AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding ...AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding treated in Canadian hospitals. Risk scores were calculated and used to classify patients based on outcomes. For each outcome, we used χ2 goodness-of-fit tests to assess the degree of calibration, and built receiver operating characteristic curves and calculated the area under the curve (AUC) to evaluate the discriminative ability of the scoring system. RESULTS: For rebleeding, the χ2 goodness-of-fit test indicated an acceptable fit for the model [χ2 (8) = 12.83, P = 0.12]. For surgical procedures [χ2 (8) = 5.3, P = 0.73] and death [χ2 (8) = 3.78, P = 0.88], the tests showed solid correspondence between observed proportions and predicted probabilities. The AUC was 0.59 (95% CI: 0.55-0.62) for the outcome of rebleeding and 0.60 (95% CI: 0.54-0.67) for surgical procedures, representing apoor discriminative ability of the scoring system. For the outcome of death, the AUC was 0.73 (95% CI: 0.69-0.78), indicating an acceptable discriminative ability. CONCLUSION: The Rockall scoring system provides an acceptable tool to predict death, but performs poorly for endpoints of rebleeding and surgical procedures.展开更多
Although most cases of acute nonvariceal gastrointestinal hemorrhage either spontaneously resolve or respond to medical management or endoscopic treatment,there are still a significant number of patients who require e...Although most cases of acute nonvariceal gastrointestinal hemorrhage either spontaneously resolve or respond to medical management or endoscopic treatment,there are still a significant number of patients who require emergency angiography and transcatheter treatment.Evaluation with noninvasive imaging such as nuclear scintigraphy or computed tomography may localize the bleeding source and/or confirm active hemorrhage prior to angiography.Any angiographic evaluation should begin with selective catheterization of the artery supplying the most likely site of bleeding,as determined by the available clinical,endoscopic and imaging data.If a hemorrhage source is identified,superselective catheterization followed by transcatheter microcoil embolization is usually the most effective means of successfully controlling hemorrhage while minimizing potential complications.This is now wellrecognized as a viable and safe alternative to emergency surgery.In selected situations transcatheter intra-arterial infusion of vasopressin may also be useful in controlling acute gastrointestinal bleeding.One must be aware of the various side effects and potential complications associated with this treatment,however,and recognize the high re-bleeding rate.In this article we review the current role of angiography,transcatheter arterial embolization and infusion therapy in the evaluation and management of nonvariceal gastrointestinal hemorrhage.展开更多
The cashmere yarns were set in steam of 120℃ for 5 minutes after they had been extended to about 3% and wrapped onto the glass mandrels, which was relevant to the industrial setting processes. The effects of the stea...The cashmere yarns were set in steam of 120℃ for 5 minutes after they had been extended to about 3% and wrapped onto the glass mandrels, which was relevant to the industrial setting processes. The effects of the steaming on the tensile mechanical properties of cashmere fiber are investigated. The extension in ' yield region' and the extension at rupture of the set cashmere fiber are obviously decreased.展开更多
Earthquake-induced landslides along the Dujiangyan-Yingxiu highway after the Ms 8.0 Wenchuan earthquake in 2008 were investigated. It was found that： （1） slopes were shattered and damaged during the earthquake a...Earthquake-induced landslides along the Dujiangyan-Yingxiu highway after the Ms 8.0 Wenchuan earthquake in 2008 were investigated. It was found that： （1） slopes were shattered and damaged during the earthquake and open tension cracks formed on the tops of the slopes; （2） the upper parts of slopes collapsed and slid, while the lower parts remained basically intact, indicating that the upper parts of slopes would be damaged more heavily than the lower parts during an earthquake. Large-scale shaking table model tests were conducted to study failure behavior of slopes under the Wenchuan seismic wave, which reproduced the process of deformation and failure of slopes. Tension cracks emerged at the top and upper part of model, while the bottom of the model remained intact, consistent with field investigations. Depth of the tension crack at the top of model is 32 cm, i.e., 3.2 m compared to the prototype natural slope with a height of 14 m when the length scale ratio （proto/model） is lo. Acceleration at the top of the slope was almost twice as large as that at the toe when the measured accelerations on shaking table are 4.85 m/s2 and 6.49 m/s2, which means that seismic force at the top of the slope is twice the magnitude of that at the toe. By use of the dynamic-strength-reduction method, numerical simulation was conducted to explore the process and mechanism of formation of the sliding surface, with other quantified information. The earthquake-induced failure surfaces commonly consist of tension cracks and shear zones. Within 5 mfrom the top of the slope, the dynamic sliding surface will be about 1 m shallower than the pseudo-static sliding surface in a horizontal direction when the peak ground acceleration （PGA） is 1 m/s2; the dynamic sliding surface will be about 2 m deeper than the pseudo-static sliding surface in a horizontal direction when the PGA is lo m/sL and the depths of the dynamic sliding surface and the pseudo-static sliding surface will be almost the same when the PGA is 2 m/s2. Based on these findings, it is suggested that the key point of anti-seismic design, as well as for mitigation of post-earthquake, secondary mountain hazards, is to prevent tension cracks from forming in the upper part of the slope. Therefore, the depth of tension cracks in slope surfaces is the key to reinforcement of slopes. The depth of the sliding surface from the pseudo-static method can be a reference for slope reinforcement mitigation.展开更多
The enumerating algorithm has been introduced into the fitting procedure of the ASR model. Based on the detailed study of 21 large earthquakes with M≥6. 8 in the Chinese Mainland,the statistical features of seismic s...The enumerating algorithm has been introduced into the fitting procedure of the ASR model. Based on the detailed study of 21 large earthquakes with M≥6. 8 in the Chinese Mainland,the statistical features of seismic strain release before large earthquakes have been summarized. In the mass,the strain release models can be divided into five types. The first is the DA model,in which the strain release accelerates in broader areas and decelerates in small areas around the epicenter. Approximately 38% of earthquake samples are of this type. The second is the AD model,in which the strain release decelerates in broader areas and accelerates in smaller areas around the epicenter with an occupying ratioof approximately 19%. The third is ASR,in which only accelerating strain release can be observed. Cases of this model amount to about 14%. The fourth is DSR,in which only decelerating strain release can be checked,amounting to about 24%. There is only one earthquake sample of the fifth type (LSR),which shows a linear strain release. There is a 3～6 years difference in the duration of pre-shock sequences between the accelerating and decelerating models. This means that seismic quiescence against a background of increased seismicity of small earthquakes before large earthquakes are a typical feature in general. For the DA model,the average size of critical regions for steady accelerating and decelerating strain release is about 260km to 400km and 100km to 200km,respectively,3 to 5 times and 1 to 2 times the rupture size of an earthquake of magnitude 7. 0. The AD model is the opposite of the DA model. The model parameter,m value,has good stability. The ratio of ASR is about the same for accelerating seismic strain release phenomena,no matter what the strain release models are,or how large the strain release quantity is. With regard to decelerating seismic strain release phenomena, the DA model has the most distinctive decelerating strain release characteristic and is the typical feature of seismic strain release,i. e. "decelerating in-accelerating out seismic strain model".展开更多
To denoise the diffusion weighted images （DWls） featured as multi-boundary, which was very important for the calculation of accurate DTIs （diffusion tensor magnetic resonance imaging）, a modified Wiener filter was...To denoise the diffusion weighted images （DWls） featured as multi-boundary, which was very important for the calculation of accurate DTIs （diffusion tensor magnetic resonance imaging）, a modified Wiener filter was proposed. Through analyzing the widely accepted adaptive Wiener filter in image denoising fields, which suffered from annoying noise around the edges of DWIs and in turn greatly affected the denoising effect of DWIs, a local-shift method capable of overcoming the defect of the adaptive Wiener filter was proposed to help better denoising DWIs and the modified Wiener filter was constructed accordingly. To verify the denoising effect of the proposed method, the modified Wiener filter and adaptive Wiener filter were performed on the noisy DWI data, respectively, and the results of different methods were analyzed in detail and put into comparison. The experimental data show that, with the modified Wiener method, more satisfactory results such as lower non-positive tensor percentage and lower mean square errors of the fractional anisotropy map and trace map are obtained than those with the adaptive Wiener method, which in turn helps to produce more accurate DTIs.展开更多
The develop actuality and direction of FRP(fibre glass reinforced plastics) bolt in the world are analyzed The new type structure of FRP bolt was designed Trial data indicate that, all kinds of capability target o...The develop actuality and direction of FRP(fibre glass reinforced plastics) bolt in the world are analyzed The new type structure of FRP bolt was designed Trial data indicate that, all kinds of capability target of this FRP bolt all achieve and exceed the country standard, substitute present metal bolt,wood bolt and bamboo bolt and other side bolt, it can gain magnitude technology and economy benefit FRP bolt mechanization product line produce efficiency is high, its throughput a day are 750 base, this can meet demand of hit small mining company展开更多
The paper based on the proposed integrative approach to studying music cultures of the Eastern Europe. Come to light the factors of integration promoting interference and enrichment of national musical cultures. The r...The paper based on the proposed integrative approach to studying music cultures of the Eastern Europe. Come to light the factors of integration promoting interference and enrichment of national musical cultures. The region of national composer schools actively joined in world art process in the second half of the 19th century （Czechia, Poland, and Hungary） and in the 20th century （Bulgaria, Slovakia, Romania, Serbia, Slovenia, and Macedonia） Theme of this paper is to identify the basic principles of this region. The purpose of the work, defining features of the musical cultures of the Eastern European region as a whole, also here highlights the commonality of the creative ideas of representatives of the region--Bartok, Janachek, Martinu, etc.. Method of developing is defined by their orientation to the disclosure of topic. The paper used the comparative-typological and integrated approaches and methods of analysis展开更多
Objective: To study the changes and clinical significance of arginine vasopressin (AVP) and angiotensin II (AT II) in patients with acute moderate and severe cerebral injury. Methods: The early plasma concentration wa...Objective: To study the changes and clinical significance of arginine vasopressin (AVP) and angiotensin II (AT II) in patients with acute moderate and severe cerebral injury. Methods: The early plasma concentration was checked by radioimmunoassay in 47 cases of acute moderate and severe cerebral injury, 30 cases of non cerebral injury and 30 healthy volunteers. Results: The early plasma concentrations of AVP ( 50.23 ng/L± 15.31 ng/L) and AT II ( 248.18 ng/L± 82.47 ng/L) in cerebral injury group were higher than those in non cerebral injury group (AVP for 30.91 ng/L± 11.48 ng/L and AT II for 120.67 ng/L± 42.49 ng/L, P< 0.01 ). The early plasma concentrations of AVP and AT II in cerebral injury group were also obviously higher than those of the volunteers (AVP for 5.16 ng/L± 4.23 ng/L and AT II for 43.11 ng/L± 16.39 ng/L, P< 0.001 ). At the same time, the early plasma level of AVP ( 58.90 ng/L± 18.12 ng/L) and AT II ( 292.13 ng/L± 101.17 ng/L) was higher in severe cerebral injured patients than moderate cerebral injured ones (AVP for 36.68 ng/L± 12.16 ng/L and AT II for 201.42 ng/L± 66.10 ng/L, P< 0.01 ). The early level of AVP and AT II was negatively related to the GCS scales in acute cerebral injury. The early plasma concentrations of AVP ( 45.98 ng/L± 13.48 ng/L) and AT II ( 263.28 ng/L± 80.23 ng/L) were lower in epidural hematoma group than those of subdural hematoma and cerebral injury group (AVP for 64.12 ng/L± 15.56 ng/L and AT II for 319.82 ng/L± 108.11 ng/L, P< 0.01 ). Conclusions: AVP and AT II may play an important role in pathophysiologic process in the secondary cerebral injury. The more severe the cerebral injury is, the higher the early level of AVP and AT II will be. The early plasma level of AVP and AT II may be one of the severity indexes of cerebral injury.展开更多
A unilateral weighted shift A is said to be simple if its weight sequence {α_n} satisfies ▽~3(α_n^2)≠0for all n≥2.We prove that if A and B are two simple unilateral weighted shifts,then AI+IB is reducible if and ...A unilateral weighted shift A is said to be simple if its weight sequence {α_n} satisfies ▽~3(α_n^2)≠0for all n≥2.We prove that if A and B are two simple unilateral weighted shifts,then AI+IB is reducible if and only if A and B are unitarily equivalent.We also study the reducing subspaces of A^kI+IB^l and give some examples.As an application,we study the reducing subspaces of multiplication operators Mzk+αωl on function spaces.展开更多
基金Supported by the Canadian Association of Gastroenterology and an unrestricted grant from Altana Pharma Canada (formerly Byk Canada Inc.)
文摘AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding treated in Canadian hospitals. Risk scores were calculated and used to classify patients based on outcomes. For each outcome, we used χ2 goodness-of-fit tests to assess the degree of calibration, and built receiver operating characteristic curves and calculated the area under the curve (AUC) to evaluate the discriminative ability of the scoring system. RESULTS: For rebleeding, the χ2 goodness-of-fit test indicated an acceptable fit for the model [χ2 (8) = 12.83, P = 0.12]. For surgical procedures [χ2 (8) = 5.3, P = 0.73] and death [χ2 (8) = 3.78, P = 0.88], the tests showed solid correspondence between observed proportions and predicted probabilities. The AUC was 0.59 (95% CI: 0.55-0.62) for the outcome of rebleeding and 0.60 (95% CI: 0.54-0.67) for surgical procedures, representing apoor discriminative ability of the scoring system. For the outcome of death, the AUC was 0.73 (95% CI: 0.69-0.78), indicating an acceptable discriminative ability. CONCLUSION: The Rockall scoring system provides an acceptable tool to predict death, but performs poorly for endpoints of rebleeding and surgical procedures.
文摘Although most cases of acute nonvariceal gastrointestinal hemorrhage either spontaneously resolve or respond to medical management or endoscopic treatment,there are still a significant number of patients who require emergency angiography and transcatheter treatment.Evaluation with noninvasive imaging such as nuclear scintigraphy or computed tomography may localize the bleeding source and/or confirm active hemorrhage prior to angiography.Any angiographic evaluation should begin with selective catheterization of the artery supplying the most likely site of bleeding,as determined by the available clinical,endoscopic and imaging data.If a hemorrhage source is identified,superselective catheterization followed by transcatheter microcoil embolization is usually the most effective means of successfully controlling hemorrhage while minimizing potential complications.This is now wellrecognized as a viable and safe alternative to emergency surgery.In selected situations transcatheter intra-arterial infusion of vasopressin may also be useful in controlling acute gastrointestinal bleeding.One must be aware of the various side effects and potential complications associated with this treatment,however,and recognize the high re-bleeding rate.In this article we review the current role of angiography,transcatheter arterial embolization and infusion therapy in the evaluation and management of nonvariceal gastrointestinal hemorrhage.
文摘The cashmere yarns were set in steam of 120℃ for 5 minutes after they had been extended to about 3% and wrapped onto the glass mandrels, which was relevant to the industrial setting processes. The effects of the steaming on the tensile mechanical properties of cashmere fiber are investigated. The extension in ' yield region' and the extension at rupture of the set cashmere fiber are obviously decreased.
基金supported by 973 Program,Grant No. 2008CB425802National Natural Science Foundation of Chinasupported by the Fundamental Research Funds for the Central Universities (SWJTU09ZT04)
文摘Earthquake-induced landslides along the Dujiangyan-Yingxiu highway after the Ms 8.0 Wenchuan earthquake in 2008 were investigated. It was found that： （1） slopes were shattered and damaged during the earthquake and open tension cracks formed on the tops of the slopes; （2） the upper parts of slopes collapsed and slid, while the lower parts remained basically intact, indicating that the upper parts of slopes would be damaged more heavily than the lower parts during an earthquake. Large-scale shaking table model tests were conducted to study failure behavior of slopes under the Wenchuan seismic wave, which reproduced the process of deformation and failure of slopes. Tension cracks emerged at the top and upper part of model, while the bottom of the model remained intact, consistent with field investigations. Depth of the tension crack at the top of model is 32 cm, i.e., 3.2 m compared to the prototype natural slope with a height of 14 m when the length scale ratio （proto/model） is lo. Acceleration at the top of the slope was almost twice as large as that at the toe when the measured accelerations on shaking table are 4.85 m/s2 and 6.49 m/s2, which means that seismic force at the top of the slope is twice the magnitude of that at the toe. By use of the dynamic-strength-reduction method, numerical simulation was conducted to explore the process and mechanism of formation of the sliding surface, with other quantified information. The earthquake-induced failure surfaces commonly consist of tension cracks and shear zones. Within 5 mfrom the top of the slope, the dynamic sliding surface will be about 1 m shallower than the pseudo-static sliding surface in a horizontal direction when the peak ground acceleration （PGA） is 1 m/s2; the dynamic sliding surface will be about 2 m deeper than the pseudo-static sliding surface in a horizontal direction when the PGA is lo m/sL and the depths of the dynamic sliding surface and the pseudo-static sliding surface will be almost the same when the PGA is 2 m/s2. Based on these findings, it is suggested that the key point of anti-seismic design, as well as for mitigation of post-earthquake, secondary mountain hazards, is to prevent tension cracks from forming in the upper part of the slope. Therefore, the depth of tension cracks in slope surfaces is the key to reinforcement of slopes. The depth of the sliding surface from the pseudo-static method can be a reference for slope reinforcement mitigation.
基金supported by a grant from the National Key Technology R&D Program in the Eleventh"Five-year Plan"Period ( 20070403-2006BAC01B03-02-02)fund for earthquake research (200708020),China
文摘The enumerating algorithm has been introduced into the fitting procedure of the ASR model. Based on the detailed study of 21 large earthquakes with M≥6. 8 in the Chinese Mainland,the statistical features of seismic strain release before large earthquakes have been summarized. In the mass,the strain release models can be divided into five types. The first is the DA model,in which the strain release accelerates in broader areas and decelerates in small areas around the epicenter. Approximately 38% of earthquake samples are of this type. The second is the AD model,in which the strain release decelerates in broader areas and accelerates in smaller areas around the epicenter with an occupying ratioof approximately 19%. The third is ASR,in which only accelerating strain release can be observed. Cases of this model amount to about 14%. The fourth is DSR,in which only decelerating strain release can be checked,amounting to about 24%. There is only one earthquake sample of the fifth type (LSR),which shows a linear strain release. There is a 3～6 years difference in the duration of pre-shock sequences between the accelerating and decelerating models. This means that seismic quiescence against a background of increased seismicity of small earthquakes before large earthquakes are a typical feature in general. For the DA model,the average size of critical regions for steady accelerating and decelerating strain release is about 260km to 400km and 100km to 200km,respectively,3 to 5 times and 1 to 2 times the rupture size of an earthquake of magnitude 7. 0. The AD model is the opposite of the DA model. The model parameter,m value,has good stability. The ratio of ASR is about the same for accelerating seismic strain release phenomena,no matter what the strain release models are,or how large the strain release quantity is. With regard to decelerating seismic strain release phenomena, the DA model has the most distinctive decelerating strain release characteristic and is the typical feature of seismic strain release,i. e. "decelerating in-accelerating out seismic strain model".
基金Project(2009AA04Z214) supported by the National High Technology Research and Development Program of ChinaProject(07JJ6133) supported by the Natural Science Foundation of Hunan Province, China
文摘To denoise the diffusion weighted images （DWls） featured as multi-boundary, which was very important for the calculation of accurate DTIs （diffusion tensor magnetic resonance imaging）, a modified Wiener filter was proposed. Through analyzing the widely accepted adaptive Wiener filter in image denoising fields, which suffered from annoying noise around the edges of DWIs and in turn greatly affected the denoising effect of DWIs, a local-shift method capable of overcoming the defect of the adaptive Wiener filter was proposed to help better denoising DWIs and the modified Wiener filter was constructed accordingly. To verify the denoising effect of the proposed method, the modified Wiener filter and adaptive Wiener filter were performed on the noisy DWI data, respectively, and the results of different methods were analyzed in detail and put into comparison. The experimental data show that, with the modified Wiener method, more satisfactory results such as lower non-positive tensor percentage and lower mean square errors of the fractional anisotropy map and trace map are obtained than those with the adaptive Wiener method, which in turn helps to produce more accurate DTIs.
文摘The develop actuality and direction of FRP(fibre glass reinforced plastics) bolt in the world are analyzed The new type structure of FRP bolt was designed Trial data indicate that, all kinds of capability target of this FRP bolt all achieve and exceed the country standard, substitute present metal bolt,wood bolt and bamboo bolt and other side bolt, it can gain magnitude technology and economy benefit FRP bolt mechanization product line produce efficiency is high, its throughput a day are 750 base, this can meet demand of hit small mining company
文摘The paper based on the proposed integrative approach to studying music cultures of the Eastern Europe. Come to light the factors of integration promoting interference and enrichment of national musical cultures. The region of national composer schools actively joined in world art process in the second half of the 19th century （Czechia, Poland, and Hungary） and in the 20th century （Bulgaria, Slovakia, Romania, Serbia, Slovenia, and Macedonia） Theme of this paper is to identify the basic principles of this region. The purpose of the work, defining features of the musical cultures of the Eastern European region as a whole, also here highlights the commonality of the creative ideas of representatives of the region--Bartok, Janachek, Martinu, etc.. Method of developing is defined by their orientation to the disclosure of topic. The paper used the comparative-typological and integrated approaches and methods of analysis
文摘Objective: To study the changes and clinical significance of arginine vasopressin (AVP) and angiotensin II (AT II) in patients with acute moderate and severe cerebral injury. Methods: The early plasma concentration was checked by radioimmunoassay in 47 cases of acute moderate and severe cerebral injury, 30 cases of non cerebral injury and 30 healthy volunteers. Results: The early plasma concentrations of AVP ( 50.23 ng/L± 15.31 ng/L) and AT II ( 248.18 ng/L± 82.47 ng/L) in cerebral injury group were higher than those in non cerebral injury group (AVP for 30.91 ng/L± 11.48 ng/L and AT II for 120.67 ng/L± 42.49 ng/L, P< 0.01 ). The early plasma concentrations of AVP and AT II in cerebral injury group were also obviously higher than those of the volunteers (AVP for 5.16 ng/L± 4.23 ng/L and AT II for 43.11 ng/L± 16.39 ng/L, P< 0.001 ). At the same time, the early plasma level of AVP ( 58.90 ng/L± 18.12 ng/L) and AT II ( 292.13 ng/L± 101.17 ng/L) was higher in severe cerebral injured patients than moderate cerebral injured ones (AVP for 36.68 ng/L± 12.16 ng/L and AT II for 201.42 ng/L± 66.10 ng/L, P< 0.01 ). The early level of AVP and AT II was negatively related to the GCS scales in acute cerebral injury. The early plasma concentrations of AVP ( 45.98 ng/L± 13.48 ng/L) and AT II ( 263.28 ng/L± 80.23 ng/L) were lower in epidural hematoma group than those of subdural hematoma and cerebral injury group (AVP for 64.12 ng/L± 15.56 ng/L and AT II for 319.82 ng/L± 108.11 ng/L, P< 0.01 ). Conclusions: AVP and AT II may play an important role in pathophysiologic process in the secondary cerebral injury. The more severe the cerebral injury is, the higher the early level of AVP and AT II will be. The early plasma level of AVP and AT II may be one of the severity indexes of cerebral injury.
基金supported by National Natural Science Foundation of China(Grant Nos.11371096 and 11471113)
文摘A unilateral weighted shift A is said to be simple if its weight sequence {α_n} satisfies ▽~3(α_n^2)≠0for all n≥2.We prove that if A and B are two simple unilateral weighted shifts,then AI+IB is reducible if and only if A and B are unitarily equivalent.We also study the reducing subspaces of A^kI+IB^l and give some examples.As an application,we study the reducing subspaces of multiplication operators Mzk+αωl on function spaces.
