从《三块广告牌》中的动素模型看影片中的融合仪式

《三块广告牌》集聚幽默、荒诞、痛苦,糅合了丰富情感、多面人性,通过剧情的不断反转,打造了充满戏剧张力又引发观众深思的黑色幽默电影,赢得了热烈好评。影片按情节发展可分为三大片段,本文从动素模型视角对影片中人物间的关系和叙事结构进行深入分析,最后通过融合仪式理论,对影片宗旨进行整体阐释。

追寻的无望——“动素模型”理论下的《跨国银行》

德国导演汤姆·提克威的《跨国银行》是一部以刑侦和犯罪为主要叙事内容的影片，尽管这是他与好莱坞的第一次联姻，其镜头语言也表现的十分“好莱坞化”，但是它所表现的主题却是十分欧洲化的，这一点用格雷马斯的“动素模型”理论可以得到一次近乎完美的揭示。

民族文化产品的叙事研究——以《木府风云》《奢香夫人》为例

在民族文化产品的开发和创作过程中,叙事是一个非常重要的维度,但是其叙事则经常被忽略,这必然会使民族文化产品的故事价值与社会价值相悖,误导观众,误读主流社会价值。该论文选取《木府风云》《奢香夫人》两部收视率高、反响好,以民族历史为题材的电视剧为例,详细分析其故事各要素在两部电视剧中的对抗和冲突原理,以突显故事价值对民族文化产品的重要作用。

从格雷马斯叙事理论视域析主旋律影片《飞天》

运用格雷马斯的叙事学理论——动素模型理论分析《飞天》中不同人物的角色功能,勾勒出《飞天》的人物关系和结构逻辑。通过表现主人公不断拼搏奋斗的励志过程,阐述人类追求卓越迎难而上的深层主题。用语义方阵模型理论分析影片的内涵,旨在建构当国家集体利益与个人、家庭利益发生矛盾时,以国家利益为重实现个人价值的永恒命题。

Bronchoalveolar Lavage and Histologic Characterization of Inhaled Heparin in Asthmatic Guinea Pigs

Objective: To survey the effects of inhaled heparin on airway inflammation inguinea pigs with asthma and investigate the possible mechanism of inhaled heparin in the treatmentof asthma. Methods: The asthma in guinea pigs induced by ovalbumin was treated with inhaled heparin.The changes of cellularities in bronchoalveolar lavage (BAL) fluid and the airway walls wereexamined. Histologic examinations were also done in the guinea pig controls. Results: The number ofeosinophils, lymphocytes, and ciliated epithelial cells in the BAL fluid from the group treated withheparin was significantly lower than that of the group of asthma controls (P<0.01). Within theairway watts of the heparin treated group, the eosinophil infiltration was less prominent than thatof the group of asthma controls (P<0.001) and the number of mast cell was significantly higher thanthat of the group of asthma controls (P<0.01). Histologic examination showed that airway damages inthe heparin treated group were mild. Conclusion: Heparin can inhibit airway inflammation andalleviate airway damage in guinea pigs with asthma.

左·右

作为一部鲜明指涉当下普通人的精神困惑和情感迷惘的影片,《左右》通过讲述一个温情的故事,把对现代城市中人的生存价值的质询抛给故事的主人公与银幕外的观众。在他们左右为难的抉择中,王小帅再一次把深沉的人文关怀聚焦到了城市。

Pharmacokinetics of Native r-SAK in Rabbit's Femoral Artery Thrombosis Model

Objective: To study the pharmacokinetics of native r SAK in rabbit's femoral artery thrombosis model, the “lytic circle' method was used to determine plasma levels of r SAK. Methods: Thirty New Zealand rabbits were randomly assigned to the control (saline 10 ml, 30 min), r SAK low dose (0.25 mg/kg, 30 min), medial dose (0.50 mg/kg, 30 min), high dose (1.00 mg/kg, 30 min), single bolus (0.50 mg/kg, 2 min) and conjunctive therapy (initiated with heparin 200 U/kg, followed by infusion of r SAK 0.50 mg/kg for 30 min, and subsequently infused heparin 50 U/(kg·h) to endpoint) groups. The right femoral artery thrombosis model in rabbit was made by balloon injury, then the thrombolytic agents were infused through parallel ear vein and the blood samples were collected pre thrombolysis and at different time post thrombolysis to determine the plasma levels of r SAK by “lytic circle' method, the plasma levels of r SAK were processed by pharmacokinetic computing procedure to fit the model. Results: The plasma levels of r SAK and the diameters of lytic circles showed a pretty good linear correlation under the scope of 2.0×10 4 2.0×10 6 U/L, and the averaged recycle rate was (96.05±11.35)%(RSD =±11.82%).All peak concentration time in each infusion group was 30 min, and the peak concentrations positively correlated with the doses administrated in infusion groups(r=0.999 98, P <0.000 1). In single bolus group, Peak concentration time was 2 min, and the peak concentration reached (5.16±1.02) mg/L, which was significant higher than that in the same dose r SAK infusion group ( P <0.01). In conjunctive therapy group, the peak concentration showed no significant difference from that in the same dose r SAK infusion group ( P >0.05). The plasma levels of r SAK fit in two compartment model as processed by pharmacokinetic computing procedure in each group. Conclusion: The “lytic circle' method is a simple, practical and reliable method to determine the plasma level of r SAK, and the pharmacokinetics of native r SAK infusion fits in two compartment model in rabbit's femoral artery thrombosis model.

格雷马斯理论视域下电影《第十一回》的叙事艺术

影片《第十一回》将矛盾聚焦在多年前发生的一起刹车杀人案件中,通过戏中戏的形式,以众生相与思辨性的叙事,把舞台与现实中的人物全都呈现在银幕之上。从格雷马斯六动素模型和意义矩形的视角来看,观众能够在电影《第十一回》的叙事、细节、人物群像中找到和自己正在经历及面对的事情相似的地方。导演透过影片告诉观众,生活就像舞台,我们往往意识不到自己在表演,更顾不上思考和追寻关于真实的问题。

Gastric stimulation for weight loss

The prevalence of obesity is growing to epidemic proportions,and there is clearly a need for minimally invasive therapies with few adverse effects that allow for sustained weight loss.Behavior and lifestyle therapy are safe treatments for obesity in the short term,but the durability of the weight loss is limited.Although promising obesity drugs are in development,the currently available drugs lack efficacy or have unacceptable side effects.Surgery leads to long-term weight loss,but it is associated with morbidity and mortality.Gastric electrical stimulation(GES) has received increasing attention as a potential tool for treating obesity and gastrointestinal dysmotility disorders.GES is a promising,minimally invasive,safe,and effective method for treating obesity.External gastric pacing is aimed at alteration of the motility of the gastrointestinal tract in a way that will alter absorption due to alteration of transit time.In addition,data from animal models and preliminary data from human trials suggest a role for the gut-brain axis in the mechanism of GES.This may involve alteration of secretion of hormones associated with hunger or satiety.Patient selection for gastric stimulation therapy seems to be an important determinant of the treatment's outcome.Here,we review the current status,potential mechanisms of action,and possible future applications of gastric stimulation for obesity.

Effect of Mono- and Di-ethanolammonium Formate Ionic Liquids on the Volatility of Water, Ethanol, and Methanol

Vapor pressures were measured for six binary systems containing water, ethanol, or methanol with one of the two ionic liquids(ILs) at different component concentrations and temperatures using a quasi-static ebulliometer,with the ILs mono-ethanolammonium formate([HMEA][HCOO]) and di-ethanolammonium formate([HDEA][HCOO]).The vapor pressures of the IL-containing binary systems are well correlated using the NRTL model with an overall average absolute relative deviation(AARD) of 0.0062. The effect of ILs on the vapor pressure depression of solvents at 0.050 mole fraction of IL is that [HDEA][HCOO]>[HMEA][HCOO], and the vapor pressure lowering degree follows the order of water>methanol>ethanol. Further, the activity coefficients of three solvents(viz. water,ethanol, and methanol) for the binary systems {solvent(1) + IL(2)} predicted based on the fitted NRTL parameters at T 333.15 K indicate that the two ILs generate a negative deviation from Raoult's law for water and methanol and a positive deviation for ethanol to a varying degree, change the relative volatility of a solvent. [HMEA][HCOO]may be a promising entrainer to efficiently separate ethanol aqueous solutions by special rectification.

Cumulus-specific genes are transcriptionally silent following somatic cell nuclear transfer in a mouse model

This study investigated whether four cumulus-specific genes: follicular stimulating hormone receptor (FSHr), hyaluronan synthase 2 (Has2), prostaglandin synthase 2 (Ptgs2) and steroidogenic acute regulator protein (Star), were correctly reprogrammed to be transcriptionally silent following somatic cell nuclear transfer (SCNT) in a murine model. Cumulus cells of C57×CBA F1 female mouse were injected into enucleated oocytes, followed by activation in 10 μmol/L strontium chloride for 5 h and subsequent in vitro culture up to the blastocyst stage. Expression of cumulus-specific genes in SCNT-derived embryos at 2-cell, 4-cell and day 4.5 blastocyst stages was compared with corresponding in vivo fertilized embryos by real-time PCR. It was demonstrated that immediately after the first cell cycle, SCNT-derived 2-cell stage embryos did not express all four cumulus-specific genes, which continually remained silent at the 4-cell and blastocyst stages. It is therefore concluded that all four cumulus-specific genes were correctly reprogrammed to be silent following nuclear transfer with cumulus donor cells in the mouse model. This would imply that the poor preimplantation developmental competence of SCNT embryos derived from cumulus cells is due to incomplete reprogramming of other embryonic genes, rather than cumulus-specific genes.

7-lump kinetic model for residual oil catalytic cracking

In this paper a novel 7-lump kinetic model is proposed to describe residual oil catalytic cracking, in which coke is lumped separately for accurate prediction. The reactor block is modeled as a combination of an ideal pipe flow reactor (PFR) and a continuously stirred tank reactor (CSTR). Unit factors are designed to correct the deviation between model predictions and practical plant data and tuned by modified Levenberg-Marquardt algorithm. The parameters estimated are reliable and good agreement between the model predictions and plant observations is observed. The model helps us get good insight into the per- formance of an industrial riser reactor that would be useful for optimization of residual oil catalytic cracking.

Attenuation of graft ischemia-reperfusion injury by urinary trypsin inhibitor in mouse intestinal transplantation

AIM: Ischemia/reperfusion (I/R) injury is one of the major obstacles for intestinal transplantation (ITx). Urinary trypsin inhibitor (Ulinastatin, UTI) suppresses proteases and stabilizes lysosomal membranes. We supposed that Ulinastatin would diminish I/R injury of intestinal graft.METHODS: UTI- treated group and untreated control group were investigated by histological assessment at 1.5, 4, 24, and 72 h after ITx. Myeloperoxidase (MPO)activity was used as the activity of neutrophils, and malondialdehyde (MDA) was used as an index of lipid peroxidation. TNFα and i-NOS mRNA expression in graft tissue were measured by semi-quantitative RT-PCR.CD11b+ Gr1+ cells in graft lamina propria were analyzed by flow cytometry.RESULTS: Histological scores of the graft showed that the tissue injury was markedly attenuated by UTI treatment at different time points after ITx, with reduced MPO and MDA value in the grafts. The expression of TNFα and i-NOS mRNA was profoundly inhibited, while the infiltration of CD11b+ Gr1+ cells into the intestinal graft was decreased in UTI group.CONCLUSION: Urinary trypsin inhibitor attenuates I/R injury in mouse intestinal transplantation by reducing monocytes infiltration and down-regulation of TNFα and i-NOS mRNA expression.

Evaluation of CMU-1 preservation solutions using an isolated perfused rat liver model

AIM: CMU-1 is a new preservation solution with a low potassium concentration as well as low viscosity that is highly effective in reducing preservation injury. The purpose of this experiment is to compare the protective effect of CMU-1 solution with that of UW during cold preservation and normothermic reperfusion. METHODS: Wistar rats were divided into two groups according to different preservation solution: CMU-1 group and UW group. After 6, 12 and 24 h cold storage of rat liver in different preservation solutions, the isolated perfused rat liver model was applied to reperfuse the liver for 120 min normothermically (37 癈) with Krebs-Henseleit solution, meanwhile the pH value of the preservation solution was measured. The perfusate was sampled for the evaluation of alanine aminotransferase (ALT) and lactate dehydrogenase (LDH). At the end of the reperfusion, all of the bile product was collected, energy metabolic substrate and histological examination were performed. RESULTS: After preserving for 6 h, pH value of both groups did not change; after 12 h, both decreased but with no significant difference. After 24 h, pH value in UW solution group significantly decreased. The total adenine nucleotides level and AEC in liver tissue decreased with preservation time, but they were higher in CMU-1 group. And the amount of bile product after perfusion for 120 min in CMU-1 group was much more than that in UW group. However, there were no significant differences in ALT and LDH levels between two groups. Histology showed no difference. CONCLUSION: The preservation effect of CMU-1 solution is similar with that of UW solution. However, CMU-1 solution shows some advantages over UW solution in energy metabolism, preventing intracellular acidosis and bile product.

Support-surrounding rock relationship and top-coal movement laws in large dip angle fully-mechanized caving face

When mining the fully-mechanized longwall caving face along strike, the unstable equipment, the low top-coal recovery ratio and the difficulty in controlling surrounding rock may occur due to large dip angle. Considering the effects of strike angle on support stability, the ‘‘support-surrounding rock"mechanical models of support topple and support slip were established in this paper. On the basis, the influencing factors of support stability were analyzed and the technical measures of controlling support and surrounding rock stability were put forward. Then the loose particles simulation experiment was conducted to analyze the impacts of caving directions and methods on the top-coal recovery in large dip angle fully-mechanized caving face. Finally, the ‘‘upward sequence and double-openings doublerounds" caving technology was determined. The research results are of great scientific significance and practical values to improve large dip thick seam mining technology.

POLYNOMIAL MODEL BASED FAST FRACTIONAL PIXEL SEARCH ALGORITHM FOR H.264/AVC

This paper proposed a novel fast fractional pixel search algorithm based on polynomial model. With the analysis of distribution characteristics of motion compensation error surface inside tractional pixel searching window, the matching error is fitted with parabola along horizontal and vertical direction respectively. The proposcd searching strategy needs to check only 6 points rather than 16 or 24 points, which are used in the l lierarchical Fractional Pel Search algorithm （HFPS） for 1/4-pel and 1/8-pel Motion Estimation （ME）. The experimental results show that the proposed algorithm shows very good capability in keeping the rate distortion performance while reduces computation load to a large extent compared with HFPS algorithm.

Dynamic Model for Evaluation of Risk Factors During Work in Hot Environment

Mathematical model is developed for prediction of physiological changes in man during work in hot environment taking into consideration intensity of work, clothing and environment. To evaluate human functional state the heat stress index was calculated. Modeling researches made the conclusion that the main risk factor during work in hot environment is water losses that happens through thermoregulatory sweat evaporation. Modeling showed that in humid environment man wearing protective clothing has short time to work as water losses became more than 2% of human weight that means body dehydration. Preliminary model prediction can be used as preventive method to avoid hazard of human health.

Dynamic Evolvement of Agricultural System and Typical Patterns of Modern Agriculture in Coastal China:A Case of Suzhou

Based on dynamic theory of system, agriculture is a complex system composed by element, structure, function and development. Firstly, this paper analyzes their connotation and relationship, which could be simply described that in virtue of element integrating and structure optimizing, agricultural system may achieve multifunctionality to meet increasingly diverse demands. As a case study of Suzhou, it concludes that Suzhou has a LP-dependence on agricultural element, and the growth extent of agricultural productivity correlates to the ratio of agricultural labor reduc- ing rate to farmland reducing rate. Agricultural structure of Suzhou changed with time, and in the early 1980s and 2000s it was most notable. Correspondingly, agricultural function has experienced a succession process: 'production', 'production-living', and 'production-living-ecology'. At last, based on questionnaires and interviews, some new characteristics and problems of agricultural development in coastal developed region of China have been put forward. Meanwhile, some typical patterns of modern agriculture in Suzhou which adapt to system evolving are also brought up such as export-oriented agriculture, enterprises-leading agriculture, agricultural science and technology parks, characteristic and stereoscopic agriculture, tourism and sightseeing agriculture.

Positively selected genes of the Chinese tree shrew （Tupaia belangeri chinensis） locomotion system

While the recent release of the Chinese tree shrew （Tupaia belangeri chinensis） genome has made the tree shrew an increasingly viable experimental animal model for biomedical research, further study of the genome may facilitate new insights into the applicability of this model. For example, though the tree shrew has a rapid rate of speed and strong jumping ability, there are limited studies on its locomotion ability. In this study we used the available Chinese tree shrew genome information and compared the evolutionary pattern of 407 locomotion system related orthologs among five mammals （human, rhesus monkey, mouse, rat and dog） and the Chinese tree shrew. Our analyses identified 29 genes with significantly high co （Ka/Ks ratio） values and 48 amino acid sites in 14 genes showed significant evidence of positive selection in the Chinese tree shrew. Some of these positively selected genes, e.g. HOXA6 （homeobox A6） and AVP （arginine vasopressin）, play important roles in muscle contraction or skeletal morphogenesis. These results provide important clues in understanding the genetic bases of locomotor adaptation in the Chinese tree shrew.

Macro kinetics for synthesis of dimethyl carbonate from urea and methanol on Zn-containing catalyst

In a stainless steel autoclave,the synthesis kinetics of dimethyl carbonate(DMC) from urea and methanol was separately investigated without catalyst and with Zn-containing catalyst.Without catalyst,for the first reaction of DMC synthesis(the reaction of urea with methanol to methyl carbamate(MC)),the reaction kinetics can be described as the first order with respect to the concentrations of both methanol and urea.For the second reaction of DMC synthesis(the reaction of MC with methanol to DMC),the results exhibit characteristics of zero-order reaction.For Zn-containing catalyst,the first reaction is neglected in the kinetics model since its rate is much faster than the second reaction.The macro-kinetic parameters of the second reaction are obtained by fitting the experimental data to a pseudo-homogenous model,in which a side reaction in forming process of DMC is incorporated since it decreases the yield of DMC drastically at high temperature.The activation energy of the reaction from MC to DMC is 104 kJ/mol while that of the side reaction of DMC is 135 kJ/mol.The highest yield of DMC is 23%.