Background: Nevi are potential precursors of malignant melanoma and are important risk factors for the development of the disease. Childhood may be a critical time for the formation and evolution of nevi. Objectives: ...Background: Nevi are potential precursors of malignant melanoma and are important risk factors for the development of the disease. Childhood may be a critical time for the formation and evolution of nevi. Objectives: To document the devel opment of new nevi and to document the clinical and dermoscopic changes in index nevi in school children during a 1-year follow-up. Methods: Digital photograp hs and dermoscopic images of the back of subjects were compared at baseline and 1-year follow-up to assess changes in nevi counts and in clinical and dermosco pic features of index nevi. Results: Overall participation rate was 81%(42/52). 56.4%of study participants were found to have an increased number of nevi at 1 -year follow-up. All nevi were small and clinically insignificant. Fifty perce nt of study participants were found to have dermoscopic changes in their index n evi at 1-year follow-up. Eighty-five percent of these changes were classified as subtle and 15.0%as obvious. Conclusions: A significant portion of students developed new nevi over the course of 1 year. Most index nevi remained stable in pattern and structure. Benign dermoscopic changes occurred in 50.0%of index ne vi. However, none of the dermoscopically changed nevi revealed any major changes and the overall nevus pattern remained unchanged. The relevance of these change s is uncertain and further follow-up may elucidate their significance.展开更多
文摘Background: Nevi are potential precursors of malignant melanoma and are important risk factors for the development of the disease. Childhood may be a critical time for the formation and evolution of nevi. Objectives: To document the devel opment of new nevi and to document the clinical and dermoscopic changes in index nevi in school children during a 1-year follow-up. Methods: Digital photograp hs and dermoscopic images of the back of subjects were compared at baseline and 1-year follow-up to assess changes in nevi counts and in clinical and dermosco pic features of index nevi. Results: Overall participation rate was 81%(42/52). 56.4%of study participants were found to have an increased number of nevi at 1 -year follow-up. All nevi were small and clinically insignificant. Fifty perce nt of study participants were found to have dermoscopic changes in their index n evi at 1-year follow-up. Eighty-five percent of these changes were classified as subtle and 15.0%as obvious. Conclusions: A significant portion of students developed new nevi over the course of 1 year. Most index nevi remained stable in pattern and structure. Benign dermoscopic changes occurred in 50.0%of index ne vi. However, none of the dermoscopically changed nevi revealed any major changes and the overall nevus pattern remained unchanged. The relevance of these change s is uncertain and further follow-up may elucidate their significance.
