Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great processing flexibility are the predominant scaffolding materials. Synthetic biodegradable polymers with well-defined structure and...Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great processing flexibility are the predominant scaffolding materials. Synthetic biodegradable polymers with well-defined structure and without immunological concerns associated with naturally derived polymers are widely used in tissue engineering. The synthetic biodegradable polymers that are widely used in tissue engineering, including polyesters, polyanhydrides, polyphosphazenes, polyurethane, and poly(glycerol sebacate) are summarized in this article. New developments in conducting polymers, photoresponsive polymers, amino-acid-based polymers, enzymatically degradable polymers, and peptide-activated polymers are also discussed. In addition to chemical functionalization, the scaffold designs that mimic the nano and micro features of the extracellular matrix(ECM) are presented as well, and composite and nanocomposite scaffolds are also reviewed.展开更多
The coordination polymer poly（nickel-ethylenetetrathiolate） （poly（Ni-ett））, formed by nickel（Ⅱ） and 1,1,2,2-ethenetetrathiolate （ett）, is the most promising N-type organic thermoelectric material ever repor...The coordination polymer poly（nickel-ethylenetetrathiolate） （poly（Ni-ett））, formed by nickel（Ⅱ） and 1,1,2,2-ethenetetrathiolate （ett）, is the most promising N-type organic thermoelectric material ever reported; it is synthesized via potentiostatic deposition, and the effect of different applied potentials on the optimal performance of the polymers is investigated. The optimal thermoelectric property ofpoly（Ni-ett） synthesized at 0.6 V is remarkably greater than that of the polymers synthesized at 1 and 1.6 V, exhibiting a maximum power factor of up to 131.6μW/mK2 at 360 K. Furthermore, the structure-property correlation ofpoly（Ni-ett） is also extensively investigated. X-ray diffraction （XRD） and X-ray photoelectron spectroscopy （XPS） analyses revealed that the larger size of crystalline domains and the higher oxidation state of poly（Ni-ett） synthesized at 0.6 V possibly results in the higher bulk mobility and carrier concentration in the polymer chains, respectively, accounting for the enhanced power factor.展开更多
基金the financial support of the US National Institutes of Health(NIDCR DE015384,DE017689,DE022327)DOD(W81XWH-12-2-0008)+1 种基金the National Science Foundation of the United States(DMR-1206575)the National Natural Science Foundation of China(21304073)
文摘Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great processing flexibility are the predominant scaffolding materials. Synthetic biodegradable polymers with well-defined structure and without immunological concerns associated with naturally derived polymers are widely used in tissue engineering. The synthetic biodegradable polymers that are widely used in tissue engineering, including polyesters, polyanhydrides, polyphosphazenes, polyurethane, and poly(glycerol sebacate) are summarized in this article. New developments in conducting polymers, photoresponsive polymers, amino-acid-based polymers, enzymatically degradable polymers, and peptide-activated polymers are also discussed. In addition to chemical functionalization, the scaffold designs that mimic the nano and micro features of the extracellular matrix(ECM) are presented as well, and composite and nanocomposite scaffolds are also reviewed.
基金supported by the National Basic Research Program of China (2013CB632506)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB12000000)+1 种基金Key Project of National Natural Science Foundation of China (51336009)National Natural Science Foundation of China (21290191, 21333011)
文摘The coordination polymer poly（nickel-ethylenetetrathiolate） （poly（Ni-ett））, formed by nickel（Ⅱ） and 1,1,2,2-ethenetetrathiolate （ett）, is the most promising N-type organic thermoelectric material ever reported; it is synthesized via potentiostatic deposition, and the effect of different applied potentials on the optimal performance of the polymers is investigated. The optimal thermoelectric property ofpoly（Ni-ett） synthesized at 0.6 V is remarkably greater than that of the polymers synthesized at 1 and 1.6 V, exhibiting a maximum power factor of up to 131.6μW/mK2 at 360 K. Furthermore, the structure-property correlation ofpoly（Ni-ett） is also extensively investigated. X-ray diffraction （XRD） and X-ray photoelectron spectroscopy （XPS） analyses revealed that the larger size of crystalline domains and the higher oxidation state of poly（Ni-ett） synthesized at 0.6 V possibly results in the higher bulk mobility and carrier concentration in the polymer chains, respectively, accounting for the enhanced power factor.
