目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组...目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组给予祛湿清热针刺疗法治疗。治疗2周后,观察比较两组患者临床疗效、不良反应情况,治疗前后中医证候评分、湿疹面积及严重度指数(Eczema area and severity index,EASI)评分、视觉模拟评分法(Visual pain scale,VAS)评分、实验室检查指标[嗜酸性粒细胞(Eosinophil,EOS)、白细胞介素-17(Interleukin-17,IL-17)、干扰素-γ(Interferon,IFN-γ)、芳香烃受体(Aromatic hydrocarbon receptor,AhR)]、皮肤生理功能指标。结果治疗后治疗组临床总有效率97.44%(38/39)明显高于对照组82.05%(32/39),差异有统计学意义(P<0.05)。治疗后两组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者EASI、VAS评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组EASI、VAS评分均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者AhR、IL-17、IFN-γ、EOS水平均较治疗前降低,差异有统计学意义(P<0.05);且治疗组AhR、IL-17、IFN-γ、EOS水平均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者皮肤生理功能指标较治疗前升高,差异有统计学意义(P<0.05);且治疗组皮肤生理功能指标较对照组明显升高,差异有统计学意义(P<0.05)。治疗期间,治疗组不良反应发生率7.69%(3/39)与对照组17.95%(7/39)比较,差异无统计学意义(P>0.05)。结论祛湿清热针刺疗法能够有效降低急性湿疹患者AhR、IFN-γ、EOS、IL-17水平,降低炎症反应,疗效明显。展开更多
目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例...目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例。对照组剩42例(脱落5例)进行西医常规治疗。治疗组剩42例(脱落4例)在对照组基础上,进行养肺祛浊汤联合升清补气法针刺治疗。比较两组治疗14天的中医疗效。使用急性生理学和慢性健康状况量表(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评估患者的病情严重程度。运用改良英国呼吸困难指数量表(modified British medical research cuncil,mMRC)评估患者呼吸困难程度。使用慢阻肺评估量表(COPD assessment test,CAT)评估患者的生活质量。检测两组患者血清中动脉血氧分压(partial pressure of oxygen,PaO 2)、氧合指数(oxygenation index,OI)、浅快呼吸指数(rapid shallow breathing index,RSBI)、高迁移率族蛋白B1(high mobility group box b1,HMGB1)、超敏C反应蛋白(hypersensitivity creactive protein,hs-CRP)、中性粒细胞/淋巴细胞比值(neutrophit-to-lymphocyte ratio,NLR)的水平。比较两组肺功能的变化。结果治疗14天,治疗组的中医疗效比对照组高(95.24%vs 78.57%,P<0.05)。治疗后,两组的APACHEⅡ、mMRC、CAT均比治疗前低(P<0.05);治疗组治疗后的APACHEⅡ、mMRC、CAT均比对照组低(P<0.05)。治疗后,两组的PaO 2、OI比治疗前高,RSBI比治疗前低(P<0.05);治疗组治疗后的PaO 2、OI比对照组高,RSBI比对照组低(P<0.05)。两组治疗后的HMGB1、hs-CRP、NLR比治疗前低(P<0.05);治疗组治疗后的HMGB1、hs-CRP、NLR比对照组低(P<0.05)。治疗后,两组的第一秒呼出气体量/用力肺活量(forced expiratory volume in one second/forced vital capacity,FEV1/FVC)和最大呼气流量(peak expiratory flow,PEF)比治疗前高(P<0.05);治疗组治疗后的FEV1/FVC、PEF比对照组大(P<0.05)。结论养肺祛浊汤联合升清补气法针刺可提高AECOPD合并呼吸衰竭的中医疗效,减轻病情严重程度和呼吸困难程度,改善患者生活质量和血气指标,显著减轻炎症反应,提高肺功能。展开更多
In this study, the therapeutic effect of acupuncture and its effect on serum tumor necrosis factor apha (TNF-α) level was observed in 25 cases of allergic bronchial asthma patients. Acupoints used were Dazhui (GV 14)...In this study, the therapeutic effect of acupuncture and its effect on serum tumor necrosis factor apha (TNF-α) level was observed in 25 cases of allergic bronchial asthma patients. Acupoints used were Dazhui (GV 14), Feishu (BL 13), Dingchuan (EX-B 1), Pishu (BL 20), Tanzhong (CV 17), Shenshu (BL 23) and Fengchi (GB 20), supplemented with other acupoints according to syndrome differentiation. After 15 sessions of treatment, results showed that the total effective rate was 96% . Before treatment, serum TNF-oc activity was significantly higher than that of healthy subjects (25 cases, P<0.01). After treatment, TNF-α level reduced considerably in comparison with that of pre-treatment (P < 0. 05). These findings indicate that acupuncture can significantly improve allergic asthma patients' clinical symptoms and lower serum TNF-α activity.展开更多
The aim of this study was to develop a synthetic medium for the in vitro culture of bovine embryos, using various growth factors and cytokines （GF-CYK）： insulin-like growth factorl （IGF-Ⅰ）, insulin-like growth f...The aim of this study was to develop a synthetic medium for the in vitro culture of bovine embryos, using various growth factors and cytokines （GF-CYK）： insulin-like growth factorl （IGF-Ⅰ）, insulin-like growth factorⅡ （IGF-Ⅱ）, basic fibroblast growth factor （bFGF）, leukemia inhibitory factor （LIF）, granulocyte-macrophage colony stimulating factor （GM-CSF） and transforming growth factor beta Ⅰ （TGF-β1） ＋ hyaluronan （HA） ＋ recombinant albumin （RA）. The embryos were cultured in synthetic oviduct fluid （SOF） supplemented with： treatment 1 （T1）： bovine serum albumin （BSA） ＋ insulin, transferrin and selenium （ITS） （control）; or treatment 2 （T2）： GF-CYK ＋ HA ＋ RA. The blastocyst rates were not significantly different between TI and T2, at seven days post fertilization （dpf） （28.9% ± 2.4% and 31.8% ±2.2%）, and at 8 dpf （36.5% ±2.4% and 39.1% ±1.9%）, respectively （P 〉 0.05）. The total cell number （TCN） was significantly higher with T2 than that with T1 at 7 dpf（164.9 ±5.3 and 149.7 ±4.0） and 8 dpf （182.7 ±6.4 and 165.0 ±5.5） （P 〈 0.05）. The blastocyst diameter obtained with T2 was significantly greater （P 〈 0.05） than with T1 at 7 dpf （173.3 μm ±4.9 μm and 157.2μm ±4.1 μm, respectively）, however, no significant differences were observed at 8 dpf （190.3 μm 5.2 μm and 179.7 μm ± 5.3 μm, respectively）. In conclusion, the synthetic medium （T2） shows a comparable development rate to the control medium and improves the blastocyst diameter and the TCN.展开更多
Objective To detect the serum granulocyte colony-stimulating factor (G-CSF) levels betweenthe patients with frequently repeated infection ( repeaters) and others (non-repeaters) in different phase of infection.Methods...Objective To detect the serum granulocyte colony-stimulating factor (G-CSF) levels betweenthe patients with frequently repeated infection ( repeaters) and others (non-repeaters) in different phase of infection.Methods An enzyme-linked immunosorbent assay (ELISA) method was used to detect serum G-CSF levels in 50cases (32 non-repeaters and 18 repeaters) with acute phase of infection. Serum G-CSF levels were detected inrecovery phase in 10 cases. Results Serum G-CSF levels were significantly higher (1429. 97 ±506. 43ng/L) in32 non-repeaters with acute infection. There was a positive correlation between white blood cell count ( WBC) andserum G-CSF level (r =0. 396, P <0. 05). There was also a positive correlation between absolute neutrophil count(ANC) and serum G-CSF level (r =0. 346,P <0. 05). Serum G-CSF levels were higher (98. 62 ±56. 40ng/L) in18 repeaters with acute infection. It was showed that serum G-CSF levels were significantly higher in non-repeatersthan in repeaters with acute phase of infection (P <0. 001). In the meanwhile, the body temperature was signifi-cantly higher in non-repeaters than in repeaters with acute infection (37. 95 ±0. 14 vs 36. 91 ±0. 13 ,P<0. 001). There were no significant differences in age, WBC, ANC, type of bacterial, liver function and renal func-tion (P >0. 05). Serum G-CSF levels in recovery phase of the two groups were below the sensitivity of the assay( <60 ng/L). Conclusion It is suggested that application of recombinant G-CSF may be useful for the patientswith repeated infection.展开更多
Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation g...Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation group （30 cases） was treated with speech therapy and acupuncture at major acupoints Lianquan （廉泉 CV 23）, Jinjin （金津 EX-HN 12）, Yuye （玉夜 EX-HN 13）, Fengchi（风池 GB 20）, Yifeng （翳风 TE 17） and Wangu（完骨 GB 12）, and the control group （31 cases） was treated with speech therapy only. The changes of speech and acoustical indices were evaluated after 9 weeks treatment. Results The word articulation and the correct rate of writings in the two groups were significantly increased after treatment （both P〈0.01）. The total effective rate of 96.7%（29/30） in the observation group was superior to that of 67.7%（21/31） in the control group （P〈0.01）. The maximum phonation time （MPT） tested by a phonolaryngeal aeromechanical analyzer was significantly prolonged in both the observation group （12 cases） and the control group （11 cases） （both P〈0.01）, the improvement in the observation group being more obvious （P〈0.01）. Conclusion Acupuncture combined with speech therapy can improve the speech and acoustic level in the patient of dysarthria.展开更多
Objective： To explore a method of analyzing the components of anti-asthma activity in serum derived from rats treated with acupuncture. Methods： SDS-PAGE was used to analyze the diversity of the components of serum ...Objective： To explore a method of analyzing the components of anti-asthma activity in serum derived from rats treated with acupuncture. Methods： SDS-PAGE was used to analyze the diversity of the components of serum derived from rats treated with or without acupuncture treatment. Results： SDS-PAGE images displayed that there are one deeply dyed band, whose molecular weight is 62.1 kDa, in the component I from asthma acupuncture group and ADX-asthma acupuncture group, two deeply dyed bands, whose molecular weight are 36. lkDa and 12.3 kDa, respectively, in the component Ⅲ of ADX-asthma acupuncture group, and one dyed band, whose molecular weight is 34.6 kDa, in the segment Ⅲ of ADX-asthma acupuncture group. Conclusion： Acupuncture treatment could produce different components in the serum of rats, and may have bidirectional regulation on protein components in serum.展开更多
Objective： To investigate the effect of acupuncture on serum superoxide dismutase（SOD） and malondialdehyde（MDA） of rats in menopause. Methods： Female rats in menopause were randomly allocated into acupuncture, d...Objective： To investigate the effect of acupuncture on serum superoxide dismutase（SOD） and malondialdehyde（MDA） of rats in menopause. Methods： Female rats in menopause were randomly allocated into acupuncture, drugs and control groups, which were treated with acupuncture, Gengnian＇an Tablet, and nothing, respectively. In addition, some young female rats were used as control. After 17-day treatments, serum SOD and MDA were measured with biochemical methods. Results： Compared with the young rats, rats in menopause had lower contents of serum SOD（P〈0.01）, and higher contents of MDA（P〈0.01）. After acupuncture treatment, the contents of serum SOD increased（P〈0.05）, and MDA decreased（P〈0.05）. Conclusion： Acupuncture could increase the serum SOD contents and decrease the serum MDA contents of rats in menopause.展开更多
文摘目的探讨祛湿清热针刺疗法对急性湿疹患者AhR、IFN-γ、EOS、IL-17水平的影响。方法选取2021年11月—2023年7月期间于马鞍山中医院收治的78例急性湿疹患者,采用随机数字表法分为对照组和治疗组,每组各39例。对照组给予常规治疗,治疗组给予祛湿清热针刺疗法治疗。治疗2周后,观察比较两组患者临床疗效、不良反应情况,治疗前后中医证候评分、湿疹面积及严重度指数(Eczema area and severity index,EASI)评分、视觉模拟评分法(Visual pain scale,VAS)评分、实验室检查指标[嗜酸性粒细胞(Eosinophil,EOS)、白细胞介素-17(Interleukin-17,IL-17)、干扰素-γ(Interferon,IFN-γ)、芳香烃受体(Aromatic hydrocarbon receptor,AhR)]、皮肤生理功能指标。结果治疗后治疗组临床总有效率97.44%(38/39)明显高于对照组82.05%(32/39),差异有统计学意义(P<0.05)。治疗后两组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组患者发病急、病程短、渗出明显、皮损潮红、伴红疹、灼热瘙痒、自觉发热、口渴欲饮、心烦评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者EASI、VAS评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组EASI、VAS评分均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者AhR、IL-17、IFN-γ、EOS水平均较治疗前降低,差异有统计学意义(P<0.05);且治疗组AhR、IL-17、IFN-γ、EOS水平均较对照组明显降低,差异有统计学意义(P<0.05)。治疗后两组患者皮肤生理功能指标较治疗前升高,差异有统计学意义(P<0.05);且治疗组皮肤生理功能指标较对照组明显升高,差异有统计学意义(P<0.05)。治疗期间,治疗组不良反应发生率7.69%(3/39)与对照组17.95%(7/39)比较,差异无统计学意义(P>0.05)。结论祛湿清热针刺疗法能够有效降低急性湿疹患者AhR、IFN-γ、EOS、IL-17水平,降低炎症反应,疗效明显。
文摘目的探讨养肺祛浊汤联合升清补气法针刺治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭的临床疗效。方法将93例AECOPD合并呼吸衰竭患者分为治疗组47例和对照组46例。对照组剩42例(脱落5例)进行西医常规治疗。治疗组剩42例(脱落4例)在对照组基础上,进行养肺祛浊汤联合升清补气法针刺治疗。比较两组治疗14天的中医疗效。使用急性生理学和慢性健康状况量表(acute physiology and chronic health evaluationⅡ,APACHEⅡ)评估患者的病情严重程度。运用改良英国呼吸困难指数量表(modified British medical research cuncil,mMRC)评估患者呼吸困难程度。使用慢阻肺评估量表(COPD assessment test,CAT)评估患者的生活质量。检测两组患者血清中动脉血氧分压(partial pressure of oxygen,PaO 2)、氧合指数(oxygenation index,OI)、浅快呼吸指数(rapid shallow breathing index,RSBI)、高迁移率族蛋白B1(high mobility group box b1,HMGB1)、超敏C反应蛋白(hypersensitivity creactive protein,hs-CRP)、中性粒细胞/淋巴细胞比值(neutrophit-to-lymphocyte ratio,NLR)的水平。比较两组肺功能的变化。结果治疗14天,治疗组的中医疗效比对照组高(95.24%vs 78.57%,P<0.05)。治疗后,两组的APACHEⅡ、mMRC、CAT均比治疗前低(P<0.05);治疗组治疗后的APACHEⅡ、mMRC、CAT均比对照组低(P<0.05)。治疗后,两组的PaO 2、OI比治疗前高,RSBI比治疗前低(P<0.05);治疗组治疗后的PaO 2、OI比对照组高,RSBI比对照组低(P<0.05)。两组治疗后的HMGB1、hs-CRP、NLR比治疗前低(P<0.05);治疗组治疗后的HMGB1、hs-CRP、NLR比对照组低(P<0.05)。治疗后,两组的第一秒呼出气体量/用力肺活量(forced expiratory volume in one second/forced vital capacity,FEV1/FVC)和最大呼气流量(peak expiratory flow,PEF)比治疗前高(P<0.05);治疗组治疗后的FEV1/FVC、PEF比对照组大(P<0.05)。结论养肺祛浊汤联合升清补气法针刺可提高AECOPD合并呼吸衰竭的中医疗效,减轻病情严重程度和呼吸困难程度,改善患者生活质量和血气指标,显著减轻炎症反应,提高肺功能。
文摘In this study, the therapeutic effect of acupuncture and its effect on serum tumor necrosis factor apha (TNF-α) level was observed in 25 cases of allergic bronchial asthma patients. Acupoints used were Dazhui (GV 14), Feishu (BL 13), Dingchuan (EX-B 1), Pishu (BL 20), Tanzhong (CV 17), Shenshu (BL 23) and Fengchi (GB 20), supplemented with other acupoints according to syndrome differentiation. After 15 sessions of treatment, results showed that the total effective rate was 96% . Before treatment, serum TNF-oc activity was significantly higher than that of healthy subjects (25 cases, P<0.01). After treatment, TNF-α level reduced considerably in comparison with that of pre-treatment (P < 0. 05). These findings indicate that acupuncture can significantly improve allergic asthma patients' clinical symptoms and lower serum TNF-α activity.
文摘The aim of this study was to develop a synthetic medium for the in vitro culture of bovine embryos, using various growth factors and cytokines （GF-CYK）： insulin-like growth factorl （IGF-Ⅰ）, insulin-like growth factorⅡ （IGF-Ⅱ）, basic fibroblast growth factor （bFGF）, leukemia inhibitory factor （LIF）, granulocyte-macrophage colony stimulating factor （GM-CSF） and transforming growth factor beta Ⅰ （TGF-β1） ＋ hyaluronan （HA） ＋ recombinant albumin （RA）. The embryos were cultured in synthetic oviduct fluid （SOF） supplemented with： treatment 1 （T1）： bovine serum albumin （BSA） ＋ insulin, transferrin and selenium （ITS） （control）; or treatment 2 （T2）： GF-CYK ＋ HA ＋ RA. The blastocyst rates were not significantly different between TI and T2, at seven days post fertilization （dpf） （28.9% ± 2.4% and 31.8% ±2.2%）, and at 8 dpf （36.5% ±2.4% and 39.1% ±1.9%）, respectively （P 〉 0.05）. The total cell number （TCN） was significantly higher with T2 than that with T1 at 7 dpf（164.9 ±5.3 and 149.7 ±4.0） and 8 dpf （182.7 ±6.4 and 165.0 ±5.5） （P 〈 0.05）. The blastocyst diameter obtained with T2 was significantly greater （P 〈 0.05） than with T1 at 7 dpf （173.3 μm ±4.9 μm and 157.2μm ±4.1 μm, respectively）, however, no significant differences were observed at 8 dpf （190.3 μm 5.2 μm and 179.7 μm ± 5.3 μm, respectively）. In conclusion, the synthetic medium （T2） shows a comparable development rate to the control medium and improves the blastocyst diameter and the TCN.
文摘Objective To detect the serum granulocyte colony-stimulating factor (G-CSF) levels betweenthe patients with frequently repeated infection ( repeaters) and others (non-repeaters) in different phase of infection.Methods An enzyme-linked immunosorbent assay (ELISA) method was used to detect serum G-CSF levels in 50cases (32 non-repeaters and 18 repeaters) with acute phase of infection. Serum G-CSF levels were detected inrecovery phase in 10 cases. Results Serum G-CSF levels were significantly higher (1429. 97 ±506. 43ng/L) in32 non-repeaters with acute infection. There was a positive correlation between white blood cell count ( WBC) andserum G-CSF level (r =0. 396, P <0. 05). There was also a positive correlation between absolute neutrophil count(ANC) and serum G-CSF level (r =0. 346,P <0. 05). Serum G-CSF levels were higher (98. 62 ±56. 40ng/L) in18 repeaters with acute infection. It was showed that serum G-CSF levels were significantly higher in non-repeatersthan in repeaters with acute phase of infection (P <0. 001). In the meanwhile, the body temperature was signifi-cantly higher in non-repeaters than in repeaters with acute infection (37. 95 ±0. 14 vs 36. 91 ±0. 13 ,P<0. 001). There were no significant differences in age, WBC, ANC, type of bacterial, liver function and renal func-tion (P >0. 05). Serum G-CSF levels in recovery phase of the two groups were below the sensitivity of the assay( <60 ng/L). Conclusion It is suggested that application of recombinant G-CSF may be useful for the patientswith repeated infection.
基金Supported by Scientific Research Project of China Rehabilitation Research Center:2006-23
文摘Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation group （30 cases） was treated with speech therapy and acupuncture at major acupoints Lianquan （廉泉 CV 23）, Jinjin （金津 EX-HN 12）, Yuye （玉夜 EX-HN 13）, Fengchi（风池 GB 20）, Yifeng （翳风 TE 17） and Wangu（完骨 GB 12）, and the control group （31 cases） was treated with speech therapy only. The changes of speech and acoustical indices were evaluated after 9 weeks treatment. Results The word articulation and the correct rate of writings in the two groups were significantly increased after treatment （both P〈0.01）. The total effective rate of 96.7%（29/30） in the observation group was superior to that of 67.7%（21/31） in the control group （P〈0.01）. The maximum phonation time （MPT） tested by a phonolaryngeal aeromechanical analyzer was significantly prolonged in both the observation group （12 cases） and the control group （11 cases） （both P〈0.01）, the improvement in the observation group being more obvious （P〈0.01）. Conclusion Acupuncture combined with speech therapy can improve the speech and acoustic level in the patient of dysarthria.
基金National Natural Science Funds (90409014,30171177, 30701123)National Basic Research Program of China (973 Program, 2005CB523306-5)+2 种基金Shanghai Committee of Science and Technique (02DZ19150-5)The Key laboratory of acupuncture-immune effects of State Administration of Traditional Chinese MedicineShanghai Leading Academic Discipline Project (S30304)
文摘Objective： To explore a method of analyzing the components of anti-asthma activity in serum derived from rats treated with acupuncture. Methods： SDS-PAGE was used to analyze the diversity of the components of serum derived from rats treated with or without acupuncture treatment. Results： SDS-PAGE images displayed that there are one deeply dyed band, whose molecular weight is 62.1 kDa, in the component I from asthma acupuncture group and ADX-asthma acupuncture group, two deeply dyed bands, whose molecular weight are 36. lkDa and 12.3 kDa, respectively, in the component Ⅲ of ADX-asthma acupuncture group, and one dyed band, whose molecular weight is 34.6 kDa, in the segment Ⅲ of ADX-asthma acupuncture group. Conclusion： Acupuncture treatment could produce different components in the serum of rats, and may have bidirectional regulation on protein components in serum.
基金Education committee of Shanghai(03CK21)Shanghai Leading Academic Discipline Project(T0302)
文摘Objective： To investigate the effect of acupuncture on serum superoxide dismutase（SOD） and malondialdehyde（MDA） of rats in menopause. Methods： Female rats in menopause were randomly allocated into acupuncture, drugs and control groups, which were treated with acupuncture, Gengnian＇an Tablet, and nothing, respectively. In addition, some young female rats were used as control. After 17-day treatments, serum SOD and MDA were measured with biochemical methods. Results： Compared with the young rats, rats in menopause had lower contents of serum SOD（P〈0.01）, and higher contents of MDA（P〈0.01）. After acupuncture treatment, the contents of serum SOD increased（P〈0.05）, and MDA decreased（P〈0.05）. Conclusion： Acupuncture could increase the serum SOD contents and decrease the serum MDA contents of rats in menopause.
