AIM:To evaluate the therapeutic effects of abdominal decompression plus continuous regional arterial infusion(CRAI) via a drug delivery system(DDS) in severe acute pancreatitis(SAP) patients with abdominal compartment...AIM:To evaluate the therapeutic effects of abdominal decompression plus continuous regional arterial infusion(CRAI) via a drug delivery system(DDS) in severe acute pancreatitis(SAP) patients with abdominal compartment syndrome(ACS).METHODS:We presented our recent experience in 8 patients with SAP.The patients developed clinical ACS,which required abdominal decompression.During the operation,a DDS was inserted into the peripancreatic artery(the catheter was inserted from the right gastroepiploic artery until it reached the junction between the pancreaticoduodenal and gastroduodenal artery).Through this DDS,a protease inhibitor,antibiotics and octreotide were infused continuously.The duration of the regional artery infusion ranged from 8 to 41 d.The outcomes and the changes in the APACHE Ⅱ score,computed tomography(CT) severity index and intraabdominal pressure(IAP) of the patients were retrospectively evaluated.RESULTS:Eight patients with an initial APACHE Ⅱ score of 18.9(range,13-27) and a Balthazar CT severity index of 9.1(range,7-10) developed severe local and systemic complications.These patients underwent subsequent surgical decompression and CRAI therapy because of intra-abdominal hypertension(IAH).After a mean interval of 131.9 ± 72.3 d hospitalization,7 patients recovered with decreased APACHE Ⅱ scores,CT severity indexes and IAP.The mean APACHE Ⅱ score was 5.4(range,4-8),the CT severity index was 2.3(range,1-3),and IAP decreased to 7.7 mmHg(range,6-11 mmHg) 60 d after operation.One patient died of multiple organ failure 1 wk after surgery.CONCLUSION:CRAI and laparotomic decompression might be a therapeutic option for SAP patients with ACS.展开更多
In order to evaluate the ride quality of the soil compactor cab supplemented by the auxiliary hydraulic mounts (AHM), a nonlinear dynamic model of the soil compactor interacting with the off-road deformable terrain is...In order to evaluate the ride quality of the soil compactor cab supplemented by the auxiliary hydraulic mounts (AHM), a nonlinear dynamic model of the soil compactor interacting with the off-road deformable terrain is established based on Matlab/Simulink sofware. The power spectral density (PSD) and the weighted root mean square (RMS) of acceleration responses of the vertical driver s seat, the cab s pitch and roll angle are chosen as objective functions in low-frequency range. Experimental investigation is also used to verify the accuracy of the model. The influence of the damping coefficients of the AHM on the cab s ride quality is analyzed, and damping coefficients are then optimized via a genetic algorithm program. The research results show that the cab s rubber mounts added by the AHM clearly improve the ride quality under various operating conditions. Particularly, with the optimal damping coefficients of the front-end mounts c a 1,2 = 1 500 N · s/m and of the rear-end mounts c a 3,4 =2 335 N · s/m, the weighted RMS values of the driver s seat, the cab s pitch and roll angle are reduced by 22.2%, 18.8%, 58.7%, respectively. Under the condition of the vehicle travelling, with the optimal damping coefficients of c a 1,2 = 1 500 N · s/m and c a 3,4 =1 882 N · s/m, the maximum PSD values of the driver s seat, the cab s pitch and roll angle are clearly decreased by 36.7%, 54.7% and 50.6% under the condition of the vehicle working.展开更多
In order to study the dynamic action and physical effects of coal seams and gas, a simulation system for this dynamic action was developed and a physical model built in our laboratory. Using this newly built model, th...In order to study the dynamic action and physical effects of coal seams and gas, a simulation system for this dynamic action was developed and a physical model built in our laboratory. Using this newly built model, the volume of coal outbursts and the temperature during the outburst process were studied. The results show that: l) for coal seams with similar structure and com- ponents, two factors, i.e., gas pressure and ground stress affect the volume of coal outbursts, with gas pressure being the more im- portant of the two and 2) the changes in coal temperature, both its increase and decrease, are affected by ground stress and gas pressure, it is a process of change. Preliminary tests show that the system can simulate the dynamic interaction of coal and gas, which is helpful for studying the dynamic mechanism of solid-gas coupling of gas and coal.展开更多
Overheating of the engine, the transmission and the hydraulic device is a problem when the construction machinery works on plateau. To solve this problem, we proposed an electro-controlled hydraulic driving fan coolin...Overheating of the engine, the transmission and the hydraulic device is a problem when the construction machinery works on plateau. To solve this problem, we proposed an electro-controlled hydraulic driving fan cooling system (ECHDFCS). The system was applied to a 50-wheel loader. We carried out the coolant temperature simulation using fluid modeling software FLOWMASTER, followed by laboratory experiments and road tests. The results show that ECHDFCS can adjust the cooling capability of the system automatically based on machine heat dissipation requirements. The coolant temperature is consequently remained within an appropriate range. The simulation results are consistent with the experiment results when the experiment is performed on the plain, but are different from the road tests in some investigated parameters on the plateau.展开更多
In order to evaluate the performance of semi-active cab’s hydraulic mounts(SHM)of the off-road vibratory roller with the optimal fuzzy-PID(proportional integral derivative)control,a nonlinear dynamic model of the veh...In order to evaluate the performance of semi-active cab’s hydraulic mounts(SHM)of the off-road vibratory roller with the optimal fuzzy-PID(proportional integral derivative)control,a nonlinear dynamic model of the vehicle interacting with off-road terrains is established based on Matlab/Simulink software.The weighted root-mean-square(RMS)acceleration responses of the driver’s seat heave and the cab’s pitch angle are chosen as objective functions.The SHM is then optimized and analyzed via the optimal fuzzy-PID control under different operation conditions.The simulations results show that the driver’s ride comfort and the cab shaking are greatly affected by the off-road terrains under various operating conditions of the vehicle,especially at the speed from 8 to 12 km/h on a very poor terrain surface of Grenville soil ground under the vehicle travelling.With SHM using the optimal fuzzy-PID control,the driver’s ride comfort and the cab shaking are clearly improved under various operation conditions of the vehicle,particularly at the speed from 6 to 7 km/h of the vehicle traveling.展开更多
The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimen...The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimensional engine simulation code.In a first part,a CFD analysis is made in order to show the importance of the density in the modeling approach.Then,the CFD code is used,as a numerical test bench,for the pressure losses models development.These coefficients depend on the geometrical characteristics of the junction and an experimental validation is made with the use of a shock tube test bench.All the models are then included in the engine simulation code of the laboratory.The numerical calculation of unsteady compressible flow,in each pipe of the inlet and exhaust systems,is made and the calculated engine torque is compared with experimental measurements.展开更多
In order to prolong the residence time of the flow retaining in the supersonic flow, wall cavity has been widely applied in the scramjet combustor, and this affects the aerodynamic surface and imposes additional drag ...In order to prolong the residence time of the flow retaining in the supersonic flow, wall cavity has been widely applied in the scramjet combustor, and this affects the aerodynamic surface and imposes additional drag force on the hypersonic propulsion system. The two-dimensional coupled implicit Reynolds Averaged Navier-Stokes (RANS) equations and the RNG k?ε turbulent model were employed to investigate the flow fields of cavities with different geometric configurations, namely the classical rectangular, triangular and semi-circular, and the cavities with the fixed depth and length-to-depth ratio. At the same time, the drag force performances of the cavities were estimated and compared. The obtained results show that the numerical results are in very good agreement with the experimental data, and the different scales of grid make only a slight difference from the numerical results. The intensity of the trailing shock wave is much stronger than that of the leading one, and the area around the trailing edge of the cavities plays an important role in the chemical reaction in the scramjet combustor. With the fixed depth and length-to-depth ratio, the triangular cavity can strengthen the turbulent combustion in the scramjet combustor further, but impose the most additional drag force on the scramjet engine. The classical rectangular one can impose the least additional drag force on the engine, but the function of strengthening the combustion is the weakest. The influence of the semi-circular one is the moderate, but the machining process is more complex than the other two configurations.展开更多
An integrated program was established to design a combustor for a liquid rocket engine and to analyze regenerative cooling results on a preliminary design level.Properties of burnt gas from a kerosene-LOx mixture in t...An integrated program was established to design a combustor for a liquid rocket engine and to analyze regenerative cooling results on a preliminary design level.Properties of burnt gas from a kerosene-LOx mixture in the combustor and rocket performance were calculated from CEA which is the code for the calculation of chemical equilibrium.The heat transfer of regenerative cooling was analyzed by using SUPERTRAPP code for coolant properties and by one-dimensional correlations of the heat transfer coefficient from the combustor liner to the coolant.Profiles of the combustors of F-1 and RS-27A engines were designed from similar input data and the present results were compared to actual data for validation.Finally,the combustors of 30 tonf class,75 tonf class and 150 tonf class were designed from the required thrust,combustion chamber,exit pressure and mixture ratio of propellants.The wall temperature,heat flux and pressure drop were calculated for heat transfer analysis of regenerative cooling using the profiles.展开更多
In the previous researches, it is known that the swirl flow in circular pipe causes the temperature separation. Recently, it is shown that the temperature separation occurs in a vortex chamber when compressed air are ...In the previous researches, it is known that the swirl flow in circular pipe causes the temperature separation. Recently, it is shown that the temperature separation occurs in a vortex chamber when compressed air are pumped into this device from the periphery. Especially, in a cavity installed in the periphery of the chamber, the highest temperature was observed. Therefore, it is expected that this device can be used as a heat source in the engineering field. In recent researches, the mechanism of temperature separation in vortex chamber has been investigated by some researchers. However, there are few researches for the effect of diameter and volume of vortex chamber, height of central rod and position of cavity on the temperature separation. Further, no detailed physical explanation has been made for the temperature separation phenomena in the vortex chamber. In the present study, the effects of chamber configuration and position of the cavity on temperature separation in the vortex chamber were investigated experimentally.展开更多
基金Supported by the National Natural Science Foundation of China, No. 30872484
文摘AIM:To evaluate the therapeutic effects of abdominal decompression plus continuous regional arterial infusion(CRAI) via a drug delivery system(DDS) in severe acute pancreatitis(SAP) patients with abdominal compartment syndrome(ACS).METHODS:We presented our recent experience in 8 patients with SAP.The patients developed clinical ACS,which required abdominal decompression.During the operation,a DDS was inserted into the peripancreatic artery(the catheter was inserted from the right gastroepiploic artery until it reached the junction between the pancreaticoduodenal and gastroduodenal artery).Through this DDS,a protease inhibitor,antibiotics and octreotide were infused continuously.The duration of the regional artery infusion ranged from 8 to 41 d.The outcomes and the changes in the APACHE Ⅱ score,computed tomography(CT) severity index and intraabdominal pressure(IAP) of the patients were retrospectively evaluated.RESULTS:Eight patients with an initial APACHE Ⅱ score of 18.9(range,13-27) and a Balthazar CT severity index of 9.1(range,7-10) developed severe local and systemic complications.These patients underwent subsequent surgical decompression and CRAI therapy because of intra-abdominal hypertension(IAH).After a mean interval of 131.9 ± 72.3 d hospitalization,7 patients recovered with decreased APACHE Ⅱ scores,CT severity indexes and IAP.The mean APACHE Ⅱ score was 5.4(range,4-8),the CT severity index was 2.3(range,1-3),and IAP decreased to 7.7 mmHg(range,6-11 mmHg) 60 d after operation.One patient died of multiple organ failure 1 wk after surgery.CONCLUSION:CRAI and laparotomic decompression might be a therapeutic option for SAP patients with ACS.
基金The Science and Technology Support Program of Jiangsu Province(No.BE2014133)the Prospective Joint Research Program of Jiangsu Province(No.BY2014127-01)
文摘In order to evaluate the ride quality of the soil compactor cab supplemented by the auxiliary hydraulic mounts (AHM), a nonlinear dynamic model of the soil compactor interacting with the off-road deformable terrain is established based on Matlab/Simulink sofware. The power spectral density (PSD) and the weighted root mean square (RMS) of acceleration responses of the vertical driver s seat, the cab s pitch and roll angle are chosen as objective functions in low-frequency range. Experimental investigation is also used to verify the accuracy of the model. The influence of the damping coefficients of the AHM on the cab s ride quality is analyzed, and damping coefficients are then optimized via a genetic algorithm program. The research results show that the cab s rubber mounts added by the AHM clearly improve the ride quality under various operating conditions. Particularly, with the optimal damping coefficients of the front-end mounts c a 1,2 = 1 500 N · s/m and of the rear-end mounts c a 3,4 =2 335 N · s/m, the weighted RMS values of the driver s seat, the cab s pitch and roll angle are reduced by 22.2%, 18.8%, 58.7%, respectively. Under the condition of the vehicle travelling, with the optimal damping coefficients of c a 1,2 = 1 500 N · s/m and c a 3,4 =1 882 N · s/m, the maximum PSD values of the driver s seat, the cab s pitch and roll angle are clearly decreased by 36.7%, 54.7% and 50.6% under the condition of the vehicle working.
文摘In order to study the dynamic action and physical effects of coal seams and gas, a simulation system for this dynamic action was developed and a physical model built in our laboratory. Using this newly built model, the volume of coal outbursts and the temperature during the outburst process were studied. The results show that: l) for coal seams with similar structure and com- ponents, two factors, i.e., gas pressure and ground stress affect the volume of coal outbursts, with gas pressure being the more im- portant of the two and 2) the changes in coal temperature, both its increase and decrease, are affected by ground stress and gas pressure, it is a process of change. Preliminary tests show that the system can simulate the dynamic interaction of coal and gas, which is helpful for studying the dynamic mechanism of solid-gas coupling of gas and coal.
基金Funded by the Innovation Foundation of Guangzhou, P. R. China (No. 2005V42C0021)
文摘Overheating of the engine, the transmission and the hydraulic device is a problem when the construction machinery works on plateau. To solve this problem, we proposed an electro-controlled hydraulic driving fan cooling system (ECHDFCS). The system was applied to a 50-wheel loader. We carried out the coolant temperature simulation using fluid modeling software FLOWMASTER, followed by laboratory experiments and road tests. The results show that ECHDFCS can adjust the cooling capability of the system automatically based on machine heat dissipation requirements. The coolant temperature is consequently remained within an appropriate range. The simulation results are consistent with the experiment results when the experiment is performed on the plain, but are different from the road tests in some investigated parameters on the plateau.
基金The National Key Research and Development Plan(No.2019YFB2006402)
文摘In order to evaluate the performance of semi-active cab’s hydraulic mounts(SHM)of the off-road vibratory roller with the optimal fuzzy-PID(proportional integral derivative)control,a nonlinear dynamic model of the vehicle interacting with off-road terrains is established based on Matlab/Simulink software.The weighted root-mean-square(RMS)acceleration responses of the driver’s seat heave and the cab’s pitch angle are chosen as objective functions.The SHM is then optimized and analyzed via the optimal fuzzy-PID control under different operation conditions.The simulations results show that the driver’s ride comfort and the cab shaking are greatly affected by the off-road terrains under various operating conditions of the vehicle,especially at the speed from 8 to 12 km/h on a very poor terrain surface of Grenville soil ground under the vehicle travelling.With SHM using the optimal fuzzy-PID control,the driver’s ride comfort and the cab shaking are clearly improved under various operation conditions of the vehicle,particularly at the speed from 6 to 7 km/h of the vehicle traveling.
文摘The modeling of inlet and exhaust systems of internal combustion engine is very important in order to evaluate the engine performance.This paper presents new pressure losses models which can be included in a one dimensional engine simulation code.In a first part,a CFD analysis is made in order to show the importance of the density in the modeling approach.Then,the CFD code is used,as a numerical test bench,for the pressure losses models development.These coefficients depend on the geometrical characteristics of the junction and an experimental validation is made with the use of a shock tube test bench.All the models are then included in the engine simulation code of the laboratory.The numerical calculation of unsteady compressible flow,in each pipe of the inlet and exhaust systems,is made and the calculated engine torque is compared with experimental measurements.
基金supported by the National Natural Science Foundation of China (Grant No. 90816027)the Excellent Graduate Student Innovative Project of the National University of Defense Technology (Grant No. B070101)+1 种基金the Hunan Provincial Foundation for Postgraduate (Grant No. 3206)the Chinese Scholarship Council (CSC) for their financial support (Grant No. 2009611036)
文摘In order to prolong the residence time of the flow retaining in the supersonic flow, wall cavity has been widely applied in the scramjet combustor, and this affects the aerodynamic surface and imposes additional drag force on the hypersonic propulsion system. The two-dimensional coupled implicit Reynolds Averaged Navier-Stokes (RANS) equations and the RNG k?ε turbulent model were employed to investigate the flow fields of cavities with different geometric configurations, namely the classical rectangular, triangular and semi-circular, and the cavities with the fixed depth and length-to-depth ratio. At the same time, the drag force performances of the cavities were estimated and compared. The obtained results show that the numerical results are in very good agreement with the experimental data, and the different scales of grid make only a slight difference from the numerical results. The intensity of the trailing shock wave is much stronger than that of the leading one, and the area around the trailing edge of the cavities plays an important role in the chemical reaction in the scramjet combustor. With the fixed depth and length-to-depth ratio, the triangular cavity can strengthen the turbulent combustion in the scramjet combustor further, but impose the most additional drag force on the scramjet engine. The classical rectangular one can impose the least additional drag force on the engine, but the function of strengthening the combustion is the weakest. The influence of the semi-circular one is the moderate, but the machining process is more complex than the other two configurations.
基金supported by the Output-oriented Project of Collaborative Research Program with Higher Education Partners of Korea Aerospace Research Insti-tute in 2009
文摘An integrated program was established to design a combustor for a liquid rocket engine and to analyze regenerative cooling results on a preliminary design level.Properties of burnt gas from a kerosene-LOx mixture in the combustor and rocket performance were calculated from CEA which is the code for the calculation of chemical equilibrium.The heat transfer of regenerative cooling was analyzed by using SUPERTRAPP code for coolant properties and by one-dimensional correlations of the heat transfer coefficient from the combustor liner to the coolant.Profiles of the combustors of F-1 and RS-27A engines were designed from similar input data and the present results were compared to actual data for validation.Finally,the combustors of 30 tonf class,75 tonf class and 150 tonf class were designed from the required thrust,combustion chamber,exit pressure and mixture ratio of propellants.The wall temperature,heat flux and pressure drop were calculated for heat transfer analysis of regenerative cooling using the profiles.
文摘In the previous researches, it is known that the swirl flow in circular pipe causes the temperature separation. Recently, it is shown that the temperature separation occurs in a vortex chamber when compressed air are pumped into this device from the periphery. Especially, in a cavity installed in the periphery of the chamber, the highest temperature was observed. Therefore, it is expected that this device can be used as a heat source in the engineering field. In recent researches, the mechanism of temperature separation in vortex chamber has been investigated by some researchers. However, there are few researches for the effect of diameter and volume of vortex chamber, height of central rod and position of cavity on the temperature separation. Further, no detailed physical explanation has been made for the temperature separation phenomena in the vortex chamber. In the present study, the effects of chamber configuration and position of the cavity on temperature separation in the vortex chamber were investigated experimentally.