在对胸部CT(Computed Tomography)序列图像进行慢性阻塞性等肺疾病诊断时,需要获取相关的肺功能指标来给医生提供参考依据。为此,开发了一个用于肺功能定量分析的计算机辅助系统。系统首先结合多种分割方法实现了三维肺实质的分割,然后...在对胸部CT(Computed Tomography)序列图像进行慢性阻塞性等肺疾病诊断时,需要获取相关的肺功能指标来给医生提供参考依据。为此,开发了一个用于肺功能定量分析的计算机辅助系统。系统首先结合多种分割方法实现了三维肺实质的分割,然后采用体绘制技术重建出肺部组织的三维模型,最后利用分割结果实现了对肺功能指标的定量分析。此外,针对医生个性化的需求,该系统还实现了局部肺实质VOI(Volume of Interest)的肺功能定量分析和肺实质任意指定感兴趣CT值范围内的肺功能定量分析。展开更多
为了更加便利、快捷地在基于CT的肺部疾病诊断中获取相关肺功能指标,以便于辅助医生进行诊断,本研究开发了基于肺部组织分割的肺功能定量分析系统。系统主要分为三个部分:肺部组织的分割,肺部组织的三维重建以及肺功能定量分析模块。在...为了更加便利、快捷地在基于CT的肺部疾病诊断中获取相关肺功能指标,以便于辅助医生进行诊断,本研究开发了基于肺部组织分割的肺功能定量分析系统。系统主要分为三个部分:肺部组织的分割,肺部组织的三维重建以及肺功能定量分析模块。在利用已有方法分割出肺实质、肺气管和肺血管的基础上,提出了自动修补由肺结节造成的肺实质孔洞以及肺边缘缺陷的方法,利用基于海森矩阵的圆点增强算法分割出疑似肺结节区域,结合手动选取种子点确定明显肺结节。实现了肺部多组织的三维重建,可计算整体、局部(volume of interest,VOI)区域以及感兴趣CT值范围内的肺功能指标从而进行肺功能定量分析,并可在二维和三维上定位显示测算对象,结合多方面辅助医生诊断。展开更多
Proteomics focuses on the systematic identification and quantification of entire proteomes and interpretation of proteins’biological functions.During the last decade,proteomics in China has grown much faster than oth...Proteomics focuses on the systematic identification and quantification of entire proteomes and interpretation of proteins’biological functions.During the last decade,proteomics in China has grown much faster than other research fields in life sciences.At the beginning of the second decade of the 21st century,the rapid development of high-resolution and high-speed mass spectrometry makes proteomics a powerful tool to study the mechanisms underlying physiological/pathological processes in organisms.This article provides a brief overview of proteomics technology development and representative scientific progress of the Human Liver Proteome Project in China over the past three years.展开更多
文摘在对胸部CT(Computed Tomography)序列图像进行慢性阻塞性等肺疾病诊断时,需要获取相关的肺功能指标来给医生提供参考依据。为此,开发了一个用于肺功能定量分析的计算机辅助系统。系统首先结合多种分割方法实现了三维肺实质的分割,然后采用体绘制技术重建出肺部组织的三维模型,最后利用分割结果实现了对肺功能指标的定量分析。此外,针对医生个性化的需求,该系统还实现了局部肺实质VOI(Volume of Interest)的肺功能定量分析和肺实质任意指定感兴趣CT值范围内的肺功能定量分析。
文摘为了更加便利、快捷地在基于CT的肺部疾病诊断中获取相关肺功能指标,以便于辅助医生进行诊断,本研究开发了基于肺部组织分割的肺功能定量分析系统。系统主要分为三个部分:肺部组织的分割,肺部组织的三维重建以及肺功能定量分析模块。在利用已有方法分割出肺实质、肺气管和肺血管的基础上,提出了自动修补由肺结节造成的肺实质孔洞以及肺边缘缺陷的方法,利用基于海森矩阵的圆点增强算法分割出疑似肺结节区域,结合手动选取种子点确定明显肺结节。实现了肺部多组织的三维重建,可计算整体、局部(volume of interest,VOI)区域以及感兴趣CT值范围内的肺功能指标从而进行肺功能定量分析,并可在二维和三维上定位显示测算对象,结合多方面辅助医生诊断。
基金funded by the Chinese National Basic Research Program grants(2011CB910600,2013CB911201)to Xu Ping and Li Ning respectivelythe grants of National Natural Science Foundation of China(31070673,31170780)to Xu Ping
文摘Proteomics focuses on the systematic identification and quantification of entire proteomes and interpretation of proteins’biological functions.During the last decade,proteomics in China has grown much faster than other research fields in life sciences.At the beginning of the second decade of the 21st century,the rapid development of high-resolution and high-speed mass spectrometry makes proteomics a powerful tool to study the mechanisms underlying physiological/pathological processes in organisms.This article provides a brief overview of proteomics technology development and representative scientific progress of the Human Liver Proteome Project in China over the past three years.
