Meckel's diverticulum(MD) is the most frequent congenital abnormality of the small bowel and it is often diff icult to diagnose.It is usually asymptomatic but approximately 4% are symptomatic with complications su...Meckel's diverticulum(MD) is the most frequent congenital abnormality of the small bowel and it is often diff icult to diagnose.It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding,intestinal obstruction,and inflammation.The authors report a case of a 7-year-old boy with a one-year history of recurrent periumbilical colicky pain with associated alimentary vomiting,symptoms erroneously related to a cyclic vomiting syndrome but not to MD.The clinical features and the differential diagnostic methods employed for diagnosis of MD are discussed.展开更多
AIM:To investigate the spatial distribution patterns of anorectal atresia/stenosis in China.METHODS:Data were collected from the Chinese Birth Defects Monitoring Network(CBDMN),a hospital-based congenital malformation...AIM:To investigate the spatial distribution patterns of anorectal atresia/stenosis in China.METHODS:Data were collected from the Chinese Birth Defects Monitoring Network(CBDMN),a hospital-based congenital malformations registry system.All fetuses more than 28 wk of gestation and neonates up to 7 d of age in hospitals within the monitoring sites of the CBDMN were monitored from 2001 to 2005.Two-dimensional graph-theoretical clustering was used to divide monitoring sites of the CBDMN into different clusters according to the average incidences of anorectal atresia/stenosis in the different monitoring sites.RESULTS:The overall average incidence of anorectal atresia/stenosis in China was 3.17 per 10000 from 2001 to 2005.The areas with the highest average incidences of anorectal atresia/stenosis were almost always focused in Eastern China.The monitoring sites were grouped into 6 clusters of areas.Cluster 1 comprised the monitoring sites in Heilongjiang Province,Jilin Province,and Liaoning Province;Cluster 2 was composed of those in Fujian Province,Guangdong Province,Hainan Province,Guangxi Zhuang Autonomous Region,south Hunan Province,and south Jiangxi Province;Cluster 3 consisted of those in Beijing Municipal City,Tianjin Municipal City,Hebei Province,Shandong Province,north Jiangsu Province,and north Anhui Province;Cluster 4 was made up of those in Zhejiang Province,Shanghai Municipal City,south Anhui Province,south Jiangsu Province,north Hunan Province,north Jiangxi Province,Hubei Province,Henan Province,Shanxi Province and Inner Mongolia Autonomous Region;Cluster 5 consisted of those in Ningxia Hui Autonomous Region,Gansu Province and Qinghai Province;and Cluster 6 included those in Shaanxi Province,Sichuan Province,Chongqing Municipal City,Yunnan Province,Guizhou Province,Xinjiang Uygur Autonomous Province and Tibet Autonomous Region.CONCLUSION:The fi ndings in this research allow the display of the spatial distribution patterns of anorectal atresia/stenosis in China.These will have important guiding significance for further analysis of relevant environmental factors regarding anorectal atresia/ stenosis and for achieving regional monitoring for anorectal atresia/stenosis.展开更多
This study presents statistical results of a comparison between English abstracts in a leading intemational medical journal and those in a Chinese one. With a genre analysis and discussion of linguistic features of th...This study presents statistical results of a comparison between English abstracts in a leading intemational medical journal and those in a Chinese one. With a genre analysis and discussion of linguistic features of these abstracts, the paper points out the weak points in the abstracts by Chinese writers and provides some suggestions for writing abstracts of medical research articles展开更多
Purpose： To evaluate the implementation of a pharmacy-led tobacco cessation medication education protocol at discharge in a community hospital. Design： Single center, retrospective quality assessment study. Methods...Purpose： To evaluate the implementation of a pharmacy-led tobacco cessation medication education protocol at discharge in a community hospital. Design： Single center, retrospective quality assessment study. Methods： A retrospective review of a pharmacy-led protocol was completed from November 2016 through April 2017. Data from one year prior to implementation of the protocol was analyzed against the study group. Results： A total of 607 tobacco cessation medication education interventions were made during the study period, 379 patients （62.4%） were given an OTC （Over The Counter） NRT （Nicotine Replacement Therapy） recommendation upon discharge and 148 （24.4%） were referred to the Ohio Tobacco Quit Line. TJC （The Joint Commission） TOB-3/3a measure was met in 44.1% of patients during the study period compared to 0% in the comparator group. Of the 75 patients who were reached via follow-up phone call, 23 （30.7%） purchased an OTC NRT and 22 （29.3%） completely quit using tobacco. Conclusions： Pharmacy-led tobacco cessation interventions during hospitalizations have a positive impact on TJC TOB-3/3a quality measure results and quit rates post-discharge. Our results encourage future studies in this area to further establish the importance of pharmacist involvement in tobacco cessation, specifically in the hospital setting.展开更多
Objective： To assess the medical community＇s awareness and practice regarding delirium in the intensive care unit （ICU）. Methods： One hundred and ten predesigned questionnaires were distributed to ICU practition...Objective： To assess the medical community＇s awareness and practice regarding delirium in the intensive care unit （ICU）. Methods： One hundred and ten predesigned questionnaires were distributed to ICU practitioners in the affiliated hospitals of Zhejiang University. Results： A total of 105 valid questionnaires were collected. Totally, 55.3% of the clinicians considered that delirium was common in the ICU. Delirium was believed to be a significant or serious problem by 70.5% of respondents, and under-diagnosis was acknowledged by 56.2% of the respondents. The incidence of ICU delirium is even more under-estimated by the pediatric doctors compared with their counterparts in adult ICU （P〈0.05）. Primary disease of the brain （agreed by 82.1% of the respondents） was believed to be the most common risk factor for delirium. None of the ICU professionals screened delirium or used a specific tool for delirium assessment routinely. The vast majority （92.4%） of respondents had little knowledge on the diagnosis and the standard treatment of delirium. Conclusions： Although delirium is considered as a serious problem by a majority of the surveyed ICU professionals, it is still under-recognized in routine critical care practice. Data from this survey show a disconnection between the perceived significance of delirium and the current practices of monitoring and treatment in ICU in China.展开更多
Electronic skins and flexible pressure sensors are important devices for advanced healthcare and intelligent robotics.Sensitivity is a key parameter of flexible pressure sensors.Whereas introducing surface microstruct...Electronic skins and flexible pressure sensors are important devices for advanced healthcare and intelligent robotics.Sensitivity is a key parameter of flexible pressure sensors.Whereas introducing surface microstructures in a capacitive-type sensor can significantly improve its sensitivity,the signal becomes nonlinear and the pressure response range gets much narrower,significantly limiting the applications of flexible pressure sensors.Here,we designed a pressure sensor that utilizes a nanoscale iontronic interface of an ionic gel layer and a micropillared electrode,for highly linear capacitance-to-pressure response and high sensitivity over a wide pressure range.The micropillars undergo three stages of deformation upon loading:initial contact(0-6 k Pa)and structure buckling(6-12 k Pa)that exhibit a low and nonlinear response,as well as a post-buckling stage that has a high signal linearity with high sensitivity(33.16 k Pa-1)over a broad pressure range of 12-176 k Pa.The high linearity lies in the subtle balance between the structure compression and mechanical matching of the two materials at the gel-electrode interface.Our sensor has been applied in pulse detection,plantar pressure mapping,and grasp task of an artificial limb.This work provides a physical insight in achieving linear response through the design of appropriate microstructures and selection of materials with suitable modulus in flexible pressure sensors,which are potentially useful in intelligent robots and health monitoring.展开更多
文摘Meckel's diverticulum(MD) is the most frequent congenital abnormality of the small bowel and it is often diff icult to diagnose.It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding,intestinal obstruction,and inflammation.The authors report a case of a 7-year-old boy with a one-year history of recurrent periumbilical colicky pain with associated alimentary vomiting,symptoms erroneously related to a cyclic vomiting syndrome but not to MD.The clinical features and the differential diagnostic methods employed for diagnosis of MD are discussed.
基金Supported by The National Science & Technology Pillar Program during the Eleventh Five-year Plan Period, Grant No. 2006BAI05A01
文摘AIM:To investigate the spatial distribution patterns of anorectal atresia/stenosis in China.METHODS:Data were collected from the Chinese Birth Defects Monitoring Network(CBDMN),a hospital-based congenital malformations registry system.All fetuses more than 28 wk of gestation and neonates up to 7 d of age in hospitals within the monitoring sites of the CBDMN were monitored from 2001 to 2005.Two-dimensional graph-theoretical clustering was used to divide monitoring sites of the CBDMN into different clusters according to the average incidences of anorectal atresia/stenosis in the different monitoring sites.RESULTS:The overall average incidence of anorectal atresia/stenosis in China was 3.17 per 10000 from 2001 to 2005.The areas with the highest average incidences of anorectal atresia/stenosis were almost always focused in Eastern China.The monitoring sites were grouped into 6 clusters of areas.Cluster 1 comprised the monitoring sites in Heilongjiang Province,Jilin Province,and Liaoning Province;Cluster 2 was composed of those in Fujian Province,Guangdong Province,Hainan Province,Guangxi Zhuang Autonomous Region,south Hunan Province,and south Jiangxi Province;Cluster 3 consisted of those in Beijing Municipal City,Tianjin Municipal City,Hebei Province,Shandong Province,north Jiangsu Province,and north Anhui Province;Cluster 4 was made up of those in Zhejiang Province,Shanghai Municipal City,south Anhui Province,south Jiangsu Province,north Hunan Province,north Jiangxi Province,Hubei Province,Henan Province,Shanxi Province and Inner Mongolia Autonomous Region;Cluster 5 consisted of those in Ningxia Hui Autonomous Region,Gansu Province and Qinghai Province;and Cluster 6 included those in Shaanxi Province,Sichuan Province,Chongqing Municipal City,Yunnan Province,Guizhou Province,Xinjiang Uygur Autonomous Province and Tibet Autonomous Region.CONCLUSION:The fi ndings in this research allow the display of the spatial distribution patterns of anorectal atresia/stenosis in China.These will have important guiding significance for further analysis of relevant environmental factors regarding anorectal atresia/ stenosis and for achieving regional monitoring for anorectal atresia/stenosis.
基金Supported by the Scientific Research Project(Humanities and Social Sciences)in 2012 Granted by the Education Department of Shaanxi Provincial Government(12JK0268)
文摘This study presents statistical results of a comparison between English abstracts in a leading intemational medical journal and those in a Chinese one. With a genre analysis and discussion of linguistic features of these abstracts, the paper points out the weak points in the abstracts by Chinese writers and provides some suggestions for writing abstracts of medical research articles
文摘Purpose： To evaluate the implementation of a pharmacy-led tobacco cessation medication education protocol at discharge in a community hospital. Design： Single center, retrospective quality assessment study. Methods： A retrospective review of a pharmacy-led protocol was completed from November 2016 through April 2017. Data from one year prior to implementation of the protocol was analyzed against the study group. Results： A total of 607 tobacco cessation medication education interventions were made during the study period, 379 patients （62.4%） were given an OTC （Over The Counter） NRT （Nicotine Replacement Therapy） recommendation upon discharge and 148 （24.4%） were referred to the Ohio Tobacco Quit Line. TJC （The Joint Commission） TOB-3/3a measure was met in 44.1% of patients during the study period compared to 0% in the comparator group. Of the 75 patients who were reached via follow-up phone call, 23 （30.7%） purchased an OTC NRT and 22 （29.3%） completely quit using tobacco. Conclusions： Pharmacy-led tobacco cessation interventions during hospitalizations have a positive impact on TJC TOB-3/3a quality measure results and quit rates post-discharge. Our results encourage future studies in this area to further establish the importance of pharmacist involvement in tobacco cessation, specifically in the hospital setting.
文摘Objective： To assess the medical community＇s awareness and practice regarding delirium in the intensive care unit （ICU）. Methods： One hundred and ten predesigned questionnaires were distributed to ICU practitioners in the affiliated hospitals of Zhejiang University. Results： A total of 105 valid questionnaires were collected. Totally, 55.3% of the clinicians considered that delirium was common in the ICU. Delirium was believed to be a significant or serious problem by 70.5% of respondents, and under-diagnosis was acknowledged by 56.2% of the respondents. The incidence of ICU delirium is even more under-estimated by the pediatric doctors compared with their counterparts in adult ICU （P〈0.05）. Primary disease of the brain （agreed by 82.1% of the respondents） was believed to be the most common risk factor for delirium. None of the ICU professionals screened delirium or used a specific tool for delirium assessment routinely. The vast majority （92.4%） of respondents had little knowledge on the diagnosis and the standard treatment of delirium. Conclusions： Although delirium is considered as a serious problem by a majority of the surveyed ICU professionals, it is still under-recognized in routine critical care practice. Data from this survey show a disconnection between the perceived significance of delirium and the current practices of monitoring and treatment in ICU in China.
基金supported by the Science Technology and Innovation Committee of Shenzhen Municipality(JCYJ20170817111714314)the National Natural Science Foundation of China(52073138 and 51771089)+2 种基金the Guangdong Innovative and Entrepreneurial Research Team Program(2016ZT06G587)the Shenzhen Sci-Tech Fund(KYTDPT20181011104007)the Tencent Robotics X Lab Rhino-Bird Focused Research Program(JR201984)。
文摘Electronic skins and flexible pressure sensors are important devices for advanced healthcare and intelligent robotics.Sensitivity is a key parameter of flexible pressure sensors.Whereas introducing surface microstructures in a capacitive-type sensor can significantly improve its sensitivity,the signal becomes nonlinear and the pressure response range gets much narrower,significantly limiting the applications of flexible pressure sensors.Here,we designed a pressure sensor that utilizes a nanoscale iontronic interface of an ionic gel layer and a micropillared electrode,for highly linear capacitance-to-pressure response and high sensitivity over a wide pressure range.The micropillars undergo three stages of deformation upon loading:initial contact(0-6 k Pa)and structure buckling(6-12 k Pa)that exhibit a low and nonlinear response,as well as a post-buckling stage that has a high signal linearity with high sensitivity(33.16 k Pa-1)over a broad pressure range of 12-176 k Pa.The high linearity lies in the subtle balance between the structure compression and mechanical matching of the two materials at the gel-electrode interface.Our sensor has been applied in pulse detection,plantar pressure mapping,and grasp task of an artificial limb.This work provides a physical insight in achieving linear response through the design of appropriate microstructures and selection of materials with suitable modulus in flexible pressure sensors,which are potentially useful in intelligent robots and health monitoring.
