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应用数学的拓展——用一篇关于蛋白质分子的结构和功能的动理论发展的论文来说明 被引量:1
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作者 林家翘 《力学进展》 EI CSCD 北大核心 2003年第2期161-165,共5页
近来,人们喜欢从历史的角度来探讨数学在生物学中的应用问题.这种趋势似乎可以看作是应用数学范围逐渐拓展的一种自然现象.但它所用到的数学概念和方法与以往应用数学所用的概念和方法并无本质区别.例如,我们在本文中简单描述了如何将... 近来,人们喜欢从历史的角度来探讨数学在生物学中的应用问题.这种趋势似乎可以看作是应用数学范围逐渐拓展的一种自然现象.但它所用到的数学概念和方法与以往应用数学所用的概念和方法并无本质区别.例如,我们在本文中简单描述了如何将耗散系统中的动理学原理用于研究蛋白质分子的结构和功能.在这些研究中,传统统计物理学的概念和方法可以用来成功地建立与经验数据相对应的假设及理论. 展开更多
关键词 应用数学 耗散系统 动理学原理 蛋白质分子 分子结构 功能 湍流统计理论
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Excitonic Doppler-Rabi Oscillations in a Moving Organic Slab
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作者 姚鸣 朱卡的 +2 位作者 袁晓忠 蒋逸文 吴卓杰 《Journal of Shanghai Jiaotong university(Science)》 EI 2005年第3期285-287,共3页
It is theoretically shown that excitonic Doppler-Rabi oscillations can occur in an organic slab moving along the axis of a high-Q cavity. Due to the N enhancement of the vacuum Rabi frequency, this effect can be more ... It is theoretically shown that excitonic Doppler-Rabi oscillations can occur in an organic slab moving along the axis of a high-Q cavity. Due to the N enhancement of the vacuum Rabi frequency, this effect can be more eas ily observed than that in a moving two-level atom. 展开更多
关键词 Doppler-Rabi oscillations EXCITON organic slab
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Physicochemical bases for protein folding,dynamics,and protein-ligand binding 被引量:2
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作者 LI HuiMin XIE YueHui +1 位作者 LIU CiQuan LIU ShuQun 《Science China(Life Sciences)》 SCIE CAS 2014年第3期287-302,共16页
Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perfo... Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perform such a variety of functions has become much more intensive because the value of the genomic sequences relies on the accuracy of understanding the encoded gene products. Although the static three-dimensional structures of many proteins are known, the functions of proteins are ulti- mately governed by their dynamic characteristics, including the folding process, conformational fluctuations, molecular mo- tions, and protein-ligand interactions. In this review, the physicochemical principles underlying these dynamic processes are discussed in depth based on the free energy landscape (FEL) theory. Questions of why and how proteins fold into their native conformational states, why proteins are inherently dynamic, and how their dynamic personalities govern protein functions are answered. This paper will contribute to the understanding of structure-function relationship of proteins in the post-genome era of life science research. 展开更多
关键词 free energy landscape entropy-enthalpy non-complementarity RUGGEDNESS driving force thermodynamics kinetics
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