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猴D型逆转录病毒和猴艾滋病 被引量:6
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作者 陈志斌 贲昆龙 《Zoological Research》 CAS CSCD 1992年第2期193-199,共7页
1983年在加里福利亚和新英格兰灵长类研究中心先后发现了与人艾滋病的表现相似的猴艾滋病(Smian AIDS,SAIDS)(Letvin et al.,1983;Henrickson et al.,1983)。引起SAIDS的病原体有猴艾滋病D型逆转病毒(Simian AIDS Type D)Retrovirus,SRV... 1983年在加里福利亚和新英格兰灵长类研究中心先后发现了与人艾滋病的表现相似的猴艾滋病(Smian AIDS,SAIDS)(Letvin et al.,1983;Henrickson et al.,1983)。引起SAIDS的病原体有猴艾滋病D型逆转病毒(Simian AIDS Type D)Retrovirus,SRV)和猴免疫缺陷病毒(Simian Immunodefiency Virus,SIV)。 展开更多
关键词 区滋病 D型逆转 理诊断
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氟康唑体外诱导新型隐球菌耐药株的实验研究 被引量:3
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作者 苏逸丹 章强强 +2 位作者 汪师贞 翁心华 李莉 《新疆医科大学学报》 CAS 2000年第1期37-40,共4页
摸索体外诱导真菌耐药突变菌落的经济、简便的方法,为进行耐药性研究提供实验模型。方法:对所收集的34株新型隐球菌临床分离株参照美国国家临床实验室标准化委员会(NCCLS)推荐的M27-A方案,采用微量稀释法测定了其氟康... 摸索体外诱导真菌耐药突变菌落的经济、简便的方法,为进行耐药性研究提供实验模型。方法:对所收集的34株新型隐球菌临床分离株参照美国国家临床实验室标准化委员会(NCCLS)推荐的M27-A方案,采用微量稀释法测定了其氟康唑最低抑菌浓度(MIC),选出2株敏感株(MIC=4ug/ml)HS17061、HS16532和1株标准株BLS109作为实验原始菌株,经在不同浓度氟康唑的培养基中连续传代培养处理,诱导产生耐药突变菌落。结果:经传代培养,获得了抗不同浓度氟康唑的耐药突变菌落,且突变菌落氟康唑的耐药性是稳定的。结论:通过采用以不同氟康唑浓度梯度连续传代培养的方法可诱导产生氟康唑耐药株,遗传稳定性测定表明耐药突变菌落的抗氟康唑特性是稳定的,本方法可为进行耐药前后的对比研究提供可靠的实验模型。 展开更多
关键词 新型隐球菌 氟康唑 诱导 耐药性 区滋病
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Study on AIDS Epidemic from Unsafe Blood Handling among Rural Doctors
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作者 叶恒波 李倩 +2 位作者 白玥 金建强 卢祖洵 《Chinese Journal of Sexually Transmitted Infections》 2004年第1期36-39,64,共5页
Objectives: This paper examines the basic knowledge ofAIDS and HIV transmission through unsafe blood collec-tion and supply among rural Chinese doctors. It also ex-plores the accessibility of AIDS intervention methods... Objectives: This paper examines the basic knowledge ofAIDS and HIV transmission through unsafe blood collec-tion and supply among rural Chinese doctors. It also ex-plores the accessibility of AIDS intervention methods inrural area. Methods: We did Case studies, held focus group discus-sions and provided questionnaires to all rural doctors inone township where the epidemic of HIV was known to bespread through blood collection and supply. Data were col-lected and analyzed with software EPI 6.0.Results: The effective response rate to the questionnairewas 100%. The results showed that more than 95% of in-formants gave correct answers to the questions about thesexual and blood-bourne transmission of HIV as well as itscontagiousness. Half of the participants were ignorant aboutmother to child transmission of HIV and did not know thatHIV couldn’t be transmitted by saliva, sweat, mosquito bites,sharing of bathtubs or toilets. More than 80% of infor-mants were opposed to blood selling and reportedly under-stood the objective of the blood organizers in their villages,knew the peak time of blood selling by the villagers, and ,were aware of the risks of diseases being spread throughblood. . 27.3% used disposable syringes ‘once in a while’,and 15.2% discarded or sold used disposable syringes.Conclusions: The authors assert that there are severe lurk-ing perils of iatrogenic cross infection in rural areas. Ruraldoctors urgently need formal training on prevention andtreatment of HIV infection. We believe that rural doctorsshould become the key force in AIDS prevention and con-trol in rural area. 展开更多
关键词 AIDS Blood handling Rural doctor
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