A new role hierarchy model for RBAC (role-based access control) is presented and its features are illustrated through examples. Some new concepts such as private permission, public permission and special permission ar...A new role hierarchy model for RBAC (role-based access control) is presented and its features are illustrated through examples. Some new concepts such as private permission, public permission and special permission are introduced, based on the RRA97 model. Some new role-role inheriting forms such as normal inheritance, private inheritance, public inheritance and special-without inheritance are defined. Based on the ideas mentioned, the new role hierarchy model is formulated. It is easier and more comprehensible to describe role-role relationships through the new model than through the traditional ones. The new model is closer to the real world and its mechanism is more powerful. Particularly it is more suitable when used in large-scale role hierarchies.展开更多
A statistical multimodal background model was described for moving object detection in video surveillance. The solution to some of the problems such as illumination changes, initialization of model with moving objects...A statistical multimodal background model was described for moving object detection in video surveillance. The solution to some of the problems such as illumination changes, initialization of model with moving objects, and shadows suppression was provided. The background samples were chosen by thresholding inter-frame differences, and the Gaussian kernel density estimation was used to estimate the probability density function of background intensity. Pixel's neighbor information was considered to remove noise due to camera jitter and small motion in the scene. The hue-max-min-diff color information was used to detect and suppress moving cast shadows. The effectiveness of the proposed method in the foreground segmentation was demonstrated in the traffic surveillance application.展开更多
This paper first introduces attribute expression to describe attribute-based access control policy.Secondly,an access control policy enforcement language named A-XACML (attribute-XACML)is proposed,which is an extens...This paper first introduces attribute expression to describe attribute-based access control policy.Secondly,an access control policy enforcement language named A-XACML (attribute-XACML)is proposed,which is an extension of XACML.A-XACML is used as a simple,flexible way to express and enforce access control policies,especially attribute-based access control policy,in a variety of environments.The language and schema support include data types,functions,and combining logic which allow simple and complex policies to be defined.Finally,a system architecture and application case of user-role assignment is given to show how attribute expressions and A-XACML work in access control policy description and enforcement.The case shows that attribute expression and A-XACML can describe and enforce the complex access control policy in a simple and flexible way.展开更多
To describe and integrate various policies applied in different domains, the definition of the family of OntoRBAC based on the ontology of a general role-based access control (RBAC) policy is proposed, which can sup...To describe and integrate various policies applied in different domains, the definition of the family of OntoRBAC based on the ontology of a general role-based access control (RBAC) policy is proposed, which can support and extend the RBAC96 model. The uniform ontology-based description mechanism of secure policies is applied in OntoRBAC, which can be used to describe different secure policies in distributed systems and integrate policies in semantic level with upper concepts. In addition, some rules have been defined to reason within the OntoRBAC to extend the inference algorithms in ontology, which makes the system accommodate itself to RBAC policies better.展开更多
Most current catalyst preparation methods cause pollution to air, water and land with the use of hazardous chemicals, lengthy operation time, high energy input and excessive water usage. The development of green catal...Most current catalyst preparation methods cause pollution to air, water and land with the use of hazardous chemicals, lengthy operation time, high energy input and excessive water usage. The development of green catalyst preparation is necessary to prevent and eliminate waste from each step of the catalyst preparation. We summarize recent progress in the application of cold plasmas for green catalyst preparation. Cold plasma preparation can reduce the catalyst size, improve the dispersion and enhance catalyst-support interaction with the use of less or no hazardous chemicals. These improvements also lead to the enhancement of catalyst activity and stability. An alternative room temperature electron reduction with a non-hydrogen plasma as an electron source was developed for the reduction of noble metal ions in which no hazardous chemical reducing agent or hydrogen was needed. This creates many opportunities for the development of supported catalysts with heat sensitive substrates, including metal organic frameworks (MOFs), covalent organic framework(COFs), high surface area carbon, peptide, DNA, proteins and others. A novel floating metal catalyst on a water(or solution) surface has been established. Template removal using low temperature cold plasmas also leads to the formation of high surface area porous materials with characteristics that are normally only obtainable with high temperature calcination, but sintering can be avoided. Micro combustion has been developed for the removal of carbon template using cold plasma. This is promising for preparing many structured oxides in a simple way with no use of auxiliary chemicals. Many opportunities exist for the use of cold plasmas to make multi-metallic oxides. Some future development ideas are addressed.展开更多
Hybrid rice planting has been widely popularized and applied in the world. However, the high cost of seed production and the complicated procedures have become a bottleneck in the development of hybrid rice. The resea...Hybrid rice planting has been widely popularized and applied in the world. However, the high cost of seed production and the complicated procedures have become a bottleneck in the development of hybrid rice. The research progress on mixed sowing seed production techniques of hybrid rice was introduced from the aspects of rice resources creation, breeding, sowing seed technology research and cost benefit analysis. The production technology of the new mixed seeding combina- tion "Xinhunyou 6" was investigated, including the research and validation of benta- zon treatment period and dosage, mixing ratio of male and female parents, and the comparative test of different different sowing methods, which revealed that the mechanization technology of seed production of hybrid rice was mature and feasible and would be one of the most important development trend of technological devel- opment of hybrid rice production.展开更多
Aim To assess the potential effect of quercetin (QU), an natural plant estrogen, on CYP1A2, CYP2E1, and CYP3A2 activities in rat liver microsomes; and to identify the magnitude of inhibitory effect and the probable ...Aim To assess the potential effect of quercetin (QU), an natural plant estrogen, on CYP1A2, CYP2E1, and CYP3A2 activities in rat liver microsomes; and to identify the magnitude of inhibitory effect and the probable inhibitory mechanism of QU. Methods QU and specific substrate were concurrently incubated, with HPLC detection of the substrate metabolites for data analysis. The magnitude of inhibitory effect of QU on CYP3A2 was compared with those of ketoconazole (Ket) and erythromycin (Ery). The mechanism of its inhibitory effect on CYP3A2 and CYP2E1 was derived from Lineweaver-Burk plots. Results HPLC methods were in good linear relationship with r〉0.999 1. Relative standard deviations for intra-day and inter-day were〈8.4%. Recovery of each analyte in the concentrations studied was between 91.1% and 107.6 %. QU (up to 8 μmol·L^-1) showed potent induction to CYP1A2 (338.1% of the negative control)while inhibited CYP2E1 (49.2% of the negative control) and CYP3A2 (60.3% of the negative control) activity. The magnitude of inhibitory effect for QU on CYP3A2 was between those for Ket and Ery (Ket〉QU〉Ery). QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction. Conclusion HPLC assay has been validated with precision and accuracy. QU is an effective inhibitor of several CYP isoforms. It may cause relevant drug-drug interactions with CYP3A substrates. As a plant flavonoid, QU has potential not only in molecular advantage but also in CYP450 module capability for further application in cancer chemotherapy.展开更多
Segmental duplications on rice (Oryza sativa L.) chromosomes 8, 9, 11, and 12 were studied by examining the distributions of sequences resolved by 13 probes detecting multiple copies of DNA sequences. Four of the hyb...Segmental duplications on rice (Oryza sativa L.) chromosomes 8, 9, 11, and 12 were studied by examining the distributions of sequences resolved by 13 probes detecting multiple copies of DNA sequences. Four of the hybridization bands detected by a repetitive sequence probe, rTRS, were mapped to the ends of all the four chromosomes. Two or three of the bands detected by each of the other 12 probes were also mapped to different chromosomes. The bands detected by the same probe usually occurred in similar locations of different chromosomes. Loci detected by different DNA probes were often similarly arranged on different chromosomes. Chromosomes 8 and 9 showed colinearity of marker loci arrangement indicating a possible common origin. A segment on chromosome 9 was also very similar to the previously reported duplicated fragments on the ends of chromosomes 11 and 12 which were also detected in this study, indicating a likely common origin. Moreover, the various degrees of distributional similarity of the segments suggest a complex relationship among the chromosomes in the evolution of the rice genome. These results support the proposition that chromosome duplication and diversification may be a mechanism for the origin and evolution of the chromosomes in the rice genome.展开更多
Aim An HPLC method for analyzing eleutheroside B (ELU B) and eleutheroside E(ELU E) , two of the main active substances of Acanthopanax preparations were studied. Methods Thesamples were analyzed on a kromasil ODS col...Aim An HPLC method for analyzing eleutheroside B (ELU B) and eleutheroside E(ELU E) , two of the main active substances of Acanthopanax preparations were studied. Methods Thesamples were analyzed on a kromasil ODS column with water-acetonitrile as a gradient mobile phase.The flow rate was 0.8 mL·min^(-1) and detecting wavelengths were 206 nm for ELU B, 220 nm for ELUE, solid phase extraction (SPE) and internal standard-salicin were selected. Results The recoveriesof Acanthopanax tablets and injection were 90.4% - 96.8% and 96.4% - 99.8% for ELU B, 87.7% -93.3%and 95.7% - 98.5% for ELU E, respectively. The linear ranges were 4.45 - 22.25 μg· mL^(-1) (r =0.999 8) and 5.11 - 25.55 μg·mL^(-1) ( r = 0.999 7) respectively. Conclusion This method can savethe time for cleaning the chromatographic system and improve sensitivity for Acanthopanaxpreparations , thus providing a way to evaluate the quality of Acanthopanax preparations.展开更多
Aim To establish a reversed-phase liquid chromatographic (LC) method forsimultaneous determination of tetramethylpyrazine (TMP) and aspirin in a new compound formulation.Methods Chromatographic separation of the two d...Aim To establish a reversed-phase liquid chromatographic (LC) method forsimultaneous determination of tetramethylpyrazine (TMP) and aspirin in a new compound formulation.Methods Chromatographic separation of the two drugs was achieved on a Diamonsil C_(18) column, usinga binary mixture of methanol-1.5% acetic acid (35:65, V/V, pH = 3.1) as mobile phase at a flow rateof 1.0 mL·min^(-1). Results Separation was completed in less than 12 min. Benzoic acid was used asthe internal standard. Recoveries at levels corresponding to 80 % to 120 % of the label claim ofthe formulation ranged from 99.6 to 100.3 % for aspirin and from 99.9 to 101.3% for TMP. The linearrange was 12.6 - 150.9 μg·mL^(-1)(r= 0.9997, n = 5) for aspirin and 25.0- 300.0 μg·mL^(-1) (r =0.9999, n = 5) for TMP. Conclusion The method developed can be used for the simultaneousdetermination of TMP and aspirin in pharmaceutical preparations.展开更多
文摘A new role hierarchy model for RBAC (role-based access control) is presented and its features are illustrated through examples. Some new concepts such as private permission, public permission and special permission are introduced, based on the RRA97 model. Some new role-role inheriting forms such as normal inheritance, private inheritance, public inheritance and special-without inheritance are defined. Based on the ideas mentioned, the new role hierarchy model is formulated. It is easier and more comprehensible to describe role-role relationships through the new model than through the traditional ones. The new model is closer to the real world and its mechanism is more powerful. Particularly it is more suitable when used in large-scale role hierarchies.
文摘A statistical multimodal background model was described for moving object detection in video surveillance. The solution to some of the problems such as illumination changes, initialization of model with moving objects, and shadows suppression was provided. The background samples were chosen by thresholding inter-frame differences, and the Gaussian kernel density estimation was used to estimate the probability density function of background intensity. Pixel's neighbor information was considered to remove noise due to camera jitter and small motion in the scene. The hue-max-min-diff color information was used to detect and suppress moving cast shadows. The effectiveness of the proposed method in the foreground segmentation was demonstrated in the traffic surveillance application.
基金The National High Technology Research and Development Program of China(863Program)(No.2007AA01Z445)
文摘This paper first introduces attribute expression to describe attribute-based access control policy.Secondly,an access control policy enforcement language named A-XACML (attribute-XACML)is proposed,which is an extension of XACML.A-XACML is used as a simple,flexible way to express and enforce access control policies,especially attribute-based access control policy,in a variety of environments.The language and schema support include data types,functions,and combining logic which allow simple and complex policies to be defined.Finally,a system architecture and application case of user-role assignment is given to show how attribute expressions and A-XACML work in access control policy description and enforcement.The case shows that attribute expression and A-XACML can describe and enforce the complex access control policy in a simple and flexible way.
基金The National Natural Science Foundation of China(No60403027)
文摘To describe and integrate various policies applied in different domains, the definition of the family of OntoRBAC based on the ontology of a general role-based access control (RBAC) policy is proposed, which can support and extend the RBAC96 model. The uniform ontology-based description mechanism of secure policies is applied in OntoRBAC, which can be used to describe different secure policies in distributed systems and integrate policies in semantic level with upper concepts. In addition, some rules have been defined to reason within the OntoRBAC to extend the inference algorithms in ontology, which makes the system accommodate itself to RBAC policies better.
基金supported by the National Natural Science Foundation of China(20990223 and 21476157)~~
文摘Most current catalyst preparation methods cause pollution to air, water and land with the use of hazardous chemicals, lengthy operation time, high energy input and excessive water usage. The development of green catalyst preparation is necessary to prevent and eliminate waste from each step of the catalyst preparation. We summarize recent progress in the application of cold plasmas for green catalyst preparation. Cold plasma preparation can reduce the catalyst size, improve the dispersion and enhance catalyst-support interaction with the use of less or no hazardous chemicals. These improvements also lead to the enhancement of catalyst activity and stability. An alternative room temperature electron reduction with a non-hydrogen plasma as an electron source was developed for the reduction of noble metal ions in which no hazardous chemical reducing agent or hydrogen was needed. This creates many opportunities for the development of supported catalysts with heat sensitive substrates, including metal organic frameworks (MOFs), covalent organic framework(COFs), high surface area carbon, peptide, DNA, proteins and others. A novel floating metal catalyst on a water(or solution) surface has been established. Template removal using low temperature cold plasmas also leads to the formation of high surface area porous materials with characteristics that are normally only obtainable with high temperature calcination, but sintering can be avoided. Micro combustion has been developed for the removal of carbon template using cold plasma. This is promising for preparing many structured oxides in a simple way with no use of auxiliary chemicals. Many opportunities exist for the use of cold plasmas to make multi-metallic oxides. Some future development ideas are addressed.
基金Supported by the National High-tech R&D Program(863 Program)(2014AA10A603)the Key Science and Technology Program during the"13thFive Year Plan"of Anhui Province(1604a0702008)+1 种基金the Special Fund for Agro-scientific Research in the Public Interest(201503130)the Project for the Team of Science and Technology Innovation of Anhui Academy of Agricultural Sciences(15C0108)~~
文摘Hybrid rice planting has been widely popularized and applied in the world. However, the high cost of seed production and the complicated procedures have become a bottleneck in the development of hybrid rice. The research progress on mixed sowing seed production techniques of hybrid rice was introduced from the aspects of rice resources creation, breeding, sowing seed technology research and cost benefit analysis. The production technology of the new mixed seeding combina- tion "Xinhunyou 6" was investigated, including the research and validation of benta- zon treatment period and dosage, mixing ratio of male and female parents, and the comparative test of different different sowing methods, which revealed that the mechanization technology of seed production of hybrid rice was mature and feasible and would be one of the most important development trend of technological devel- opment of hybrid rice production.
文摘Aim To assess the potential effect of quercetin (QU), an natural plant estrogen, on CYP1A2, CYP2E1, and CYP3A2 activities in rat liver microsomes; and to identify the magnitude of inhibitory effect and the probable inhibitory mechanism of QU. Methods QU and specific substrate were concurrently incubated, with HPLC detection of the substrate metabolites for data analysis. The magnitude of inhibitory effect of QU on CYP3A2 was compared with those of ketoconazole (Ket) and erythromycin (Ery). The mechanism of its inhibitory effect on CYP3A2 and CYP2E1 was derived from Lineweaver-Burk plots. Results HPLC methods were in good linear relationship with r〉0.999 1. Relative standard deviations for intra-day and inter-day were〈8.4%. Recovery of each analyte in the concentrations studied was between 91.1% and 107.6 %. QU (up to 8 μmol·L^-1) showed potent induction to CYP1A2 (338.1% of the negative control)while inhibited CYP2E1 (49.2% of the negative control) and CYP3A2 (60.3% of the negative control) activity. The magnitude of inhibitory effect for QU on CYP3A2 was between those for Ket and Ery (Ket〉QU〉Ery). QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction. Conclusion HPLC assay has been validated with precision and accuracy. QU is an effective inhibitor of several CYP isoforms. It may cause relevant drug-drug interactions with CYP3A substrates. As a plant flavonoid, QU has potential not only in molecular advantage but also in CYP450 module capability for further application in cancer chemotherapy.
文摘Segmental duplications on rice (Oryza sativa L.) chromosomes 8, 9, 11, and 12 were studied by examining the distributions of sequences resolved by 13 probes detecting multiple copies of DNA sequences. Four of the hybridization bands detected by a repetitive sequence probe, rTRS, were mapped to the ends of all the four chromosomes. Two or three of the bands detected by each of the other 12 probes were also mapped to different chromosomes. The bands detected by the same probe usually occurred in similar locations of different chromosomes. Loci detected by different DNA probes were often similarly arranged on different chromosomes. Chromosomes 8 and 9 showed colinearity of marker loci arrangement indicating a possible common origin. A segment on chromosome 9 was also very similar to the previously reported duplicated fragments on the ends of chromosomes 11 and 12 which were also detected in this study, indicating a likely common origin. Moreover, the various degrees of distributional similarity of the segments suggest a complex relationship among the chromosomes in the evolution of the rice genome. These results support the proposition that chromosome duplication and diversification may be a mechanism for the origin and evolution of the chromosomes in the rice genome.
文摘Aim An HPLC method for analyzing eleutheroside B (ELU B) and eleutheroside E(ELU E) , two of the main active substances of Acanthopanax preparations were studied. Methods Thesamples were analyzed on a kromasil ODS column with water-acetonitrile as a gradient mobile phase.The flow rate was 0.8 mL·min^(-1) and detecting wavelengths were 206 nm for ELU B, 220 nm for ELUE, solid phase extraction (SPE) and internal standard-salicin were selected. Results The recoveriesof Acanthopanax tablets and injection were 90.4% - 96.8% and 96.4% - 99.8% for ELU B, 87.7% -93.3%and 95.7% - 98.5% for ELU E, respectively. The linear ranges were 4.45 - 22.25 μg· mL^(-1) (r =0.999 8) and 5.11 - 25.55 μg·mL^(-1) ( r = 0.999 7) respectively. Conclusion This method can savethe time for cleaning the chromatographic system and improve sensitivity for Acanthopanaxpreparations , thus providing a way to evaluate the quality of Acanthopanax preparations.
文摘Aim To establish a reversed-phase liquid chromatographic (LC) method forsimultaneous determination of tetramethylpyrazine (TMP) and aspirin in a new compound formulation.Methods Chromatographic separation of the two drugs was achieved on a Diamonsil C_(18) column, usinga binary mixture of methanol-1.5% acetic acid (35:65, V/V, pH = 3.1) as mobile phase at a flow rateof 1.0 mL·min^(-1). Results Separation was completed in less than 12 min. Benzoic acid was used asthe internal standard. Recoveries at levels corresponding to 80 % to 120 % of the label claim ofthe formulation ranged from 99.6 to 100.3 % for aspirin and from 99.9 to 101.3% for TMP. The linearrange was 12.6 - 150.9 μg·mL^(-1)(r= 0.9997, n = 5) for aspirin and 25.0- 300.0 μg·mL^(-1) (r =0.9999, n = 5) for TMP. Conclusion The method developed can be used for the simultaneousdetermination of TMP and aspirin in pharmaceutical preparations.