Objective To evaluate the clinical and pathological features of Riedel's thyroiditis(RT),and current diagnostic and treatment methods for that disease.Methods Five RT cases identified by surgery and pathological e...Objective To evaluate the clinical and pathological features of Riedel's thyroiditis(RT),and current diagnostic and treatment methods for that disease.Methods Five RT cases identified by surgery and pathological examinations at Peking Union Medical College Hospital from 1985 to 2009 were analyzed and compared with the cases reported in the literature in terms of clinical and pathological features.Immunohistochemical staining of kappa and lambda light chains was carried out for RT tissues from all the five patients.Results All the five cases were females,aged 45-55 years.Elevation of serum thyroid autoantibodies was found in only one patient,who had longer disease duration than the others.Pathological examination revealed invasive fibrosclerosis of the thyroid follicles,thyroid capsule,and the surrounding tissues.In RT tissues,the number of cells containing lambda chains was a little higher than those containing kappa chains.Conclusions RT is a rare disease which might be more common in middle-aged females than in other populations.Pathological features include the destruction of thyroid follicle,extension into surrounding tissues by inflammatory cells and fibrous tissues.Immunohistochemical staining of kappa and lambda chains could help diagnose RT.展开更多
The drying kinetics of Roselle (Hibiscus sabdariffa L) of variety Terengganu (UMKL-1) and the quality attribution of Roselle were studied. The experiments were conducted using four different drying methods, includ...The drying kinetics of Roselle (Hibiscus sabdariffa L) of variety Terengganu (UMKL-1) and the quality attribution of Roselle were studied. The experiments were conducted using four different drying methods, including solar greenhouse drying (SD), solar greenhouse with intermittent heat pump drying (SIHP), hot air drying (HA) and heat pump drying (HP). Among the four drying methods, HP achieved the highest drying rate at a range from 0.054 g H20-(g DM)-1. rain-1 to 0.212 g H20-(g DM)-1. rain 1 while SD had the lowest drying rate, measured at 0.042 g H2O. (g DM) 1.min- 1. The analysis on colour kinetics revealed that there is no significant colour loss (p 〉 0.05) observed from HP's dried Roselle. Greater amount of flavonoid compounds i.e. protocatechuic acid was found in SD and SIHP dried finished product whereas HP's dried Roselle contains higher percentage of catechin as compared to other drying methods.展开更多
Objective: The aim of this study was to investigate the clinicopathologic features of gastric adenoma. Methods: Sixty-seven cases of adenoma diagnosis of gastric biopsy specimens using light microscopy, immunohistoc...Objective: The aim of this study was to investigate the clinicopathologic features of gastric adenoma. Methods: Sixty-seven cases of adenoma diagnosis of gastric biopsy specimens using light microscopy, immunohistochemistry, and follow-up methods were studied. Results: Histopathology of gastric adenoma characteristics: nuclear anaplasia, showing increase of nuclear volume and irregular, and the emergence of one or more nucleoli, mitotic ≤ 2/10 high power field (HPF). Structural changes in the gland: adenoma of the duct much more consistent, sometimes the size of the gland and irregular contour, might be associated with intestinal metaplasia. Increased significantly when the nuclear volume, mitotic 〉 2/10 HPF, irregular gland distortion, branched structures, suggesting the development of adenomas. Immunophenotype: tumor-associated carbohydrate antigens had a higher expression; adenomatous polyposis coli gene (APC) and carcinoembryonic antigen (CEA) expression of closely related with the formation of adenoma. Mucin muc-2 high expression was negatively correlated with muc-1 low expression, the combination of both can help to determine the development and changes in gastric adenoma. Survivin, Bcl-2, p21 and p53 protein expression rare cases, four were combined with the malignant transformation of gastric adenoma was important discriminant. Ki-67 positive cells 20%-40%, and could be used as degree of cell proliferation, a reference indicator of prognosis. Thirty-six to 49 months of follow-up results showed that cured 44.8% (30/67), there adenomatous hyperplasia 35.8% (24167), with the development of dysplasia showed 14.4% (11/67), the development of intramucosal carci- noma were 3.0% (2/67). Conclusion: Gastric adenomas occur significantly increased nuclear volume, mitotic 〉 2/10 HPF, ir- regular gland distortion, branch-like structure; immunohistochemical staining showed positive expression of muc-2 decreased, muc-1 positive expression; cell proliferation index Ki -67 〉 40%; p21, p53 protein expression occurred, suggesting a tendency to cancer, endoscopic mucosal resection should be as soon as possible.展开更多
In the south of the Ordos Basin, the oil source of the Upper Triassic Yanchang Formation is confused all the time, which affects further exploration. In this study, oil sources from the oil layers of Ch6, Ch8 and Ch9 ...In the south of the Ordos Basin, the oil source of the Upper Triassic Yanchang Formation is confused all the time, which affects further exploration. In this study, oil sources from the oil layers of Ch6, Ch8 and Ch9 are all analyzed and confirmed. Through their carbon isotope value and biomarkers, characteristics of crude oils from the Yanchang Formation are analyzed. Then, the oil–source relation is discussed, with the source rocks' features.Finally, the oil–source relation is calculated through cluster analysis. It is believed that the oils from the Yanchang Formation deposit in a similar redox environment, with weak oxidation–weak reduction, and have all entered maturity stage. Ch9 crude oil is more mature than crude oils from Ch6 and Ch8, and has more advanced plants and fewer algae. Gas chromatography(GC) and gas chromatography–mass spectrometry(GC–MS) analysis show that crude oils from Ch6 and Ch8 may come from Ch7, and Ch9 crude oil may not. Cluster analysis displays that crude oils from Ch6 and Ch8 have closer squared Euclidean distance with Ch7 source rocks than Ch9 crude oil does,indicating crude oils from Ch6 and Ch8 stem from Ch7 source rocks. And Ch9 crude oil has rather close squared Euclidean distance with Ch9 source rocks, illustrating Ch9 crude oil may be from Ch9 source rocks. This research may provide the theoretical basis for the next exploration deploy in the south of Ordos Basin.展开更多
The half-wave potentials of disperse dyes with different structures are measured, the relationship between half-wave potentials and their discharge properties is discussed, then their effect factors are studied, such ...The half-wave potentials of disperse dyes with different structures are measured, the relationship between half-wave potentials and their discharge properties is discussed, then their effect factors are studied, such as the chemical structure types and substituents of disperse dyes and technological parameters. The results indicate that the half-wave potentials of disperse dyes when reduced could be used to characterize their reducing and discharge properties.展开更多
AIM: To investigate the expressions of leptin and per- oxisome proliferator-activated receptor y (PPARG) in relation to body mass index (BMI). METHODS: We evaluated leptin and PPARG expres- sion in 30 adenomas o...AIM: To investigate the expressions of leptin and per- oxisome proliferator-activated receptor y (PPARG) in relation to body mass index (BMI). METHODS: We evaluated leptin and PPARG expres- sion in 30 adenomas over 1 cm in size by immunohisto- chemical staining. In addition, clinicopathologic features including BMI were assessed. RESULTS: PPARG and leptin expression showed a strong positive correlation (P = 0.035). The average BMI of the leptin-positive group was higher than that of the leptin-negative group (25.4 + 3.4 kg/m2 vs 22.6 + 2.4 kg/m2, P = 0.018), and leptin expression was sig- nificantly correlated with high BMI (P = 0.024). Leptinexpression was more frequently observed in intermedi- ate/high grade dysplasia than in low grade dysplasia (P = 0.030). However, PPARG expression was not cor- related with BMI and grade of dysplasia. CONCLUSION: BMI has influenced on the leptin ex- pression of colorectal adenoma. The exact mechanism underlies the strong correlation between leptin and PPARG expression needs further study.展开更多
Yulin was belong to "Hundred Yue" in ancient time, the Zhuang and Yao nationality was the indigenous people here. After the Qin and Han Dynasties, the central plains people constantly migrating to the south not only...Yulin was belong to "Hundred Yue" in ancient time, the Zhuang and Yao nationality was the indigenous people here. After the Qin and Han Dynasties, the central plains people constantly migrating to the south not only brought the advanced agricultural technology, but also a lot of Hafts customs and folk music, including the "picking flower lanterns", "tea-picking drama" and other folk music cultures which combined with the local pristine "tea plucking" folk songs, and then the "tea plucking" music culture began to have its own unique artistic features. These characteristics contributed to highlight the beauty of Yulin tea plucking opera. This article mainly discusses Yulin tea-picking Drama's rich aesthetic connotation through elaborating its music, lyrics, the theme, dancing, and clothing etc.展开更多
In this paper, we conduct theoretical review on the relationship of cross-cultural context and the English teaching from the perspective of the development of linguistics and pedagogy. To learn a foreign language is m...In this paper, we conduct theoretical review on the relationship of cross-cultural context and the English teaching from the perspective of the development of linguistics and pedagogy. To learn a foreign language is mainly used for the purpose of intercultural communication and successful communication depends on not only good language structure knowledge depends on understanding and grasp of the cultural context in communication. Diversified teaching mode should be designed according to different teaching goal. Teachers should according to the actual circumstance of various other class teaching, planning and design to reflect the personalized teaching. The words carry each other' s national culture information and reflect the national mentality of the humanities, represent the cultural background of different languages which have distinct and unique ethnic characteristics.展开更多
In this paper the author will try to discuss the experiences and narratives of three different categories of families living in Merdivenkoy, Fikirtepe, the oldest settlement and suburban area of the Anatolian side of ...In this paper the author will try to discuss the experiences and narratives of three different categories of families living in Merdivenkoy, Fikirtepe, the oldest settlement and suburban area of the Anatolian side of Istanbul, on the backdrop of urban transformation that will change the area soon. In life story narratives, these three examples give us information about the history, economic linkage, and life styles of neighboring families. The first category basically consists of the families that live in the area for a very long time, over some decades or more. Even one of them mentioned that, their family is living there for hundreds of years. The second category, which represents the biggest group living in the area, consists of families migrated from Sivas, a central Anatolian city, in the 1950s. Third category consist of Kurds migrated from eastern Anatolian villages and cities such as Mardin. Each category has different kinds of nostalgia about the past. Interviewees from the first category talk about family narratives related to the small village Merdivenk6y, Fikirtepe and the area. Mostly, they have a story of a "well off" family, structured and detailed narratives about the family history, including relations with the Ottoman Palace such as doing some sort of production for it. They seem very sensitive about the local cultural characteristics and what's going on in the area; realistic about and reconciled with what will happen as a result of slum clearance. Interviewees from the second category mostly emphasize the hardship of settling in a muddy suburban area, where once "muddy lands" now turned out to become valuable urban properties on which new and modem neighborhoods, shopping malls and office buildings will be built. They are expecting to get maximum gain out of the exchange of their small property, since they are desperately in need, because of the financial crisis situation. Although their houses with small gardens near the small industrial area are small, old, and neglected for years, they expect the most. Relatively newcomers, Kurdish people in the area talk about the good old days on the one hand and the painful stories about migration and settling on the other hand. They do not think about going back to their native lands, since here it is easier for them to find jobs in the informal economy as they live very close to central parts of the city. As a part of a larger research study focused on the experience of urban transformation, we made more than 50 interviews, trying to make a general outlook of the area, working on the dynamics of change before and after the urban transformation that had been started in June 2010. By using oral history research techniques and social science methodology, we conducted in-depth interviews with the people living in the neighborhood, made observations in the neighborhood and took photographs. The author's work is about the reflections of nostalgia in their family histories and experiences of different categories of families living in the area referring life story narratives. As far as the author can see in each group he works on, there are different contradictions related to their position in the city and conception of the area. The urban transformation presented and is perceived as a fortune for all of them, but it will have contradictory outcomes in reality for each as indicated in other examples in the world.展开更多
文摘Objective To evaluate the clinical and pathological features of Riedel's thyroiditis(RT),and current diagnostic and treatment methods for that disease.Methods Five RT cases identified by surgery and pathological examinations at Peking Union Medical College Hospital from 1985 to 2009 were analyzed and compared with the cases reported in the literature in terms of clinical and pathological features.Immunohistochemical staining of kappa and lambda light chains was carried out for RT tissues from all the five patients.Results All the five cases were females,aged 45-55 years.Elevation of serum thyroid autoantibodies was found in only one patient,who had longer disease duration than the others.Pathological examination revealed invasive fibrosclerosis of the thyroid follicles,thyroid capsule,and the surrounding tissues.In RT tissues,the number of cells containing lambda chains was a little higher than those containing kappa chains.Conclusions RT is a rare disease which might be more common in middle-aged females than in other populations.Pathological features include the destruction of thyroid follicle,extension into surrounding tissues by inflammatory cells and fibrous tissues.Immunohistochemical staining of kappa and lambda chains could help diagnose RT.
基金Supported by the Ministry of Agriculture and Agro-Based Industry(MOA),Malaysia(NER30001)
文摘The drying kinetics of Roselle (Hibiscus sabdariffa L) of variety Terengganu (UMKL-1) and the quality attribution of Roselle were studied. The experiments were conducted using four different drying methods, including solar greenhouse drying (SD), solar greenhouse with intermittent heat pump drying (SIHP), hot air drying (HA) and heat pump drying (HP). Among the four drying methods, HP achieved the highest drying rate at a range from 0.054 g H20-(g DM)-1. rain-1 to 0.212 g H20-(g DM)-1. rain 1 while SD had the lowest drying rate, measured at 0.042 g H2O. (g DM) 1.min- 1. The analysis on colour kinetics revealed that there is no significant colour loss (p 〉 0.05) observed from HP's dried Roselle. Greater amount of flavonoid compounds i.e. protocatechuic acid was found in SD and SIHP dried finished product whereas HP's dried Roselle contains higher percentage of catechin as compared to other drying methods.
文摘Objective: The aim of this study was to investigate the clinicopathologic features of gastric adenoma. Methods: Sixty-seven cases of adenoma diagnosis of gastric biopsy specimens using light microscopy, immunohistochemistry, and follow-up methods were studied. Results: Histopathology of gastric adenoma characteristics: nuclear anaplasia, showing increase of nuclear volume and irregular, and the emergence of one or more nucleoli, mitotic ≤ 2/10 high power field (HPF). Structural changes in the gland: adenoma of the duct much more consistent, sometimes the size of the gland and irregular contour, might be associated with intestinal metaplasia. Increased significantly when the nuclear volume, mitotic 〉 2/10 HPF, irregular gland distortion, branched structures, suggesting the development of adenomas. Immunophenotype: tumor-associated carbohydrate antigens had a higher expression; adenomatous polyposis coli gene (APC) and carcinoembryonic antigen (CEA) expression of closely related with the formation of adenoma. Mucin muc-2 high expression was negatively correlated with muc-1 low expression, the combination of both can help to determine the development and changes in gastric adenoma. Survivin, Bcl-2, p21 and p53 protein expression rare cases, four were combined with the malignant transformation of gastric adenoma was important discriminant. Ki-67 positive cells 20%-40%, and could be used as degree of cell proliferation, a reference indicator of prognosis. Thirty-six to 49 months of follow-up results showed that cured 44.8% (30/67), there adenomatous hyperplasia 35.8% (24167), with the development of dysplasia showed 14.4% (11/67), the development of intramucosal carci- noma were 3.0% (2/67). Conclusion: Gastric adenomas occur significantly increased nuclear volume, mitotic 〉 2/10 HPF, ir- regular gland distortion, branch-like structure; immunohistochemical staining showed positive expression of muc-2 decreased, muc-1 positive expression; cell proliferation index Ki -67 〉 40%; p21, p53 protein expression occurred, suggesting a tendency to cancer, endoscopic mucosal resection should be as soon as possible.
基金supported with funding from the National Natural Science Foundation of China(No.41173055)
文摘In the south of the Ordos Basin, the oil source of the Upper Triassic Yanchang Formation is confused all the time, which affects further exploration. In this study, oil sources from the oil layers of Ch6, Ch8 and Ch9 are all analyzed and confirmed. Through their carbon isotope value and biomarkers, characteristics of crude oils from the Yanchang Formation are analyzed. Then, the oil–source relation is discussed, with the source rocks' features.Finally, the oil–source relation is calculated through cluster analysis. It is believed that the oils from the Yanchang Formation deposit in a similar redox environment, with weak oxidation–weak reduction, and have all entered maturity stage. Ch9 crude oil is more mature than crude oils from Ch6 and Ch8, and has more advanced plants and fewer algae. Gas chromatography(GC) and gas chromatography–mass spectrometry(GC–MS) analysis show that crude oils from Ch6 and Ch8 may come from Ch7, and Ch9 crude oil may not. Cluster analysis displays that crude oils from Ch6 and Ch8 have closer squared Euclidean distance with Ch7 source rocks than Ch9 crude oil does,indicating crude oils from Ch6 and Ch8 stem from Ch7 source rocks. And Ch9 crude oil has rather close squared Euclidean distance with Ch9 source rocks, illustrating Ch9 crude oil may be from Ch9 source rocks. This research may provide the theoretical basis for the next exploration deploy in the south of Ordos Basin.
文摘The half-wave potentials of disperse dyes with different structures are measured, the relationship between half-wave potentials and their discharge properties is discussed, then their effect factors are studied, such as the chemical structure types and substituents of disperse dyes and technological parameters. The results indicate that the half-wave potentials of disperse dyes when reduced could be used to characterize their reducing and discharge properties.
基金Supported by Grant from Inje University College of Medicine(2010)
文摘AIM: To investigate the expressions of leptin and per- oxisome proliferator-activated receptor y (PPARG) in relation to body mass index (BMI). METHODS: We evaluated leptin and PPARG expres- sion in 30 adenomas over 1 cm in size by immunohisto- chemical staining. In addition, clinicopathologic features including BMI were assessed. RESULTS: PPARG and leptin expression showed a strong positive correlation (P = 0.035). The average BMI of the leptin-positive group was higher than that of the leptin-negative group (25.4 + 3.4 kg/m2 vs 22.6 + 2.4 kg/m2, P = 0.018), and leptin expression was sig- nificantly correlated with high BMI (P = 0.024). Leptinexpression was more frequently observed in intermedi- ate/high grade dysplasia than in low grade dysplasia (P = 0.030). However, PPARG expression was not cor- related with BMI and grade of dysplasia. CONCLUSION: BMI has influenced on the leptin ex- pression of colorectal adenoma. The exact mechanism underlies the strong correlation between leptin and PPARG expression needs further study.
文摘Yulin was belong to "Hundred Yue" in ancient time, the Zhuang and Yao nationality was the indigenous people here. After the Qin and Han Dynasties, the central plains people constantly migrating to the south not only brought the advanced agricultural technology, but also a lot of Hafts customs and folk music, including the "picking flower lanterns", "tea-picking drama" and other folk music cultures which combined with the local pristine "tea plucking" folk songs, and then the "tea plucking" music culture began to have its own unique artistic features. These characteristics contributed to highlight the beauty of Yulin tea plucking opera. This article mainly discusses Yulin tea-picking Drama's rich aesthetic connotation through elaborating its music, lyrics, the theme, dancing, and clothing etc.
文摘In this paper, we conduct theoretical review on the relationship of cross-cultural context and the English teaching from the perspective of the development of linguistics and pedagogy. To learn a foreign language is mainly used for the purpose of intercultural communication and successful communication depends on not only good language structure knowledge depends on understanding and grasp of the cultural context in communication. Diversified teaching mode should be designed according to different teaching goal. Teachers should according to the actual circumstance of various other class teaching, planning and design to reflect the personalized teaching. The words carry each other' s national culture information and reflect the national mentality of the humanities, represent the cultural background of different languages which have distinct and unique ethnic characteristics.
文摘In this paper the author will try to discuss the experiences and narratives of three different categories of families living in Merdivenkoy, Fikirtepe, the oldest settlement and suburban area of the Anatolian side of Istanbul, on the backdrop of urban transformation that will change the area soon. In life story narratives, these three examples give us information about the history, economic linkage, and life styles of neighboring families. The first category basically consists of the families that live in the area for a very long time, over some decades or more. Even one of them mentioned that, their family is living there for hundreds of years. The second category, which represents the biggest group living in the area, consists of families migrated from Sivas, a central Anatolian city, in the 1950s. Third category consist of Kurds migrated from eastern Anatolian villages and cities such as Mardin. Each category has different kinds of nostalgia about the past. Interviewees from the first category talk about family narratives related to the small village Merdivenk6y, Fikirtepe and the area. Mostly, they have a story of a "well off" family, structured and detailed narratives about the family history, including relations with the Ottoman Palace such as doing some sort of production for it. They seem very sensitive about the local cultural characteristics and what's going on in the area; realistic about and reconciled with what will happen as a result of slum clearance. Interviewees from the second category mostly emphasize the hardship of settling in a muddy suburban area, where once "muddy lands" now turned out to become valuable urban properties on which new and modem neighborhoods, shopping malls and office buildings will be built. They are expecting to get maximum gain out of the exchange of their small property, since they are desperately in need, because of the financial crisis situation. Although their houses with small gardens near the small industrial area are small, old, and neglected for years, they expect the most. Relatively newcomers, Kurdish people in the area talk about the good old days on the one hand and the painful stories about migration and settling on the other hand. They do not think about going back to their native lands, since here it is easier for them to find jobs in the informal economy as they live very close to central parts of the city. As a part of a larger research study focused on the experience of urban transformation, we made more than 50 interviews, trying to make a general outlook of the area, working on the dynamics of change before and after the urban transformation that had been started in June 2010. By using oral history research techniques and social science methodology, we conducted in-depth interviews with the people living in the neighborhood, made observations in the neighborhood and took photographs. The author's work is about the reflections of nostalgia in their family histories and experiences of different categories of families living in the area referring life story narratives. As far as the author can see in each group he works on, there are different contradictions related to their position in the city and conception of the area. The urban transformation presented and is perceived as a fortune for all of them, but it will have contradictory outcomes in reality for each as indicated in other examples in the world.