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祛脂灵对实验性高脂血症及动脉壁粥样斑块的影响 被引量:1
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作者 王汉祥 李颖 +1 位作者 张晓星 刘永烈 《中国实验方剂学杂志》 CAS 2000年第3期38-40,共3页
关键词 高脂血症 动脉壁粥样斑块 祛脂灵 中医药疗法
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Enhanced External Counterpulsation Treatment Inhibitting Advanced Atherosclerotic Plaque Progression by Augmenting the Plaque Wall Stress: An in vivo FSI Study Based on Animal Experiment 被引量:1
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作者 DU Jian-hang HUANG Liang +4 位作者 WU Gui-fu ZHENG Zhen-sheng FENG Ming-zhe DAI Gang WU Fu-jun 《Chinese Journal of Biomedical Engineering(English Edition)》 CSCD 2016年第1期1-11,共11页
Enhance extemal counterpulsation (ECP) procedure has exhbited itself to be an effective therapy for the m anagem entof ischem ic card iovascu lar diseases, However, considering that EECP significantly increases the... Enhance extemal counterpulsation (ECP) procedure has exhbited itself to be an effective therapy for the m anagem entof ischem ic card iovascu lar diseases, However, considering that EECP significantly increases the acute diastolic pressure, whether it will intervene in the chronic progression of advanced plaque causing great concern in clilical applkation, but yet rein ains elusive presently. In the current paper, a flu id-structure interface (FSI) num erical model of artery with p iaque corn ponent w as developed based on in vivo hem odynam ic m easurem entperfotm ed h a porcine model, to caku late the m echanical stresses of the plaque before and during EECP, and h lum to assess the potential effects of long-term EECP treatm ent on plaque progression. The resu Its show that E E C P augm ented the wall shear stress (WSS) and plaque w all stress (PWS) over the card lac cycles, aswell as the spacial oscillatory of W SS (WSSG ). Durhg EECP treatm ent, the PW S level respectively raised 6.82% and 6.07% in two simulation cases. The currentpilot study suggests that E E C P treatm entre ay p lay a positive effect on inh biting the conthued plaque progression by hcreashg the PW S level over the card iac cycles. Meanwhile, the plaque morphology should be taken into consideration while m aking patient- specific plan for Ion g- term E E C P treatment in clinic. 展开更多
关键词 atherosc lerosis placlue progression enhanced extemal counterpulsation (EECP) flow-structure in teraction (FSI)
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