Objective: To evaluate the effectiveness of intraoperative radiotherapy (IORT) in combination with regional chemotherapy in the treatment of advanced pancreatic carcinoma.Methods: 17 patients with advanced pancreatic ...Objective: To evaluate the effectiveness of intraoperative radiotherapy (IORT) in combination with regional chemotherapy in the treatment of advanced pancreatic carcinoma.Methods: 17 patients with advanced pancreatic adenocarcinoma were treated with IORT and regional chemotherapy with 5-FU, Epirubucin and Mitomycin, and 6 cases accepted external radiotherapy postoperatively.Results: 35.29% (6/17) of the patients were clinical benefit responders and 23.53% (4/17) had a partial response. The median survival time was 11 months and the 1-year survival rate was 35.29% (6/17)Conclusion: IORT in combination with regional chemotherapy had a good impact on clinical benefit without severe side effects in locally advanced pancreatic carcinoma and led to a significant prolongation of the survival time. Key words pancreatic cancer - intraoperative radiotherapy - chemotherapy展开更多
Based on the theory of information entropy, time series and spatial variation of land use changes of Bijie City in 2009-2013 were analyzed from different dimensions such as land use degree and land use diversity. The ...Based on the theory of information entropy, time series and spatial variation of land use changes of Bijie City in 2009-2013 were analyzed from different dimensions such as land use degree and land use diversity. The result showed that in 2009-2013, the forest vegetation was well protected, and the construction land was under reasonable expansion under the influence of economic development, the land use degree of which developed gradually to width and depth, and the trend of information entropy showed a graduate increase, indicating that land use scale became more reasonable and the area of different land type became more balanced in Bijie in the period. The study results showed that land resources in Bijie City were used rationally under the strategy from central government local government,and Bijie was in the benign development of economic development—resource distribution—scale change. Moreover, Bijie chould further improve land use pattern such as redevelop stock construction land, optimize the industrial land use pattern and mountain agricultural land development in the future.展开更多
According to the analysis of the turbulent intensity level around the high-speed train, the maximum turbulent intensity ranges from 0.2 to 0.5 which belongs to high turbulent flow. The flow field distribution law was ...According to the analysis of the turbulent intensity level around the high-speed train, the maximum turbulent intensity ranges from 0.2 to 0.5 which belongs to high turbulent flow. The flow field distribution law was studied and eight types of flow regions were proposed. They are high pressure with air stagnant region, pressure decreasing with air accelerating region, low pressure with high air flow velocity region I, turbulent region, steady flow region, low pressure with high air flow velocity region II,pressure increasing with air decelerating region and wake region. The analysis of the vortex structure around the train shows that the vortex is mainly induced by structures with complex mutation and large curvature change. The head and rear of train, the underbody structure, the carriage connection section and the wake region are the main vortex generating sources while the train body with even cross-section has rare vortexes. The wake structure development law studied lays foundation for the train drag reduction.展开更多
美国区域温室气体减排行动(regional greenhouse gas initiative,RGGI)是专门针对电力行业的强制性碳总量控制与交易体系,自2009年启动以来已积累了9年的历史经验。在这期间RGGI区域电力市场经历了电源结构重组的过程,二者存在密切联系...美国区域温室气体减排行动(regional greenhouse gas initiative,RGGI)是专门针对电力行业的强制性碳总量控制与交易体系,自2009年启动以来已积累了9年的历史经验。在这期间RGGI区域电力市场经历了电源结构重组的过程,二者存在密切联系。该文首先对RGGI区域碳市场的配额分配机制、市场效益及存在缺陷进行分析,然后结合RGGI区域即美国东北部9个州的电力市场电源结构和运营交易状况,着重分析RGGI区域内碳市场与电力市场的耦合机制,为我国的碳市场和电力市场建设提供宝贵经验。展开更多
A two-feed simulated moving bed（SMB） was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone Ⅱ and zone Ⅲ is disconnected with zone IV.Two feeds are added to zones I and Ⅲ,w...A two-feed simulated moving bed（SMB） was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone Ⅱ and zone Ⅲ is disconnected with zone IV.Two feeds are added to zones I and Ⅲ,while two desorbents are added to zones Ⅱ and IV separately.The investigation on the movement of concentra-tion bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones I and Ⅲ orderly,so the streams from zones I and Ⅲ could be cut into different fractions to give the products with high purity.The two-feed SMB was used to separate α-tocopherol from its homologue mixture suc-cessfully,and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB.The solvent consumption could be reduced by reusing the middle fraction without solutes.展开更多
The spatiotemporal features of carbon and nitrogen fluxes over China between 1979 and 2015were simulated by the Atmosphere–Vegetation Interaction Model(AVIM).The carbon fluxes of gross primary production and net prim...The spatiotemporal features of carbon and nitrogen fluxes over China between 1979 and 2015were simulated by the Atmosphere–Vegetation Interaction Model(AVIM).The carbon fluxes of gross primary production and net primary production captured the distribution pattern in China better than MODIS and TRENDY data.The results for nitrogen deposition and biological nitrogen fixation show the good performance of the AVIM simulation compared with the CMIP6 and CABLE data,with a deposition rate>4 g N m-2yr-1in south China.The variation in the gross primary production and net primary production can be up to 300 and 200 g C m-2yr-1in south and southeast China,respectively,and there is a discrepancy between the AVIM and the data from MODIS and TRENDY.This shows the difficulty in simulating the carbon flux in a monsoon climate region and the importance of coupling the nitrogen–carbon fluxes.The standard deviation of nitrogen deposition and biological nitrogen fixation is simulated well by the AVIM and there is a large range in nitrogen deposition of 0.8–1.2 g N m-2yr-1in south China.The climatological mean of the fluxes performs better than the variation in the standard deviation and anomaly and this variation in the carbon–nitrogen flux is the key to decreasing bias in future modeling studies.展开更多
文摘Objective: To evaluate the effectiveness of intraoperative radiotherapy (IORT) in combination with regional chemotherapy in the treatment of advanced pancreatic carcinoma.Methods: 17 patients with advanced pancreatic adenocarcinoma were treated with IORT and regional chemotherapy with 5-FU, Epirubucin and Mitomycin, and 6 cases accepted external radiotherapy postoperatively.Results: 35.29% (6/17) of the patients were clinical benefit responders and 23.53% (4/17) had a partial response. The median survival time was 11 months and the 1-year survival rate was 35.29% (6/17)Conclusion: IORT in combination with regional chemotherapy had a good impact on clinical benefit without severe side effects in locally advanced pancreatic carcinoma and led to a significant prolongation of the survival time. Key words pancreatic cancer - intraoperative radiotherapy - chemotherapy
基金Supported by the Mutual Fund Project for Soft Science Research of Guizhou Science and Technology Department and Guizhou University of Finance and Economics(Qiankehe LH[2013]7249)~~
文摘Based on the theory of information entropy, time series and spatial variation of land use changes of Bijie City in 2009-2013 were analyzed from different dimensions such as land use degree and land use diversity. The result showed that in 2009-2013, the forest vegetation was well protected, and the construction land was under reasonable expansion under the influence of economic development, the land use degree of which developed gradually to width and depth, and the trend of information entropy showed a graduate increase, indicating that land use scale became more reasonable and the area of different land type became more balanced in Bijie in the period. The study results showed that land resources in Bijie City were used rationally under the strategy from central government local government,and Bijie was in the benign development of economic development—resource distribution—scale change. Moreover, Bijie chould further improve land use pattern such as redevelop stock construction land, optimize the industrial land use pattern and mountain agricultural land development in the future.
基金Project(U1134203)supported by the National Natural Science Foundation of China
文摘According to the analysis of the turbulent intensity level around the high-speed train, the maximum turbulent intensity ranges from 0.2 to 0.5 which belongs to high turbulent flow. The flow field distribution law was studied and eight types of flow regions were proposed. They are high pressure with air stagnant region, pressure decreasing with air accelerating region, low pressure with high air flow velocity region I, turbulent region, steady flow region, low pressure with high air flow velocity region II,pressure increasing with air decelerating region and wake region. The analysis of the vortex structure around the train shows that the vortex is mainly induced by structures with complex mutation and large curvature change. The head and rear of train, the underbody structure, the carriage connection section and the wake region are the main vortex generating sources while the train body with even cross-section has rare vortexes. The wake structure development law studied lays foundation for the train drag reduction.
文摘美国区域温室气体减排行动(regional greenhouse gas initiative,RGGI)是专门针对电力行业的强制性碳总量控制与交易体系,自2009年启动以来已积累了9年的历史经验。在这期间RGGI区域电力市场经历了电源结构重组的过程,二者存在密切联系。该文首先对RGGI区域碳市场的配额分配机制、市场效益及存在缺陷进行分析,然后结合RGGI区域即美国东北部9个州的电力市场电源结构和运营交易状况,着重分析RGGI区域内碳市场与电力市场的耦合机制,为我国的碳市场和电力市场建设提供宝贵经验。
基金Supported by the Natural Science Foundation of Ningbo,China (2009A610153)Analysis & Measurement Foundation ofZhejiang (2009F70066)Education Bureau of Ningbo,China (Jd090222)
文摘A two-feed simulated moving bed（SMB） was proposed to utilize the stationary phase more effectively.Zone I is disconnected with zone Ⅱ and zone Ⅲ is disconnected with zone IV.Two feeds are added to zones I and Ⅲ,while two desorbents are added to zones Ⅱ and IV separately.The investigation on the movement of concentra-tion bands indicated that the tail of the strong retained solute and the front of the weak retained solute were eluted from zones I and Ⅲ orderly,so the streams from zones I and Ⅲ could be cut into different fractions to give the products with high purity.The two-feed SMB was used to separate α-tocopherol from its homologue mixture suc-cessfully,and could double the productivity if both feeds were identical to the feed in the conventional four-zone SMB.The solvent consumption could be reduced by reusing the middle fraction without solutes.
基金jointly supported by the project of the National Key R&D Program of China grant No. 2018YFA0606004the National Natural Science Foundation of China grant Nos.41630532 and 41975112。
文摘The spatiotemporal features of carbon and nitrogen fluxes over China between 1979 and 2015were simulated by the Atmosphere–Vegetation Interaction Model(AVIM).The carbon fluxes of gross primary production and net primary production captured the distribution pattern in China better than MODIS and TRENDY data.The results for nitrogen deposition and biological nitrogen fixation show the good performance of the AVIM simulation compared with the CMIP6 and CABLE data,with a deposition rate>4 g N m-2yr-1in south China.The variation in the gross primary production and net primary production can be up to 300 and 200 g C m-2yr-1in south and southeast China,respectively,and there is a discrepancy between the AVIM and the data from MODIS and TRENDY.This shows the difficulty in simulating the carbon flux in a monsoon climate region and the importance of coupling the nitrogen–carbon fluxes.The standard deviation of nitrogen deposition and biological nitrogen fixation is simulated well by the AVIM and there is a large range in nitrogen deposition of 0.8–1.2 g N m-2yr-1in south China.The climatological mean of the fluxes performs better than the variation in the standard deviation and anomaly and this variation in the carbon–nitrogen flux is the key to decreasing bias in future modeling studies.
