现代有机分析化学在食品分析及医药学分析中的应用

在科学研究不断深入发展过程中,现代有机分析化学也得到了迅猛发展,并衍生出多种新仪器、新理论以及新方法,有力的保障着人们的生存、生产。为了更加充分的发挥现代有机分析化学的优势和作用,本文分别研究现代有机分析化学在食品分析中和医药学分析中的具体应用,促进现代有机分析化学相关研究更加深入、准确、微量和灵敏。

荧光光纤传感器在医药学中的应用研究

荧光光纤化学传感器因其敏感、特异及可远程、在位、连续检测等优点 ,已在医学、药学、化学反应监测等方面得到了较广泛应用。本文主要就荧光光纤传感器在医药学分析方面的应用研究进行综述。

杨贵妃“雪肤花貌”的秘诀

杨贵妃“雪肤花貌”的秘诀文／乔富渠号称“天下第一汤”的华清池温泉，位于西安市以东３０公里的临潼县骊山北麓，这里山清水秀，风光旖旎，松柏碧翠，温泉潺潺，是历代帝王后妃游乐之地。相传早在两千七百多年前的西周时期，周幽王就在此修建露天浴池“星辰汤”。秦始皇...

Visual analysis of research hotspots and trends in the treatment of immune thrombocytopenia with traditional Chinese medicine

Objective Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine(TCM)treatment of immune thrombocytopenia(ITP),this study aims to sort out the overall research progress,hotspots,and trends in this field,and provide reference for further research in ITP.Methods The articles on ITP treated by TCM were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Database,China Science and Technology Journal Database(VIP),Web of Science Core Collection(WOSCC),and PubMed.The retrieval time was from the establishment of the databases to July 31,2022.VOSviewer,CiteSpace,Carrot2,and Note-Express were used for data analysis of the articles in terms of their quantities,types,and journals,and for visualization of research hotspots,authors,institutions,and keywords.Results 1493 Chinese articles and 40 English articles were included.The articles in Chinese mainly focus on clinical trial research and clinical experience summary,while the English articles mainly focus on clinical trial research and animal research.The Chinese articles were published in 317 Chinese journals,while English articles were published in 29 English journals.Research hotspots include the clinical syndrome differentiation of ITP,the therapeutic effect of TCM compounds on ITP,and the mechanism of ITP treatment.Keyword analysis shows that there are many research achievements in integrated traditional Chinese and western medicine treatment,clinical research,famous doctors’experience,TCM treatment,cellular immunity,and humoral immunity.The authors with the most articles in Chinese and English are Professor CHEN Xinyi and Professor MA Rou,respectively,and the research institutions with the most articles are Dongzhimen Hospital of Beijing University of Chinese Medicine and Xiyuan Hospital of China Academy of Chinese Medical Sciences.Chinese herbs often used to treat ITP clinically include Xianhecao(Agrimoniae Herba),Nvzhenzi(Ligustri Lucidi Fructus),Mohanlian(Ecliptae Herba),Zhongjiefeng(Sarcandrae Herba),etc.,and the prescription usually used to treat ITP include Guipi Decoction(归脾汤),Xijiao Dihuang Decoction(犀角地黄汤),Bazhen Decoction(八珍汤),Erzhi Pill(二至丸),and Xiaochaihu De-coction(小柴胡汤).The main development trends toward retrospective study,TCM treatment mechanism,and data mining.

Correlation Analysis between TCM Syndromes and Physicochemical Parameters

Traditionally, differentiation of syndromes of Traditional Chinese Medicine (TCM) mainly depends on the information obtained from four diagnosis methods. Now many physicochemical parameters are available in clinic. There exists great correlation between TCM syndromes and physicochemical parameters. The objective of the paper is to analyze the correlation between TCM syndromes and physicochemical parameters quantitatively. Correlation analysis has been widely studied and many analysis methods have been developed. Mutual information based on entropy can measure arbitrary dependence between variables. It has been applied to many kinds of fields, especially to pattern recognition. But most works are restricted to discrete variables and little work has been done to study the relation between discrete and continuous variables. A novel algorithm is proposed to calculate the mutual information between discrete and continuous variables. It is used to analyze the correlation between TCM syndromes and physicochemical parameters.

From the Perspective of Chinese Medicine Sales Analysis on Development Situation of Traditional Chinese Medicine Industry in Guangxi

After years of development, has emerged a group of outstanding enterprises in Guangxi, creating a high popularity and good reputation of the product. But from 2013 data can be seen in the study of traditional Chinese medicine industry of China, Guangxi traditional Chinese medicine products in the market space is still limited in the province, the market share of the market at a relatively low level in the country. This is from a macro-perspective analysis of the national sales on traditional Chinese medicine of Guangxi Chinese medicine industry development in present situation and makes problem-oriented industrial policy advice to counter.

Applications of aptamers for chemistry analysis, medicine and food security

Since aptamer and its in vitro selection process called SELEX were independently described by Ellington and Gold in 1990, extensive research has been undertaken and numerous isolated aptamers for various targets have been applied. Aptamers can bind to a wide range of targets that include small organic molecules, inorganic compounds, haptens and even whole cells with high binding affinity and specificity. Aptamers for a wide range of targets have been selected currently. In addition, aptamers are thermo stable and can also be regenerated easily within a few minutes denaturation, which makes them easy to store or handle. These advantages make aptamers extremely suitable for applications based on molecular recognition as analytical, diagnostic and therapeutic tools. In this review, the recent applications of aptamers for chemistry analysis, medicine and food security, along with the future trend will be discussed.

Road traffic deaths in Kashan region, Iran： An eight-year study （2006-2013）

Purpose： The aim of this study was to analyze the trend of road traffic fatalities in Kashan Region, lran, in a period of eight years. Methods： Through a cross-sectional study, all road traffic deaths classified under the VO1-V99 codes according to ICD-10 in Kashan region, central Iran, from March 2006 to March 2013 and population data were collected from the registration system of Kashan University of Medical Sciences. Years of lost life （YLL） and mortality rates were calculated regarding age, gender and year of the accident. Generalized linear model （GLM） with Poisson log-linear link was used to evaluate the effects of the mentioned variables on mortality rate. Results： During the period of the study （8 years）, 928 people （767 men） died due to road traffic injuries （RTIs）. The total YLL was 20,818. The mortality rate due to RTIs has been declined constantly from 43.1 in March 2006 to 21.1 per 100,000 in March 2013. The highest mortality rate was found in the age group of over 60 years old and the lowest in the age group of 0-14 years old. Both mortality rate and YLL was greater in men than in women. Poisson regression showed that age, gender and year of the accidents had a significant effect on mortality rate （p 〈 0.001 ）. Conclusion： Although there has been a constant decline of mortality rate in Kashan area within the study period, the value remains higher than the mean level of Eastern Mediterranean region and the global average, which is a notable fact for policymakers and authorities.