目的：测定BPH患者尿道外括约肌运动单位电位（motor unit potential，MUP），统计出相应参数的正常值，为临床上发现“高危”BPH患者尿道外括约肌异常，降低“高危”BPH患者术后尿失禁发生率提供一定依据。方法：采用同心圆针电极经会...目的：测定BPH患者尿道外括约肌运动单位电位（motor unit potential，MUP），统计出相应参数的正常值，为临床上发现“高危”BPH患者尿道外括约肌异常，降低“高危”BPH患者术后尿失禁发生率提供一定依据。方法：采用同心圆针电极经会阴穿刺至尿道外括约肌，用尿动力仪记录肌电信号，测定并记录BPH患者尿道外括约肌MUP。结果：本研究测定BPH患者80例，对每例患者收集符合标准的电位5～10个，记录每个电位的时限和波幅，经统计学分析得出，BPH患者尿道外括约肌MUP的参考值时限为3．46～11．26ms，平均7．36ms，波幅为55～607μV，平均237μV。结论：本研究得出BPH患者的MuP正常值可以用来评估预测相关“高危”BPH患者的尿道外括约肌可能存在的神经肌肉病变，对避免及分析术后尿失禁的原因具有一定的临床运用价值。展开更多
Objective: Motor unit potential (MUP) morphology can bequantified using parame ters describing electrophysiological size and shape (complexity). Traditionally, MUP complexity has been estimated using parameters number...Objective: Motor unit potential (MUP) morphology can bequantified using parame ters describing electrophysiological size and shape (complexity). Traditionally, MUP complexity has been estimated using parameters number of phases and turns. Recently, ‘irregularity coefficient’(IR), measuring the length of the MUP curv e normalized with its amplitude, has been introduced. The aim of this study was to evaluate IR in the external anal sphincter muscle. Methods: Sensitivity was e xamined in 61 patients with chronic cauda equina lesions, and specificity in 75 controls using a standard concentric EMG needle and EMG system with multi-MUP a nalysis. Results: When evaluated separately the sensitivity of IR was 16%lower, and specificity 5%higher compared to number of turns, with both differences de creasing to only 2 and 1%, respectively, when each of these parameters was adde d to MUP area and duration.Conclusions: Our present results suggest that IR prov ides a similar diagnostic usefulness, but a more appropriate description of MUP complexity compared to traditional MUP parameters.Significance: IR seems to be s uitable to complement one of MUP parameters measuring electrophysiological MUP s ize in the future quantitative EMG.展开更多
Objective: In clinical electromyography, motor unit potential(MUP) size is use d to indicate the myo-or neurogenic origin of the pathological process, whereas the irregularity of MUP shape is considered not useful in ...Objective: In clinical electromyography, motor unit potential(MUP) size is use d to indicate the myo-or neurogenic origin of the pathological process, whereas the irregularity of MUP shape is considered not useful in this respect. The aim of the present study was to find a method to improve classification of MUPs usi ng a combined analysis of the size and irregularity of the potential. Methods: T he records with at least 20%of irregular potentials from 14 healthy subjects an d 34 patients were analysed. Principal Component Analysis (PCA) was applied in t he analysis of data to find a linear function combining the size and the irregul arity of a MUP. Results: The linear combination of size and irregularity measure s, i.e. size index (SI) and irregularity coefficient (IR) obtained using Princip al Component Analysis (PCA) did not increase the discriminating ability incompar ison to SI.We have defined a non-linear function of the SI and IR called SIIR, which modifies SI values for irregular potentials only. Its discriminating abili ty is higher than that of SI. Conclusions: By combined assessment of the size of a MUP and its irregularity, the differentiation between neurogenic and myopathi c potentials could be considerably improved. Significance:The proposed coefficie nt SIIR seems to be more discriminating than others presently used. When applied in clinical studies it may be useful in the evaluation of confusing,atypical mo tor unit potentials.展开更多
目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear ...目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear energy operator,SNEO)算法,对痉挛型脑瘫患儿表面肌电信号中的运动单位动作电位(motor unit action potential,MUAP)数目进行估计,获得MUAP的平均发放间隔(inter-pulse interval,IPI),并根据医生采用的分级结果和健康人MUAP平均发放时限的早期研究结果进行对比验证。结果对14名不同运动障碍级别脑瘫患者的实验结果显示,其肌电信号MUAP的IPI与他们活动度的级别即运动障碍的程度呈正相关的关系,且具有明显差异。结论研究结果表明本文方法有效,采用IPI参数能够反映脑瘫患儿的运动障碍程度。展开更多
目的探究大脑中动脉梗死后瘫痪肢体下运动神经元运动单位的改变及其影响因素。方法纳入40例单侧新发大脑中动脉梗死患者,分为皮质-基底节组(26例)与基底节组(14例),并纳入10例健康者为对照组。入院48 h内行NIHSS评分、m RS评分、Fugl-Me...目的探究大脑中动脉梗死后瘫痪肢体下运动神经元运动单位的改变及其影响因素。方法纳入40例单侧新发大脑中动脉梗死患者,分为皮质-基底节组(26例)与基底节组(14例),并纳入10例健康者为对照组。入院48 h内行NIHSS评分、m RS评分、Fugl-Meyer运动功能评分评估;于发病2~4周内行上下肢神经传导检测及拇短展肌运动单位数目估计(motor unit number estimation,MUNE)检测,同时采集单个运动单位电位(single motor unit action potential,SMUAP)数据,应用SPSS20.0进行数据分析。结果瘫痪侧肢体MUNE较健侧显著下降(皮质-基底节组:95.85±26.82 vs.143.65±38.86,P<0.001;基底节组:126.71±44.13 vs.157.36±56.72,P=0.001)且SMUAP波幅及面积显著增加(P<0.05),皮质-基底节组瘫痪侧肢体MUNE较基底节组显著下降(95.85±26.82 vs.161.40±48.90,P=0.027),MUNE与NIHSS评分(r=-0.339,P=0.032)及m RS评分(r=-0.362,P=0.022)呈显著负相关,入院时NIHSS评分(β=-1.603,P=0.032,95%CI:-3.064^-0.142)与m RS评分(OR=2.885,P=0.025,95%CI:1.139~7.158)均可预测瘫痪侧MUNE下降。结论大脑中动脉梗死后瘫痪肢体可见运动单位丢失和残存的运动单位代偿,急性期NIHSS评分、m RS评分可预测瘫痪侧运动单位的丢失。展开更多
文摘目的：测定BPH患者尿道外括约肌运动单位电位（motor unit potential，MUP），统计出相应参数的正常值，为临床上发现“高危”BPH患者尿道外括约肌异常，降低“高危”BPH患者术后尿失禁发生率提供一定依据。方法：采用同心圆针电极经会阴穿刺至尿道外括约肌，用尿动力仪记录肌电信号，测定并记录BPH患者尿道外括约肌MUP。结果：本研究测定BPH患者80例，对每例患者收集符合标准的电位5～10个，记录每个电位的时限和波幅，经统计学分析得出，BPH患者尿道外括约肌MUP的参考值时限为3．46～11．26ms，平均7．36ms，波幅为55～607μV，平均237μV。结论：本研究得出BPH患者的MuP正常值可以用来评估预测相关“高危”BPH患者的尿道外括约肌可能存在的神经肌肉病变，对避免及分析术后尿失禁的原因具有一定的临床运用价值。
文摘Objective: Motor unit potential (MUP) morphology can bequantified using parame ters describing electrophysiological size and shape (complexity). Traditionally, MUP complexity has been estimated using parameters number of phases and turns. Recently, ‘irregularity coefficient’(IR), measuring the length of the MUP curv e normalized with its amplitude, has been introduced. The aim of this study was to evaluate IR in the external anal sphincter muscle. Methods: Sensitivity was e xamined in 61 patients with chronic cauda equina lesions, and specificity in 75 controls using a standard concentric EMG needle and EMG system with multi-MUP a nalysis. Results: When evaluated separately the sensitivity of IR was 16%lower, and specificity 5%higher compared to number of turns, with both differences de creasing to only 2 and 1%, respectively, when each of these parameters was adde d to MUP area and duration.Conclusions: Our present results suggest that IR prov ides a similar diagnostic usefulness, but a more appropriate description of MUP complexity compared to traditional MUP parameters.Significance: IR seems to be s uitable to complement one of MUP parameters measuring electrophysiological MUP s ize in the future quantitative EMG.
文摘Objective: In clinical electromyography, motor unit potential(MUP) size is use d to indicate the myo-or neurogenic origin of the pathological process, whereas the irregularity of MUP shape is considered not useful in this respect. The aim of the present study was to find a method to improve classification of MUPs usi ng a combined analysis of the size and irregularity of the potential. Methods: T he records with at least 20%of irregular potentials from 14 healthy subjects an d 34 patients were analysed. Principal Component Analysis (PCA) was applied in t he analysis of data to find a linear function combining the size and the irregul arity of a MUP. Results: The linear combination of size and irregularity measure s, i.e. size index (SI) and irregularity coefficient (IR) obtained using Princip al Component Analysis (PCA) did not increase the discriminating ability incompar ison to SI.We have defined a non-linear function of the SI and IR called SIIR, which modifies SI values for irregular potentials only. Its discriminating abili ty is higher than that of SI. Conclusions: By combined assessment of the size of a MUP and its irregularity, the differentiation between neurogenic and myopathi c potentials could be considerably improved. Significance:The proposed coefficie nt SIIR seems to be more discriminating than others presently used. When applied in clinical studies it may be useful in the evaluation of confusing,atypical mo tor unit potentials.
文摘目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear energy operator,SNEO)算法,对痉挛型脑瘫患儿表面肌电信号中的运动单位动作电位(motor unit action potential,MUAP)数目进行估计,获得MUAP的平均发放间隔(inter-pulse interval,IPI),并根据医生采用的分级结果和健康人MUAP平均发放时限的早期研究结果进行对比验证。结果对14名不同运动障碍级别脑瘫患者的实验结果显示,其肌电信号MUAP的IPI与他们活动度的级别即运动障碍的程度呈正相关的关系,且具有明显差异。结论研究结果表明本文方法有效,采用IPI参数能够反映脑瘫患儿的运动障碍程度。
文摘目的探究大脑中动脉梗死后瘫痪肢体下运动神经元运动单位的改变及其影响因素。方法纳入40例单侧新发大脑中动脉梗死患者,分为皮质-基底节组(26例)与基底节组(14例),并纳入10例健康者为对照组。入院48 h内行NIHSS评分、m RS评分、Fugl-Meyer运动功能评分评估;于发病2~4周内行上下肢神经传导检测及拇短展肌运动单位数目估计(motor unit number estimation,MUNE)检测,同时采集单个运动单位电位(single motor unit action potential,SMUAP)数据,应用SPSS20.0进行数据分析。结果瘫痪侧肢体MUNE较健侧显著下降(皮质-基底节组:95.85±26.82 vs.143.65±38.86,P<0.001;基底节组:126.71±44.13 vs.157.36±56.72,P=0.001)且SMUAP波幅及面积显著增加(P<0.05),皮质-基底节组瘫痪侧肢体MUNE较基底节组显著下降(95.85±26.82 vs.161.40±48.90,P=0.027),MUNE与NIHSS评分(r=-0.339,P=0.032)及m RS评分(r=-0.362,P=0.022)呈显著负相关,入院时NIHSS评分(β=-1.603,P=0.032,95%CI:-3.064^-0.142)与m RS评分(OR=2.885,P=0.025,95%CI:1.139~7.158)均可预测瘫痪侧MUNE下降。结论大脑中动脉梗死后瘫痪肢体可见运动单位丢失和残存的运动单位代偿,急性期NIHSS评分、m RS评分可预测瘫痪侧运动单位的丢失。
