Serious accidents of mine hoists caused by high-speed sliding between friction lining and wire rope are often seen in coal mines.In order to solve this problem,we analyzed the contact characteristics between friction ...Serious accidents of mine hoists caused by high-speed sliding between friction lining and wire rope are often seen in coal mines.In order to solve this problem,we analyzed the contact characteristics between friction lining and wire rope.Then we carried out a dynamic mechanical analysis(DMA) to explain the change in mechanical properties of the friction lining as function of temperature and load frequency and found that temperature has a stronger effect on the mechanical properties than the frequency.We used multiple regression analysis to obtain the thermoviscoelastic constitutive relations of the friction lining.As well we derived the analytic solution for the thermoviscoelastic contact radius and pressure by combining the theory of viscoelastic contact mechanics with thermoviscoelastic constitutive relations.展开更多
As one of the representative contemporary Asian American poets, Li-Young Lee in his two poetry collections entitled Rose and The Cify in Which 1Love You, recuperates his fragmented family history of immigration, and r...As one of the representative contemporary Asian American poets, Li-Young Lee in his two poetry collections entitled Rose and The Cify in Which 1Love You, recuperates his fragmented family history of immigration, and reconstructs a dynamic relationship with remembrance of the past that writes about him and defines his sense of self. This paper from the multicultural perspective argues that understanding the past through understanding his godlike father, Lee not only negotiates the formation of his subjectivity and identity, but also establishes a spiritual origin and belonging not merely with his ethnic communities but with all the immigrants as well. The paper finds that the strategy he employs in his articulation of his self is marked by his excellent execution of poetic epiphany, and metonymic cannibalism.展开更多
The ACE (angiotensin converting enzyme) inhibitors are not only drugs widely prescribed drugs in cardiovascular diseases, but also potentially therapeutic agents in dementia. Based on the findings that the ACE inhib...The ACE (angiotensin converting enzyme) inhibitors are not only drugs widely prescribed drugs in cardiovascular diseases, but also potentially therapeutic agents in dementia. Based on the findings that the ACE inhibitors could activate the c-Jun N-terminal kinase signal to increase the ACE gene expression and that the Alu element of the human ACE gene involved in regulating ACE promoter activity, we aimed to investigate whether there are different pharmacogenetic responses of ACE I/D polymorphism to the ACE inhibitors in neurons. The three reporter vectors, pACEpro(0-SEAP, p-I-ACEpro-SEAP, and p-D-ACEpro-SEAP were used to examine the transcriptional activity of the vectors responding to the lisinopril treatment using a transient-transfection method in SH-SY5Y cells. Our results showed that lisinopril increased the promoter activity of an ACE gene by 16.7%. Additionally, we found the lisinopril enhanced the ACE promoter activity of the I-form vector by 17.2%, but adversely reduced that of the D-form vector by 16.8%, as compared with the respective control without the lisinopril treatment. Firstly, our findings had proved that the UD polymorphism of ACE gene contrarily responds to the ACE inhibitors in regulating the ACE expression in neurons, which provide a novel insight suggesting genetic testing to tailor the treatment regimens in AD (Alzheimer's disease) patients.展开更多
A better understanding of nitrogen (N) transformation in agricultural soils is crucial for the development of sustainable and environmental-friendly N fertilizer management and the proposal of effective N20 mitigati...A better understanding of nitrogen (N) transformation in agricultural soils is crucial for the development of sustainable and environmental-friendly N fertilizer management and the proposal of effective N20 mitigation strategies. This study aimed: i) to elucidate the seasonal dynamic of gross nitrification rate and N20 emission, ii) to determine the influence of soil conditions on the gross nitrification, and iii) to confirm the relationship between gross nitrification and N20 emissions in the soil of an apple orchard in Yantai, Northeast China. The gross nitrification rates and N20 fluxes were examined from March to October in 2009, 2010, and 2011 using the barometric process separation (BaPS) technique and the static chamber method. During the wet seasons gross nitrification rates were 1.64 times higher than those under dry season conditions. Multiple regression analysis revealed that gross nitrification rates were significantly correlated with soil temperature and soil water-filled pore space (WFPS). The relationship between gross nitrification rates and soil WFPS followed an optimum curve peaking at 60% WFPS. Nitrous oxide fluxes varied widely from March to October and were stimulated by N fertilizer application. Statistically significant positive correlations were found between gross nitrification rates and soil N20 emissions. Further evaluation indicated that gross nitrification contributed significantly to N20 formation during the dry season (about 86%) but to a lesser degree during the wet season (about 51%). Therefore, gross nitrification is a key process for the formation of N20 in soils of apple orchard ecosystems of the geographical region.展开更多
基金Projects 50875253 supported by the National Natural Science Foundation of China20060290505 by the Research Fund for the Doctoral Program of Higher Education of China+2 种基金107054 by the Key Project of Ministry of Education of ChinaBK2008127 by the Natural Science Foundation of Jiangsu ProvinceCX08B_042Z by the Scientific Innovation Program for Postgraduates in Colleges and Universities of Jiangsu Province
文摘Serious accidents of mine hoists caused by high-speed sliding between friction lining and wire rope are often seen in coal mines.In order to solve this problem,we analyzed the contact characteristics between friction lining and wire rope.Then we carried out a dynamic mechanical analysis(DMA) to explain the change in mechanical properties of the friction lining as function of temperature and load frequency and found that temperature has a stronger effect on the mechanical properties than the frequency.We used multiple regression analysis to obtain the thermoviscoelastic constitutive relations of the friction lining.As well we derived the analytic solution for the thermoviscoelastic contact radius and pressure by combining the theory of viscoelastic contact mechanics with thermoviscoelastic constitutive relations.
文摘As one of the representative contemporary Asian American poets, Li-Young Lee in his two poetry collections entitled Rose and The Cify in Which 1Love You, recuperates his fragmented family history of immigration, and reconstructs a dynamic relationship with remembrance of the past that writes about him and defines his sense of self. This paper from the multicultural perspective argues that understanding the past through understanding his godlike father, Lee not only negotiates the formation of his subjectivity and identity, but also establishes a spiritual origin and belonging not merely with his ethnic communities but with all the immigrants as well. The paper finds that the strategy he employs in his articulation of his self is marked by his excellent execution of poetic epiphany, and metonymic cannibalism.
文摘The ACE (angiotensin converting enzyme) inhibitors are not only drugs widely prescribed drugs in cardiovascular diseases, but also potentially therapeutic agents in dementia. Based on the findings that the ACE inhibitors could activate the c-Jun N-terminal kinase signal to increase the ACE gene expression and that the Alu element of the human ACE gene involved in regulating ACE promoter activity, we aimed to investigate whether there are different pharmacogenetic responses of ACE I/D polymorphism to the ACE inhibitors in neurons. The three reporter vectors, pACEpro(0-SEAP, p-I-ACEpro-SEAP, and p-D-ACEpro-SEAP were used to examine the transcriptional activity of the vectors responding to the lisinopril treatment using a transient-transfection method in SH-SY5Y cells. Our results showed that lisinopril increased the promoter activity of an ACE gene by 16.7%. Additionally, we found the lisinopril enhanced the ACE promoter activity of the I-form vector by 17.2%, but adversely reduced that of the D-form vector by 16.8%, as compared with the respective control without the lisinopril treatment. Firstly, our findings had proved that the UD polymorphism of ACE gene contrarily responds to the ACE inhibitors in regulating the ACE expression in neurons, which provide a novel insight suggesting genetic testing to tailor the treatment regimens in AD (Alzheimer's disease) patients.
基金supported by the Special Fund for Agro-scientific Research in the Public Interest of China (No. 201103003)the Earmarked Fund for China Agriculture Research System (No. CARS-28)
文摘A better understanding of nitrogen (N) transformation in agricultural soils is crucial for the development of sustainable and environmental-friendly N fertilizer management and the proposal of effective N20 mitigation strategies. This study aimed: i) to elucidate the seasonal dynamic of gross nitrification rate and N20 emission, ii) to determine the influence of soil conditions on the gross nitrification, and iii) to confirm the relationship between gross nitrification and N20 emissions in the soil of an apple orchard in Yantai, Northeast China. The gross nitrification rates and N20 fluxes were examined from March to October in 2009, 2010, and 2011 using the barometric process separation (BaPS) technique and the static chamber method. During the wet seasons gross nitrification rates were 1.64 times higher than those under dry season conditions. Multiple regression analysis revealed that gross nitrification rates were significantly correlated with soil temperature and soil water-filled pore space (WFPS). The relationship between gross nitrification rates and soil WFPS followed an optimum curve peaking at 60% WFPS. Nitrous oxide fluxes varied widely from March to October and were stimulated by N fertilizer application. Statistically significant positive correlations were found between gross nitrification rates and soil N20 emissions. Further evaluation indicated that gross nitrification contributed significantly to N20 formation during the dry season (about 86%) but to a lesser degree during the wet season (about 51%). Therefore, gross nitrification is a key process for the formation of N20 in soils of apple orchard ecosystems of the geographical region.