We theoretically analyze the reflection spectra of the fiber Bragg gratings in the quadratic strain field,and resolve the numerical value with transfer matrix method.When the value of pressure is changed,we can obtain...We theoretically analyze the reflection spectra of the fiber Bragg gratings in the quadratic strain field,and resolve the numerical value with transfer matrix method.When the value of pressure is changed,we can obtain diverse reflection spectra of the fiber Bragg gratings,which is in good accordance with the experimental results.展开更多
This paper deals mainly with the dynamic response of a rigid disc bonded to the surface of a layered poroelastic half-space. The disc is subjected to time-harmonic torsional moment loadings. The half space under consi...This paper deals mainly with the dynamic response of a rigid disc bonded to the surface of a layered poroelastic half-space. The disc is subjected to time-harmonic torsional moment loadings. The half space under consideration consists of a number of layers with different thickness and material properties. Hankel transform techniques and transferring matrix method are used to solve the governing equations. The continuity of the displacement and stress fields between different layers enabled derivation of closed-form solutions in the transform domain. On the assumption that the contact between the disc and the half space is perfectly bonded, this dynamic mixed boundary-value problem can be reduced to dual integral equations, which are further reduced to Fredholm integral equations of the second kind and solved by numerical procedures. Selected numerical results for the dynamic impedance and displacement amplitude of the disc resting on different saturated models are presented to show the influence of the material and geometrical properties of both the saturated soil-foundation system and the nature of the load acting on it. The conclusions obtained can serve as guidelines for practical engineering.展开更多
Objective: The membrane-linking protein Ezrin is highly expressed in several types of human cancers. The cor- relations between its immunoreactivity and histopathological data as well as patient outcome have previousl...Objective: The membrane-linking protein Ezrin is highly expressed in several types of human cancers. The cor- relations between its immunoreactivity and histopathological data as well as patient outcome have previously been shown. However, the role played by Ezrin in the carcinogenesis, progression and metastasis of primary sporadic colorectal carcinoma (SCRC) is still under investigation. This study assessed Ezrin protein expression in a series of clinical specimens. Methods: Immunohistochemical analysis was used to characterize patterns of Ezrin expression in 132 cases of SCRC, including 74 metastatic cases and 58 non-metastatic cases and 43 adjacent normal colorectal mucosa. Results: (1) The expression rate of Ezrin in SCRC (79.5%) was significantly higher than in adjacent normal colorectal mucosa (11.6%) (P < 0.001); (2) The total expression rate of Ezrin was 86.5% and 70.7% in metastatic group and non-metastatic group, respectively (P = 0.026); the membrane expression rate of Ezrin was 31.1% and 6.9% in the two groups, respectively (P < 0.01); (3) There was no relation- ship between the expression of Ezrin with age, gender, tumor size, location, degree of differentiation and invasive depth; (4) In the cases with followed-up data, univariate analysis demonstrated that Ezrin expression and its membrane translocation was correlated with worse patient’s disease-free survival (DFS) (Puni < 0.05). Conclusion: Ezrin was expressed in the majority of SCRC and associated with adverse prognostic factors. The increase expression and the switch of Ezrin localization from the cytoplasm to the membrane were closely correlated with metastasis in SCRC. It might be served as an important parameter for determining tumor biological behavior.展开更多
A flexible fibre biofilm reactor was developed for treatment of organic wastewaters.The hydrodynamic characteristics and mass transfer coefficients of oxygen were studied and compared with those of the conventional ac...A flexible fibre biofilm reactor was developed for treatment of organic wastewaters.The hydrodynamic characteristics and mass transfer coefficients of oxygen were studied and compared with those of the conventional activated sludge processes.Tracer experiments were performed to obtain the residence time distributions of the reactors.The results indicated that both reactors could be treated as mixed flow reactors.The effects of flow rates of water and air on the overall mass transfer coefficient of oxygen were investigated,and the correlations between the mass transfer coefficient and the ratio of flow rates were obtained.Compared to the conventional activated sludge reactor,the mass transfer coefficients in the flexible fibre reactor were similar to but slightly lower,and less sensitive to the variation in the ratio of flow rates.It indicated that the fibre packing in the reactor hindered the oxygen transfer to some extent.展开更多
The efficiency,robustness and reliability of recent numerical methods for finding solutions to flow problems have given rise to the implementation of computational fluid dynamics(CFD) as a broadly used analysis method...The efficiency,robustness and reliability of recent numerical methods for finding solutions to flow problems have given rise to the implementation of computational fluid dynamics(CFD) as a broadly used analysis method for engineering problems like membrane separation system.The CFD modeling in this study observes steady and unsteady(transient) heat flux and temperature profiles in a polymeric(cellulose acetate) membrane.This study is novel due to the implementation of user defined scalar(UDS) diffusion equation by using user-defined functions(UDFs) infinite volume method(FVM).Some details of the FVM used by the solver are carefully discussed when implementing terms in the governing equation and boundary conditions(BC).The contours of temperature due to high-temperature gradient are reported for steady and unsteady problems.展开更多
基金Supported by the National Natural Science Foundation of China(60577018) Science and Technology Innovation Foundation of Nankai University and the Opening Project (2005-06) of KeyLaboratory of Optoelectronic Information Science and Technolo-gy ,Ministry of Education,China .
文摘We theoretically analyze the reflection spectra of the fiber Bragg gratings in the quadratic strain field,and resolve the numerical value with transfer matrix method.When the value of pressure is changed,we can obtain diverse reflection spectra of the fiber Bragg gratings,which is in good accordance with the experimental results.
基金Project (No. 50079027) supported by the National Natural ScienceFoundation of China
文摘This paper deals mainly with the dynamic response of a rigid disc bonded to the surface of a layered poroelastic half-space. The disc is subjected to time-harmonic torsional moment loadings. The half space under consideration consists of a number of layers with different thickness and material properties. Hankel transform techniques and transferring matrix method are used to solve the governing equations. The continuity of the displacement and stress fields between different layers enabled derivation of closed-form solutions in the transform domain. On the assumption that the contact between the disc and the half space is perfectly bonded, this dynamic mixed boundary-value problem can be reduced to dual integral equations, which are further reduced to Fredholm integral equations of the second kind and solved by numerical procedures. Selected numerical results for the dynamic impedance and displacement amplitude of the disc resting on different saturated models are presented to show the influence of the material and geometrical properties of both the saturated soil-foundation system and the nature of the load acting on it. The conclusions obtained can serve as guidelines for practical engineering.
基金the Sciences and Technique Development Foundation of Shanghai (No. 024119010).
文摘Objective: The membrane-linking protein Ezrin is highly expressed in several types of human cancers. The cor- relations between its immunoreactivity and histopathological data as well as patient outcome have previously been shown. However, the role played by Ezrin in the carcinogenesis, progression and metastasis of primary sporadic colorectal carcinoma (SCRC) is still under investigation. This study assessed Ezrin protein expression in a series of clinical specimens. Methods: Immunohistochemical analysis was used to characterize patterns of Ezrin expression in 132 cases of SCRC, including 74 metastatic cases and 58 non-metastatic cases and 43 adjacent normal colorectal mucosa. Results: (1) The expression rate of Ezrin in SCRC (79.5%) was significantly higher than in adjacent normal colorectal mucosa (11.6%) (P < 0.001); (2) The total expression rate of Ezrin was 86.5% and 70.7% in metastatic group and non-metastatic group, respectively (P = 0.026); the membrane expression rate of Ezrin was 31.1% and 6.9% in the two groups, respectively (P < 0.01); (3) There was no relation- ship between the expression of Ezrin with age, gender, tumor size, location, degree of differentiation and invasive depth; (4) In the cases with followed-up data, univariate analysis demonstrated that Ezrin expression and its membrane translocation was correlated with worse patient’s disease-free survival (DFS) (Puni < 0.05). Conclusion: Ezrin was expressed in the majority of SCRC and associated with adverse prognostic factors. The increase expression and the switch of Ezrin localization from the cytoplasm to the membrane were closely correlated with metastasis in SCRC. It might be served as an important parameter for determining tumor biological behavior.
文摘A flexible fibre biofilm reactor was developed for treatment of organic wastewaters.The hydrodynamic characteristics and mass transfer coefficients of oxygen were studied and compared with those of the conventional activated sludge processes.Tracer experiments were performed to obtain the residence time distributions of the reactors.The results indicated that both reactors could be treated as mixed flow reactors.The effects of flow rates of water and air on the overall mass transfer coefficient of oxygen were investigated,and the correlations between the mass transfer coefficient and the ratio of flow rates were obtained.Compared to the conventional activated sludge reactor,the mass transfer coefficients in the flexible fibre reactor were similar to but slightly lower,and less sensitive to the variation in the ratio of flow rates.It indicated that the fibre packing in the reactor hindered the oxygen transfer to some extent.
文摘The efficiency,robustness and reliability of recent numerical methods for finding solutions to flow problems have given rise to the implementation of computational fluid dynamics(CFD) as a broadly used analysis method for engineering problems like membrane separation system.The CFD modeling in this study observes steady and unsteady(transient) heat flux and temperature profiles in a polymeric(cellulose acetate) membrane.This study is novel due to the implementation of user defined scalar(UDS) diffusion equation by using user-defined functions(UDFs) infinite volume method(FVM).Some details of the FVM used by the solver are carefully discussed when implementing terms in the governing equation and boundary conditions(BC).The contours of temperature due to high-temperature gradient are reported for steady and unsteady problems.