （2007AA04Z162）.
文摘An iterative learning model predictive control （ILMPC） technique is applied to a class of continuous/batch processes. Such processes are characterized by the operations of batch processes generating periodic strong disturbances to the continuous processes and traditional regulatory controllers are unable to eliminate these periodic disturbances. ILMPC integrates the feature of iterative learning control （ILC） handling repetitive signal and the flexibility of model predictive control （MPC）. By on-line monitoring the operation status of batch processes, an event-driven iterative learning algorithm for batch repetitive disturbances is initiated and the soft constraints are adjusted timely as the feasible region is away from the desired operating zone. The results of an industrial application show that the proposed ILMPC method is effective for a class of continuous/batch processes.
基金supported by the Grant No.2003AA208215 from the National High Technology Programs of Chinathe Grant No.30270311 from the National Natural Science Foundation of China.
文摘RNA interference (RNAi) is triggered by the presence of a double-stranded RNA (dsRNA), and results in the silencing of homologous gene expression through the specific degradation of an mRNA containing the same sequence. dsRNAmediated RNAi can be used in a wide variety of eucaryotes to induce the sequence-specific inhibition of gene expression.Synthetic 21-23 nucleotide (nt) small interfering RNA (siRNA) with 2 nt 3' overhangs was recently found to mediate efficient sequence-specific mRNA degradation in mammalian cells. Here, we studied the effects of synthetic siRNA duplexes targeted to SARS coronavirus structural proteins E, M, and N in a cell culture system. Among total 26 siRNA duplexes, we obtained 3 siRNA duplexes which could sequence-specifically reduce target genes expression over 80％ at the concentration of 60 nM in Vero E6 cells. The downregulation effect was in correlation with the concentrations of the siRNA duplexes in a range of 0～60 nM. Our results also showed that many inactive siRNA duplexes may be brought to life simply by unpairing the 5' end of the antisense strands. Results suggest that siRNA is capable of inhibiting SARS coronavirus genes expression and thus may be a new therapeutic strategy for treatment of SARS.
基金the Naval Warship Research Department of Defense(No05131/1046)
文摘Based on the concept of hydraulic dissipation of kinetic energy, a novel shock wave regulator, which is composed of a damper and an extemally triggered valve, is presented with thorough analyses on its working mechanism. By establishing motion equations of each component of the regulator and simulating the dynamic behavior of the whole system, the shock wave regulator is demonstrated numerically to be able to change the width and amplitude of shock pulses. Prompt and easy adjustment can be achieved by changing the equivalent flow area of damping orifices and consequently the closing velocity of the flow area of a valve, which makes it applicable to different impact testing.
基金Supported by DST through the Research Project No.SR/SY/MS: 521/08
文摘In the present paper, the effect of a small bottom tmdulation of the sea bed in the form of periodic bed form on the surface waves generated due to a rolling oscillation of a vertical barrier either partially immersed or completely submerged in water of non uniform finite depth is investigated. A simplified perturbation technique involving a non dimensional parameter characterizing the smallness of the bottom deformation is applied to reduce the given boundary value problem to two independent boundary value problems upto first order. The first boundary value problem corresponds to the problem of water wave generation due to rolling oscillation of a vertical barrier either partially immersed or completely submerged in water of uniform finite depth. This is a well known problem whose solution is available in the literature. From the second boundary value problem, the first order correction to the wave amplitude at infinity is evaluated in terms of the shape function characterizing the bottom undulation, by employing Green＇s integral theorem. For a patch of sinusoidal ripples at the sea bottom, the first order correction to the wave amplitude at infinity for both the configuration of the barrier is then evaluated numerically and illustrated graphically for various values of the wave number. It is observed that resonant interaction of the wave generated, with the sinusoidal bottom undulation occurs when the ratio of twice the wavelength of the sinusoidal ripple to the wave length of waves generated, approaches unity. Also it is found that the resonance increases as the length of the barrier increases.
