功能性消化不良(functional dyspepsia, FD)是一种常见的功能性胃肠疾病,临床表现为胃脘痛或灼烧、餐后饱腹或早饱。现有研究证实针刺可有效缓解FD的临床症状,然而FD的针刺治疗机制尚无系统性阐述。本文通过查阅相关文献,整理及归纳现...功能性消化不良(functional dyspepsia, FD)是一种常见的功能性胃肠疾病,临床表现为胃脘痛或灼烧、餐后饱腹或早饱。现有研究证实针刺可有效缓解FD的临床症状,然而FD的针刺治疗机制尚无系统性阐述。本文通过查阅相关文献,整理及归纳现有相关研究,以此探讨针刺治疗FD的相关机制。经总结与分析将发现针刺治疗FD的作用机制主要包括调节胃肠动力、影响脑肠肽的表达、降低内脏高敏感性、调节脑-肠轴互动等相关因素,但尚未形成系统化研究。本文通过总结针刺治疗FD的相关机制,结合针刺起效相关可能机制,对未来FD相关机制研究提出思考与展望。Functional dyspepsia (FD) is a common functional gastrointestinal disorder, whose clinical manifestations are epigastric pain or burning, postprandial fullness or early satiety. Current studies have confirmed that acupuncture can effectively relieve the clinical symptoms of FD. However, there is no systematic elaboration on the acupuncture treatment mechanism of FD. By consulting relevant literature and collating and summarizing existing related studies, this article explores the relevant mechanisms of acupuncture treatment for FD. Through summary and analysis, it will be found that the mechanism of acupuncture in treating FD mainly includes regulating gastrointestinal motility, influencing the expression of brain-gut peptides, reducing visceral hypersensitivity, regulating the brain-gut axis interaction and other related factors, but systematic research has not yet been formed. This article summarizes the relevant mechanisms of acupuncture treatment for FD and combines the possible mechanisms related to the effect of acupuncture, and puts forward thoughts and prospects for future research on the related mechanisms of FD.展开更多
文摘功能性消化不良(functional dyspepsia, FD)是一种常见的功能性胃肠疾病,临床表现为胃脘痛或灼烧、餐后饱腹或早饱。现有研究证实针刺可有效缓解FD的临床症状,然而FD的针刺治疗机制尚无系统性阐述。本文通过查阅相关文献,整理及归纳现有相关研究,以此探讨针刺治疗FD的相关机制。经总结与分析将发现针刺治疗FD的作用机制主要包括调节胃肠动力、影响脑肠肽的表达、降低内脏高敏感性、调节脑-肠轴互动等相关因素,但尚未形成系统化研究。本文通过总结针刺治疗FD的相关机制,结合针刺起效相关可能机制,对未来FD相关机制研究提出思考与展望。Functional dyspepsia (FD) is a common functional gastrointestinal disorder, whose clinical manifestations are epigastric pain or burning, postprandial fullness or early satiety. Current studies have confirmed that acupuncture can effectively relieve the clinical symptoms of FD. However, there is no systematic elaboration on the acupuncture treatment mechanism of FD. By consulting relevant literature and collating and summarizing existing related studies, this article explores the relevant mechanisms of acupuncture treatment for FD. Through summary and analysis, it will be found that the mechanism of acupuncture in treating FD mainly includes regulating gastrointestinal motility, influencing the expression of brain-gut peptides, reducing visceral hypersensitivity, regulating the brain-gut axis interaction and other related factors, but systematic research has not yet been formed. This article summarizes the relevant mechanisms of acupuncture treatment for FD and combines the possible mechanisms related to the effect of acupuncture, and puts forward thoughts and prospects for future research on the related mechanisms of FD.
