The development of fracture around pre-existing cylindrical cavities in brittle rocks was examined using physical models and acoustic emission technique. The experimental results indicate that when granite blocks cont...The development of fracture around pre-existing cylindrical cavities in brittle rocks was examined using physical models and acoustic emission technique. The experimental results indicate that when granite blocks containing one pre-existing cylindrical cavity are loaded in uniaxial compression condition, the profiles of cracks around the cavity can be characterized by tensile cracking (splitting parallel to the axial compression direction) at the roof-floor, compressive crack at two side walls, and remote or secondary cracks at the perimeter of the cavity. Moreover, fracture around cavity is size-dependent. In granite blocks containing pre-existing half-length cylindrical cavities, compressive stress concentration is found to initiate at the two sidewalls and induce shear crack propagation and coalescence. In granite blocks containing multiple parallel cylindrical cavities, the adjacent cylindrical cavities can influence each other and the eventual failure mode is determined by the interaction of tensile, compressive and shear stresses. Experimental results show that both tensile and compressive stresses play an important role in fracture evolution process around cavities in brittle rocks.展开更多
Ontogeny and metamorphic. development of female reproductive organs in Ephedra sinica Stapf were surveyed. At the end of April, female cones began to initialize from the vegetative buds. Pollination occurred in mid-Ma...Ontogeny and metamorphic. development of female reproductive organs in Ephedra sinica Stapf were surveyed. At the end of April, female cones began to initialize from the vegetative buds. Pollination occurred in mid-May and seeds matured at the beginning of July. The ontogenetic pattern of female reproductive organs of E. sin ca is basically similar to that of E. distachya L. The foliar nature of the outer envelope of the ovule in Ephedra is corroborated. Reduction of ovule number as a tendency of speciation in the genus is substantiated by the occurrence of tri-ovulate cones coupled with comprehensive characters of the genus. The metamorphic patterns as well as the leaf nature of the outer envelope indicate that female cones of Ephedra are compound while the female reproductive units of the ovulate cone have been reduced from secondary reproductive shoots similar to those of cordaites by phylogenetic transformation, fusion and reduction. Each fertile bract together with its axillary female reproductive unit composed the Bract Scale and Seed Scale Complex of Ephedra.展开更多
Terrain texture analysis is an important method of digital terrain analysis in quantitative geomorphological research and in the exploration of the spatial heterogeneity and autocorrelation of terrain features. Howeve...Terrain texture analysis is an important method of digital terrain analysis in quantitative geomorphological research and in the exploration of the spatial heterogeneity and autocorrelation of terrain features. However, a major issue often neglected in previous studies is the calculation unit of the terrain texture, that is, the stability analysis unit. As the test size increases, the derived terrain textures become increasingly similar so that their differences can be ignored. The test size of terrain texture is defined as the stability analysis unit. This study randomly selected 48 areas within the Loess Plateau in northern Shaanxi in China as the study sites and used the gray level co-occurrence matrix to calculate the terrain texture. The stability analysis unit of the terrain texture was then extracted, and its spatial distribution pattern in the Loess Plateau was studiedusing spatial interpolation method. Four terrain texture metrics, i.e., homogeneity, energy, correlation, and contrast, were extracted on the basis of the stability analysis unit, and the spatial variation patterns of these parameters were studied. Results showed that the spatial distribution pattern and the terrain texture metrics reflected a trend of high–low–high from north to south, which correlated with the spatial distribution of the landforms at the Loess Plateau. In addition, the terrain texture measures was significantly correlated with the terrain factors of gully density and slope, and this relationship showed that terrain texture measures based on the stability analysis unit could reflect the basic characteristics of terrain morphology. The stability analysis unit provided a reasonable analytical scale for terrain texture analysis and could be used as a measure of the regional topography to accurately describe basic terrain characteristics.展开更多
Field investigations and aerial photography after the earthquake of May 12, 2008 show a large number of geo-hazards in the zone of extreme earthquake effects. In particular, landslides and debris flows, the geo-ha...Field investigations and aerial photography after the earthquake of May 12, 2008 show a large number of geo-hazards in the zone of extreme earthquake effects. In particular, landslides and debris flows, the geo-hazards that most threaten post-disaster reconstruction, are widely distributed. We describe the characteristics of these geo-hazards in Beichuan County using high-resolution remote sensing of landslide distribution, and the relationships between the area and volume of landslides and the peak-discharges of debris flows both pre- and post-earthquake. The results show: 1) The concentration (defined as the number of landslide sources per unit area: Lc) of earthquake- triggered landslides is inversely correlated with distance from the earthquake (DF) fault. The relationship is described by the following equation: Lc = 3.2264exp(-0.0831DF) (R2 = 0.9246); 2) 87 % of the earthquake-triggered landslides were less than 15× 10^4 m2 in area, and these accounted only for 5o% of the total area; 84% of the landslide volumes were less than 60×10^4 m3, and these accounted only for 50% of the total volume. The probability densities of the area and volume distributions are correlated: landslide abundance increases with landslide area and volume up to maximum values of 5 ×10^4m2 and 30 ×10^4 m3, respectively, and then decreases exponentially. 3) The area (AL) and volume (VL) of earthquake-triggered landslides are correlated as described with the following equation: VL=6.5138AL1.0227 (R2 = 0.9231); 4)Characteristics of the debris flows changed after the earthquake because of the large amount of landslide material deposited in the gullies. Consequently, debris flow peak-discharge increased following the earthquake as described with the following equation: Vpost = 0.8421Vprel-0972 (R2 = 0.9821) (Vpre is the peak discharge ofpre-earthquake flows and the Vpost is the peak discharge of post-earthquake flows). We obtained the distribution of the landslides based on the above analyses, as well as the magnitude of both the landslides and the post-earthquake debris flows. The results can be useful for guiding post-disaster reconstruction and recovery efforts, and for the future mitigation of these geo-hazards. However, the equations presented are not recommended for use in site-specific designs. Rather, we recommend their use for mapping regional seismic landslide hazards or for the preliminary, rapid screening of sites.展开更多
Background Disturbed circadian rhythm is a potential cause of delirium and is linked to disorganisation of the circadian rhythmicity. Dynamic light (DL) could reset the circadian rhythm by activation of the suprachi...Background Disturbed circadian rhythm is a potential cause of delirium and is linked to disorganisation of the circadian rhythmicity. Dynamic light (DL) could reset the circadian rhythm by activation of the suprachiasmatic nucleus to prevent delirium. Evidence regarding the effects of light therapy is predominantly focused on psychiatric disorders and circadian rhythm sleep disorders. In this study, we investi- gated the effect of DL on the total hospital length of stay (LOS) and occurrence of delirium in patients admitted to the Coronary Care Unit (CCU). Methods This was a retrospective cohort study. Patients older than 18 years, who were hospitalized longer than 12 h at the CCU and had a total hospital LOS for at least 24 h, were included. Patients were assigned to a room with DL (n = 369) or regular lighting condi- tions (n = 379). DL was administered at the CCU by two ceiling-mounted light panels delivering light with a colour temperature between 2700 and 6500 degrees Kelvin. Reported outcome data were: total hospital LOS, delirium incidence, consultation of a geriatrician and the amount of prescripted antipsychotics. Results Between May 2015 and May 2016, data from 748 patients were collected. Baseline charac- teristics, including risk factors provoking delirium, were equal in both groups. Median total hospital LOS in the DL group was 100.5 (70.8-186.0) and 101.0 (73.0-176.4) h in the control group (P = 0.935). The incidence of delirium in the DL and control group was 5.4% (20/369) and 5.0% (19/379), respectively (P = 0.802). No significant differences between the DL and control group were observed in secon- dary endpoints. Subgroup analysis based on age and CCU LOS also showed no differences. Conclusion Our study suggests exposure to DL as an early single approach does not result in a reduction of total hospital LOS or reduced incidence of delirium. When delirium was diagnosed, it was associated with poor hospital outcome.展开更多
With the rapid development of economy,the conversion of cultivated land into nonagricultural land occurs more frequently and makes cultivated land sparser.This article based on the decoupling theory takes the situatio...With the rapid development of economy,the conversion of cultivated land into nonagricultural land occurs more frequently and makes cultivated land sparser.This article based on the decoupling theory takes the situations of cultivated land occupation by construction and economic growth in China from 1998 to 2007 as an example to evaluate and analyze the decoupling.The conclusions are drawn as follows.First,the article applies IU curve and gross method.The decoupling status by gross method,in contrast to that by IU curve,can express the pressure from cultivated land occupation better and is similar to the decoupling status based on the model of decoupling in this article.Second,in most provinces of China,the relationship between the cultivated land occupation by construction and economic growth has transformed from expansive negative decoupling to strong decoupling.In general,the transformation was firstly from economically advanced eastern municipalities under the central government directly,then to economically advanced eastern coastal provinces,and lastly to central,western and northeastern regions.Third,the decoupling status was relative to contemporaneous policies and laws on cultivated land protection and regional development planning.Their effect is obvious and positive.展开更多
In the software engineering literature, it is commonly believed that economies of scale do not occur in case of software Development and Enhancement Projects (D&EP). Their per-unit cost does not decrease but increa...In the software engineering literature, it is commonly believed that economies of scale do not occur in case of software Development and Enhancement Projects (D&EP). Their per-unit cost does not decrease but increase with the growth of such projects product size. Thus this is diseconomies of scale that occur in them. The significance of this phenomenon results from the fact that it is commonly considered to be one of the fundamental objective causes of their low effectiveness. This is of particular significance with regard to Business Software Systems (BSS) D&EP characterized by exceptionally low effectiveness comparing to other software D&EP. Thus the paper aims at answering the following two questions: (1) Do economies of scale really not occur in BSS D&EP? (2) If economies of scale may occur in BSS D&EP, what factors are then promoting them? These issues classify into economics problems of software engineering research and practice.展开更多
Two soluble copolymers of fluorenone and dioctoxylbenzene (PFN) or anthracene (PFNAn) were synthesized through Heck polymerization, and were characterized by gel permeation chromatography (GPC), FT-IR, IH-NMR, e...Two soluble copolymers of fluorenone and dioctoxylbenzene (PFN) or anthracene (PFNAn) were synthesized through Heck polymerization, and were characterized by gel permeation chromatography (GPC), FT-IR, IH-NMR, elemental analysis and thermogravimetric analysis. The polymers possess good solubility in common organic solvents and high thermal stability with the Onset decomposition temperature at higher than 410 ℃. The photophysical properties of the polymers were investigated in both solutions and spin-coated films. Cyclic voltammetry results revealed that the copolymers possess higher electron affinity and reversible reduction/re-oxidation processes. Their electroluminescent properties were further investigated. PFN and PFNAn show stable and saturated red light emission with high thermal stability and high electron injection ability. This type of conjugated polymers may be promising for the applications as electron acceptors in polymer photovoltaic cells and electron transporting materials.展开更多
This serial research develops the unique ocean wave power station, which is composed of the floating type platform with a pair of the floats arranged at the interval of one wavelength and the counter-rotating type wav...This serial research develops the unique ocean wave power station, which is composed of the floating type platform with a pair of the floats arranged at the interval of one wavelength and the counter-rotating type wave power unit whose runners are submerged in the seawater at the middle position of the platform. Such profiles make the flow velocity through the runners two times faster than that of the traditional fixed/caisson type OWC (oscillating water column), that is, the runners may be able to get the dynamical energy eight times on the ideal. Besides, the runners counter-drive the inner and the outer armatures of the peculiar generator, respectively, and then the relative rotational speed is two times as fast as the speed of the single runner/armature. Such characteristics make the runner diameter large, namely the output higher, as you request, because the rotational moment of the power unit hardly act on the floating type platform. This paper, as the first step, discusses the platform behaviors at the normally oscillating wave. The platform behavior is affected by not only the length and the amplitude of the wave but also the relation between the weight of the platform and the buoyancy force of the floats.展开更多
Medicines are a global, strategic and diplomatic issue [1]. The UN General Secretary’s High Level Task Force [2] on Access to Medicines calls for a new approach to reduce the gap between medical innovations and acces...Medicines are a global, strategic and diplomatic issue [1]. The UN General Secretary’s High Level Task Force [2] on Access to Medicines calls for a new approach to reduce the gap between medical innovations and access to medicines. Inequality in access to quality pharmaceutical products in a framework of global health democracy poses a threat to the ethical and equitable management of the provision of quality health care, particularly during global health crises. In French-speaking Africa, the lack of a unified production of pharmaceutical medicines forces wholesalers (public and private) to import almost all of their medicine demands resulting in a risk of dependence and major pharmaceutical quality defects. These central purchasing units are therefore often faced with the major challenge of guaranteeing the performance of their services and the security of their supplies. In order to achieve component 3 (“Access to Health”) of the SDOs (sustainable development goals), in particular the access to affordable medicines, it is essential for a country to have a strategy of pharmaceutical independence [3] by anticipating the epidemiological transition and the management of health crises. This strategy of pharmaceutical independence is based in the short and medium term on the strengthening of central purchasing units and the establishment of a public-private partnership between central purchasing units and wholesalers, and in the long term on the establishment of competitive production units that comply with international standards. However, recent health crises have shown the fragility of public central purchasing units and make it difficult to anticipate health crises.展开更多
In the reform of government organizations and institutions of China, we put forward the establishment of personal account system in occupational pension, and the introduction of the "account" management model of the...In the reform of government organizations and institutions of China, we put forward the establishment of personal account system in occupational pension, and the introduction of the "account" management model of the non real account accumulation. This paper analyzes the current situation of personal accounts in our country, and puts forward that the account rate of bank deposit can not resist inflation, and can not reflect the real return rate of China's pension funds, which is not conducive to the preservation and appreciation of personal account funds. On the basis of the above, the paper puts forward that the account rate should not only consider the level of economic development and inflation, but also to adapt to the financial payment ability, and establish the personal account risk reserve fund system and other improvement measures, and strive to achieve the sustainable development of the personal account system.展开更多
In the new century, quantum technology has developed rapidly and has been applied in many fields. As an important aspect of the aerospace science, metrology and measuring science is a field which is influenced by the ...In the new century, quantum technology has developed rapidly and has been applied in many fields. As an important aspect of the aerospace science, metrology and measuring science is a field which is influenced by the quantum technology dramatically. The new generation of the International System of Units will be redefined on the basis of the quantum theory. More and more new sensing techniques are developed taking into account quantum principles. In this paper, the influence of quantum technology on metrology and measuring science is introduced.展开更多
The extensive research on public ethics in the local administration is more than necessary. This paper identifies the basic values of and the challenges to Macedonian Legal System in this area, and explains the key et...The extensive research on public ethics in the local administration is more than necessary. This paper identifies the basic values of and the challenges to Macedonian Legal System in this area, and explains the key ethical aspects, which should be implemented in practice by civil servants, who increasingly have to learn how to perform in accordance with ethical values. In this paper I will analyze the ethical values of civil servants laid down by the Organization for Economic Co-operation and Development (OECD) and the Civil Servants Agency in Macedonia, upon which the ethical principles for civil servants in the local administration units are intended to be set. This paper deals with the ethics of civil servants, assessment of best practices, and evaluation of positive and negative indicators. The paper concludes with a few recommendations for the next steps in this process; and some criteria for the consideration of future developments are suggested.展开更多
To investigate diagnostic accuracy of 2-hour protocol of rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion SPECT in chronic coronary artery disease. Sixty-seven patients with suspecte...To investigate diagnostic accuracy of 2-hour protocol of rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion SPECT in chronic coronary artery disease. Sixty-seven patients with suspected CAD were enrolled in the prospective study. All patients underwent myocardial perfusion scintigraphy in SPECT with dual isotopes of T1-201 and dipyridamole stress Tc-99m sestamibi. Rest and stress imaging protocol were performed in 2 hours by dose of 3 mCi TI-201 and 25 mCi Tc-99m sestamibi. The acquisition parameters includes LEHR collimator, energy peak of 72 and 167 keV for T1-201 and 140 keV for Tc-99m, 180-degree rotation from RAO to LPO, matrix size 64x64, and 25second/frame/64 frames. The 20-segment model of left ventricle was used in automatic quantitation software. Coronary angiography was used as gold standard. CAD was defined as 50% of lumen stenosis on coronary angiography. Rest TI-201/stress tc-99m sestamibi dual-isotope SPECT demonstrated a sensitivity of 94.59% and specificity of 70%, positive predictive value of 79.54% and negative predictive value of 91.3% in detection of coronary artery disease. Sensitivity and specificity for detecting multi-vessel coronary artery disease were 82.75% and 81.57% for the left anterior descending, 77.77% and 91.83% for left circumflex and 94.11% and 82% for right coronary artery. 2-hour protocol of rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion SPECT has high sensitivity, specificity, positive predictive value and negative predictive value in detecting chronic coronary artery disease with greater than 50% stenosis assessed by coronary angiography Moreover, this imaging protocol gives high imaging quality, time-saving and convenience.展开更多
A 300 μm×300 μm light emitting diode(LED) chip is divided into nine 80 μm×80 μm units with 30 μm spacing between adjacent ones. After arraying, the total saturation light output power and the maximum in...A 300 μm×300 μm light emitting diode(LED) chip is divided into nine 80 μm×80 μm units with 30 μm spacing between adjacent ones. After arraying, the total saturation light output power and the maximum injection current are enhanced by 5.19 times and nearly 7 times, respectively. In addition, the test results demonstrate that the illuminance uniformity on the receiving surface reaches the optimum when the spacing between the arrays is equal to the maximum flat condition. The larger the number of arrays, the greater the area with uniform illuminance on the receiving surface.展开更多
Tetraphenylethene (TPE) is a popular luminogen characterized by aggregation-induced emission and has been widely used to construct solid-state emissive materials. In this work, two thermally stable polymers (P1 and P2...Tetraphenylethene (TPE) is a popular luminogen characterized by aggregation-induced emission and has been widely used to construct solid-state emissive materials. In this work, two thermally stable polymers (P1 and P2) consisting of TPE conjugated to the 2,7-positions of fluorene and carbazole, respectively, are synthesized and characterized. Both polymers are weakly fluorescent in solutions but show greatly enhanced emission as the aggregate formation, presenting an aggregation-enhanced emission feature. Two kinds of polymer light-emitting diodes are fabricated utilizing P1 and P2 as emitters (EML) (device I: ITO/PEDOT:PSS (45 nm)/PVK:EML (1:1 wt%, 55 nm)/TPBI (38 nm)/Ca:Ag; device II: ITO/PEDOT:PSS (45 nm)/ PVK:OXD-7:EML (3:1:3 wt%, 55 nm)/TPBI (38 nm)/Ca:Ag). The device II of P2 shows the best performances, affording a maximum luminance of 6500 cd/m 2 and a high peak efficiency of 2.11 cd/A.展开更多
基金Projects(51004025,51174044)supported by the National Natural Science Foundation of ChinaProject(2011AA060400)supported by the National High-tech Research and Development Program of China+1 种基金Project(N120501003)supported by Ministry of Education of the People’s Republic of ChinaProject(LJQ2012024)supported by Department of Education of Liaoning Province,China
文摘The development of fracture around pre-existing cylindrical cavities in brittle rocks was examined using physical models and acoustic emission technique. The experimental results indicate that when granite blocks containing one pre-existing cylindrical cavity are loaded in uniaxial compression condition, the profiles of cracks around the cavity can be characterized by tensile cracking (splitting parallel to the axial compression direction) at the roof-floor, compressive crack at two side walls, and remote or secondary cracks at the perimeter of the cavity. Moreover, fracture around cavity is size-dependent. In granite blocks containing pre-existing half-length cylindrical cavities, compressive stress concentration is found to initiate at the two sidewalls and induce shear crack propagation and coalescence. In granite blocks containing multiple parallel cylindrical cavities, the adjacent cylindrical cavities can influence each other and the eventual failure mode is determined by the interaction of tensile, compressive and shear stresses. Experimental results show that both tensile and compressive stresses play an important role in fracture evolution process around cavities in brittle rocks.
文摘Ontogeny and metamorphic. development of female reproductive organs in Ephedra sinica Stapf were surveyed. At the end of April, female cones began to initialize from the vegetative buds. Pollination occurred in mid-May and seeds matured at the beginning of July. The ontogenetic pattern of female reproductive organs of E. sin ca is basically similar to that of E. distachya L. The foliar nature of the outer envelope of the ovule in Ephedra is corroborated. Reduction of ovule number as a tendency of speciation in the genus is substantiated by the occurrence of tri-ovulate cones coupled with comprehensive characters of the genus. The metamorphic patterns as well as the leaf nature of the outer envelope indicate that female cones of Ephedra are compound while the female reproductive units of the ovulate cone have been reduced from secondary reproductive shoots similar to those of cordaites by phylogenetic transformation, fusion and reduction. Each fertile bract together with its axillary female reproductive unit composed the Bract Scale and Seed Scale Complex of Ephedra.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41471316, 41571383, 41671389)the Priority Academic Program Development of Jiangsu Higher Education Institutions-PAPD (Grant No. 164320H101)the Key Project of Natural Science Research of Anhui Provincial Department of Education (Grant No. KJ2015A171)
文摘Terrain texture analysis is an important method of digital terrain analysis in quantitative geomorphological research and in the exploration of the spatial heterogeneity and autocorrelation of terrain features. However, a major issue often neglected in previous studies is the calculation unit of the terrain texture, that is, the stability analysis unit. As the test size increases, the derived terrain textures become increasingly similar so that their differences can be ignored. The test size of terrain texture is defined as the stability analysis unit. This study randomly selected 48 areas within the Loess Plateau in northern Shaanxi in China as the study sites and used the gray level co-occurrence matrix to calculate the terrain texture. The stability analysis unit of the terrain texture was then extracted, and its spatial distribution pattern in the Loess Plateau was studiedusing spatial interpolation method. Four terrain texture metrics, i.e., homogeneity, energy, correlation, and contrast, were extracted on the basis of the stability analysis unit, and the spatial variation patterns of these parameters were studied. Results showed that the spatial distribution pattern and the terrain texture metrics reflected a trend of high–low–high from north to south, which correlated with the spatial distribution of the landforms at the Loess Plateau. In addition, the terrain texture measures was significantly correlated with the terrain factors of gully density and slope, and this relationship showed that terrain texture measures based on the stability analysis unit could reflect the basic characteristics of terrain morphology. The stability analysis unit provided a reasonable analytical scale for terrain texture analysis and could be used as a measure of the regional topography to accurately describe basic terrain characteristics.
基金supported by the National Key Fundamental Research Program of China (973) (2008CB425802)The Project Group of Knowledge Innovation Program of Chinese Academy Sciences (KZCX2-YW-Q03-5)
文摘Field investigations and aerial photography after the earthquake of May 12, 2008 show a large number of geo-hazards in the zone of extreme earthquake effects. In particular, landslides and debris flows, the geo-hazards that most threaten post-disaster reconstruction, are widely distributed. We describe the characteristics of these geo-hazards in Beichuan County using high-resolution remote sensing of landslide distribution, and the relationships between the area and volume of landslides and the peak-discharges of debris flows both pre- and post-earthquake. The results show: 1) The concentration (defined as the number of landslide sources per unit area: Lc) of earthquake- triggered landslides is inversely correlated with distance from the earthquake (DF) fault. The relationship is described by the following equation: Lc = 3.2264exp(-0.0831DF) (R2 = 0.9246); 2) 87 % of the earthquake-triggered landslides were less than 15× 10^4 m2 in area, and these accounted only for 5o% of the total area; 84% of the landslide volumes were less than 60×10^4 m3, and these accounted only for 50% of the total volume. The probability densities of the area and volume distributions are correlated: landslide abundance increases with landslide area and volume up to maximum values of 5 ×10^4m2 and 30 ×10^4 m3, respectively, and then decreases exponentially. 3) The area (AL) and volume (VL) of earthquake-triggered landslides are correlated as described with the following equation: VL=6.5138AL1.0227 (R2 = 0.9231); 4)Characteristics of the debris flows changed after the earthquake because of the large amount of landslide material deposited in the gullies. Consequently, debris flow peak-discharge increased following the earthquake as described with the following equation: Vpost = 0.8421Vprel-0972 (R2 = 0.9821) (Vpre is the peak discharge ofpre-earthquake flows and the Vpost is the peak discharge of post-earthquake flows). We obtained the distribution of the landslides based on the above analyses, as well as the magnitude of both the landslides and the post-earthquake debris flows. The results can be useful for guiding post-disaster reconstruction and recovery efforts, and for the future mitigation of these geo-hazards. However, the equations presented are not recommended for use in site-specific designs. Rather, we recommend their use for mapping regional seismic landslide hazards or for the preliminary, rapid screening of sites.
文摘Background Disturbed circadian rhythm is a potential cause of delirium and is linked to disorganisation of the circadian rhythmicity. Dynamic light (DL) could reset the circadian rhythm by activation of the suprachiasmatic nucleus to prevent delirium. Evidence regarding the effects of light therapy is predominantly focused on psychiatric disorders and circadian rhythm sleep disorders. In this study, we investi- gated the effect of DL on the total hospital length of stay (LOS) and occurrence of delirium in patients admitted to the Coronary Care Unit (CCU). Methods This was a retrospective cohort study. Patients older than 18 years, who were hospitalized longer than 12 h at the CCU and had a total hospital LOS for at least 24 h, were included. Patients were assigned to a room with DL (n = 369) or regular lighting condi- tions (n = 379). DL was administered at the CCU by two ceiling-mounted light panels delivering light with a colour temperature between 2700 and 6500 degrees Kelvin. Reported outcome data were: total hospital LOS, delirium incidence, consultation of a geriatrician and the amount of prescripted antipsychotics. Results Between May 2015 and May 2016, data from 748 patients were collected. Baseline charac- teristics, including risk factors provoking delirium, were equal in both groups. Median total hospital LOS in the DL group was 100.5 (70.8-186.0) and 101.0 (73.0-176.4) h in the control group (P = 0.935). The incidence of delirium in the DL and control group was 5.4% (20/369) and 5.0% (19/379), respectively (P = 0.802). No significant differences between the DL and control group were observed in secon- dary endpoints. Subgroup analysis based on age and CCU LOS also showed no differences. Conclusion Our study suggests exposure to DL as an early single approach does not result in a reduction of total hospital LOS or reduced incidence of delirium. When delirium was diagnosed, it was associated with poor hospital outcome.
基金supported by the National Natural Science Foundation of China (Grant no.70673097)
文摘With the rapid development of economy,the conversion of cultivated land into nonagricultural land occurs more frequently and makes cultivated land sparser.This article based on the decoupling theory takes the situations of cultivated land occupation by construction and economic growth in China from 1998 to 2007 as an example to evaluate and analyze the decoupling.The conclusions are drawn as follows.First,the article applies IU curve and gross method.The decoupling status by gross method,in contrast to that by IU curve,can express the pressure from cultivated land occupation better and is similar to the decoupling status based on the model of decoupling in this article.Second,in most provinces of China,the relationship between the cultivated land occupation by construction and economic growth has transformed from expansive negative decoupling to strong decoupling.In general,the transformation was firstly from economically advanced eastern municipalities under the central government directly,then to economically advanced eastern coastal provinces,and lastly to central,western and northeastern regions.Third,the decoupling status was relative to contemporaneous policies and laws on cultivated land protection and regional development planning.Their effect is obvious and positive.
文摘In the software engineering literature, it is commonly believed that economies of scale do not occur in case of software Development and Enhancement Projects (D&EP). Their per-unit cost does not decrease but increase with the growth of such projects product size. Thus this is diseconomies of scale that occur in them. The significance of this phenomenon results from the fact that it is commonly considered to be one of the fundamental objective causes of their low effectiveness. This is of particular significance with regard to Business Software Systems (BSS) D&EP characterized by exceptionally low effectiveness comparing to other software D&EP. Thus the paper aims at answering the following two questions: (1) Do economies of scale really not occur in BSS D&EP? (2) If economies of scale may occur in BSS D&EP, what factors are then promoting them? These issues classify into economics problems of software engineering research and practice.
基金Projects(50803074, 50633050) supported by the National Natural Science Foundation of ChinaProject supported by the Opening Fund of State Key Laboratory of Powder MetallurgyStart-up Fund of Central South University, China
文摘Two soluble copolymers of fluorenone and dioctoxylbenzene (PFN) or anthracene (PFNAn) were synthesized through Heck polymerization, and were characterized by gel permeation chromatography (GPC), FT-IR, IH-NMR, elemental analysis and thermogravimetric analysis. The polymers possess good solubility in common organic solvents and high thermal stability with the Onset decomposition temperature at higher than 410 ℃. The photophysical properties of the polymers were investigated in both solutions and spin-coated films. Cyclic voltammetry results revealed that the copolymers possess higher electron affinity and reversible reduction/re-oxidation processes. Their electroluminescent properties were further investigated. PFN and PFNAn show stable and saturated red light emission with high thermal stability and high electron injection ability. This type of conjugated polymers may be promising for the applications as electron acceptors in polymer photovoltaic cells and electron transporting materials.
文摘This serial research develops the unique ocean wave power station, which is composed of the floating type platform with a pair of the floats arranged at the interval of one wavelength and the counter-rotating type wave power unit whose runners are submerged in the seawater at the middle position of the platform. Such profiles make the flow velocity through the runners two times faster than that of the traditional fixed/caisson type OWC (oscillating water column), that is, the runners may be able to get the dynamical energy eight times on the ideal. Besides, the runners counter-drive the inner and the outer armatures of the peculiar generator, respectively, and then the relative rotational speed is two times as fast as the speed of the single runner/armature. Such characteristics make the runner diameter large, namely the output higher, as you request, because the rotational moment of the power unit hardly act on the floating type platform. This paper, as the first step, discusses the platform behaviors at the normally oscillating wave. The platform behavior is affected by not only the length and the amplitude of the wave but also the relation between the weight of the platform and the buoyancy force of the floats.
文摘Medicines are a global, strategic and diplomatic issue [1]. The UN General Secretary’s High Level Task Force [2] on Access to Medicines calls for a new approach to reduce the gap between medical innovations and access to medicines. Inequality in access to quality pharmaceutical products in a framework of global health democracy poses a threat to the ethical and equitable management of the provision of quality health care, particularly during global health crises. In French-speaking Africa, the lack of a unified production of pharmaceutical medicines forces wholesalers (public and private) to import almost all of their medicine demands resulting in a risk of dependence and major pharmaceutical quality defects. These central purchasing units are therefore often faced with the major challenge of guaranteeing the performance of their services and the security of their supplies. In order to achieve component 3 (“Access to Health”) of the SDOs (sustainable development goals), in particular the access to affordable medicines, it is essential for a country to have a strategy of pharmaceutical independence [3] by anticipating the epidemiological transition and the management of health crises. This strategy of pharmaceutical independence is based in the short and medium term on the strengthening of central purchasing units and the establishment of a public-private partnership between central purchasing units and wholesalers, and in the long term on the establishment of competitive production units that comply with international standards. However, recent health crises have shown the fragility of public central purchasing units and make it difficult to anticipate health crises.
文摘In the reform of government organizations and institutions of China, we put forward the establishment of personal account system in occupational pension, and the introduction of the "account" management model of the non real account accumulation. This paper analyzes the current situation of personal accounts in our country, and puts forward that the account rate of bank deposit can not resist inflation, and can not reflect the real return rate of China's pension funds, which is not conducive to the preservation and appreciation of personal account funds. On the basis of the above, the paper puts forward that the account rate should not only consider the level of economic development and inflation, but also to adapt to the financial payment ability, and establish the personal account risk reserve fund system and other improvement measures, and strive to achieve the sustainable development of the personal account system.
文摘In the new century, quantum technology has developed rapidly and has been applied in many fields. As an important aspect of the aerospace science, metrology and measuring science is a field which is influenced by the quantum technology dramatically. The new generation of the International System of Units will be redefined on the basis of the quantum theory. More and more new sensing techniques are developed taking into account quantum principles. In this paper, the influence of quantum technology on metrology and measuring science is introduced.
文摘The extensive research on public ethics in the local administration is more than necessary. This paper identifies the basic values of and the challenges to Macedonian Legal System in this area, and explains the key ethical aspects, which should be implemented in practice by civil servants, who increasingly have to learn how to perform in accordance with ethical values. In this paper I will analyze the ethical values of civil servants laid down by the Organization for Economic Co-operation and Development (OECD) and the Civil Servants Agency in Macedonia, upon which the ethical principles for civil servants in the local administration units are intended to be set. This paper deals with the ethics of civil servants, assessment of best practices, and evaluation of positive and negative indicators. The paper concludes with a few recommendations for the next steps in this process; and some criteria for the consideration of future developments are suggested.
文摘To investigate diagnostic accuracy of 2-hour protocol of rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion SPECT in chronic coronary artery disease. Sixty-seven patients with suspected CAD were enrolled in the prospective study. All patients underwent myocardial perfusion scintigraphy in SPECT with dual isotopes of T1-201 and dipyridamole stress Tc-99m sestamibi. Rest and stress imaging protocol were performed in 2 hours by dose of 3 mCi TI-201 and 25 mCi Tc-99m sestamibi. The acquisition parameters includes LEHR collimator, energy peak of 72 and 167 keV for T1-201 and 140 keV for Tc-99m, 180-degree rotation from RAO to LPO, matrix size 64x64, and 25second/frame/64 frames. The 20-segment model of left ventricle was used in automatic quantitation software. Coronary angiography was used as gold standard. CAD was defined as 50% of lumen stenosis on coronary angiography. Rest TI-201/stress tc-99m sestamibi dual-isotope SPECT demonstrated a sensitivity of 94.59% and specificity of 70%, positive predictive value of 79.54% and negative predictive value of 91.3% in detection of coronary artery disease. Sensitivity and specificity for detecting multi-vessel coronary artery disease were 82.75% and 81.57% for the left anterior descending, 77.77% and 91.83% for left circumflex and 94.11% and 82% for right coronary artery. 2-hour protocol of rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion SPECT has high sensitivity, specificity, positive predictive value and negative predictive value in detecting chronic coronary artery disease with greater than 50% stenosis assessed by coronary angiography Moreover, this imaging protocol gives high imaging quality, time-saving and convenience.
基金supported by the Young Scientists Fund of the National Natural Science Foundation of China(No.61204055)
文摘A 300 μm×300 μm light emitting diode(LED) chip is divided into nine 80 μm×80 μm units with 30 μm spacing between adjacent ones. After arraying, the total saturation light output power and the maximum injection current are enhanced by 5.19 times and nearly 7 times, respectively. In addition, the test results demonstrate that the illuminance uniformity on the receiving surface reaches the optimum when the spacing between the arrays is equal to the maximum flat condition. The larger the number of arrays, the greater the area with uniform illuminance on the receiving surface.
基金the National Natural Science Foundation of China (51273053, 21104012, 21284034 and 61106017)the Natural Science Foundation of Zhejiang Province (Y4110331)+1 种基金the Program for Changjiang Scholars and Innovative Research Teams in Chinese Universities (IRT 1231)the Project of Zhejiang Key Scientific and Technological Innovation Team (2010R50017)
文摘Tetraphenylethene (TPE) is a popular luminogen characterized by aggregation-induced emission and has been widely used to construct solid-state emissive materials. In this work, two thermally stable polymers (P1 and P2) consisting of TPE conjugated to the 2,7-positions of fluorene and carbazole, respectively, are synthesized and characterized. Both polymers are weakly fluorescent in solutions but show greatly enhanced emission as the aggregate formation, presenting an aggregation-enhanced emission feature. Two kinds of polymer light-emitting diodes are fabricated utilizing P1 and P2 as emitters (EML) (device I: ITO/PEDOT:PSS (45 nm)/PVK:EML (1:1 wt%, 55 nm)/TPBI (38 nm)/Ca:Ag; device II: ITO/PEDOT:PSS (45 nm)/ PVK:OXD-7:EML (3:1:3 wt%, 55 nm)/TPBI (38 nm)/Ca:Ag). The device II of P2 shows the best performances, affording a maximum luminance of 6500 cd/m 2 and a high peak efficiency of 2.11 cd/A.