《医学三信编》论治中风病探讨

清代医家毛世洪在所撰《医学三信编》中对中风病的病因、病机及治疗方法进行了论述,他在继承前医家观点的基础上又有独创见解。梳理毛世洪对中风病的论治思想与方法,对中医临床治疗中风病具有借鉴意义。

医院图书馆创新与发展

在今天全新的信息环境之中,医院图书馆的信息资源、读者需求和图书馆应用技术发生极大的变化,医院图书馆正处在向网络化、数字化转型的时期。适应时代带给医院图书馆的变革,为适应读者对医学信息更高的需求,医院图书馆只有创新才能跟上时代的步伐进而在医学研究与临床领域中继续发挥重要作用。

A method based on mutual information and gradient information for medical image registration

Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual information and gradient information to solve this problem and apply it to the non-rigid deformation image registration. To improve the accuracy, we provide some implemental issues, for example, the Powell searching algorithm, gray interpolation and consideration of outlier points. The experimental results show the accuracy of the method and the feasibility in non-rigid medical image registration.

Investigations and thoughts of the ethics in genetic discrimination

A questionnaire research in ethics was conducted to get the view of students of medical universities in Shanghai on genomics and genetic discrimination. We find that 66% respondents indicated their willingness to understand the genetic information and 79% of respondents mind their own genetic information be aware of by other people. In contrast, 77% of the respondents believe that medical organization are not able to protect personal genetic information from disclose. Hence, it is significant to take some measures to preserve citizen's genetic information privacy. Depending on our results, we put forward our suggestion to this problem.

Science news release and its benefi ts to your research

News release to the latest science f indings is benef icial to both researchers and their served institutions as well as the public. It will help to set a bridge of communication between researchers, the public and media, and publishers, making the latest research findings well known to the public. World Journal of Gastroenterology has currently freely opened the News Release Service System (WJG-NRSS) for original articles with potential signifi cance and novelty for news release to mass media to broaden the f indings to the public.

Social practices of nurse care coordination using sensor technologies e Challenges with an alert system adoption in assisted living communities for older adults

Objectives:From the view of everyday practices and the socio-technical coordination lens,this study aimed to analyz the gap between creators’intention and the users’implementation(mainly nursing staff and social workers)of an alert system in assisted living communities.Methods:Qualitative methods were employed by way of five user interviews and focus groups with six system developers.Modeling instruments were applied for data collection to analyze the different clinical workflows versus the expectations of the system development team.Results:Results indicate that the clinical workflow changed over time,which led to a mismatch of nurse care coordination,social practices,and technology use.The results show different mental models of the socio-technical practice.Applying the coordination theory,the following recommendations could be developed to overcome the mismatch.First,it is recommended that nursing staff set goals together.Second,a communication rhythmwith the nursing staff and developer teams should be established,with guided questions to facilitate the conversation,to shed light on the different workflows and the difference in social practices when using sensor technologies or alert systems.Third,a checklist for new employees should be created so they know how and on which devices to use the alert system.Fourth,the user experience with the alert system should be improved(e.g.,an improved user interface).Conclusions:This work indicates recommendations to close the mental model gap to overcome the mismatch between optimal use of the alert system and how the nursing staff is actually using it.

Development of IT Triage System （TRACY） to Share Regional Disaster Medical Information

We developed an IT （Information Technology） triage system for collecting disaster medical information in real time. FeliCa cards and card readers are used to obtain the number and condition of patients. The system is composed of two elements. First, the number of patients for each triage level and the accepted number of patients in each diagnosis and treatment department are obtained in real time, including response for changing triage level. Second, this information is shared in real time among hospitals, the admim＇stration, and residents who are searching for their family. A disaster drill utilizing this system was held at the University of Yamanashi Hospital with 450 participants. From the result of that, the present system could work for those two elements. TRACY was examined its availability and practicability in this drill.

Performance of Spread Spectrum Watermarking in Autoregressive Host Model Under Additive White Gaussian Noise Channel

A large class of multimedia and biomedical signals can be modeled as Autotegessive （AR） random processes. Pefformance of watermarking embedding algorithms utilizing this host model is still left unexplored. The authors investigate the decoding perform-nance of Spread Spectrum （SS） embedding algorithm in the standard Additive White Gaussian Noise （AWGN） channel with the host signal being modeled as AR process. The SS embedding algorithm also use linear interference cancelation in the subspace spanned by watermark pattern. They study the influence of design parameters on the decoding performance. The analytic result is verified by Monte Carlo simulation on synthesized AR process. The result may be helpful to design watermarking system for speech, biomedical and image signals.

Online electrophysiological spike discrimination with wavelet-fractal signatures

Objective: To study extracellular multi-neuron activity in the nervous system based on wavelet-fractal technique. Methods: The wavelet transform was employed to decompose the original signal and obtain 4 sub-patterns. The dividing fractal dimensions of these sub-patterns were computed. A knn-classier was used to classify feature vectors. Results: Not all the elements in feature vector DimDC were very powerful for this pattern recognition problem through the empirical study of noise signals. The most effective feature vector was defined as DimDC= (d3:d4) above. Conclusion:Wavelet fractal algorithm has high accuracy and provides a powerful tool for clinical application.

An Improved Medical Image Fusion Algorithm for Anatomical and Functional Medical Images

In recent years,many medical image fusion methods had been exploited to derive useful information from multimodality medical image data,but,not an appropriate fusion algorithm for anatomical and functional medical images.In this paper,the traditional method of wavelet fusion is improved and a new fusion algorithm of anatomical and functional medical images,in which high-frequency and low-frequency coefficients are studied respectively.When choosing high-frequency coefficients,the global gradient of each sub-image is calculated to realize adaptive fusion,so that the fused image can reserve the functional information;while choosing the low coefficients is based on the analysis of the neighborbood region energy,so that the fused image can reserve the anatomical image's edge and texture feature.Experimental results and the quality evaluation parameters show that the improved fusion algorithm can enhance the edge and texture feature and retain the function information and anatomical information effectively.

Digital Chinese Medicine Research: an Overview

Digital Chinese medicine(DCM)is an emerging interdisciplinary field developed from traditional Chinese medicine(TCM)and information science.In this article,we consider the significance and propose an architecture for DCM research,and highlight the key tasks that need to be performed to provide references for the integration of information science into Chinese medicine research.

写给未来医学专家的信

未来医学界的专家：你们好!首先，我诚恳地请你们能在百忙之中读一读我写给你们的这封信。

Doctors' faith

We make some efforts to find some connections between religion and medical science. Medical science can be regarded as sacred and holy as a religion for doctors to believe. The common points between them are the basis to successfully integrate them into doctors' faith. Furthermore, we explain that doctors need a faith to believe so as to meet the demand of humanitarian traits we should have and to do better in the scientific work and win in the battles with the diseases.

The Reconstructing of Low Signal-noise Ratio Single Ion Channel Signal from Patch-clamp Recordings Sampled in the Colored Background Noise

The single ion channel signal is an ionic current that can be recorded by the patch clamp technique. Hidden Markov model (HMM) algorithm has been used to convert the low signal noise ratio (SNR) noisy recording into an idealized quantal one in the case of white background noise. The traditional HMM algorithm is extended and adapted to the colored background noise. A new algorithm called EHMM (Extended HMM) algorithm is proposed, and mainly validated by simulation. Results show that it’s effective.

The Multi-Disciplined Skills Required of Forensic Accountants

Forensic accountants today are required to possess a number of characteristics and skills that are derived from a range of disciplines. They must be inquisitive, able to delve into motivations, operations and justifications underlying the behavior of white collar criminals. They must be able to simplify technical accounting information and convey it effectively orally and in writing to a court or tribunal; be able to trace information via information technology tools; have an understanding of the adversarial legal system and the rules of evidence. Universities offering forensic accounting courses in various formats are on the increase. The aim of this paper is to investigate the subject areas that any course specializing in forensic accounting needs to cover.

Thoughts on Grade Teaching of ＂University Computer Basis＂ in Medical College

Along with information technology in depth, The combined degree of computer and medical specialty is more closely, students in computer operation level has greatly improved, traditional teaching in basic computer has been seriously impacted, ？This paper discusses the effect of the university Computer Basis reform in Medical College.

SVM for density estimation and application to medical image segmentation

A method of medical image segmentation based on support vector machine (SVM) for density estimation is presented. We used this estimator to construct a prior model of the image intensity and curvature profile of the structure from training images. When segmenting a novel image similar to the training images, the technique of narrow level set method is used. The higher dimensional surface evolution metric is defined by the prior model instead of by energy minimization function. This method offers several advantages. First, SVM for density estimation is consistent and its solution is sparse. Second, compared to the traditional level set methods, this method incorporates shape information on the object to be segmented into the segmentation process. Segmentation results are demonstrated on synthetic images, MR images and ultrasonic images.

A Miniaturized System for Neural Signal Acquiring and Processing

To collect neural activity data from awake, behaving freely animals, we develop miniaturized implantable recording system by the modem chip：Programmable System on Chip （PSoC） and through chronic electrodes in the cortex. With PSoC family member CY8C29466,the system completed operational and instrument amplifiers, filters, timers, AD convertors, and serial communication, etc. The signal processing was dealt with virtual instrument technology. All of these factors can significantly affect the price and development cycle of the project. The result showed that the system was able to record and analyze neural extrocellular discharge generated by neurons continuously for a week or more. This is very useful for the interdisciplinary research of neuroscience and information engineering technique. The circuits and architecture of the devices can be adapted for neurobiology and research with other small animals.

Continuation of cardiopulmonary resuscitation in a Chinese hospital after unsuccessful EMS resuscitation

Objective To evaluate the efficacy of the continuation of eardiopulmonary resuscitation （CPR） following transportation to the emergency department in a Chinese hospital after unsuccessful emergency medical services （EMS） CPR. Methods From January 2002 to December 2007, emergency records of non-traumatic patients who were transported to a tertiary teaching hospital after unsuccessful EMS CPR were reviewed. Results Eigty-five patients were included, and 13 patients （15%） accomplished restoration of spontaneous circulation in our emergency department. Resuscitative possibility reached zero at around 23 minutes. One patient was discharged with a favourable neurologic outcome. Conclusions This study shows that the continuation of CPR is not futile and may improve outcomes. The outcomes should be re-evaluated in the future when prehospital information can be combined with in-hospital information （J Geriatr Cardio12009; 6：142-146）.

Promotion of library management and book circulation to research on medical research

With the acceleration of the process of social information, information resources construction has become an important part of national development strategies. The library is one of the main information resources constructions and is an important information resource position of social construction. Computer applications in the book management, greatly improve the management efficiency of the library, and have changed the traditional management service model. Universal service network extends to every comer make reader can read everywhere, breaking the boundaries of time and space and also greatly promoting the modernization of the library. Library modernization, according to the characteristics of the objective law refers library work practices, uses modem technological conditions, rational organization of scientific management of library work, to maximize efficiency and quality and effectively complete the task library. Library essence of modem management techniques is to achieve the modernization of libraries and library management modernization. Modem library information system can be divided into three aspects of building automation libraries, library networks and digital libraries. Digital library management directly reflects a country＇ s level of a regional knowledge economy and information industry development, and digital network resource management in the book gradually dominates.