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论司法调解制度的功能超负 被引量:5
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作者 钱大军 刘明奎 《学术交流》 CSSCI 北大核心 2017年第2期90-96,共7页
司法调解是党和国家一直倚重,并充分地发挥其功能的纠纷解决与政治合法性生产的制度。但是,面对新的社会现实,该制度功能逐渐萎缩,已不能应付大量的形态各异的纠纷。司法决策的惯性心理赋予其超出本身能力的预期。这种预期一方面基于对... 司法调解是党和国家一直倚重,并充分地发挥其功能的纠纷解决与政治合法性生产的制度。但是,面对新的社会现实,该制度功能逐渐萎缩,已不能应付大量的形态各异的纠纷。司法决策的惯性心理赋予其超出本身能力的预期。这种预期一方面基于对司法调解制度功能的盲目信任,另一方面因为司法调解运用知识的匮乏。近年来,并不理想的司法调解实践说明司法政策的确立必须符合司法制度本身的逻辑。司法调解制度的科学定位应立基于其功能限度。 展开更多
关键词 司法调解 司法政策 功能超负
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Improvement of cardiac function and reversal of gap junction remodeling by Neuregulin-1β in volume-overloaded rats with heart failure 被引量:11
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作者 Xue-Hui Wang Xiao-Zhen Zhuo +4 位作者 Ya-Juan Ni Min Gong Ting-Zhong Wang Qun Lu Ai-Qun Ma 《Journal of Geriatric Cardiology》 CAS CSCD 2012年第2期172-179,共8页
Objective We performed experiments using Neuregulin-1β (NRG-1β) treatment to determine a mechanism for the protective role derived from its beneficial effects by remodeling gap junctions (GJs) during heart failu... Objective We performed experiments using Neuregulin-1β (NRG-1β) treatment to determine a mechanism for the protective role derived from its beneficial effects by remodeling gap junctions (GJs) during heart failure (HF). Methods Rat models of I-IF were established by aortocaval fistula. Forty-eight rats were divided randomly into the HF (HF, n = 16), NRG-1β trealanent (NRG, n = 16), and sham operation (S, n = 16) group. The rats in the NRG group were administered NRG-1β (10 μg/kg per day) for 7 days via the tail vein, whereas the other groups were injected with the same doses of saline, Twelve weeks after operation, Connexin 43 (Cx43) expression in single myocytes obtained from the left ventricle was determined by immunocytochemistry. Total protein was extracted from frozen left ventricular tissues for immunoblotting assay, and the ultrastmcture of myocytes was observed by transmission electron microscopy. Results Compared with the HF group, the cardiac fimction of rats in the NRG group was markedly improved, irregular distribution and deceased Cx43 expression were relieved. The ultrastmcture of myocytes was seriously damaged in HF rats, and NRG-1β reduced these pathological damages. Conclusions Short-term NRG-1β treatment can rescue pump failure in experimental models of volume overload-induced HF, which is related to the recovery of GJs structure and the improvement of Cx43 expression. 展开更多
关键词 qeuregulin-1β Cardiac function Heart failure Connexin 43 Gap junction REMODELING
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