AIM： TO explore the pathogenesis of the rectovestibular disruption （RVD） defect and to recommend a successful repair, and prevention of it. METHODS： Clinical records of 15 girls, age ranged from 3 to 15 （median, ...AIM： TO explore the pathogenesis of the rectovestibular disruption （RVD） defect and to recommend a successful repair, and prevention of it. METHODS： Clinical records of 15 girls, age ranged from 3 to 15 （median, 7.5） years, with acquired rectovestibular fistula （RVF） mistreated before were retrospectively reviewed. All of them presented an abnormal appearance of perineum and were suffering from some degree of fecal incontinence, and those were graded Ⅲ to IV by Li Zheng＇s Score. Repair of anal sphincters and reconstruction of perineum body and skin by anterior perineal rectoanoplasty were performed in all cases. RESULTS： Operation in all cases was successful. The perin.eum looked practically normal and fecal continence score rose up to VI by Li Zheng＇s Score. CONCLUSION： The conventional treatment for anal fistula, lay-open or string-treatment, should be considered as malpractice of RVF, and certainly leads to the RVD defect, and the anterior perineal rectoanoplasty could cure it satisfactorily.展开更多
Objective: To evaluate the plasma concentration of thrombus precursor protein (TPP) in patients after mechanical heart valve replacement, and to explore whether it can be used as a marker for monitoring anticoagulatio...Objective: To evaluate the plasma concentration of thrombus precursor protein (TPP) in patients after mechanical heart valve replacement, and to explore whether it can be used as a marker for monitoring anticoagulation. Methods: Totally 60 patients who took warfarin after mitral valve replacement and 20 control patients with non-valvular heart diseases were subjected in this study. Their plasma TPP concentration and international normalized ratio (INR) were determined, and compared not only between the anticoagulant patients and the control patients, but also between the patients with atrial fibrillaiton (AF, n=37) and the patients with sinus rhythm (SR, n=23) after mechanical valve replacement. The relationship between plasma TPP concentration and INR in the 60 anticoagulant patients was analyzed with linear regression. Results: It was found that the anticoagulant therapy effectively decreased plasma TPP concentration and elevated INR. In the anticoagulant group, the patients with AF had higher plasma TPP concentration than the others with sinus rhythm (P<0.05), although there was no significant difference in INR level between these 2 groups of patients (P>0.05). No significant correlation was found between plasma TPP concentration and INR in the anticoagulant patients (P>0.05). INR did not accord with plasma TPP concentration in several patients. Conclusion: INR can’t reflect the coagulation status and guide the anticoagulation correctly sometimes; TPP may be a valuable assistant marker for monitoring anticoagulation in patients with mechanical heart valve prothesis; Patients with AF may require higher density of anticoagulation and TPP is strongly suggested to be monitored in these patients.展开更多
目的探讨利托君与硫酸镁用于前置胎盘期待疗法的效果。方法 60例前置胎盘产妇随机分为利托君组、硫酸镁组、对照组,观察阴道流血停止时间、药物显效时间、延长孕期天数、1 min Apgar评分、新生儿体重等。结果阴道流血时间、药物显效时间...目的探讨利托君与硫酸镁用于前置胎盘期待疗法的效果。方法 60例前置胎盘产妇随机分为利托君组、硫酸镁组、对照组,观察阴道流血停止时间、药物显效时间、延长孕期天数、1 min Apgar评分、新生儿体重等。结果阴道流血时间、药物显效时间,利托君组比硫酸镁组减少显著,P<0.05;延长孕期天数,利托君组比硫酸镁组延长显著,P<0.05;产后1 min Apgar评分、新生儿体重,利托君组与硫酸镁组比较有显着意义,P<0.05。结论利托君治疗前置胎盘效果好于硫酸镁。展开更多
文摘AIM： TO explore the pathogenesis of the rectovestibular disruption （RVD） defect and to recommend a successful repair, and prevention of it. METHODS： Clinical records of 15 girls, age ranged from 3 to 15 （median, 7.5） years, with acquired rectovestibular fistula （RVF） mistreated before were retrospectively reviewed. All of them presented an abnormal appearance of perineum and were suffering from some degree of fecal incontinence, and those were graded Ⅲ to IV by Li Zheng＇s Score. Repair of anal sphincters and reconstruction of perineum body and skin by anterior perineal rectoanoplasty were performed in all cases. RESULTS： Operation in all cases was successful. The perin.eum looked practically normal and fecal continence score rose up to VI by Li Zheng＇s Score. CONCLUSION： The conventional treatment for anal fistula, lay-open or string-treatment, should be considered as malpractice of RVF, and certainly leads to the RVD defect, and the anterior perineal rectoanoplasty could cure it satisfactorily.
文摘Objective: To evaluate the plasma concentration of thrombus precursor protein (TPP) in patients after mechanical heart valve replacement, and to explore whether it can be used as a marker for monitoring anticoagulation. Methods: Totally 60 patients who took warfarin after mitral valve replacement and 20 control patients with non-valvular heart diseases were subjected in this study. Their plasma TPP concentration and international normalized ratio (INR) were determined, and compared not only between the anticoagulant patients and the control patients, but also between the patients with atrial fibrillaiton (AF, n=37) and the patients with sinus rhythm (SR, n=23) after mechanical valve replacement. The relationship between plasma TPP concentration and INR in the 60 anticoagulant patients was analyzed with linear regression. Results: It was found that the anticoagulant therapy effectively decreased plasma TPP concentration and elevated INR. In the anticoagulant group, the patients with AF had higher plasma TPP concentration than the others with sinus rhythm (P<0.05), although there was no significant difference in INR level between these 2 groups of patients (P>0.05). No significant correlation was found between plasma TPP concentration and INR in the anticoagulant patients (P>0.05). INR did not accord with plasma TPP concentration in several patients. Conclusion: INR can’t reflect the coagulation status and guide the anticoagulation correctly sometimes; TPP may be a valuable assistant marker for monitoring anticoagulation in patients with mechanical heart valve prothesis; Patients with AF may require higher density of anticoagulation and TPP is strongly suggested to be monitored in these patients.
文摘目的探讨利托君与硫酸镁用于前置胎盘期待疗法的效果。方法 60例前置胎盘产妇随机分为利托君组、硫酸镁组、对照组,观察阴道流血停止时间、药物显效时间、延长孕期天数、1 min Apgar评分、新生儿体重等。结果阴道流血时间、药物显效时间,利托君组比硫酸镁组减少显著,P<0.05;延长孕期天数,利托君组比硫酸镁组延长显著,P<0.05;产后1 min Apgar评分、新生儿体重,利托君组与硫酸镁组比较有显着意义,P<0.05。结论利托君治疗前置胎盘效果好于硫酸镁。
