AIM To isolate the chemical components from extracted crude of Psoralea corylifolia L. METHODS Applicate the function of molecular recognition in supramolecular chemistry, use 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 dio...AIM To isolate the chemical components from extracted crude of Psoralea corylifolia L. METHODS Applicate the function of molecular recognition in supramolecular chemistry, use 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol as the host molecule and chemical components in extracted crude of Psoralea corylifolia L. as guest molecules, which represent different from either in sort, quantity and sites of function groups or in structural topological character, 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol could selectively form inclusion compound with component endowed with interactional complementarity and isolate as crystalline from the extracted crude of Psoralea corylifolia L. RESULTS The isopsoralen as guest molecule is selectively included by 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol in inclusion crystal and removed by acetone from the inclusion compound and total yield is 0 18%. Isopsoralen is determined by UV, IR, 1HNMR and MS and its inclusion compound is determined by means of IR, powder XRD and single crystal XRD. The isolation effect is analyzed by GC/MS. CONCLUSION The method is simple and selective for isolation isopsoralen from extracted crude of Psoralea corylifolia L.展开更多
The molecular interaction of inclusion complex between βcyclodextrin(βCD)and nicotine in aqueous solutions was studied by UVVis spectrophotometric and proton nuclear magnetic resonance(1HNMR)spectrosco...The molecular interaction of inclusion complex between βcyclodextrin(βCD)and nicotine in aqueous solutions was studied by UVVis spectrophotometric and proton nuclear magnetic resonance(1HNMR)spectroscopy.It was found that the inclusion complex between βCD and nicotine can also be formed in alkaline aqueous solutions at pH=105.The result can be further proved by a competitive inclusion process using phenolphthalein as a probe.A solid with supermolecular structure of βCD/nicotine was prepared,and its powder Xray diffraction data indicated that the crystalline structure of inclusion complex is different from the original βCD crystalline structure.The result of differential scanning calorimetry(DSC)can also confirm this conclusion.展开更多
文摘AIM To isolate the chemical components from extracted crude of Psoralea corylifolia L. METHODS Applicate the function of molecular recognition in supramolecular chemistry, use 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol as the host molecule and chemical components in extracted crude of Psoralea corylifolia L. as guest molecules, which represent different from either in sort, quantity and sites of function groups or in structural topological character, 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol could selectively form inclusion compound with component endowed with interactional complementarity and isolate as crystalline from the extracted crude of Psoralea corylifolia L. RESULTS The isopsoralen as guest molecule is selectively included by 1,1,6,6 tetraphenylhexa 2,4 diyne 1,6 diol in inclusion crystal and removed by acetone from the inclusion compound and total yield is 0 18%. Isopsoralen is determined by UV, IR, 1HNMR and MS and its inclusion compound is determined by means of IR, powder XRD and single crystal XRD. The isolation effect is analyzed by GC/MS. CONCLUSION The method is simple and selective for isolation isopsoralen from extracted crude of Psoralea corylifolia L.
文摘The molecular interaction of inclusion complex between βcyclodextrin(βCD)and nicotine in aqueous solutions was studied by UVVis spectrophotometric and proton nuclear magnetic resonance(1HNMR)spectroscopy.It was found that the inclusion complex between βCD and nicotine can also be formed in alkaline aqueous solutions at pH=105.The result can be further proved by a competitive inclusion process using phenolphthalein as a probe.A solid with supermolecular structure of βCD/nicotine was prepared,and its powder Xray diffraction data indicated that the crystalline structure of inclusion complex is different from the original βCD crystalline structure.The result of differential scanning calorimetry(DSC)can also confirm this conclusion.
